| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | 0.218294 |
| MT2A | metallothionein 2A | 0.0755567 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0705007 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | 0.0640276 |
| B2M | beta-2-microglobulin | 0.0595063 |
| POTEF | POTE ankyrin domain family, member F | 0.0589267 |
| CSTB | cystatin B (stefin B) | 0.0486025 |
| S100A6 | S100 calcium binding protein A6 | 0.04612 |
| STC1 | stanniocalcin 1 | 0.0451917 |
| UBC | ubiquitin C | 0.0378706 |
| PTMA | prothymosin, alpha | 0.0342595 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03348 |
| FTL | ferritin, light polypeptide | 0.0333332 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.031989 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0319765 |
| OPTN | optineurin | 0.0303728 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0302897 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0301301 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0295762 |
| INSIG2 | insulin induced gene 2 | 0.0279685 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0279139 |
| ADM | adrenomedullin | 0.0272709 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | 0.0267198 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0257121 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0250235 |
| OGA | O-GlcNAcase | 0.0244944 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0236261 |
| WAC | WW domain containing adaptor with coiled-coil | 0.023246 |
| PCBP2 | poly(rC) binding protein 2 | 0.0227712 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0223279 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0214992 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0214089 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0210266 |
| ARF6 | ADP-ribosylation factor 6 | 0.0209106 |
| RPL12 | ribosomal protein L12 | 0.0207136 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.020713 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0207014 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0203957 |
| RBM25 | RNA binding motif protein 25 | 0.0202611 |
| CYLD | cylindromatosis (turban tumor syndrome) | 0.0201156 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0200575 |
| HDGF | hepatoma-derived growth factor | 0.0200321 |
| SETD5 | SET domain containing 5 | 0.0200086 |
| FAM107B | family with sequence similarity 107, member B | 0.0194811 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | 0.0193371 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0190551 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0189638 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0186883 |
| MSN | moesin | 0.0185849 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0184834 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0184276 |
| CENPF | centromere protein F, 350/400kDa | 0.0184151 |
| VDAC1 | voltage-dependent anion channel 1 | 0.0180995 |
| CDK18 | cyclin-dependent kinase 18 | 0.0179907 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0178477 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.017663 |
| EZR | ezrin | 0.0175307 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0174375 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0173099 |
| RAI1 | retinoic acid induced 1 | 0.017239 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0171199 |
| ATP2C1 | ATPase, Ca++ transporting, type 2C, member 1 | 0.0168129 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0163207 |
| ARRDC3 | arrestin domain containing 3 | 0.0161058 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0159953 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.015914 |
| HMGB2 | high mobility group box 2 | 0.0156258 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0152943 |
| RAB18 | RAB18, member RAS oncogene family | 0.0152899 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0152153 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0151946 |
| PTMS | parathymosin | 0.0150544 |
| DSPP | dentin sialophosphoprotein | 0.0150088 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0149302 |
| CCNL1 | cyclin L1 | 0.0148572 |
| GPX4 | glutathione peroxidase 4 | 0.0147211 |
| CALR | calreticulin | 0.0146659 |
| MCFD2 | multiple coagulation factor deficiency 2 | 0.0146616 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | 0.0144861 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | 0.0143674 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0143205 |
| RPS6 | ribosomal protein S6 | 0.014102 |
| PDCD4 | programmed cell death 4 (neoplastic transformation inhibitor) | 0.0140439 |
| PDXK | pyridoxal (pyridoxine, vitamin B6) kinase | 0.014035 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0139507 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0137658 |
| CNOT8 | CCR4-NOT transcription complex, subunit 8 | 0.0136693 |
| HELZ | helicase with zinc finger | 0.013628 |
| NGLY1 | N-glycanase 1 | 0.0134155 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0133142 |
| SERINC3 | serine incorporator 3 | 0.0132211 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0131935 |
| EXOC1 | exocyst complex component 1 | 0.0129966 |
| WDFY1 | WD repeat and FYVE domain containing 1 | 0.012904 |
| PABPN1 | poly(A) binding protein, nuclear 1 | 0.0128953 |
| RPS12 | ribosomal protein S12 | 0.0128583 |
| MMP12 | matrix metallopeptidase 12 | 0.0128217 |
| MYADM | myeloid-associated differentiation marker | 0.0127929 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0127344 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0126938 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.162198 |
