| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Darinaparsin_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.221754 |
| VIM | vimentin | 0.214531 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.154344 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0927823 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0872724 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0837119 |
| HDAC9 | histone deacetylase 9 | 0.07946 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0784462 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0690294 |
| HLA-E | major histocompatibility complex, class I, E | 0.067533 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0658883 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0612178 |
| HMGA2 | high mobility group AT-hook 2 | 0.0610775 |
| PLIN2 | perilipin 2 | 0.0599542 |
| ADM | adrenomedullin | 0.0588363 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0586206 |
| RPS12 | ribosomal protein S12 | 0.0569499 |
| GLIS3 | GLIS family zinc finger 3 | 0.054971 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0519856 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.048915 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0450677 |
| STC1 | stanniocalcin 1 | 0.0449016 |
| HLA-A | major histocompatibility complex, class I, A | 0.0446602 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0444858 |
| LDHA | lactate dehydrogenase A | 0.0442012 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0422827 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0420722 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0413812 |
| SQSTM1 | sequestosome 1 | 0.0408175 |
| RPS3 | ribosomal protein S3 | 0.0394971 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0389209 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0387276 |
| INTS6 | integrator complex subunit 6 | 0.0382346 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0371858 |
| ENO1 | enolase 1, (alpha) | 0.0361685 |
| VCAN | versican | 0.035542 |
| AFF3 | AF4/FMR2 family, member 3 | 0.0354044 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0352886 |
| RPL37A | ribosomal protein L37a | 0.0349944 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0346099 |
| COL5A1 | collagen, type V, alpha 1 | 0.0345048 |
| EGFR | epidermal growth factor receptor | 0.0344702 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0343973 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | 0.0343512 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | 0.0341143 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0340817 |
| CANX | calnexin | 0.0326706 |
| EFNA5 | ephrin-A5 | 0.0326009 |
| BRD2 | bromodomain containing 2 | 0.0321252 |
| FLNB | filamin B, beta | 0.0317926 |
| B2M | beta-2-microglobulin | 0.0314268 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0311776 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0305762 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0303928 |
| IER2 | immediate early response 2 | 0.029288 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0292443 |
| TMSB10 | thymosin beta 10 | 0.0290936 |
| TMSB4X | thymosin beta 4, X-linked | 0.0290864 |
| FRMPD4 | FERM and PDZ domain containing 4 | 0.0281616 |
| KYNU | kynureninase | 0.0279594 |
| NAV1 | neuron navigator 1 | 0.0275242 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0270502 |
| RPL7A | ribosomal protein L7a | 0.0258284 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0257865 |
| LOX | lysyl oxidase | 0.0256817 |
| ANGPTL4 | angiopoietin-like 4 | 0.0253905 |
| INHBA | inhibin, beta A | 0.0253706 |
| RPL31 | ribosomal protein L31 | 0.0253656 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0251199 |
| PRELID2 | PRELI domain containing 2 | 0.024996 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0249444 |
| AHNAK | AHNAK nucleoprotein | 0.0248503 |
| FTL | ferritin, light polypeptide | 0.0243862 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0243465 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | 0.0239438 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.02388 |
| PGK1 | phosphoglycerate kinase 1 | 0.0234351 |
| GPC6 | glypican 6 | 0.0233991 |
| CALR | calreticulin | 0.023327 |
| TMEM132D | transmembrane protein 132D | 0.023148 |
| FUT11 | fucosyltransferase 11 (alpha (1,3) fucosyltransferase) | 0.0229512 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | 0.0228085 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0226134 |
| ZBTB38 | zinc finger and BTB domain containing 38 | 0.0224251 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0224108 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0223136 |
| ASPH | aspartate beta-hydroxylase | 0.0222615 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0221892 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0221756 |
| DOCK5 | dedicator of cytokinesis 5 | 0.022127 |
| CEP250 | centrosomal protein 250kDa | 0.0220772 |
| KAT6B | K(lysine) acetyltransferase 6B | 0.0219663 |
| ZNF608 | zinc finger protein 608 | 0.0213148 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | 0.0212042 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | 0.0210581 |
| FMNL2 | formin-like 2 | 0.0210359 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0210253 |
| ABHD12 | abhydrolase domain containing 12 | 0.0208207 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0206596 |
