| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.140668 |
| PTMA | prothymosin, alpha | 0.120441 |
| TMSB4X | thymosin beta 4, X-linked | 0.113331 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.100913 |
| MINDY2 | MINDY lysine 48 deubiquitinase 2 | 0.0825508 |
| VCL | vinculin | 0.0813574 |
| ENOX1 | ecto-NOX disulfide-thiol exchanger 1 | 0.0768226 |
| PGK1 | phosphoglycerate kinase 1 | 0.0750994 |
| S100A6 | S100 calcium binding protein A6 | 0.0746049 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.0740834 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0724582 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0714997 |
| EGFR | epidermal growth factor receptor | 0.0698983 |
| DSCAM | Down syndrome cell adhesion molecule | 0.066465 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0626842 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0614733 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0604735 |
| TXNRD1 | thioredoxin reductase 1 | 0.0570046 |
| ENO1 | enolase 1, (alpha) | 0.0560431 |
| LDHA | lactate dehydrogenase A | 0.0553687 |
| SMYD3 | SET and MYND domain containing 3 | 0.055164 |
| RPL12 | ribosomal protein L12 | 0.0551138 |
| FLNB | filamin B, beta | 0.0524614 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.05175 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0513625 |
| B2M | beta-2-microglobulin | 0.0507868 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | 0.0492086 |
| NBEA | neurobeachin | 0.0486277 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0479666 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0475491 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0465304 |
| RPL11 | ribosomal protein L11 | 0.0462352 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0456796 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0455117 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0451294 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.045063 |
| RBM39 | RNA binding motif protein 39 | 0.0446337 |
| PRELID2 | PRELI domain containing 2 | 0.0441814 |
| RPS3 | ribosomal protein S3 | 0.0434786 |
| HDLBP | high density lipoprotein binding protein | 0.0432397 |
| EZR | ezrin | 0.0431041 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.041675 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0415587 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0415559 |
| ANK2 | ankyrin 2, neuronal | 0.0413906 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0411128 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | 0.0410559 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0408111 |
| RPL13A | ribosomal protein L13a | 0.0406056 |
| SQSTM1 | sequestosome 1 | 0.0399395 |
| GOLGA4 | golgin A4 | 0.0395077 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | 0.0393646 |
| RPLP0 | ribosomal protein, large, P0 | 0.0392011 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0385853 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0384877 |
| AHNAK | AHNAK nucleoprotein | 0.038237 |
| PYGB | phosphorylase, glycogen; brain | 0.0375774 |
| FOXP1 | forkhead box P1 | 0.0374553 |
| ROCK1 | Rho-associated, coiled-coil containing protein kinase 1 | 0.0374429 |
| PNISR | PNN-interacting serine/arginine-rich protein | 0.0374143 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0368565 |
| EPRS1 | glutamyl-prolyl-tRNA synthetase 1 | 0.0367057 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | 0.0364457 |
| CALR | calreticulin | 0.0360666 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0355037 |
| RPL19 | ribosomal protein L19 | 0.0350396 |
| ATF4 | activating transcription factor 4 | 0.0348136 |
| PHF3 | PHD finger protein 3 | 0.0347093 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0337174 |
| RTN4 | reticulon 4 | 0.0335061 |
| DIAPH2 | diaphanous-related formin 2 | 0.0327797 |
| RPS19 | ribosomal protein S19 | 0.03257 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0324839 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0324094 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0322003 |
| USP34 | ubiquitin specific peptidase 34 | 0.0314843 |
| LARS1 | leucyl-tRNA synthetase 1 | 0.0312409 |
| RNF145 | ring finger protein 145 | 0.0309059 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0306186 |
| ACTG1 | actin gamma 1 | 0.0303155 |
| RPL26 | ribosomal protein L26 | 0.0300948 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0300811 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0299478 |
| NFIA | nuclear factor I/A | 0.0298613 |
| JMJD1C | jumonji domain containing 1C | 0.0298345 |
| RPL23 | ribosomal protein L23 | 0.0296558 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0296539 |
| PARD3 | par-3 family cell polarity regulator | 0.029462 |
| EFNA5 | ephrin-A5 | 0.0293962 |
| KIF5B | kinesin family member 5B | 0.0292426 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0290832 |
| NCKAP1 | NCK-associated protein 1 | 0.0289925 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0289259 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0287816 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0287021 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0282223 |
| RPS6 | ribosomal protein S6 | 0.0274822 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0274562 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0273972 |
| GDI2 | GDP dissociation inhibitor 2 | 0.02737 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0728287 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0613423 |
