| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.121393 |
| ASPH | aspartate beta-hydroxylase | 0.113473 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.104213 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.103086 |
| PRRC2C | proline-rich coiled-coil 2C | 0.101423 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.100126 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0960082 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0848495 |
| PTMA | prothymosin, alpha | 0.0813676 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.078714 |
| FTL | ferritin, light polypeptide | 0.0759119 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0748104 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0725034 |
| MT2A | metallothionein 2A | 0.0700234 |
| PCBP2 | poly(rC) binding protein 2 | 0.0684523 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0668775 |
| SEPTIN9 | septin 9 | 0.0617114 |
| GOLGB1 | golgin B1 | 0.0607513 |
| H3-3B | H3.3 histone B | 0.0599319 |
| CADM1 | cell adhesion molecule 1 | 0.0565457 |
| MCL1 | myeloid cell leukemia 1 | 0.0560772 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0547559 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0538718 |
| DENND5A | DENN/MADD domain containing 5A | 0.0536602 |
| SRSF11 | serine/arginine-rich splicing factor 11 | 0.0532219 |
| HMGA2 | high mobility group AT-hook 2 | 0.053126 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0528989 |
| SPAG9 | sperm associated antigen 9 | 0.0526517 |
| ABI1 | abl-interactor 1 | 0.0505173 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | 0.0502564 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | 0.0495109 |
| FAM13A | family with sequence similarity 13, member A | 0.0494703 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0491146 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0487088 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0481972 |
| VIM | vimentin | 0.0472335 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0469187 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0466624 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0464303 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0459307 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0458761 |
| MATR3 | matrin 3 | 0.0457521 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0455442 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0454681 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0445979 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.04458 |
| B2M | beta-2-microglobulin | 0.0445323 |
| HLA-B | major histocompatibility complex, class I, B | 0.0442467 |
| HELZ | helicase with zinc finger | 0.0435277 |
| RLF | rearranged L-myc fusion | 0.0433876 |
| PCDH9 | protocadherin 9 | 0.0432088 |
| NAV2 | neuron navigator 2 | 0.0430896 |
| FMNL2 | formin-like 2 | 0.0428703 |
| UBR3 | ubiquitin protein ligase E3 component n-recognin 3 (putative) | 0.0426812 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0426414 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0424694 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0415857 |
| BRAF | B-Raf proto-oncogene, serine/threonine kinase | 0.0413529 |
| ADM | adrenomedullin | 0.041282 |
| TMSB10 | thymosin beta 10 | 0.040392 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.0399612 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | 0.039408 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0392812 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0390743 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0390389 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0383016 |
| COPA | coatomer protein complex, subunit alpha | 0.0381497 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0376379 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0376248 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | 0.0375926 |
| HBP1 | HMG-box transcription factor 1 | 0.0373581 |
| MYO10 | myosin X | 0.0371729 |
| STC1 | stanniocalcin 1 | 0.0369941 |
| FNIP1 | folliculin interacting protein 1 | 0.036765 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0365083 |
| WNK1 | WNK lysine deficient protein kinase 1 | 0.036134 |
| CCNI | cyclin I | 0.0359541 |
| OGA | O-GlcNAcase | 0.0358595 |
| MORF4L2 | mortality factor 4 like 2 | 0.035762 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0353414 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0350628 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0347995 |
| DTNA | dystrobrevin, alpha | 0.0344874 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0343692 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0340878 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0338967 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.0338243 |
| LAMB3 | laminin, beta 3 | 0.0333305 |
| RASA2 | RAS p21 protein activator 2 | 0.0332 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.033104 |
| PRELID2 | PRELI domain containing 2 | 0.0327765 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | 0.0321687 |
| APP | amyloid beta (A4) precursor protein | 0.0321239 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0313954 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0309742 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0306075 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0304641 |
| ZFHX3 | zinc finger homeobox 3 | 0.0294545 |
| SBF2 | SET binding factor 2 | 0.0289423 |
| CAMK2D | calcium/calmodulin-dependent protein kinase II delta | 0.0284886 |
| Symbol | Name | Standardized Value |
|---|---|---|
