| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LOX | lysyl oxidase | 0.201522 |
| AHNAK | AHNAK nucleoprotein | 0.16964 |
| FBN1 | fibrillin 1 | 0.116827 |
| COL5A1 | collagen, type V, alpha 1 | 0.114497 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.114193 |
| PODXL | podocalyxin-like | 0.105992 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.104926 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.088013 |
| NAV1 | neuron navigator 1 | 0.0854842 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0828714 |
| FLNA | filamin A, alpha | 0.0779793 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0778929 |
| COL5A2 | collagen, type V, alpha 2 | 0.077596 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0767152 |
| APP | amyloid beta (A4) precursor protein | 0.0760367 |
| THBS2 | thrombospondin 2 | 0.0696071 |
| COL3A1 | collagen, type III, alpha 1 | 0.0637034 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0632836 |
| FSTL1 | follistatin-like 1 | 0.0616739 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.05672 |
| HDLBP | high density lipoprotein binding protein | 0.0556083 |
| SEPTIN9 | septin 9 | 0.0554329 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0540755 |
| PLEC | plectin | 0.0511861 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0486818 |
| FLNB | filamin B, beta | 0.047047 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0426153 |
| AHNAK2 | AHNAK nucleoprotein 2 | 0.0423217 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | 0.040648 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.040568 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0405379 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.04052 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | 0.040117 |
| CALR | calreticulin | 0.0400294 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0395345 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0393031 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0388918 |
| GLIS3 | GLIS family zinc finger 3 | 0.0384499 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0374548 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0367767 |
| MB21D2 | Mab-21 domain containing 2 | 0.0367281 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0365944 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0361993 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0359515 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0356288 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0354257 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0336101 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0335271 |
| PKM | pyruvate kinase, muscle | 0.0331916 |
| DST | dystonin | 0.0331665 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0326133 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0325468 |
| ARRDC3 | arrestin domain containing 3 | 0.0324761 |
| EZR | ezrin | 0.0323746 |
| SLC22A23 | solute carrier family 22, member 23 | 0.0321445 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0320135 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0316988 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.031492 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0308458 |
| ADAM19 | ADAM metallopeptidase domain 19 | 0.0300776 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0298707 |
| RPL3 | ribosomal protein L3 | 0.0297639 |
| NCKAP1 | NCK-associated protein 1 | 0.0296635 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.029309 |
| MSI2 | musashi RNA-binding protein 2 | 0.0290546 |
| LOXL2 | lysyl oxidase-like 2 | 0.0283578 |
| PIEZO1 | piezo-type mechanosensitive ion channel component 1 | 0.0276255 |
| FN1 | fibronectin 1 | 0.0273962 |
| C1D | C1D nuclear receptor corepressor | 0.026418 |
| ADAR | adenosine deaminase, RNA-specific | 0.0258224 |
| VEGFC | vascular endothelial growth factor C | 0.0253465 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0250696 |
| CTSB | cathepsin B | 0.0250293 |
| CEP250 | centrosomal protein 250kDa | 0.0243902 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0239566 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0238969 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0238266 |
| NAV2 | neuron navigator 2 | 0.0237139 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0236684 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0233881 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0233123 |
| SERINC1 | serine incorporator 1 | 0.0231485 |
| MSN | moesin | 0.0225371 |
| EGFR | epidermal growth factor receptor | 0.0224837 |
| UBAP2L | ubiquitin associated protein 2-like | 0.0223462 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0221553 |
| AUTS2 | autism susceptibility candidate 2 | 0.0220326 |
| OGA | O-GlcNAcase | 0.0219244 |
| ATP13A3 | ATPase type 13A3 | 0.0216952 |
| COL6A1 | collagen, type VI, alpha 1 | 0.021656 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0215951 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | 0.0213233 |
| RNF144A | ring finger protein 144A | 0.0212899 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0212539 |
| LDHA | lactate dehydrogenase A | 0.0209974 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | 0.0208465 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0207491 |
| AFDN | afadin, adherens junction formation factor | 0.0207415 |
| ACTN4 | actinin, alpha 4 | 0.0207392 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0206547 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.178949 |
