| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.107537 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0746114 |
| LMO7 | LIM domain 7 | 0.0601533 |
| EGFR | epidermal growth factor receptor | 0.0564758 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0504269 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0491313 |
| STC1 | stanniocalcin 1 | 0.0484285 |
| DSPP | dentin sialophosphoprotein | 0.0432044 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0416836 |
| LDHA | lactate dehydrogenase A | 0.0403316 |
| ASPH | aspartate beta-hydroxylase | 0.0380843 |
| ACTG1 | actin gamma 1 | 0.037725 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0370458 |
| SCEL | sciellin | 0.0346143 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | 0.0344256 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0337319 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.032672 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0314297 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.03069 |
| CPE | carboxypeptidase E | 0.0304311 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0270065 |
| POTEF | POTE ankyrin domain family, member F | 0.026991 |
| ANXA2 | annexin A2 | 0.0267612 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0267433 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0249585 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0230244 |
| LAMC2 | laminin, gamma 2 | 0.0227511 |
| IGFBP5 | insulin-like growth factor binding protein 5 | 0.0222466 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.02149 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | 0.0210083 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | 0.0199104 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0198988 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0196735 |
| TES | testin LIM domain protein | 0.0195232 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0192978 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0191205 |
| S100A10 | S100 calcium binding protein A10 | 0.0189633 |
| EZR | ezrin | 0.018795 |
| ANXA1 | annexin A1 | 0.0187493 |
| EFNA5 | ephrin-A5 | 0.0186938 |
| WASF2 | WAS protein family, member 2 | 0.0182253 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0182224 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0180915 |
| KRT18 | keratin 18, type I | 0.017346 |
| TPM4 | tropomyosin 4 | 0.0171768 |
| ENO1 | enolase 1, (alpha) | 0.0166453 |
| SDC4 | syndecan 4 | 0.0162789 |
| KIF5B | kinesin family member 5B | 0.016038 |
| RNF213 | ring finger protein 213 | 0.015921 |
| KRT7 | keratin 7, type II | 0.0156634 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0154718 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0153833 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0152971 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | 0.015271 |
| PERP | PERP, TP53 apoptosis effector | 0.0145981 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0145014 |
| FNBP1L | formin binding protein 1-like | 0.0144917 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0144916 |
| AHNAK | AHNAK nucleoprotein | 0.0143965 |
| SLK | STE20-like kinase | 0.0141978 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0140852 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | 0.0140185 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0138373 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0138167 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0137939 |
| DOCK9 | dedicator of cytokinesis 9 | 0.0136411 |
| FLNB | filamin B, beta | 0.0134642 |
| FAM13A | family with sequence similarity 13, member A | 0.01345 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | 0.0133722 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0132334 |
| RBM25 | RNA binding motif protein 25 | 0.0130812 |
| CPNE8 | copine VIII | 0.0129955 |
| ANGPTL4 | angiopoietin-like 4 | 0.0129108 |
| SLC38A2 | solute carrier family 38, member 2 | 0.012861 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0127157 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0126495 |
| KRT19 | keratin 19, type I | 0.0125476 |
| S100A6 | S100 calcium binding protein A6 | 0.0124593 |
| MAML3 | mastermind-like 3 (Drosophila) | 0.0124109 |
| CAP1 | CAP, adenylate cyclase-associated protein 1 (yeast) | 0.012406 |
| HECTD1 | HECT domain containing E3 ubiquitin protein ligase 1 | 0.012339 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0122251 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.012156 |
| PATJ | PATJ crumbs cell polarity complex component | 0.0121361 |
| MSN | moesin | 0.0120981 |
| CTBP2 | C-terminal binding protein 2 | 0.0119496 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0117982 |
| RAB27B | RAB27B, member RAS oncogene family | 0.0117617 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | 0.0117485 |
| LAMB3 | laminin, beta 3 | 0.0116125 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0115869 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0115853 |
| LAMA4 | laminin, alpha 4 | 0.0114865 |
| ARF6 | ADP-ribosylation factor 6 | 0.0114132 |
| CAV2 | caveolin 2 | 0.0112774 |
| CMIP | c-Maf inducing protein | 0.0111847 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0111245 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | 0.0111233 |
| LOC102724023 | ES1 protein homolog, mitochondrial | 0.0111068 |
| EHBP1 | EH domain binding protein 1 | 0.0109753 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.167059 |
