| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.103238 |
| ANGPTL4 | angiopoietin-like 4 | 0.0909287 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0900136 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0805687 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.073966 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0728459 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0721445 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0697071 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0682428 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0673011 |
| PRKCA | protein kinase C, alpha | 0.0557813 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0533184 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0522021 |
| FMNL2 | formin-like 2 | 0.0512801 |
| SMAD3 | SMAD family member 3 | 0.0512188 |
| ANXA1 | annexin A1 | 0.0485397 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0477314 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0475444 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0475178 |
| ERBIN | erbb2 interacting protein | 0.0441871 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0441261 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0430768 |
| FLNA | filamin A, alpha | 0.0403584 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0403104 |
| FLNB | filamin B, beta | 0.0397853 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0393044 |
| NIBAN2 | niban apoptosis regulator 2 | 0.0392078 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0379805 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0378881 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0373369 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0369772 |
| YBX3 | Y box binding protein 3 | 0.0364735 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0360476 |
| MSN | moesin | 0.035704 |
| CPNE1 | copine I | 0.0352675 |
| TPI1 | triosephosphate isomerase 1 | 0.0351769 |
| CAPRIN2 | caprin family member 2 | 0.0344628 |
| SET | SET nuclear proto-oncogene | 0.0343138 |
| UTRN | utrophin | 0.0341189 |
| ITGA6 | integrin, alpha 6 | 0.0341091 |
| MYOF | myoferlin | 0.0340592 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0339819 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0337016 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0335489 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0333207 |
| ACTN1 | actinin, alpha 1 | 0.0329082 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0325998 |
| APP | amyloid beta (A4) precursor protein | 0.0325172 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0324817 |
| AHNAK | AHNAK nucleoprotein | 0.0322531 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.032038 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0319854 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0317395 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0317106 |
| AREG | amphiregulin | 0.0315595 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0315175 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0314362 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0310966 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0305307 |
| CEP250 | centrosomal protein 250kDa | 0.0302651 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0302211 |
| RPL26 | ribosomal protein L26 | 0.0300509 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0298884 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0298706 |
| INTS6 | integrator complex subunit 6 | 0.0296603 |
| FN1 | fibronectin 1 | 0.0292833 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0292642 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0291862 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0287183 |
| TJP1 | tight junction protein 1 | 0.028717 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0280979 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0280194 |
| AFDN | afadin, adherens junction formation factor | 0.0279015 |
| KCMF1 | potassium channel modulatory factor 1 | 0.0271554 |
| RAI14 | retinoic acid induced 14 | 0.027035 |
| G3BP2 | GTPase activating protein (SH3 domain) binding protein 2 | 0.0265594 |
| EEA1 | early endosome antigen 1 | 0.0263786 |
| ATP13A3 | ATPase type 13A3 | 0.0263711 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0263449 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | 0.0259758 |
| HYOU1 | hypoxia up-regulated 1 | 0.0257999 |
| SLC35F2 | solute carrier family 35, member F2 | 0.0257941 |
| SNX9 | sorting nexin 9 | 0.0257446 |
| SETD5 | SET domain containing 5 | 0.0257005 |
| YAP1 | Yes-associated protein 1 | 0.0256633 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.025638 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0254152 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | 0.0252691 |
| TMSB10 | thymosin beta 10 | 0.0251788 |
| MYO9B | myosin IXB | 0.025107 |
| PLEC | plectin | 0.0250717 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.024834 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0243129 |
| DIAPH1 | diaphanous-related formin 1 | 0.0241365 |
| CEP170 | centrosomal protein 170kDa | 0.0239036 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0238402 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0237856 |
| OXSR1 | oxidative stress responsive 1 | 0.0234132 |
| COL5A1 | collagen, type V, alpha 1 | 0.0233399 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0231866 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TAS2R14 | taste receptor, type 2, member 14 | -0.0843449 |