| MT2A | metallothionein 2A | -0.15187 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.148904 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0699861 |
| PTMA | prothymosin, alpha | -0.0664188 |
| NDRG1 | N-myc downstream regulated 1 | -0.0583088 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0479024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.043734 |
| CSTB | cystatin B (stefin B) | -0.0417638 |
| MYADM | myeloid-associated differentiation marker | -0.041143 |
| SEPTIN7 | septin 7 | -0.0393275 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0386767 |
| S100A6 | S100 calcium binding protein A6 | -0.0382308 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0381503 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.038039 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0368932 |
| TMSB10 | thymosin beta 10 | -0.0365401 |
| RPL35A | ribosomal protein L35a | -0.0359052 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0353882 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0348115 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0338108 |
| UGCG | UDP-glucose ceramide glucosyltransferase | -0.033499 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0332385 |
| SLC38A1 | solute carrier family 38, member 1 | -0.032511 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.031906 |
| MX2 | MX dynamin-like GTPase 2 | -0.0316927 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0316418 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0314249 |
| RPLP1 | ribosomal protein, large, P1 | -0.0314247 |
| RPS8 | ribosomal protein S8 | -0.0314062 |
| RPS6 | ribosomal protein S6 | -0.0305684 |
| GOLGA4 | golgin A4 | -0.0300264 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0299944 |
| MT1X | metallothionein 1X | -0.0299579 |
| PSMA7 | proteasome (prosome, macropain) subunit, alpha type, 7 | -0.0298722 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0298005 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0296517 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0296122 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0295369 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0292084 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0291631 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0290379 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0282721 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0280131 |
| PFN1 | profilin 1 | -0.0279791 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.027955 |
| STC1 | stanniocalcin 1 | -0.0274893 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0273998 |
| B2M | beta-2-microglobulin | -0.0266548 |
| RTN4 | reticulon 4 | -0.026583 |
| TPM4 | tropomyosin 4 | -0.0264138 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0262957 |
| HLA-B | major histocompatibility complex, class I, B | -0.0258981 |
| CXXC5 | CXXC finger protein 5 | -0.0252316 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.024278 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.024216 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0236464 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0233573 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0232521 |
| RPL12 | ribosomal protein L12 | -0.0231215 |
| ZNF292 | zinc finger protein 292 | -0.0231204 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0229016 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0225585 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0225253 |
| CBX3 | chromobox homolog 3 | -0.021746 |
| PCBP2 | poly(rC) binding protein 2 | -0.0217182 |
| PRKD3 | protein kinase D3 | -0.020971 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0208848 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.020664 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.020632 |
| JUN | jun proto-oncogene | -0.0206211 |
| RND3 | Rho family GTPase 3 | -0.020604 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0205831 |
| ISG15 | ISG15 ubiquitin-like modifier | -0.0202956 |
| IRF1 | interferon regulatory factor 1 | -0.0202631 |
| PRKRIP1 | PRKR interacting protein 1 (IL11 inducible) | -0.0198459 |
| ZNF148 | zinc finger protein 148 | -0.019736 |
| HIP1 | huntingtin interacting protein 1 | -0.01973 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0195698 |
| RNF24 | ring finger protein 24 | -0.0195253 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0191939 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0191214 |
| ADM | adrenomedullin | -0.0190387 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0188182 |
| SETD5 | SET domain containing 5 | -0.0187523 |
| SBF2 | SET binding factor 2 | -0.0187512 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0185111 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0184196 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.018329 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0182461 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0180037 |
| EIF2AK3 | eukaryotic translation initiation factor 2-alpha kinase 3 | -0.0178942 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0178843 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0176337 |
| SUCNR1 | succinate receptor 1 | -0.0176337 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0176318 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0176302 |
| KIF13A | kinesin family member 13A | -0.0176241 |
| S100A4 | S100 calcium binding protein A4 | -0.0176133 |
| FOSL1 | FOS-like antigen 1 | -0.017611 |