| BMP10 | bone morphogenetic protein 10 | -0.0586412 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0430188 |
| NAV2 | neuron navigator 2 | -0.0365287 |
| CENPF | centromere protein F, 350/400kDa | -0.0336535 |
| MKI67 | marker of proliferation Ki-67 | -0.0316086 |
| DIAPH3 | diaphanous-related formin 3 | -0.0268494 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0239794 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0208362 |
| IGF2 | insulin-like growth factor 2 | -0.0201897 |
| FUS | FUS RNA binding protein | -0.0199119 |
| SHC1 | SHC (Src homology 2 domain containing) transforming protein 1 | -0.0190102 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0185209 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | -0.0180419 |
| GSE1 | Gse1 coiled-coil protein | -0.0171448 |
| DEK | DEK proto-oncogene | -0.0165406 |
| HJURP | Holliday junction recognition protein | -0.016518 |
| RFC3 | replication factor C (activator 1) 3, 38kDa | -0.0163151 |
| ATN1 | atrophin 1 | -0.0158401 |
| KIF14 | kinesin family member 14 | -0.015791 |
| RRM2 | ribonucleotide reductase M2 | -0.0155744 |
| SGO2 | shugoshin 2 | -0.0150518 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0148244 |
| FN1 | fibronectin 1 | -0.0147544 |
| TRAK1 | trafficking protein, kinesin binding 1 | -0.0139302 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0138535 |
| HMGB1 | high mobility group box 1 | -0.0136477 |
| HERC3 | HECT and RLD domain containing E3 ubiquitin protein ligase 3 | -0.0134615 |
| ALDH1A2 | aldehyde dehydrogenase 1 family, member A2 | -0.0132814 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0132648 |
| CEP128 | centrosomal protein 128kDa | -0.013162 |
| RPS2 | ribosomal protein S2 | -0.012973 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | -0.012857 |
| KIF18B | kinesin family member 18B | -0.0127909 |
| SYDE1 | synapse defective 1, Rho GTPase, homolog 1 (C. elegans) | -0.0126287 |
| PKM | pyruvate kinase, muscle | -0.0124037 |
| HELZ | helicase with zinc finger | -0.0123838 |
| CENPE | centromere protein E, 312kDa | -0.0123167 |
| FLNA | filamin A, alpha | -0.01231 |
| MYADM | myeloid-associated differentiation marker | -0.0122619 |
| RBM3 | RNA binding motif (RNP1, RRM) protein 3 | -0.0121097 |
| HELLS | helicase, lymphoid-specific | -0.011976 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.011869 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0118262 |
| TENT4A | terminal nucleotidyltransferase 4A | -0.0116523 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.01165 |
| CHD1L | chromodomain helicase DNA binding protein 1-like | -0.0116463 |
| GTSE1 | G-2 and S-phase expressed 1 | -0.0115064 |
| ITGA10 | integrin, alpha 10 | -0.0114025 |
| EMP3 | epithelial membrane protein 3 | -0.0113781 |
| MAPK1IP1L | mitogen-activated protein kinase 1 interacting protein 1-like | -0.0112674 |
| ACTN4 | actinin, alpha 4 | -0.0112496 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0111355 |
| SCLT1 | sodium channel and clathrin linker 1 | -0.0110702 |
| ATAD2 | ATPase family, AAA domain containing 2 | -0.0110438 |
| TLE5 | TLE family member 5, transcriptional modulator | -0.0109198 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0107613 |
| RHOA | ras homolog family member A | -0.0105164 |
| GUK1 | guanylate kinase 1 | -0.0105069 |
| PDE8A | phosphodiesterase 8A | -0.0104375 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0100043 |
| BUB1B | BUB1 mitotic checkpoint serine/threonine kinase B | -0.00996285 |
| PHTF2 | putative homeodomain transcription factor 2 | -0.00996136 |
| KPNB1 | karyopherin (importin) beta 1 | -0.00990343 |
| ANLN | anillin, actin binding protein | -0.0098986 |
| KIF5C | kinesin family member 5C | -0.00986968 |
| SGMS2 | sphingomyelin synthase 2 | -0.00986967 |
| RCOR1 | REST corepressor 1 | -0.00976483 |
| CENPP | centromere protein P | -0.00963481 |
| SPC25 | SPC25, NDC80 kinetochore complex component | -0.00962247 |
| PRC1 | protein regulator of cytokinesis 1 | -0.00952602 |
| SOX9 | SRY (sex determining region Y)-box 9 | -0.00948325 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.00944956 |
| GOLIM4 | golgi integral membrane protein 4 | -0.00939915 |
| LENG8 | leukocyte receptor cluster (LRC) member 8 | -0.00936731 |
| PRMT2IP | PRMT2 interacting protein | -0.00933381 |
| DEPDC1 | DEP domain containing 1 | -0.00929224 |
| LMNA | lamin A/C | -0.00928926 |
| PLXNB2 | plexin B2 | -0.0092222 |
| RPS15 | ribosomal protein S15 | -0.00913191 |
| PDE10A | phosphodiesterase 10A | -0.00911625 |
| NOCT | nocturnin | -0.00910815 |
| PPM1B | protein phosphatase, Mg2+/Mn2+ dependent, 1B | -0.00905092 |
| DYNC1I2 | dynein, cytoplasmic 1, intermediate chain 2 | -0.00895938 |
| TMEM165 | transmembrane protein 165 | -0.00895668 |
| MGME1 | mitochondrial genome maintenance exonuclease 1 | -0.00892283 |
| EVI5 | ecotropic viral integration site 5 | -0.00890305 |
| TIMP2 | TIMP metallopeptidase inhibitor 2 | -0.00878847 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.00873914 |
| RNPS1 | RNA binding protein S1, serine-rich domain | -0.00863376 |
| FOXM1 | forkhead box M1 | -0.00861508 |
| SEC24D | SEC24 family member D | -0.00858519 |
| PVR | poliovirus receptor | -0.00856981 |
| RIPK2 | receptor-interacting serine-threonine kinase 2 | -0.00855744 |
| FARP2 | FERM, RhoGEF and pleckstrin domain protein 2 | -0.00855092 |
| DOCK6 | dedicator of cytokinesis 6 | -0.00850025 |
| CDCA2 | cell division cycle associated 2 | -0.00842892 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | -0.00840806 |
| CIP2A | cellular inhibitor of PP2A | -0.00839144 |
