| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| MYH9 | myosin, heavy chain 9, non-muscle | 0.205781 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0598169 |
| KYNU | kynureninase | 0.0554233 |
| MAP1B | microtubule-associated protein 1B | 0.0478894 |
| HMGA2 | high mobility group AT-hook 2 | 0.0424869 |
| HIP1 | huntingtin interacting protein 1 | 0.0403195 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0383491 |
| CD44 | CD44 molecule (Indian blood group) | 0.0372636 |
| SMAD3 | SMAD family member 3 | 0.0372276 |
| AHNAK | AHNAK nucleoprotein | 0.0371648 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.03522 |
| FLNA | filamin A, alpha | 0.0342365 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0340096 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0336782 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0335122 |
| AHR | aryl hydrocarbon receptor | 0.0329996 |
| MSN | moesin | 0.0323525 |
| PDLIM5 | PDZ and LIM domain 5 | 0.032057 |
| ACTN1 | actinin, alpha 1 | 0.0320406 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0312064 |
| AUTS2 | autism susceptibility candidate 2 | 0.0304815 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0302 |
| INTS6 | integrator complex subunit 6 | 0.030089 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0294215 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0272721 |
| LAMB1 | laminin, beta 1 | 0.0272709 |
| CENPF | centromere protein F, 350/400kDa | 0.0268337 |
| ASPH | aspartate beta-hydroxylase | 0.0267413 |
| DNAH11 | dynein, axonemal, heavy chain 11 | 0.0265956 |
| DIAPH3 | diaphanous-related formin 3 | 0.0256664 |
| AOPEP | aminopeptidase O (putative) | 0.0254864 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0247903 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0246246 |
| COL4A1 | collagen, type IV, alpha 1 | 0.0242516 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.02411 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0240157 |
| RBFOX2 | RNA binding protein, fox-1 homolog (C. elegans) 2 | 0.0236641 |
| SETBP1 | SET binding protein 1 | 0.0234227 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | 0.0231442 |
| PLEC | plectin | 0.0227413 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0226864 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0224612 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0224504 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0220159 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0218275 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0217832 |
| ACTN4 | actinin, alpha 4 | 0.0217049 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0213841 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0213644 |
| PMEPA1 | prostate transmembrane protein, androgen induced 1 | 0.0213508 |
| USP47 | ubiquitin specific peptidase 47 | 0.0209652 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | 0.0209027 |
| VCL | vinculin | 0.0206866 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0206533 |
| SYNJ2 | synaptojanin 2 | 0.0204221 |
| ATXN1 | ataxin 1 | 0.0200727 |
| TPI1 | triosephosphate isomerase 1 | 0.0199532 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | 0.0198042 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0197468 |
| EML4 | echinoderm microtubule associated protein like 4 | 0.0197464 |
| PRELID2 | PRELI domain containing 2 | 0.0193622 |
| ENO1 | enolase 1, (alpha) | 0.0192663 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | 0.0191303 |
| TMED7 | transmembrane emp24 protein transport domain containing 7 | 0.0189514 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.018799 |
| HOMER2 | homer scaffolding protein 2 | 0.0187468 |
| MED13L | mediator complex subunit 13-like | 0.0184863 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0182353 |
| MB21D2 | Mab-21 domain containing 2 | 0.0181927 |
| PHF14 | PHD finger protein 14 | 0.0181642 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0181603 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0181166 |
| SMYD3 | SET and MYND domain containing 3 | 0.0179139 |
| TLN1 | talin 1 | 0.0177771 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0177616 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0177253 |
| WWOX | WW domain containing oxidoreductase | 0.0177186 |
| JMJD1C | jumonji domain containing 1C | 0.017692 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0174705 |
| EXOC4 | exocyst complex component 4 | 0.0174208 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0171467 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | 0.0171251 |
| PCM1 | pericentriolar material 1 | 0.0170912 |
| LARGE1 | LARGE xylosyl- and glucuronyltransferase 1 | 0.0170577 |
| ITGAV | integrin, alpha V | 0.0170342 |
| WASL | Wiskott-Aldrich syndrome-like | 0.0170087 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0170083 |
| TOP1 | topoisomerase (DNA) I | 0.01669 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0166657 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.016609 |
| PID1 | phosphotyrosine interaction domain containing 1 | 0.0165942 |
| NRXN3 | neurexin 3 | 0.0164843 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0163663 |
| SLC14A1 | solute carrier family 14 (urea transporter), member 1 (Kidd blood group) | 0.0162054 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0161998 |
| RNF216 | ring finger protein 216 | 0.0161537 |
| ABL1 | ABL proto-oncogene 1, non-receptor tyrosine kinase | 0.0160895 |
| GTF2IRD1 | GTF2I repeat domain containing 1 | 0.0160703 |
| NAV1 | neuron navigator 1 | 0.0159551 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0159545 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.311332 |
