| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darinaparsin perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darinaparsin_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.185908 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.129774 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.115794 |
| PTMA | prothymosin, alpha | 0.110644 |
| ENO1 | enolase 1, (alpha) | 0.0833284 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0807934 |
| ASPH | aspartate beta-hydroxylase | 0.0787737 |
| VIM | vimentin | 0.0728365 |
| PLIN2 | perilipin 2 | 0.0724327 |
| FTL | ferritin, light polypeptide | 0.068041 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.061074 |
| TMSB10 | thymosin beta 10 | 0.0607484 |
| MT2A | metallothionein 2A | 0.0596732 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0578508 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0554295 |
| RPL37A | ribosomal protein L37a | 0.052229 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.051853 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0504828 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0498338 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.046009 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0456133 |
| RPS12 | ribosomal protein S12 | 0.0442097 |
| NDRG1 | N-myc downstream regulated 1 | 0.0426443 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0410782 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0406331 |
| RPS8 | ribosomal protein S8 | 0.0366524 |
| RPL26 | ribosomal protein L26 | 0.0358962 |
| ANGPTL4 | angiopoietin-like 4 | 0.0355683 |
| STC2 | stanniocalcin 2 | 0.0353792 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0340981 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0337093 |
| ACTG1 | actin gamma 1 | 0.0336774 |
| IFI27 | interferon, alpha-inducible protein 27 | 0.0327256 |
| RPL9 | ribosomal protein L9 | 0.0307672 |
| RPS6 | ribosomal protein S6 | 0.0304085 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.029401 |
| B2M | beta-2-microglobulin | 0.0291015 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0283192 |
| RPL31 | ribosomal protein L31 | 0.0281568 |
| RPS3 | ribosomal protein S3 | 0.0279661 |
| EGFR | epidermal growth factor receptor | 0.0276434 |
| RACK1 | receptor for activated C kinase 1 | 0.0274506 |
| PLEC | plectin | 0.0270985 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0268473 |
| S100A9 | S100 calcium binding protein A9 | 0.0268441 |
| HSPA1A | heat shock 70kDa protein 1A | 0.0264846 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0256377 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0253734 |
| DUSP6 | dual specificity phosphatase 6 | 0.0252217 |
| HIPK2 | homeodomain interacting protein kinase 2 | 0.0250743 |
| HYOU1 | hypoxia up-regulated 1 | 0.0249138 |
| RPS27 | ribosomal protein S27 | 0.0245322 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0244165 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0243784 |
| S100A6 | S100 calcium binding protein A6 | 0.0242635 |
| TPM3 | tropomyosin 3 | 0.0242486 |
| SOX4 | SRY (sex determining region Y)-box 4 | 0.0237985 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0234859 |
| RAD51B | RAD51 paralog B | 0.023303 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0232875 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0232865 |
| HM13 | histocompatibility (minor) 13 | 0.0232102 |
| STC1 | stanniocalcin 1 | 0.0228963 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0228786 |
| POTEF | POTE ankyrin domain family, member F | 0.022717 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0226634 |
| DNAJB1 | DnaJ (Hsp40) homolog, subfamily B, member 1 | 0.0224773 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | 0.0223627 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0222922 |
| LAMB3 | laminin, beta 3 | 0.0222509 |
| FLNB | filamin B, beta | 0.0222395 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0221634 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0217477 |
| VEGFA | vascular endothelial growth factor A | 0.0217278 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0215025 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.0212693 |
| CALR | calreticulin | 0.0212598 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0209437 |
| TPI1 | triosephosphate isomerase 1 | 0.020742 |
| RPS19 | ribosomal protein S19 | 0.0207284 |
| IFI16 | interferon, gamma-inducible protein 16 | 0.0205646 |
| MCL1 | myeloid cell leukemia 1 | 0.0205556 |
| LMO7 | LIM domain 7 | 0.0203392 |
| RPS27A | ribosomal protein S27a | 0.0201718 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0201203 |
| BRD2 | bromodomain containing 2 | 0.0198709 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.019678 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0196619 |
| RPL37 | ribosomal protein L37 | 0.0195784 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.019199 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0191653 |
| PALLD | palladin, cytoskeletal associated protein | 0.019161 |
| EIF5B | eukaryotic translation initiation factor 5B | 0.0186229 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0180734 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0180398 |
| MTDH | metadherin | 0.0180138 |
| GOLGB1 | golgin B1 | 0.0179313 |
| RPLP2 | ribosomal protein, large, P2 | 0.0177814 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.017728 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.017669 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.203939 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.182024 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.138375 |
