| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Darinaparsin_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.144872 |
| EGFR | epidermal growth factor receptor | 0.0678459 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.041131 |
| PDGFC | platelet derived growth factor C | 0.0390047 |
| MYO5C | myosin VC | 0.0360237 |
| ZNF608 | zinc finger protein 608 | 0.0334107 |
| MT2A | metallothionein 2A | 0.03185 |
| ASPH | aspartate beta-hydroxylase | 0.0301579 |
| SMYD3 | SET and MYND domain containing 3 | 0.0295002 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0275723 |
| RPS12 | ribosomal protein S12 | 0.0272033 |
| ECT2 | epithelial cell transforming 2 | 0.0266888 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0262914 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0262063 |
| INTS6 | integrator complex subunit 6 | 0.0252738 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0240615 |
| ZNF217 | zinc finger protein 217 | 0.0239961 |
| ARL15 | ADP-ribosylation factor-like 15 | 0.0238011 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0228529 |
| GALNT5 | polypeptide N-acetylgalactosaminyltransferase 5 | 0.0224029 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.0222872 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0221339 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0218582 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0217467 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0214533 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0202179 |
| RPS15A | ribosomal protein S15a | 0.0201989 |
| H1-4 | H1.4 linker histone, cluster member | 0.0201988 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0199329 |
| AGPS | alkylglycerone phosphate synthase | 0.0198524 |
| AHCYL2 | adenosylhomocysteinase-like 2 | 0.0192933 |
| ITCH | itchy E3 ubiquitin protein ligase | 0.0187855 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0186005 |
| KLC1 | kinesin light chain 1 | 0.0182689 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0182257 |
| RAD50 | RAD50 homolog (S. cerevisiae) | 0.0180849 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0179987 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.0179003 |
| PARD3B | par-3 family cell polarity regulator beta | 0.0178682 |
| ANXA1 | annexin A1 | 0.017626 |
| FNIP1 | folliculin interacting protein 1 | 0.0174558 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.017324 |
| SP100 | SP100 nuclear antigen | 0.0170499 |
| TRIM56 | tripartite motif containing 56 | 0.0170365 |
| AEBP2 | AE binding protein 2 | 0.0168611 |
| MCL1 | myeloid cell leukemia 1 | 0.0168027 |
| LMO7 | LIM domain 7 | 0.0167276 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0166258 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | 0.016553 |
| CREBBP | CREB binding protein | 0.0164966 |
| ATP13A3 | ATPase type 13A3 | 0.0164431 |
| LAMA4 | laminin, alpha 4 | 0.0164246 |
| RNF213 | ring finger protein 213 | 0.0163434 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0162623 |
| CSNK1G1 | casein kinase 1, gamma 1 | 0.0162238 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0158153 |
| CHCHD3 | coiled-coil-helix-coiled-coil-helix domain containing 3 | 0.015714 |
| LAMB3 | laminin, beta 3 | 0.0156023 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | 0.0155789 |
| TGFBR3 | transforming growth factor, beta receptor III | 0.0155176 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0154789 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0154009 |
| TIAM2 | T-cell lymphoma invasion and metastasis 2 | 0.0153778 |
| RBM33 | RNA binding motif protein 33 | 0.0153215 |
| ZFHX3 | zinc finger homeobox 3 | 0.0152077 |
| SATB2 | SATB homeobox 2 | 0.0151869 |
| APP | amyloid beta (A4) precursor protein | 0.0151553 |
| UTRN | utrophin | 0.0151484 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0151062 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.015088 |
| R3HDM2 | R3H domain containing 2 | 0.0150798 |
| HS2ST1 | heparan sulfate 2-O-sulfotransferase 1 | 0.0150208 |
| CLTC | clathrin, heavy chain (Hc) | 0.0147785 |
| SET | SET nuclear proto-oncogene | 0.0146942 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.014542 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0144507 |
| TPP2 | tripeptidyl peptidase II | 0.0143778 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0143593 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0143375 |
| RPL37A | ribosomal protein L37a | 0.0141608 |
| PRPF40A | PRP40 pre-mRNA processing factor 40 homolog A (S. cerevisiae) | 0.0141595 |
| HDAC4 | histone deacetylase 4 | 0.0140774 |
| ARHGAP25 | Rho GTPase activating protein 25 | 0.014055 |
| RAB21 | RAB21, member RAS oncogene family | 0.0138885 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | 0.0138628 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.013831 |
| PARP6 | poly (ADP-ribose) polymerase family, member 6 | 0.013785 |
| CCT5 | chaperonin containing TCP1, subunit 5 (epsilon) | 0.0137722 |
| PRELID2 | PRELI domain containing 2 | 0.0137298 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | 0.0136944 |
| FAM120B | family with sequence similarity 120B | 0.0136913 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | 0.0136086 |
| SCAF8 | SR-related CTD-associated factor 8 | 0.0135782 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0135677 |
| POGZ | pogo transposable element with ZNF domain | 0.0133914 |
| ELP4 | elongator acetyltransferase complex subunit 4 | 0.013383 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0133505 |
| ULK4 | unc-51 like kinase 4 | 0.0133062 |
