| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0817871 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0597371 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0555337 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0478954 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0441141 |
| PCBP2 | poly(rC) binding protein 2 | 0.0437931 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0385299 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0379576 |
| ATP13A3 | ATPase type 13A3 | 0.0368616 |
| OGA | O-GlcNAcase | 0.0364508 |
| ARRDC3 | arrestin domain containing 3 | 0.0363453 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0316407 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0308674 |
| MXI1 | MAX interactor 1, dimerization protein | 0.0299543 |
| ICAM1 | intercellular adhesion molecule 1 | 0.029947 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0298643 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.028032 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0279675 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0273661 |
| POTEF | POTE ankyrin domain family, member F | 0.0255848 |
| GOLGA4 | golgin A4 | 0.0255634 |
| USP37 | ubiquitin specific peptidase 37 | 0.0249927 |
| HELZ | helicase with zinc finger | 0.0244223 |
| TSC22D2 | TSC22 domain family, member 2 | 0.023937 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0238171 |
| XPO1 | exportin 1 | 0.0234076 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0229407 |
| ANLN | anillin, actin binding protein | 0.0222886 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0221476 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0220947 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0219921 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0217038 |
| SRP54 | signal recognition particle 54kDa | 0.0214213 |
| ZNF292 | zinc finger protein 292 | 0.0211352 |
| MATR3 | matrin 3 | 0.0208567 |
| RNF145 | ring finger protein 145 | 0.0208038 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0201706 |
| CENPF | centromere protein F, 350/400kDa | 0.0201703 |
| EZR | ezrin | 0.0196089 |
| DSTN | destrin (actin depolymerizing factor) | 0.0195639 |
| TPX2 | TPX2, microtubule-associated | 0.0195539 |
| MYOF | myoferlin | 0.0194425 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0192838 |
| ANXA2 | annexin A2 | 0.0189145 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0188909 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0188454 |
| MSN | moesin | 0.0187654 |
| LAMP2 | lysosomal-associated membrane protein 2 | 0.01862 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0186153 |
| SET | SET nuclear proto-oncogene | 0.0185179 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.018125 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0178363 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0177415 |
| CCNL1 | cyclin L1 | 0.0175168 |
| TPM3 | tropomyosin 3 | 0.0175096 |
| RBM39 | RNA binding motif protein 39 | 0.0172685 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0172079 |
| WDR45B | WD repeat domain 45B | 0.0171783 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0169752 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0168608 |
| SERINC1 | serine incorporator 1 | 0.0167877 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0164652 |
| MKI67 | marker of proliferation Ki-67 | 0.016407 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.0162586 |
| ANO6 | anoctamin 6 | 0.0161413 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.015493 |
| SPAG9 | sperm associated antigen 9 | 0.0154392 |
| PDK3 | pyruvate dehydrogenase kinase, isozyme 3 | 0.0154145 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0153608 |
| OPTN | optineurin | 0.0153017 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0152007 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0151759 |
| NONO | non-POU domain containing, octamer-binding | 0.0151228 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0147436 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0144242 |
| SMAD3 | SMAD family member 3 | 0.014178 |
| NUP153 | nucleoporin 153kDa | 0.0140948 |
| PHIP | pleckstrin homology domain interacting protein | 0.0139956 |
| ARF4 | ADP-ribosylation factor 4 | 0.0139689 |
| SRRM1 | serine/arginine repetitive matrix 1 | 0.0138933 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0137369 |
| PHC3 | polyhomeotic homolog 3 (Drosophila) | 0.0137342 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0135316 |
| SNX3 | sorting nexin 3 | 0.0134887 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0133905 |
| ECPAS | Ecm29 proteasome adaptor and scaffold | 0.0133882 |
| RLF | rearranged L-myc fusion | 0.0132655 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0132637 |
| ZNF451 | zinc finger protein 451 | 0.0131811 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0130855 |
| YTHDC1 | YTH domain containing 1 | 0.0130709 |
| TNRC6A | trinucleotide repeat containing 6A | 0.0130452 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0130383 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.0129909 |
| DDX3Y | DEAD (Asp-Glu-Ala-Asp) box helicase 3, Y-linked | 0.0129021 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0128713 |
| ABCA5 | ATP-binding cassette, sub-family A (ABC1), member 5 | 0.0128408 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0128359 |
| CNNM2 | cyclin and CBS domain divalent metal cation transport mediator 2 | 0.0128307 |
