| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.14294 |
| VIM | vimentin | 0.11584 |
| PCBP2 | poly(rC) binding protein 2 | 0.110967 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0896453 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0789627 |
| KDM2A | lysine (K)-specific demethylase 2A | 0.0743595 |
| GOLGA4 | golgin A4 | 0.0720112 |
| RBM39 | RNA binding motif protein 39 | 0.0705321 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.069472 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0578379 |
| PTMA | prothymosin, alpha | 0.0562349 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0552237 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0551912 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0538243 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0502976 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0484524 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0469102 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0466265 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0461705 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0461579 |
| FAM13A | family with sequence similarity 13, member A | 0.0456443 |
| OGA | O-GlcNAcase | 0.0453641 |
| SMAD3 | SMAD family member 3 | 0.0453207 |
| SPAG9 | sperm associated antigen 9 | 0.0436355 |
| MT2A | metallothionein 2A | 0.0417759 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0416981 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0395608 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.039176 |
| FTL | ferritin, light polypeptide | 0.038639 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0379046 |
| SRP54 | signal recognition particle 54kDa | 0.0376904 |
| ATP13A3 | ATPase type 13A3 | 0.0374696 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0362212 |
| RPS12 | ribosomal protein S12 | 0.0360105 |
| ADM | adrenomedullin | 0.0359322 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0357475 |
| RIOK3 | RIO kinase 3 | 0.0353825 |
| ANXA2 | annexin A2 | 0.0352123 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0350601 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0350048 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0348287 |
| KIF5B | kinesin family member 5B | 0.0343533 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0341558 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0337243 |
| CANX | calnexin | 0.032906 |
| HELZ | helicase with zinc finger | 0.0328131 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0326747 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0325371 |
| CALR | calreticulin | 0.0325009 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.030386 |
| POTEF | POTE ankyrin domain family, member F | 0.0301579 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0300323 |
| COPA | coatomer protein complex, subunit alpha | 0.0297971 |
| ANXA1 | annexin A1 | 0.0297495 |
| YME1L1 | YME1-like 1 ATPase | 0.0296458 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0292814 |
| LDHA | lactate dehydrogenase A | 0.0291876 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0290669 |
| B2M | beta-2-microglobulin | 0.0286924 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.0284765 |
| ENO1 | enolase 1, (alpha) | 0.0283605 |
| RNF145 | ring finger protein 145 | 0.0282086 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0281242 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0280749 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0276939 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0271018 |
| C15ORF48 | chromosome 15 open reading frame 48 | 0.0269066 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0268257 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0268046 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0267513 |
| PIK3C2A | phosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha | 0.0267382 |
| RPLP0 | ribosomal protein, large, P0 | 0.0264102 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0262757 |
| RPL12 | ribosomal protein L12 | 0.0262007 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0261363 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0258353 |
| RLF | rearranged L-myc fusion | 0.0257879 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.025732 |
| VMP1 | vacuole membrane protein 1 | 0.0257071 |
| USP3 | ubiquitin specific peptidase 3 | 0.0256621 |
| WDR45B | WD repeat domain 45B | 0.0256273 |
| GDI2 | GDP dissociation inhibitor 2 | 0.0256185 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | 0.0252649 |
| RPS3 | ribosomal protein S3 | 0.0252403 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0251972 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0251789 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0249904 |
| TPR | translocated promoter region, nuclear basket protein | 0.0249722 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0246864 |
| SETD5 | SET domain containing 5 | 0.0246631 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0245467 |
| LMAN1 | lectin, mannose-binding, 1 | 0.0244273 |
| SFTPA2 | surfactant protein A2 | 0.0243154 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0241719 |
| YBX3 | Y box binding protein 3 | 0.0241301 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0240848 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0240776 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0238599 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0235421 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0234371 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.102778 |
