| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Darolutamide perturbation in SW 900 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Darolutamide_SW 900 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.082012 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0479228 |
| TPR | translocated promoter region, nuclear basket protein | 0.0429659 |
| OGA | O-GlcNAcase | 0.0396121 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.03747 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0347765 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0328396 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.029798 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0297491 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.028559 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0282147 |
| CD109 | CD109 molecule | 0.027611 |
| CENPF | centromere protein F, 350/400kDa | 0.0256202 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.025537 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0248599 |
| RNF145 | ring finger protein 145 | 0.0233292 |
| NEK7 | NIMA-related kinase 7 | 0.0231254 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0225072 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0223037 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0222766 |
| GOLGA4 | golgin A4 | 0.0222596 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0219416 |
| BTAF1 | BTAF1 RNA polymerase II, B-TFIID transcription factor-associated, 170kDa | 0.0217371 |
| SUCO | SUN domain containing ossification factor | 0.0216801 |
| RBM25 | RNA binding motif protein 25 | 0.0214934 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0211872 |
| CEP350 | centrosomal protein 350kDa | 0.0208378 |
| RPS12 | ribosomal protein S12 | 0.0208357 |
| SERINC1 | serine incorporator 1 | 0.0203855 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0202574 |
| RBM39 | RNA binding motif protein 39 | 0.0197209 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.019525 |
| NUP58 | nucleoporin 58 | 0.0194312 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.019419 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0193802 |
| AFDN | afadin, adherens junction formation factor | 0.0190492 |
| XPO1 | exportin 1 | 0.018818 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0187599 |
| TMF1 | TATA element modulatory factor 1 | 0.0184946 |
| EREG | epiregulin | 0.0182957 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0181242 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.018067 |
| HELZ | helicase with zinc finger | 0.0178605 |
| PELO | pelota homolog (Drosophila) | 0.0178587 |
| ARRDC3 | arrestin domain containing 3 | 0.0176611 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | 0.0173994 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0173547 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0173172 |
| ZFC3H1 | zinc finger, C3H1-type containing | 0.0172264 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.016964 |
| INSIG2 | insulin induced gene 2 | 0.0168425 |
| YTHDC1 | YTH domain containing 1 | 0.0168341 |
| COPA | coatomer protein complex, subunit alpha | 0.0168043 |
| SDC4 | syndecan 4 | 0.0167811 |
| MIS18BP1 | MIS18 binding protein 1 | 0.0167012 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0166851 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.016424 |
| TPX2 | TPX2, microtubule-associated | 0.0163042 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0161431 |
| MKRN1 | makorin ring finger protein 1 | 0.0158187 |
| DHX15 | DEAH (Asp-Glu-Ala-His) box helicase 15 | 0.0156115 |
| GPBP1 | GC-rich promoter binding protein 1 | 0.015488 |
| PPP2R5E | protein phosphatase 2, regulatory subunit B', epsilon isoform | 0.0154875 |
| HNRNPDL | heterogeneous nuclear ribonucleoprotein D-like | 0.015418 |
| CLINT1 | clathrin interactor 1 | 0.0152842 |
| SPAG9 | sperm associated antigen 9 | 0.015149 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0151328 |
| MLEC | malectin | 0.0150144 |
| CDC73 | cell division cycle 73 | 0.0149635 |
| PPP3R1 | protein phosphatase 3, regulatory subunit B, alpha | 0.0148107 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0147554 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0146818 |
| PCBP2 | poly(rC) binding protein 2 | 0.0146533 |
| HMGB2 | high mobility group box 2 | 0.0145997 |
| HBP1 | HMG-box transcription factor 1 | 0.0145738 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.0144621 |
| TIAL1 | TIA1 cytotoxic granule-associated RNA binding protein-like 1 | 0.0144003 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0142746 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0142391 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0141728 |
| KIF5B | kinesin family member 5B | 0.0141247 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0140822 |
| FAT1 | FAT atypical cadherin 1 | 0.014043 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0140394 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0138909 |
| ANLN | anillin, actin binding protein | 0.0137576 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0137522 |
| WDR45B | WD repeat domain 45B | 0.0136913 |
| ZNF841 | zinc finger protein 841 | 0.0136651 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0136484 |
| ANO6 | anoctamin 6 | 0.0136014 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | 0.0136011 |
| PRPF3 | pre-mRNA processing factor 3 | 0.013523 |
| SRP54 | signal recognition particle 54kDa | 0.0135133 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0135054 |
| PRPF39 | pre-mRNA processing factor 39 | 0.0133564 |
| SAFB2 | scaffold attachment factor B2 | 0.0132316 |
