| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0487785 |
| CDH6 | cadherin 6, type 2, K-cadherin (fetal kidney) | 0.0397034 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0316697 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0306637 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0292281 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0283082 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0252394 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0246565 |
| ISG15 | ISG15 ubiquitin-like modifier | 0.0243948 |
| HERC5 | HECT and RLD domain containing E3 ubiquitin protein ligase 5 | 0.023078 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0224936 |
| CENPE | centromere protein E, 312kDa | 0.0224031 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0222193 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0215978 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0211272 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0206705 |
| TMSB4X | thymosin beta 4, X-linked | 0.0202893 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0202248 |
| IFIH1 | interferon induced with helicase C domain 1 | 0.0198948 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0197141 |
| PTMA | prothymosin, alpha | 0.0196891 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0193369 |
| SON | SON DNA binding protein | 0.0185834 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0182381 |
| FILIP1 | filamin A interacting protein 1 | 0.0178188 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0178166 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | 0.0175809 |
| CUL4B | cullin 4B | 0.0174646 |
| VCL | vinculin | 0.0174638 |
| CDH8 | cadherin 8, type 2 | 0.0172219 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0168387 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0167377 |
| BRD2 | bromodomain containing 2 | 0.0166714 |
| GOLGB1 | golgin B1 | 0.0163724 |
| MT2A | metallothionein 2A | 0.0162071 |
| PLEKHG1 | pleckstrin homology domain containing, family G (with RhoGef domain) member 1 | 0.0159761 |
| CEP250 | centrosomal protein 250kDa | 0.0158962 |
| BRCC3 | BRCA1/BRCA2-containing complex, subunit 3 | 0.0157893 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | 0.015713 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0154014 |
| FGF13 | fibroblast growth factor 13 | 0.0153918 |
| ICE1 | interactor of little elongation complex ELL subunit 1 | 0.0151403 |
| TENM2 | teneurin transmembrane protein 2 | 0.0150575 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0149953 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0149813 |
| MAP2K4 | mitogen-activated protein kinase kinase 4 | 0.0147986 |
| RPS6KC1 | ribosomal protein S6 kinase, 52kDa, polypeptide 1 | 0.0146702 |
| MSN | moesin | 0.0146612 |
| ZNF217 | zinc finger protein 217 | 0.0146352 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0145626 |
| IP6K1 | inositol hexakisphosphate kinase 1 | 0.0144049 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0140831 |
| CDC14A | cell division cycle 14A | 0.0140576 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0139894 |
| PYGL | phosphorylase, glycogen, liver | 0.013959 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | 0.0137055 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0135612 |
| NCOA7 | nuclear receptor coactivator 7 | 0.0135309 |
| DIAPH3 | diaphanous-related formin 3 | 0.013499 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0134864 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0133696 |
| RIGI | RNA sensor RIG-I | 0.0132866 |
| USP26 | ubiquitin specific peptidase 26 | 0.013188 |
| BTBD3 | BTB (POZ) domain containing 3 | 0.0131566 |
| WDR75 | WD repeat domain 75 | 0.0131394 |
| PDE10A | phosphodiesterase 10A | 0.0131177 |
| OASL | 2'-5'-oligoadenylate synthetase-like | 0.01309 |
| KNTC1 | kinetochore associated 1 | 0.0130357 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0129171 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | 0.0128988 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.0128787 |
| FAM219A | family with sequence similarity 219, member A | 0.0128777 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0128697 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0127401 |
| MEF2C | myocyte enhancer factor 2C | 0.0127031 |
| IRF1 | interferon regulatory factor 1 | 0.0126632 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.01262 |
| UTRN | utrophin | 0.0125893 |
| DNAJB6 | DnaJ (Hsp40) homolog, subfamily B, member 6 | 0.0125041 |
| CLSPN | claspin | 0.0124766 |
| MAD1L1 | MAD1 mitotic arrest deficient-like 1 (yeast) | 0.0124094 |
| NONO | non-POU domain containing, octamer-binding | 0.0123495 |
| TMCO3 | transmembrane and coiled-coil domains 3 | 0.0123381 |
| INTS6 | integrator complex subunit 6 | 0.0123173 |
| LMO7 | LIM domain 7 | 0.0123146 |
| UBN2 | ubinuclein 2 | 0.012299 |
| SNCA | synuclein, alpha (non A4 component of amyloid precursor) | 0.0122738 |
| RBM26 | RNA binding motif protein 26 | 0.0122637 |
| SMAD6 | SMAD family member 6 | 0.012252 |
| CSTF3 | cleavage stimulation factor, 3' pre-RNA, subunit 3, 77kDa | 0.0122395 |
| INTS4 | integrator complex subunit 4 | 0.0122217 |
| SRSF9 | serine/arginine-rich splicing factor 9 | 0.0122061 |
| ANKLE2 | ankyrin repeat and LEM domain containing 2 | 0.0120969 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0120667 |
| RPSA | ribosomal protein SA | 0.0120552 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0119908 |
| EIF5AL1 | eukaryotic translation initiation factor 5A-like 1 | 0.0119215 |
| ZNF146 | zinc finger protein 146 | 0.0119176 |
| PROC | protein C (inactivator of coagulation factors Va and VIIIa) | 0.0119079 |