| FN1 | fibronectin 1 | -0.0920608 |
| CDH13 | cadherin 13 | -0.0890975 |
| ITPR1 | inositol 1,4,5-trisphosphate receptor, type 1 | -0.086899 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0788606 |
| NRG1 | neuregulin 1 | -0.0665998 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | -0.0568777 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0563436 |
| MTSS1 | metastasis suppressor 1 | -0.0517862 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0516172 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0513415 |
| HMGA2 | high mobility group AT-hook 2 | -0.0490241 |
| MEF2A | myocyte enhancer factor 2A | -0.046666 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0445686 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0427843 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0403211 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0401178 |
| GLCCI1 | glucocorticoid induced 1 | -0.0374741 |
| NRP1 | neuropilin 1 | -0.0357087 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.0344849 |
| ANTXR2 | anthrax toxin receptor 2 | -0.0343251 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0342593 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0318588 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0317794 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0317088 |
| FBN1 | fibrillin 1 | -0.0315951 |
| CLMP | CXADR-like membrane protein | -0.0299317 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0291918 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0275421 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0272906 |
| IL1B | interleukin 1, beta | -0.0269006 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0267838 |
| ITGB3 | integrin, beta 3 (platelet glycoprotein IIIa, antigen CD61) | -0.0266947 |
| OXR1 | oxidation resistance 1 | -0.0253294 |
| TMEM165 | transmembrane protein 165 | -0.0252302 |
| EFNA5 | ephrin-A5 | -0.0245043 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0240681 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0239212 |
| RAI14 | retinoic acid induced 14 | -0.0233615 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0230213 |
| CDK14 | cyclin-dependent kinase 14 | -0.0226475 |
| DTNA | dystrobrevin, alpha | -0.0222845 |
| TMTC1 | transmembrane and tetratricopeptide repeat containing 1 | -0.0219715 |
| COL7A1 | collagen, type VII, alpha 1 | -0.0216579 |
| PRRX1 | paired related homeobox 1 | -0.0212141 |
| CUX1 | cut-like homeobox 1 | -0.0207433 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0206485 |
| JARID2 | jumonji, AT rich interactive domain 2 | -0.0203322 |
| GALNT18 | polypeptide N-acetylgalactosaminyltransferase 18 | -0.0199943 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0196791 |
| SUMF1 | sulfatase modifying factor 1 | -0.0193532 |
| SNX9 | sorting nexin 9 | -0.0191669 |
| SGIP1 | SH3-domain GRB2-like (endophilin) interacting protein 1 | -0.018509 |
| NHSL1 | NHS-like 1 | -0.0184627 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | -0.0183619 |
| GLIS3 | GLIS family zinc finger 3 | -0.0181853 |
| WLS | wntless Wnt ligand secretion mediator | -0.0181224 |
| IFI44L | interferon-induced protein 44-like | -0.0179785 |
| ANXA10 | annexin A10 | -0.0175975 |
| ZNF804A | zinc finger protein 804A | -0.0175435 |
| SEPTIN9 | septin 9 | -0.0175167 |
| CDCP1 | CUB domain containing protein 1 | -0.0173218 |
| PYGL | phosphorylase, glycogen, liver | -0.0172822 |
| CFAP20DC | CFAP20 domain containing | -0.0172494 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.017029 |
| EGFR | epidermal growth factor receptor | -0.0169824 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0168842 |
| RNF213 | ring finger protein 213 | -0.0167146 |
| SLC44A5 | solute carrier family 44, member 5 | -0.0166663 |
| NAV3 | neuron navigator 3 | -0.0165571 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | -0.0165057 |
| MCC | mutated in colorectal cancers | -0.0164855 |
| ENOSF1 | enolase superfamily member 1 | -0.016367 |
| MECOM | MDS1 and EVI1 complex locus | -0.0163382 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0161968 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0161253 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.016038 |
| TMEM131 | transmembrane protein 131 | -0.0158869 |
| GPC6 | glypican 6 | -0.0157346 |
| DNER | delta/notch-like EGF repeat containing | -0.0155195 |
| ARHGAP22 | Rho GTPase activating protein 22 | -0.0155117 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0154956 |
| DIAPH2 | diaphanous-related formin 2 | -0.0154505 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | -0.0151586 |
| AADAC | arylacetamide deacetylase | -0.0150786 |
| ETV6 | ets variant 6 | -0.0149735 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.014967 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0149243 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0147791 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0147531 |
| ANK3 | ankyrin 3, node of Ranvier (ankyrin G) | -0.0147471 |
| EFCAB13 | EF-hand calcium binding domain 13 | -0.0145659 |
| NAV1 | neuron navigator 1 | -0.014513 |
| LRRC8C | leucine rich repeat containing 8 family, member C | -0.0143907 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0143303 |
| PTGIS | prostaglandin I2 (prostacyclin) synthase | -0.0141172 |
| LTBP1 | latent transforming growth factor beta binding protein 1 | -0.0139793 |
| ZC3H12C | zinc finger CCCH-type containing 12C | -0.0139118 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0138267 |
| BMERB1 | bMERB domain containing 1 | -0.013802 |