| WDR43 | WD repeat domain 43 | 0.0132075 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0131326 |
| ETNK1 | ethanolamine kinase 1 | 0.0131086 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NRG1 | neuregulin 1 | -0.368299 |
| FN1 | fibronectin 1 | -0.326834 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.285234 |
| HMGA2 | high mobility group AT-hook 2 | -0.202684 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.116051 |
| ASPH | aspartate beta-hydroxylase | -0.095183 |
| ITGA1 | integrin, alpha 1 | -0.0930395 |
| TMEM156 | transmembrane protein 156 | -0.0889331 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0825512 |
| TMSB10 | thymosin beta 10 | -0.0798704 |
| GLIS3 | GLIS family zinc finger 3 | -0.0790192 |
| SYT1 | synaptotagmin I | -0.0759679 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0710456 |
| STC2 | stanniocalcin 2 | -0.0702894 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0699454 |
| NRP1 | neuropilin 1 | -0.0664803 |
| EFNA5 | ephrin-A5 | -0.0644844 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | -0.0599221 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0594701 |
| FTL | ferritin, light polypeptide | -0.058546 |
| HLA-B | major histocompatibility complex, class I, B | -0.0548843 |
| GRB10 | growth factor receptor-bound protein 10 | -0.054646 |
| RAI14 | retinoic acid induced 14 | -0.0541887 |
| KLHL5 | kelch-like family member 5 | -0.0534107 |
| MAP1B | microtubule-associated protein 1B | -0.0525673 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0525562 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0521285 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0506792 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.049216 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0488905 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0478025 |
| S100A6 | S100 calcium binding protein A6 | -0.0473973 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0471521 |
| HMGA1 | high mobility group AT-hook 1 | -0.0459432 |
| CDH11 | cadherin 11, type 2, OB-cadherin (osteoblast) | -0.044918 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0438607 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0433483 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0422032 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0414612 |
| OSMR | oncostatin M receptor | -0.0407248 |
| NTN4 | netrin 4 | -0.0401352 |
| DNAH5 | dynein, axonemal, heavy chain 5 | -0.0390684 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0390535 |
| ACTG1 | actin gamma 1 | -0.0389902 |
| NDRG1 | N-myc downstream regulated 1 | -0.0388337 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0380993 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0379763 |
| RNF213 | ring finger protein 213 | -0.0376498 |
| ETV1 | ets variant 1 | -0.0375902 |
| PTMA | prothymosin, alpha | -0.0369574 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0369534 |
| LY6E | lymphocyte antigen 6 complex, locus E | -0.0367726 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0367347 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0362144 |
| EGR1 | early growth response 1 | -0.0355541 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0353849 |
| VCL | vinculin | -0.035028 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0349468 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0347587 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0346004 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0345453 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0342488 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0341837 |
| RANBP17 | RAN binding protein 17 | -0.0339113 |
| TMEM165 | transmembrane protein 165 | -0.0332683 |
| IFI44L | interferon-induced protein 44-like | -0.0329726 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.032821 |
| RASAL2 | RAS protein activator like 2 | -0.0318073 |
| SEPTIN9 | septin 9 | -0.0316573 |
| PKM | pyruvate kinase, muscle | -0.0311598 |
| AEBP2 | AE binding protein 2 | -0.0311439 |
| MX2 | MX dynamin-like GTPase 2 | -0.031091 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.0305958 |
| TENM4 | teneurin transmembrane protein 4 | -0.0300992 |
| LMNA | lamin A/C | -0.030093 |
| PRKCA | protein kinase C, alpha | -0.0300083 |
| TNS3 | tensin 3 | -0.0295735 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.029528 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0289354 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0282429 |
| PTK2 | protein tyrosine kinase 2 | -0.0282289 |
| FOXP1 | forkhead box P1 | -0.0279889 |
| VEGFA | vascular endothelial growth factor A | -0.0279448 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0272789 |
| SLC35F3 | solute carrier family 35, member F3 | -0.027273 |
| IFI16 | interferon, gamma-inducible protein 16 | -0.027218 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0269619 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0269043 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0264184 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0263599 |
| BPTF | bromodomain PHD finger transcription factor | -0.026327 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0259302 |
| PARD3 | par-3 family cell polarity regulator | -0.0258156 |
| DENND5B | DENN/MADD domain containing 5B | -0.0256518 |
| S100A9 | S100 calcium binding protein A9 | -0.0254157 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0252337 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0252266 |
| RTN4 | reticulon 4 | -0.0252136 |
| PALLD | palladin, cytoskeletal associated protein | -0.0251492 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0250204 |