| GOLGA4 | golgin A4 | -0.0829975 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0801476 |
| PTMA | prothymosin, alpha | -0.0719623 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0716914 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0632919 |
| RIGI | RNA sensor RIG-I | -0.062754 |
| IGF2 | insulin-like growth factor 2 | -0.054913 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0537216 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | -0.0476366 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0469055 |
| ZNF292 | zinc finger protein 292 | -0.0466983 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0466316 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0464353 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.045004 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0443005 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0442906 |
| DIAPH3 | diaphanous-related formin 3 | -0.0438787 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0423865 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0400328 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0392929 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0385291 |
| PRELID2 | PRELI domain containing 2 | -0.0381083 |
| PKM | pyruvate kinase, muscle | -0.0373335 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0369277 |
| MTREX | Mtr4 exosome RNA helicase | -0.0368274 |
| MKI67 | marker of proliferation Ki-67 | -0.0353409 |
| HDAC9 | histone deacetylase 9 | -0.034823 |
| FNIP1 | folliculin interacting protein 1 | -0.0347989 |
| CENPP | centromere protein P | -0.0338769 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0338097 |
| RBM39 | RNA binding motif protein 39 | -0.033428 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0330846 |
| DNER | delta/notch-like EGF repeat containing | -0.0327034 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0323099 |
| EGR1 | early growth response 1 | -0.0321761 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0313918 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0312927 |
| CD44 | CD44 molecule (Indian blood group) | -0.0305535 |
| CUL5 | cullin 5 | -0.0305485 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | -0.0305102 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.030266 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0298415 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0296556 |
| NUP214 | nucleoporin 214kDa | -0.0293559 |
| LRRC49 | leucine rich repeat containing 49 | -0.0288284 |
| WWOX | WW domain containing oxidoreductase | -0.0282398 |
| AHCTF1 | AT hook containing transcription factor 1 | -0.0282324 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | -0.0281829 |
| AFF4 | AF4/FMR2 family, member 4 | -0.0281411 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.0281339 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0280623 |
| KIF2A | kinesin heavy chain member 2A | -0.0280491 |
| TCERG1 | transcription elongation regulator 1 | -0.0277826 |
| FOXO3 | forkhead box O3 | -0.0277172 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0276222 |
| NBEA | neurobeachin | -0.0275595 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0275269 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0273512 |
| RPS25 | ribosomal protein S25 | -0.027317 |
| MAP1B | microtubule-associated protein 1B | -0.0273013 |
| RSF1 | remodeling and spacing factor 1 | -0.026941 |
| ZNF609 | zinc finger protein 609 | -0.0268606 |
| YEATS2 | YEATS domain containing 2 | -0.0267608 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0266876 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.026604 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | -0.0263363 |
| LARP1 | La ribonucleoprotein domain family, member 1 | -0.0258494 |
| NCOA1 | nuclear receptor coactivator 1 | -0.0256164 |
| AVL9 | AVL9 homolog (S. cerevisiase) | -0.0255601 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0254871 |
| DPYD | dihydropyrimidine dehydrogenase | -0.025472 |
| NUCB2 | nucleobindin 2 | -0.025311 |
| NKTR | natural killer cell triggering receptor | -0.025214 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0250246 |
| ZBTB10 | zinc finger and BTB domain containing 10 | -0.0249114 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | -0.0245448 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0244009 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0243834 |
| GGNBP2 | gametogenetin binding protein 2 | -0.0240891 |
| TPM4 | tropomyosin 4 | -0.0239676 |
| ECT2 | epithelial cell transforming 2 | -0.0235857 |
| AEBP2 | AE binding protein 2 | -0.023552 |
| ZBTB35 | zinc finger and BTB domain containing 35 | -0.023411 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.023244 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.0232026 |
| ATF7IP | activating transcription factor 7 interacting protein | -0.0231198 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | -0.0231018 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0229921 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.0229054 |
| AK1 | adenylate kinase 1 | -0.022871 |
| NBAS | neuroblastoma amplified sequence | -0.0228349 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0227945 |
| ANKRD17 | ankyrin repeat domain 17 | -0.0227009 |
| BRD8 | bromodomain containing 8 | -0.0224907 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | -0.0223754 |
| WTAP | Wilms tumor 1 associated protein | -0.0220215 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0220053 |
| ZNF438 | zinc finger protein 438 | -0.0220039 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0219523 |