| STAG2 | stromal antigen 2 | 0.0205408 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | -0.146385 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.136735 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.126377 |
| FN1 | fibronectin 1 | -0.122527 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.110677 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.105856 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0987334 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0754974 |
| RTN4 | reticulon 4 | -0.0591653 |
| CD44 | CD44 molecule (Indian blood group) | -0.0571943 |
| ZNF292 | zinc finger protein 292 | -0.0547037 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0498452 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0487993 |
| VCL | vinculin | -0.0457074 |
| POTEF | POTE ankyrin domain family, member F | -0.045673 |
| OSMR | oncostatin M receptor | -0.0443023 |
| ICAM1 | intercellular adhesion molecule 1 | -0.0437777 |
| CENPF | centromere protein F, 350/400kDa | -0.0428315 |
| TAPBP | TAP binding protein (tapasin) | -0.0419867 |
| NAV2 | neuron navigator 2 | -0.0401833 |
| TXNRD1 | thioredoxin reductase 1 | -0.0394075 |
| SNX9 | sorting nexin 9 | -0.0391913 |
| ARF4 | ADP-ribosylation factor 4 | -0.0391352 |
| CDCP1 | CUB domain containing protein 1 | -0.0388005 |
| ANXA2 | annexin A2 | -0.0377265 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0377103 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0373409 |
| MKI67 | marker of proliferation Ki-67 | -0.0368946 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0361359 |
| TPM1 | tropomyosin 1 (alpha) | -0.0323777 |
| RBM39 | RNA binding motif protein 39 | -0.0306992 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0303402 |
| THBS1 | thrombospondin 1 | -0.0301114 |
| CCNL1 | cyclin L1 | -0.0298456 |
| CALD1 | caldesmon 1 | -0.0288447 |
| MX1 | MX dynamin-like GTPase 1 | -0.0288174 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0285007 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0279091 |
| ACTG1 | actin gamma 1 | -0.0278466 |
| TPM4 | tropomyosin 4 | -0.0277834 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0276129 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0275702 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0271961 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | -0.0268732 |
| RUNX1 | runt-related transcription factor 1 | -0.0256669 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0254932 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.0253381 |
| SBF2 | SET binding factor 2 | -0.0251428 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.024941 |
| FOSL1 | FOS-like antigen 1 | -0.0246669 |
| GNAS | GNAS complex locus | -0.0246025 |
| WTAP | Wilms tumor 1 associated protein | -0.0245053 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0243131 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0242437 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0240545 |
| JMJD1C | jumonji domain containing 1C | -0.0237781 |
| RUNX2 | runt-related transcription factor 2 | -0.0236189 |
| FAM3C | family with sequence similarity 3, member C | -0.0231999 |
| NRP1 | neuropilin 1 | -0.0231474 |
| PLSCR1 | phospholipid scramblase 1 | -0.0230997 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0230797 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0229992 |
| SYAP1 | synapse associated protein 1 | -0.0229522 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0229251 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0228007 |
| CTSD | cathepsin D | -0.0227398 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0227278 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | -0.0225326 |
| YBX1 | Y box binding protein 1 | -0.0225224 |
| TM9SF3 | transmembrane 9 superfamily member 3 | -0.0223349 |
| RRBP1 | ribosome binding protein 1 | -0.0221712 |
| TRAF3IP2 | TRAF3 interacting protein 2 | -0.0220124 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0217663 |
| DEK | DEK proto-oncogene | -0.0214502 |
| SPAG9 | sperm associated antigen 9 | -0.0212079 |
| USP3 | ubiquitin specific peptidase 3 | -0.0209269 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.020543 |
| COL1A1 | collagen, type I, alpha 1 | -0.0203976 |
| HMGA1 | high mobility group AT-hook 1 | -0.0201364 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0200651 |
| TNNC1 | troponin C type 1 (slow) | -0.019943 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0198099 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0197961 |
| SRGN | serglycin | -0.0197682 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0196015 |
| NDRG1 | N-myc downstream regulated 1 | -0.0195706 |
| EGR1 | early growth response 1 | -0.0195292 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0194954 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0193723 |
| TRIP12 | thyroid hormone receptor interactor 12 | -0.0191318 |
| HIPK3 | homeodomain interacting protein kinase 3 | -0.0191285 |
| PPP2CA | protein phosphatase 2, catalytic subunit, alpha isozyme | -0.0190956 |
| PLPP4 | phospholipid phosphatase 4 | -0.0189125 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0188971 |
| USP12 | ubiquitin specific peptidase 12 | -0.0188445 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0188434 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0188132 |
| ATP2A2 | ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 | -0.0187039 |
| TMEM123 | transmembrane protein 123 | -0.0186841 |
| EXT1 | exostosin glycosyltransferase 1 | -0.018569 |
