| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in LS 180 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_LS 180 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EZR | ezrin | 0.145583 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.125 |
| TXNIP | thioredoxin interacting protein | 0.115015 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.111289 |
| LDHA | lactate dehydrogenase A | 0.0926737 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0919771 |
| DSPP | dentin sialophosphoprotein | 0.0841536 |
| LMO7 | LIM domain 7 | 0.0809962 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.076811 |
| PGK1 | phosphoglycerate kinase 1 | 0.0737159 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0722389 |
| FAM13A | family with sequence similarity 13, member A | 0.0664552 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0642269 |
| GOLGA4 | golgin A4 | 0.0641636 |
| PTMA | prothymosin, alpha | 0.0632523 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0613931 |
| ENO1 | enolase 1, (alpha) | 0.0606816 |
| PCBP2 | poly(rC) binding protein 2 | 0.0606394 |
| KIF5B | kinesin family member 5B | 0.0604929 |
| ANXA1 | annexin A1 | 0.0591943 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0587088 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0585871 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0583604 |
| ITGA6 | integrin, alpha 6 | 0.0563944 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0561619 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0558914 |
| MLEC | malectin | 0.0558011 |
| RBM39 | RNA binding motif protein 39 | 0.0556885 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | 0.05483 |
| RNF145 | ring finger protein 145 | 0.0539138 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0527198 |
| EREG | epiregulin | 0.0525808 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0525568 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0523373 |
| FAT1 | FAT atypical cadherin 1 | 0.0517735 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.051396 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0503267 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0502166 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0501274 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0487736 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0466411 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0464915 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0455354 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0446647 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0442025 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.044067 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0429985 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0426795 |
| CALR | calreticulin | 0.0419967 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0416894 |
| VEGFA | vascular endothelial growth factor A | 0.0415052 |
| TPD52 | tumor protein D52 | 0.041322 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0410608 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0400798 |
| WAC | WW domain containing adaptor with coiled-coil | 0.039778 |
| ZNF292 | zinc finger protein 292 | 0.0394467 |
| WDR45B | WD repeat domain 45B | 0.0391424 |
| OGA | O-GlcNAcase | 0.0384472 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0384224 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0380372 |
| EMP1 | epithelial membrane protein 1 | 0.037784 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0376547 |
| AREG | amphiregulin | 0.037619 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0364286 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0364056 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0364004 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0363614 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0363472 |
| EPCAM | epithelial cell adhesion molecule | 0.0363109 |
| MED13L | mediator complex subunit 13-like | 0.0362107 |
| CLCN3 | chloride channel, voltage-sensitive 3 | 0.0360959 |
| GDF15 | growth differentiation factor 15 | 0.0360721 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0359484 |
| CCNY | cyclin Y | 0.0358711 |
| MED13 | mediator complex subunit 13 | 0.0358666 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.0356601 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0354359 |
| RAD21 | RAD21 homolog (S. pombe) | 0.035428 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0353399 |
| ANXA2 | annexin A2 | 0.0351096 |
| TES | testin LIM domain protein | 0.0350922 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0349672 |
| MATR3 | matrin 3 | 0.0348049 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0342216 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0339159 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0339041 |
| ATF4 | activating transcription factor 4 | 0.0338489 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0337959 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0337887 |
| YTHDC1 | YTH domain containing 1 | 0.0337445 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0335959 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0330766 |
| RLF | rearranged L-myc fusion | 0.0329181 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0327462 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0324003 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0322075 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.031974 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0319594 |
