| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.16848 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0841672 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0741628 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.056563 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.0529254 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0481282 |
| CANX | calnexin | 0.0444025 |
| NDRG1 | N-myc downstream regulated 1 | 0.0412814 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0401228 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0366083 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0356143 |
| CALR | calreticulin | 0.0353449 |
| GOLGB1 | golgin B1 | 0.0332658 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.0331383 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0330947 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.032846 |
| COG6 | component of oligomeric golgi complex 6 | 0.0328147 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0325779 |
| SEC24D | SEC24 family member D | 0.0309863 |
| CALU | calumenin | 0.0307523 |
| HDLBP | high density lipoprotein binding protein | 0.0293576 |
| SUCO | SUN domain containing ossification factor | 0.0281689 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0279548 |
| MORF4L2 | mortality factor 4 like 2 | 0.0278439 |
| GOLGA2 | golgin A2 | 0.026696 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0259283 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0255995 |
| LMO7 | LIM domain 7 | 0.0255673 |
| GOLGA4 | golgin A4 | 0.0252156 |
| AGR2 | anterior gradient 2 | 0.0245904 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0243679 |
| PDXDC1 | pyridoxal-dependent decarboxylase domain containing 1 | 0.0243304 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0239584 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0238305 |
| COPA | coatomer protein complex, subunit alpha | 0.0237958 |
| SEC24A | SEC24 family member A | 0.0236701 |
| NUCB2 | nucleobindin 2 | 0.0236015 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.02327 |
| TMEM263 | transmembrane protein 263 | 0.0229643 |
| IRF1 | interferon regulatory factor 1 | 0.0226297 |
| COPB1 | coatomer protein complex, subunit beta 1 | 0.0226007 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0224603 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0221581 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0220457 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0219757 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0216098 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0212169 |
| UGDH | UDP-glucose 6-dehydrogenase | 0.0211061 |
| ADM | adrenomedullin | 0.0207633 |
| HM13 | histocompatibility (minor) 13 | 0.0207025 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0206146 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0200298 |
| DSTN | destrin (actin depolymerizing factor) | 0.0197364 |
| SERP1 | stress-associated endoplasmic reticulum protein 1 | 0.0195244 |
| SRP54 | signal recognition particle 54kDa | 0.0194241 |
| TM9SF2 | transmembrane 9 superfamily member 2 | 0.0194212 |
| MLEC | malectin | 0.0193722 |
| ZNF841 | zinc finger protein 841 | 0.0190697 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0187662 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0186958 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.0184206 |
| TMF1 | TATA element modulatory factor 1 | 0.0183133 |
| ARF4 | ADP-ribosylation factor 4 | 0.018226 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0180771 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | 0.0176018 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0175271 |
| UBC | ubiquitin C | 0.0173927 |
| DIS3 | DIS3 exosome endoribonuclease and 3'-5' exoribonuclease | 0.017306 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0172905 |
| SSR1 | signal sequence receptor, alpha | 0.0172823 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | 0.0170913 |
| PGM3 | phosphoglucomutase 3 | 0.0170661 |
| OGA | O-GlcNAcase | 0.0170387 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.01699 |
| CCDC186 | coiled-coil domain containing 186 | 0.016978 |
| HYOU1 | hypoxia up-regulated 1 | 0.0168999 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0168145 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0167651 |
| MBOAT2 | membrane bound O-acyltransferase domain containing 2 | 0.016698 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0166855 |
| SEC61A1 | Sec61 alpha 1 subunit (S. cerevisiae) | 0.016542 |
| HERPUD1 | homocysteine-inducible, endoplasmic reticulum stress-inducible, ubiquitin-like domain member 1 | 0.0164383 |
| AHI1 | Abelson helper integration site 1 | 0.0164281 |
| PCBP2 | poly(rC) binding protein 2 | 0.016338 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | 0.0161515 |
| PMM2 | phosphomannomutase 2 | 0.0160526 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.01599 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0159308 |
| SMIM14 | small integral membrane protein 14 | 0.015915 |
| CENPF | centromere protein F, 350/400kDa | 0.0158282 |
| RNF149 | ring finger protein 149 | 0.015697 |
| CDHR2 | cadherin-related family member 2 | 0.0155006 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0154991 |
| GOLGA3 | golgin A3 | 0.0153644 |
| DSPP | dentin sialophosphoprotein | 0.0151337 |
| SEC63 | SEC63 homolog (S. cerevisiae) | 0.0151108 |
| RAB2A | RAB2A, member RAS oncogene family | 0.0149523 |
| SCFD1 | sec1 family domain containing 1 | 0.0148346 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0148107 |
| SEL1L | sel-1 suppressor of lin-12-like (C. elegans) | 0.0147872 |