| PODXL | podocalyxin-like | -0.15455 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.15142 |
| NAV1 | neuron navigator 1 | -0.129188 |
| AHNAK | AHNAK nucleoprotein | -0.123086 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.116429 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.112844 |
| COL5A1 | collagen, type V, alpha 1 | -0.10947 |
| CD44 | CD44 molecule (Indian blood group) | -0.0978814 |
| MAP1B | microtubule-associated protein 1B | -0.0969993 |
| THBS2 | thrombospondin 2 | -0.077657 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0731887 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0689236 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0687942 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0685287 |
| CDH13 | cadherin 13 | -0.0639901 |
| MX2 | MX dynamin-like GTPase 2 | -0.0626289 |
| GLIS3 | GLIS family zinc finger 3 | -0.0613997 |
| COL5A2 | collagen, type V, alpha 2 | -0.0586593 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0517876 |
| RUNX1 | runt-related transcription factor 1 | -0.0517219 |
| SEPTIN9 | septin 9 | -0.0512195 |
| FBN1 | fibrillin 1 | -0.0511914 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | -0.0509866 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0500404 |
| AUTS2 | autism susceptibility candidate 2 | -0.0492854 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0489636 |
| CCND1 | cyclin D1 | -0.0474022 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0467232 |
| FLNA | filamin A, alpha | -0.0458206 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0452956 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.045184 |
| LOXL2 | lysyl oxidase-like 2 | -0.0449294 |
| LOX | lysyl oxidase | -0.0440289 |
| RNF213 | ring finger protein 213 | -0.0424778 |
| RIGI | RNA sensor RIG-I | -0.0419938 |
| COL1A2 | collagen, type I, alpha 2 | -0.0419921 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0414741 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0410022 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0404565 |
| FSTL1 | follistatin-like 1 | -0.0403881 |
| HS3ST3A1 | heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1 | -0.0401878 |
| RRBP1 | ribosome binding protein 1 | -0.0397957 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0388389 |
| COL3A1 | collagen, type III, alpha 1 | -0.0387114 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0385259 |
| PRELID2 | PRELI domain containing 2 | -0.0376575 |
| MEIS2 | Meis homeobox 2 | -0.0363619 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0358255 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0357522 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0340715 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | -0.0333697 |
| PARD3 | par-3 family cell polarity regulator | -0.0333204 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0329229 |
| HLA-C | major histocompatibility complex, class I, C | -0.0321819 |
| SAMD9L | sterile alpha motif domain containing 9-like | -0.0321512 |
| PXDN | peroxidasin | -0.031786 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | -0.0317436 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0317318 |
| TENM3 | teneurin transmembrane protein 3 | -0.0316947 |
| SMYD3 | SET and MYND domain containing 3 | -0.0316537 |
| COL4A2 | collagen, type IV, alpha 2 | -0.0316533 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0314875 |
| EGFR | epidermal growth factor receptor | -0.0313662 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0311805 |
| EFNA5 | ephrin-A5 | -0.0311143 |
| OSMR | oncostatin M receptor | -0.0311017 |
| SLC39A11 | solute carrier family 39, member 11 | -0.0309577 |
| CDK6 | cyclin-dependent kinase 6 | -0.0307245 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0305404 |
| MB21D2 | Mab-21 domain containing 2 | -0.03041 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0303881 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0301671 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0301519 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.029835 |
| TPM1 | tropomyosin 1 (alpha) | -0.0296204 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.029044 |
| FRMD4A | FERM domain containing 4A | -0.0284684 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0284649 |
| APP | amyloid beta (A4) precursor protein | -0.0282727 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0281613 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.028129 |
| ZNF217 | zinc finger protein 217 | -0.0281149 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0279926 |
| ADAR | adenosine deaminase, RNA-specific | -0.0272055 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0269737 |
| CANX | calnexin | -0.0267988 |
| PLXNA2 | plexin A2 | -0.0267955 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0267713 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0265184 |
| HDLBP | high density lipoprotein binding protein | -0.0264734 |
| FN1 | fibronectin 1 | -0.0264085 |
| TUBB | tubulin, beta class I | -0.0262815 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0262747 |
| RAI14 | retinoic acid induced 14 | -0.0262381 |
| ACTG1 | actin gamma 1 | -0.0260723 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0259903 |
| RRM2 | ribonucleotide reductase M2 | -0.0257809 |
| ANTXR1 | anthrax toxin receptor 1 | -0.0257509 |
| CD99 | CD99 molecule | -0.0256864 |