| NRG1 | neuregulin 1 | -0.110832 |
| FN1 | fibronectin 1 | -0.105659 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.100819 |
| GLIS3 | GLIS family zinc finger 3 | -0.0866656 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0781083 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.06702 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0639077 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0594256 |
| RBM39 | RNA binding motif protein 39 | -0.0521412 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0496663 |
| RUNX2 | runt-related transcription factor 2 | -0.0474181 |
| DENND5B | DENN/MADD domain containing 5B | -0.0469607 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0458091 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0440137 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | -0.043946 |
| AHR | aryl hydrocarbon receptor | -0.0415882 |
| SYT1 | synaptotagmin I | -0.0411138 |
| TMEM156 | transmembrane protein 156 | -0.0394626 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.0393694 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.037569 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0363118 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0359713 |
| YBX3 | Y box binding protein 3 | -0.0355127 |
| OGA | O-GlcNAcase | -0.0352478 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.035071 |
| HELZ | helicase with zinc finger | -0.0350644 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0342474 |
| QKI | QKI, KH domain containing, RNA binding | -0.0339105 |
| NEK7 | NIMA-related kinase 7 | -0.0336607 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0332112 |
| EWSR1 | EWS RNA-binding protein 1 | -0.0331827 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0328638 |
| TXNIP | thioredoxin interacting protein | -0.0321683 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0321614 |
| PTK2 | protein tyrosine kinase 2 | -0.0320187 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0320092 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0319446 |
| SPAG9 | sperm associated antigen 9 | -0.031772 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0313149 |
| ETNK1 | ethanolamine kinase 1 | -0.0310429 |
| AOPEP | aminopeptidase O (putative) | -0.0306417 |
| FNBP1 | formin binding protein 1 | -0.0304411 |
| RLF | rearranged L-myc fusion | -0.0304008 |
| RHEB | Ras homolog enriched in brain | -0.0302076 |
| RNF145 | ring finger protein 145 | -0.0299891 |
| GOLT1B | golgi transport 1B | -0.0298931 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0298833 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0298491 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | -0.0287866 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0287355 |
| USP3 | ubiquitin specific peptidase 3 | -0.0286764 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0285712 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0285121 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.028461 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0282846 |
| COPA | coatomer protein complex, subunit alpha | -0.0280199 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0279949 |
| MNAT1 | MNAT CDK-activating kinase assembly factor 1 | -0.0276176 |
| DPYD | dihydropyrimidine dehydrogenase | -0.027534 |
| MIS18BP1 | MIS18 binding protein 1 | -0.0273356 |
| WDR45B | WD repeat domain 45B | -0.0272562 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0269018 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0263998 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0261686 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0259202 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0258873 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0258815 |
| CDC73 | cell division cycle 73 | -0.0257526 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0254916 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | -0.025433 |
| BHLHE40 | basic helix-loop-helix family, member e40 | -0.0253681 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0253207 |
| TNS3 | tensin 3 | -0.0252428 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0250431 |
| ETV6 | ets variant 6 | -0.0247838 |
| OSMR | oncostatin M receptor | -0.0241714 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0240744 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0237239 |
| PARD3 | par-3 family cell polarity regulator | -0.0236853 |
| COG5 | component of oligomeric golgi complex 5 | -0.0236647 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0235639 |
| PELI1 | pellino E3 ubiquitin protein ligase 1 | -0.0234916 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0234644 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0231882 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0230336 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0228987 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0227654 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0227448 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0222252 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0221291 |
| TXNRD1 | thioredoxin reductase 1 | -0.0221286 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0219945 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | -0.0219148 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0219112 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0218528 |
| TFG | TRK-fused gene | -0.0218165 |
| NUP58 | nucleoporin 58 | -0.0217861 |