| Symbol | Name | Standardized Value |
|---|---|---|
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.218469 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.125982 |
| RNF213 | ring finger protein 213 | -0.112141 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.108074 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.106455 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.103449 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0923907 |
| XAF1 | XIAP associated factor 1 | -0.0883416 |
| RIGI | RNA sensor RIG-I | -0.0882326 |
| PRKCA | protein kinase C, alpha | -0.0872199 |
| LYZ | lysozyme | -0.0868095 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0867914 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0866891 |
| MX1 | MX dynamin-like GTPase 1 | -0.0804509 |
| MSI2 | musashi RNA-binding protein 2 | -0.079828 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0785522 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0759101 |
| MX2 | MX dynamin-like GTPase 2 | -0.0756102 |
| SP100 | SP100 nuclear antigen | -0.0705004 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0655007 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | -0.0640909 |
| ITGA6 | integrin, alpha 6 | -0.0634397 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0618233 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0611351 |
| ATP11A | ATPase, class VI, type 11A | -0.0594897 |
| PLSCR1 | phospholipid scramblase 1 | -0.0587424 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0585309 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0579511 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0572463 |
| EPHB2 | EPH receptor B2 | -0.0570037 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0557426 |
| ATP10B | ATPase, class V, type 10B | -0.055603 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0552562 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0536144 |
| NPSR1 | neuropeptide S receptor 1 | -0.0535881 |
| SPATA13 | spermatogenesis associated 13 | -0.0527164 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.05194 |
| TRERF1 | transcriptional regulating factor 1 | -0.0502923 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0494768 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0494642 |
| ETV6 | ets variant 6 | -0.0488288 |
| SSH2 | slingshot protein phosphatase 2 | -0.04824 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0482262 |
| EXT1 | exostosin glycosyltransferase 1 | -0.047533 |
| ERBIN | erbb2 interacting protein | -0.0470888 |
| VCL | vinculin | -0.0463933 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0462945 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0460773 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0460733 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0453066 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0448695 |
| LCN2 | lipocalin 2 | -0.0430904 |
| TMC5 | transmembrane channel-like 5 | -0.0414797 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.0414156 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.041241 |
| DGKH | diacylglycerol kinase, eta | -0.0398167 |
| FMN1 | formin 1 | -0.0392914 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0391257 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.039114 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0384458 |
| MAP7 | microtubule-associated protein 7 | -0.0380459 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0373512 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0368444 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0366376 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.0359587 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0358066 |
| NCKAP5 | NCK-associated protein 5 | -0.0355828 |
| ANKRD10 | ankyrin repeat domain 10 | -0.03496 |
| MUC13 | mucin 13, cell surface associated | -0.0345684 |
| PTGR1 | prostaglandin reductase 1 | -0.0341259 |
| PMP22 | peripheral myelin protein 22 | -0.0340992 |
| RAD51B | RAD51 paralog B | -0.0340119 |
| DOCK1 | dedicator of cytokinesis 1 | -0.0339839 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0337298 |
| MCU | mitochondrial calcium uniporter | -0.0331301 |
| PRKCE | protein kinase C, epsilon | -0.0330396 |
| BCL2L1 | BCL2-like 1 | -0.0329616 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0329201 |
| LAMA4 | laminin, alpha 4 | -0.032668 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0326211 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0325741 |
| IGF1R | insulin-like growth factor 1 receptor | -0.0325117 |
| MACC1 | metastasis associated in colon cancer 1 | -0.0324037 |
| CUX1 | cut-like homeobox 1 | -0.0323654 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0320467 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0319962 |
| TNFSF10 | tumor necrosis factor (ligand) superfamily, member 10 | -0.0318302 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.03156 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.0313063 |
| RUNX1 | runt-related transcription factor 1 | -0.031223 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | -0.0311764 |
| CMPK1 | cytidine monophosphate (UMP-CMP) kinase 1, cytosolic | -0.0309355 |
| BICRAL | BICRA like chromatin remodeling complex associated protein | -0.0308066 |
| NF1 | neurofibromin 1 | -0.0306544 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0302323 |
| FOXP1 | forkhead box P1 | -0.0299606 |
| JUN | jun proto-oncogene | -0.029663 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0294897 |
| OAS3 | 2'-5'-oligoadenylate synthetase 3, 100kDa | -0.0294133 |
| MECOM | MDS1 and EVI1 complex locus | -0.0292372 |