| GLIS3 | GLIS family zinc finger 3 | 0.0132901 |
| RAB11FIP3 | RAB11 family interacting protein 3 (class II) | 0.0132854 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.448389 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.136305 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.131796 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.127224 |
| PKM | pyruvate kinase, muscle | -0.111418 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.109732 |
| PTMA | prothymosin, alpha | -0.0953978 |
| RPS6 | ribosomal protein S6 | -0.0927878 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0866561 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | -0.0841138 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0758346 |
| CCND1 | cyclin D1 | -0.0748353 |
| MKI67 | marker of proliferation Ki-67 | -0.0740023 |
| BMP10 | bone morphogenetic protein 10 | -0.0731258 |
| ACTG1 | actin gamma 1 | -0.0730038 |
| POTEF | POTE ankyrin domain family, member F | -0.0726905 |
| RPL35A | ribosomal protein L35a | -0.0722865 |
| GOLGA4 | golgin A4 | -0.0641965 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0631753 |
| PFN1 | profilin 1 | -0.062376 |
| RPS13 | ribosomal protein S13 | -0.0615898 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0612764 |
| NBEA | neurobeachin | -0.0605846 |
| RHOA | ras homolog family member A | -0.060563 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.05914 |
| EVI5 | ecotropic viral integration site 5 | -0.0586508 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0583332 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0581277 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0564511 |
| RTN4 | reticulon 4 | -0.0543099 |
| LDHA | lactate dehydrogenase A | -0.0537775 |
| RPS23 | ribosomal protein S23 | -0.0513423 |
| BMP2K | BMP2 inducible kinase | -0.0485816 |
| FLNB | filamin B, beta | -0.048365 |
| RPS8 | ribosomal protein S8 | -0.0476049 |
| TPM4 | tropomyosin 4 | -0.0465154 |
| GPHN | gephyrin | -0.046109 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0453432 |
| TNFRSF11B | tumor necrosis factor receptor superfamily, member 11b | -0.0433289 |
| JMJD1C | jumonji domain containing 1C | -0.0431496 |
| RPL8 | ribosomal protein L8 | -0.043068 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | -0.0429369 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0422303 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.0419192 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0417282 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0416157 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0409634 |
| RPLP1 | ribosomal protein, large, P1 | -0.0402178 |
| S100A9 | S100 calcium binding protein A9 | -0.0398302 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0395805 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0395656 |
| RPL28 | ribosomal protein L28 | -0.039084 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0390644 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0387372 |
| SBF2 | SET binding factor 2 | -0.0384551 |
| GNAS | GNAS complex locus | -0.0377871 |
| IBTK | inhibitor of Bruton agammaglobulinemia tyrosine kinase | -0.0374089 |
| S100A4 | S100 calcium binding protein A4 | -0.0372721 |
| RPL3 | ribosomal protein L3 | -0.037212 |
| VCL | vinculin | -0.0371449 |
| PCBP2 | poly(rC) binding protein 2 | -0.0366469 |
| RPS25 | ribosomal protein S25 | -0.036099 |
| RPLP0 | ribosomal protein, large, P0 | -0.0354216 |
| HJURP | Holliday junction recognition protein | -0.0351543 |
| FOXP1 | forkhead box P1 | -0.0349419 |
| TOB1 | transducer of ERBB2, 1 | -0.0344895 |
| SMC3 | structural maintenance of chromosomes 3 | -0.033967 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0338465 |
| GCNT1 | glucosaminyl (N-acetyl) transferase 1, core 2 | -0.0335423 |
| RPL19 | ribosomal protein L19 | -0.0333068 |
| PYGB | phosphorylase, glycogen; brain | -0.0329797 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0328896 |
| CENPF | centromere protein F, 350/400kDa | -0.0325603 |
| FAM13A | family with sequence similarity 13, member A | -0.0322181 |
| HMGA1 | high mobility group AT-hook 1 | -0.03215 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320714 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0318823 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0317874 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.031594 |
| ZNF292 | zinc finger protein 292 | -0.0311552 |
| TXNIP | thioredoxin interacting protein | -0.0311515 |
| DIAPH2 | diaphanous-related formin 2 | -0.0308184 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0307869 |
| MATR3 | matrin 3 | -0.0304444 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0302419 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.030187 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.0299376 |
| SEPTIN7 | septin 7 | -0.0299293 |
| RPS16 | ribosomal protein S16 | -0.0297726 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | -0.0296586 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0296146 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0294915 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0293354 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0291153 |
| CNOT6L | CCR4-NOT transcription complex, subunit 6-like | -0.0290001 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0289836 |
| DIAPH3 | diaphanous-related formin 3 | -0.028923 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.028863 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.0288079 |
| CAMTA1 | calmodulin binding transcription activator 1 | -0.0287897 |