| GATAD2A | GATA zinc finger domain containing 2A | 0.0118954 |
| Symbol | Name | Standardized Value |
|---|---|---|
| COL11A1 | collagen, type XI, alpha 1 | -0.139628 |
| VIM | vimentin | -0.107167 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0957105 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0897158 |
| ITGAV | integrin, alpha V | -0.0895148 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0854714 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0813295 |
| CADM2 | cell adhesion molecule 2 | -0.0795723 |
| CTNNA3 | catenin (cadherin-associated protein), alpha 3 | -0.0780151 |
| PRTG | protogenin | -0.0744679 |
| SRP54 | signal recognition particle 54kDa | -0.0715161 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0705084 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0697047 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0683713 |
| SNX6 | sorting nexin 6 | -0.068226 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0631925 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | -0.0618082 |
| COL1A2 | collagen, type I, alpha 2 | -0.0616957 |
| MDK | midkine (neurite growth-promoting factor 2) | -0.0609536 |
| LRRC4C | leucine rich repeat containing 4C | -0.0567506 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0560239 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0558648 |
| NCAM2 | neural cell adhesion molecule 2 | -0.0548173 |
| PGK1 | phosphoglycerate kinase 1 | -0.0540871 |
| ENAH | enabled homolog (Drosophila) | -0.0536018 |
| KHDRBS1 | KH domain containing, RNA binding, signal transduction associated 1 | -0.0515425 |
| RPS8 | ribosomal protein S8 | -0.0514552 |
| RPS6 | ribosomal protein S6 | -0.0507387 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | -0.0500667 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0498874 |
| PFN1 | profilin 1 | -0.0480571 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0475081 |
| WASF2 | WAS protein family, member 2 | -0.0471077 |
| PHIP | pleckstrin homology domain interacting protein | -0.0470507 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0470261 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0465668 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0465476 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0451462 |
| TMSB10 | thymosin beta 10 | -0.0444602 |
| ANK2 | ankyrin 2, neuronal | -0.0442371 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0440999 |
| ZNF292 | zinc finger protein 292 | -0.0438586 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.043709 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0418221 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0413504 |
| RPS16 | ribosomal protein S16 | -0.0413306 |
| PLPP1 | phospholipid phosphatase 1 | -0.0410914 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0410138 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.040901 |
| RLF | rearranged L-myc fusion | -0.0402625 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0402155 |
| MEIS2 | Meis homeobox 2 | -0.0396474 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | -0.0392195 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.039142 |
| RPL5 | ribosomal protein L5 | -0.0384197 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0383896 |
| RTN4 | reticulon 4 | -0.0380413 |
| THOC2 | THO complex 2 | -0.0378571 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0370161 |
| TOX | thymocyte selection-associated high mobility group box | -0.0369037 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | -0.0367906 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0366125 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0359002 |
| SRPK2 | SRSF protein kinase 2 | -0.035653 |
| SORBS2 | sorbin and SH3 domain containing 2 | -0.0355381 |
| PCBP2 | poly(rC) binding protein 2 | -0.0354367 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0353162 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0352404 |
| H3-3B | H3.3 histone B | -0.0351698 |
| RPL35A | ribosomal protein L35a | -0.0344933 |
| CALR | calreticulin | -0.0344558 |
| CDH10 | cadherin 10, type 2 (T2-cadherin) | -0.0340602 |
| UPP1 | uridine phosphorylase 1 | -0.034045 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0334519 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0332329 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0330487 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0329894 |
| TUBA1B | tubulin, alpha 1b | -0.0324667 |
| GPC3 | glypican 3 | -0.0320353 |
| TENM3 | teneurin transmembrane protein 3 | -0.0319533 |
| ATXN2 | ataxin 2 | -0.0316115 |
| EVI5 | ecotropic viral integration site 5 | -0.0314387 |
| FBXO17 | F-box protein 17 | -0.0313808 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0310887 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0308178 |
| TCF12 | transcription factor 12 | -0.0304662 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0302376 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0301323 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0300989 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0299081 |
| POTEF | POTE ankyrin domain family, member F | -0.0299016 |
| PSMA6 | proteasome (prosome, macropain) subunit, alpha type, 6 | -0.0297831 |
| RPLP1 | ribosomal protein, large, P1 | -0.0297627 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0297147 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0293921 |
| RBM39 | RNA binding motif protein 39 | -0.0291985 |
| WDR43 | WD repeat domain 43 | -0.0290199 |
| RPL11 | ribosomal protein L11 | -0.0289038 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0287493 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0287385 |