| FNBP1L | formin binding protein 1-like | 0.0127641 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.14702 |
| VIM | vimentin | -0.14449 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.12768 |
| HLA-B | major histocompatibility complex, class I, B | -0.121963 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.117177 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.111618 |
| IER3 | immediate early response 3 | -0.101277 |
| GLIS3 | GLIS family zinc finger 3 | -0.0990222 |
| CD44 | CD44 molecule (Indian blood group) | -0.0851301 |
| CDH13 | cadherin 13 | -0.0808105 |
| HMGA2 | high mobility group AT-hook 2 | -0.0803198 |
| VCL | vinculin | -0.0770711 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.07578 |
| TMSB10 | thymosin beta 10 | -0.0739317 |
| FTL | ferritin, light polypeptide | -0.0730129 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0715384 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0682787 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0678596 |
| HDAC9 | histone deacetylase 9 | -0.0659876 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0603937 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0591266 |
| FRMD4A | FERM domain containing 4A | -0.0584276 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0564379 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0563502 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0551217 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0532169 |
| GRIN2A | glutamate receptor, ionotropic, N-methyl D-aspartate 2A | -0.0515626 |
| HLA-A | major histocompatibility complex, class I, A | -0.0514081 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0513081 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0506109 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0491328 |
| EGR1 | early growth response 1 | -0.0465005 |
| MT2A | metallothionein 2A | -0.0454854 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0441654 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0439524 |
| RPL35A | ribosomal protein L35a | -0.0438142 |
| RPS24 | ribosomal protein S24 | -0.0434234 |
| NABP1 | nucleic acid binding protein 1 | -0.043144 |
| PDE10A | phosphodiesterase 10A | -0.0431178 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0429565 |
| INTS6 | integrator complex subunit 6 | -0.0426692 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0417082 |
| KYNU | kynureninase | -0.0406468 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0405673 |
| NAV1 | neuron navigator 1 | -0.0400397 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0388963 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.038442 |
| DIAPH2 | diaphanous-related formin 2 | -0.0384264 |
| NDRG1 | N-myc downstream regulated 1 | -0.0379679 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.0378242 |
| TMEM132D | transmembrane protein 132D | -0.0369996 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0366539 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0365469 |
| ASPH | aspartate beta-hydroxylase | -0.0364988 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0363263 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0362786 |
| EGFR | epidermal growth factor receptor | -0.0357159 |
| RAD51B | RAD51 paralog B | -0.0353104 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0346144 |
| ENO1 | enolase 1, (alpha) | -0.033997 |
| LDHA | lactate dehydrogenase A | -0.0334995 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0326696 |
| RND3 | Rho family GTPase 3 | -0.0325453 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0324211 |
| RPS8 | ribosomal protein S8 | -0.0304863 |
| DST | dystonin | -0.0304069 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0303796 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0300917 |
| INHBA | inhibin, beta A | -0.0294702 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.0294701 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0293741 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0291281 |
| SP100 | SP100 nuclear antigen | -0.0291159 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0289399 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0288075 |
| GPC6 | glypican 6 | -0.0287199 |
| RAI14 | retinoic acid induced 14 | -0.0286782 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0285657 |
| CTSD | cathepsin D | -0.028467 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0278262 |
| RPL9 | ribosomal protein L9 | -0.0276198 |
| TMSB4X | thymosin beta 4, X-linked | -0.0274824 |
| HLA-E | major histocompatibility complex, class I, E | -0.0272581 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0272504 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0269923 |
| ATXN1 | ataxin 1 | -0.026455 |
| RPL23 | ribosomal protein L23 | -0.0264328 |
| SQSTM1 | sequestosome 1 | -0.0263025 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0259201 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0257381 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0257336 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0257108 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0256665 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0253777 |
| AHNAK | AHNAK nucleoprotein | -0.025364 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0253437 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0249466 |
| RPL37A | ribosomal protein L37a | -0.0247831 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0243727 |
| KRT19 | keratin 19, type I | -0.0243596 |