| CD2AP | CD2-associated protein | -0.0881222 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0854443 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0850794 |
| TENM3 | teneurin transmembrane protein 3 | -0.0835577 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0829545 |
| ACTG1 | actin gamma 1 | -0.0801774 |
| GPC6 | glypican 6 | -0.0795032 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0725245 |
| VMP1 | vacuole membrane protein 1 | -0.0723366 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0712152 |
| SMYD3 | SET and MYND domain containing 3 | -0.0694396 |
| NCOA1 | nuclear receptor coactivator 1 | -0.064625 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0634441 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.062438 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.062237 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0602202 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0599431 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0593747 |
| SMG6 | SMG6 nonsense mediated mRNA decay factor | -0.058179 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0581105 |
| KIAA1217 | KIAA1217 | -0.0555472 |
| BTBD9 | BTB (POZ) domain containing 9 | -0.054658 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0544779 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0538365 |
| ERBB2 | erb-b2 receptor tyrosine kinase 2 | -0.0534959 |
| ZNF148 | zinc finger protein 148 | -0.0534712 |
| RB1CC1 | RB1-inducible coiled-coil 1 | -0.0532924 |
| MAP4 | microtubule-associated protein 4 | -0.051336 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0505899 |
| FYN | FYN proto-oncogene, Src family tyrosine kinase | -0.0501247 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0497133 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0489189 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0484284 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0481662 |
| AHNAK | AHNAK nucleoprotein | -0.0480751 |
| RPLP0 | ribosomal protein, large, P0 | -0.0476162 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0467899 |
| SENP6 | SUMO1/sentrin specific peptidase 6 | -0.0466265 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0453881 |
| FOXO3 | forkhead box O3 | -0.0440426 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.043943 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0436058 |
| MYO1D | myosin ID | -0.0427919 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0424394 |
| LDHA | lactate dehydrogenase A | -0.0416171 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.041483 |
| RAB2A | RAB2A, member RAS oncogene family | -0.040799 |
| PKM | pyruvate kinase, muscle | -0.0400231 |
| RPL32 | ribosomal protein L32 | -0.0399807 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0398772 |
| PRKAR1A | protein kinase, cAMP-dependent, regulatory, type I, alpha | -0.0397454 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0396178 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0395635 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0385228 |
| USP15 | ubiquitin specific peptidase 15 | -0.0383918 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0383336 |
| RALGAPA2 | Ral GTPase activating protein, alpha subunit 2 (catalytic) | -0.0380302 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | -0.0366507 |
| SNX14 | sorting nexin 14 | -0.0365951 |
| HDLBP | high density lipoprotein binding protein | -0.0365796 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0362111 |
| ACTN4 | actinin, alpha 4 | -0.0358271 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0357363 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0355383 |
| RAD51B | RAD51 paralog B | -0.0350726 |
| ZNF644 | zinc finger protein 644 | -0.0345721 |
| PEG10 | paternally expressed 10 | -0.034336 |
| FBXO11 | F-box protein 11 | -0.0342787 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | -0.0340687 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.03387 |
| UTRN | utrophin | -0.0333564 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0333242 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0331532 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0330624 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0327185 |
| TNS3 | tensin 3 | -0.0325211 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0321803 |
| FAM162A | family with sequence similarity 162, member A | -0.0316921 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0315334 |
| SQSTM1 | sequestosome 1 | -0.0313543 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | -0.0310108 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0303961 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0301021 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0300437 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0298461 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0298368 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0297664 |
| AUTS2 | autism susceptibility candidate 2 | -0.029683 |
| DUSP6 | dual specificity phosphatase 6 | -0.0294413 |
| CANX | calnexin | -0.0292969 |
| SUCO | SUN domain containing ossification factor | -0.0291661 |
| CDKAL1 | CDK5 regulatory subunit associated protein 1-like 1 | -0.0288016 |
| SSH1 | slingshot protein phosphatase 1 | -0.0287355 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0284386 |
| ANXA2 | annexin A2 | -0.0282399 |
| NBEAL1 | neurobeachin-like 1 | -0.0281522 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | -0.0280157 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0280078 |
| RPS8 | ribosomal protein S8 | -0.0279409 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.0279306 |