| TXNRD1 | thioredoxin reductase 1 | -0.0809091 |
| MT2A | metallothionein 2A | -0.0778723 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0646928 |
| RUNX1 | runt-related transcription factor 1 | -0.0562828 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0515672 |
| AGO2 | argonaute RISC catalytic component 2 | -0.0512733 |
| RPLP1 | ribosomal protein, large, P1 | -0.0502563 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0467414 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0459653 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | -0.0445488 |
| TBC1D22A | TBC1 domain family, member 22A | -0.042486 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0416076 |
| SEC61G | Sec61 gamma subunit | -0.0406274 |
| RPL37A | ribosomal protein L37a | -0.0389484 |
| RPS3 | ribosomal protein S3 | -0.0377035 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0360942 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0345832 |
| RPS2 | ribosomal protein S2 | -0.0330302 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0324785 |
| CES1 | carboxylesterase 1 | -0.032188 |
| JMJD1C | jumonji domain containing 1C | -0.0321585 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.029056 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.0288988 |
| RPS6 | ribosomal protein S6 | -0.0286332 |
| FTL | ferritin, light polypeptide | -0.0278711 |
| DTNA | dystrobrevin, alpha | -0.0275323 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | -0.027482 |
| RPS8 | ribosomal protein S8 | -0.0274377 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0268363 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0256889 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | -0.0242273 |
| PNISR | PNN-interacting serine/arginine-rich protein | -0.0239287 |
| RPL7 | ribosomal protein L7 | -0.0238756 |
| GPATCH2L | G patch domain containing 2-like | -0.0236978 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0236402 |
| RPS25 | ribosomal protein S25 | -0.0229996 |
| USP53 | ubiquitin specific peptidase 53 | -0.0229212 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0227918 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0227276 |
| RPS12 | ribosomal protein S12 | -0.0224957 |
| NDRG1 | N-myc downstream regulated 1 | -0.022054 |
| RPL19 | ribosomal protein L19 | -0.0217657 |
| ZNF292 | zinc finger protein 292 | -0.0216871 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0216556 |
| RTN4 | reticulon 4 | -0.0215061 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0211972 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0209868 |
| RPS17 | ribosomal protein S17 | -0.0209009 |
| RPS27 | ribosomal protein S27 | -0.0208803 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | -0.0206266 |
| TMEM165 | transmembrane protein 165 | -0.0204549 |
| RPL34 | ribosomal protein L34 | -0.0203059 |
| RPLP2 | ribosomal protein, large, P2 | -0.0202217 |
| UVRAG | UV radiation resistance associated | -0.0200864 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0197745 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | -0.0197431 |
| RPS23 | ribosomal protein S23 | -0.0194313 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0193366 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0193131 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0191584 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.019042 |
| RAD51B | RAD51 paralog B | -0.0187778 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0187699 |
| RPL35A | ribosomal protein L35a | -0.0187142 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0186063 |
| JAK1 | Janus kinase 1 | -0.018582 |
| SPAG9 | sperm associated antigen 9 | -0.0183233 |
| RPL9 | ribosomal protein L9 | -0.0181914 |
| CCNL1 | cyclin L1 | -0.0180887 |
| ANKRD11 | ankyrin repeat domain 11 | -0.0180779 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0180752 |
| RPS29 | ribosomal protein S29 | -0.01796 |
| RBM39 | RNA binding motif protein 39 | -0.0177928 |
| RPL12 | ribosomal protein L12 | -0.0177901 |
| KIAA1217 | KIAA1217 | -0.0176162 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0172711 |
| PNPLA8 | patatin-like phospholipase domain containing 8 | -0.0172144 |
| RPL4 | ribosomal protein L4 | -0.0170608 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0170218 |
| NPTN | neuroplastin | -0.0169935 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | -0.016927 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0165969 |
| NPC1 | Niemann-Pick disease, type C1 | -0.016538 |
| RPS19 | ribosomal protein S19 | -0.0164177 |
| NABP1 | nucleic acid binding protein 1 | -0.0161886 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0161019 |
| PHF20L1 | PHD finger protein 20-like 1 | -0.0160476 |
| ARGLU1 | arginine and glutamate rich 1 | -0.0159464 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0158941 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | -0.0157868 |
| MYH9 | myosin, heavy chain 9, non-muscle | -0.0156872 |
| ECD | ecdysoneless homolog (Drosophila) | -0.015647 |
| NUP58 | nucleoporin 58 | -0.0156177 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0155273 |
| DENND4A | DENN/MADD domain containing 4A | -0.0154101 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.015293 |
| TENT2 | terminal nucleotidyltransferase 2 | -0.0150339 |
| GOLGA4 | golgin A4 | -0.0149544 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0149424 |