| HLA-B | major histocompatibility complex, class I, B | -0.124506 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.117139 |
| NDRG1 | N-myc downstream regulated 1 | -0.109892 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0910494 |
| FTL | ferritin, light polypeptide | -0.0867799 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0840319 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0816544 |
| IL6 | interleukin 6 | -0.0816496 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0805175 |
| TMSB10 | thymosin beta 10 | -0.0763023 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0733944 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0655924 |
| VIM | vimentin | -0.0655858 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0647759 |
| POTEF | POTE ankyrin domain family, member F | -0.0562291 |
| PTMA | prothymosin, alpha | -0.0550273 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0522709 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.0519496 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0505929 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.0504783 |
| FAM13A | family with sequence similarity 13, member A | -0.0491952 |
| LMAN1 | lectin, mannose-binding, 1 | -0.047929 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0476628 |
| RBM39 | RNA binding motif protein 39 | -0.0462558 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0461235 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0448287 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.044544 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0443171 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0430151 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0428708 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0426051 |
| VEGFA | vascular endothelial growth factor A | -0.0424752 |
| B2M | beta-2-microglobulin | -0.0410782 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0402733 |
| NOP58 | NOP58 ribonucleoprotein | -0.0397609 |
| COL1A2 | collagen, type I, alpha 2 | -0.0396249 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0388868 |
| HLA-C | major histocompatibility complex, class I, C | -0.0385426 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | -0.0381396 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0378198 |
| TMEM165 | transmembrane protein 165 | -0.0374863 |
| PGK1 | phosphoglycerate kinase 1 | -0.0372356 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0364169 |
| WDR43 | WD repeat domain 43 | -0.0360297 |
| MMP12 | matrix metallopeptidase 12 | -0.0355389 |
| HM13 | histocompatibility (minor) 13 | -0.0354277 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0346288 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0344014 |
| CALU | calumenin | -0.033437 |
| SRP54 | signal recognition particle 54kDa | -0.0330109 |
| S100A6 | S100 calcium binding protein A6 | -0.0321825 |
| RPS6 | ribosomal protein S6 | -0.0316338 |
| CADM1 | cell adhesion molecule 1 | -0.0311365 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0311167 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0304751 |
| EGFR | epidermal growth factor receptor | -0.0299856 |
| GOLGA4 | golgin A4 | -0.0294608 |
| SBF2 | SET binding factor 2 | -0.0290332 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0288028 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | -0.0286125 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0285214 |
| RRBP1 | ribosome binding protein 1 | -0.0283462 |
| CDH13 | cadherin 13 | -0.0282483 |
| DDIT4 | DNA-damage-inducible transcript 4 | -0.0282233 |
| OSBPL9 | oxysterol binding protein-like 9 | -0.0278631 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0272901 |
| FOSL1 | FOS-like antigen 1 | -0.0272601 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0272507 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0269706 |
| COG5 | component of oligomeric golgi complex 5 | -0.0268539 |
| TPM1 | tropomyosin 1 (alpha) | -0.0267398 |
| SRRM1 | serine/arginine repetitive matrix 1 | -0.0265097 |
| UBC | ubiquitin C | -0.0265086 |
| SETD5 | SET domain containing 5 | -0.0264039 |
| KAZN | kazrin, periplakin interacting protein | -0.0263993 |
| ACTG1 | actin gamma 1 | -0.0261659 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | -0.0258718 |
| S100A10 | S100 calcium binding protein A10 | -0.0258563 |
| KDM7A | lysine (K)-specific demethylase 7A | -0.0258373 |
| CDK13 | cyclin-dependent kinase 13 | -0.0257714 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | -0.0257268 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0257132 |
| MORF4L2 | mortality factor 4 like 2 | -0.0256119 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0255757 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0249834 |
| KDELR2 | KDEL (Lys-Asp-Glu-Leu) endoplasmic reticulum protein retention receptor 2 | -0.0249185 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0247865 |
| TMF1 | TATA element modulatory factor 1 | -0.0245819 |
| CSNK1A1 | casein kinase 1, alpha 1 | -0.024559 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0242915 |
| LSAMP | limbic system-associated membrane protein | -0.0242677 |
| COL5A1 | collagen, type V, alpha 1 | -0.0242019 |
| INSIG2 | insulin induced gene 2 | -0.0241311 |
| CBX3 | chromobox homolog 3 | -0.0239023 |
| HLA-A | major histocompatibility complex, class I, A | -0.0235128 |
| MT2A | metallothionein 2A | -0.0234002 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0233608 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | -0.0231135 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0225886 |