| NCKAP1 | NCK-associated protein 1 | 0.0316181 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0315125 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.101767 |
| NPSR1 | neuropeptide S receptor 1 | -0.0932263 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0730324 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0704554 |
| ONECUT3 | one cut homeobox 3 | -0.0692942 |
| RPL35A | ribosomal protein L35a | -0.0642363 |
| VCL | vinculin | -0.0628985 |
| MUC5AC | mucin 5AC, oligomeric mucus/gel-forming | -0.0534105 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0502263 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0464865 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0463946 |
| TNS4 | tensin 4 | -0.0448398 |
| FHIT | fragile histidine triad | -0.0428986 |
| RPLP1 | ribosomal protein, large, P1 | -0.0389007 |
| ACTG1 | actin gamma 1 | -0.0379523 |
| RPL34 | ribosomal protein L34 | -0.0363269 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.035828 |
| RPL9 | ribosomal protein L9 | -0.0354247 |
| RAD51B | RAD51 paralog B | -0.035406 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.033672 |
| GRIN2B | glutamate receptor, ionotropic, N-methyl D-aspartate 2B | -0.0315502 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0307713 |
| IER3 | immediate early response 3 | -0.030017 |
| RPS8 | ribosomal protein S8 | -0.0285452 |
| AHNAK | AHNAK nucleoprotein | -0.0278055 |
| SAMD5 | sterile alpha motif domain containing 5 | -0.0277172 |
| TMSB10 | thymosin beta 10 | -0.0272527 |
| CCSER1 | coiled-coil serine-rich protein 1 | -0.0270802 |
| EGFR | epidermal growth factor receptor | -0.0261377 |
| FRMD5 | FERM domain containing 5 | -0.0257286 |
| MUC6 | mucin 6, oligomeric mucus/gel-forming | -0.0255912 |
| PRSS3 | protease, serine, 3 | -0.0255463 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0255195 |
| PALLD | palladin, cytoskeletal associated protein | -0.0246835 |
| CADPS | Ca++-dependent secretion activator | -0.0246101 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0244581 |
| SH3D19 | SH3 domain containing 19 | -0.0231546 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.023095 |
| RPS24 | ribosomal protein S24 | -0.0228956 |
| HMGB1 | high mobility group box 1 | -0.0227632 |
| RPS29 | ribosomal protein S29 | -0.0225634 |
| MYO1D | myosin ID | -0.0224416 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0222526 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0217549 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0216548 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0214479 |
| GPHN | gephyrin | -0.0212663 |
| MYO1E | myosin IE | -0.0208476 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0206422 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0205281 |
| TMEM45B | transmembrane protein 45B | -0.0204259 |
| TFF1 | trefoil factor 1 | -0.0201804 |
| RPS19 | ribosomal protein S19 | -0.0200522 |
| ITGB4 | integrin, beta 4 | -0.0199248 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0195754 |
| RPS21 | ribosomal protein S21 | -0.0195604 |
| SMYD3 | SET and MYND domain containing 3 | -0.0195088 |
| RPL27 | ribosomal protein L27 | -0.0194244 |
| MECOM | MDS1 and EVI1 complex locus | -0.0192954 |
| NRXN3 | neurexin 3 | -0.0191406 |
| RPL23 | ribosomal protein L23 | -0.0189689 |
| RPS27A | ribosomal protein S27a | -0.0189048 |
| RPL36 | ribosomal protein L36 | -0.0187499 |
| RPS25 | ribosomal protein S25 | -0.0186472 |
| UQCRB | ubiquinol-cytochrome c reductase binding protein | -0.0185459 |
| MGST1 | microsomal glutathione S-transferase 1 | -0.0182466 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0181158 |
| MUC17 | mucin 17, cell surface associated | -0.0180885 |
| RPLP2 | ribosomal protein, large, P2 | -0.0179595 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0177403 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0175561 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0175025 |
| ARHGAP6 | Rho GTPase activating protein 6 | -0.017294 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.0172282 |
| EXOC4 | exocyst complex component 4 | -0.0170549 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0169821 |
| MTAP | methylthioadenosine phosphorylase | -0.0169337 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.0168462 |
| VDR | vitamin D (1,25- dihydroxyvitamin D3) receptor | -0.0166887 |
| MUC5B | mucin 5B, oligomeric mucus/gel-forming | -0.0165959 |
| RPL31 | ribosomal protein L31 | -0.0163824 |
| RPS10 | ribosomal protein S10 | -0.0157076 |
| EGR1 | early growth response 1 | -0.0156067 |
| PTPRB | protein tyrosine phosphatase, receptor type, B | -0.0154924 |
| RAB10 | RAB10, member RAS oncogene family | -0.0154557 |
| ACTN4 | actinin, alpha 4 | -0.0154378 |
| RPL26 | ribosomal protein L26 | -0.0153068 |
| RPL37A | ribosomal protein L37a | -0.0152489 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0151987 |
| FOXP2 | forkhead box P2 | -0.0151021 |
| B4GALNT3 | beta-1,4-N-acetyl-galactosaminyl transferase 3 | -0.0150569 |
| ITPR2 | inositol 1,4,5-trisphosphate receptor, type 2 | -0.0150506 |
| RNF217 | ring finger protein 217 | -0.0149866 |
| DLGAP1 | discs, large (Drosophila) homolog-associated protein 1 | -0.0149695 |
| CCND1 | cyclin D1 | -0.0148791 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0148367 |
| TPM1 | tropomyosin 1 (alpha) | -0.0147123 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0146558 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0146405 |
| AHCYL2 | adenosylhomocysteinase-like 2 | -0.014539 |
