| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Decitabine_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.100769 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | 0.0953802 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0882968 |
| ASPH | aspartate beta-hydroxylase | 0.0819528 |
| EHBP1 | EH domain binding protein 1 | 0.0719983 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0709214 |
| HMGA2 | high mobility group AT-hook 2 | 0.0688102 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | 0.0673202 |
| MMP12 | matrix metallopeptidase 12 | 0.0616228 |
| PTMA | prothymosin, alpha | 0.0586073 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0575584 |
| CALR | calreticulin | 0.0554807 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0551672 |
| VMP1 | vacuole membrane protein 1 | 0.0549457 |
| NHSL1 | NHS-like 1 | 0.0546301 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | 0.0540332 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0534692 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0530301 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0522559 |
| TAS2R14 | taste receptor, type 2, member 14 | 0.0521965 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0516325 |
| TPM3 | tropomyosin 3 | 0.0513688 |
| RPL3 | ribosomal protein L3 | 0.0509047 |
| YEATS2 | YEATS domain containing 2 | 0.0502471 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0498792 |
| RPL37 | ribosomal protein L37 | 0.0489944 |
| RPS12 | ribosomal protein S12 | 0.0478915 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0476352 |
| USP34 | ubiquitin specific peptidase 34 | 0.0467283 |
| ACTG1 | actin gamma 1 | 0.045843 |
| AHNAK | AHNAK nucleoprotein | 0.0448262 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.043797 |
| NEBL | nebulette | 0.0429591 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0424553 |
| ANXA1 | annexin A1 | 0.0422338 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0400059 |
| NLGN1 | neuroligin 1 | 0.0399278 |
| RRM2 | ribonucleotide reductase M2 | 0.0398026 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0394559 |
| BCHE | butyrylcholinesterase | 0.0392531 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0382465 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0379751 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0368547 |
| RPL37A | ribosomal protein L37a | 0.0368177 |
| EZR | ezrin | 0.0359785 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0354948 |
| RPS27A | ribosomal protein S27a | 0.0346662 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0343372 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | 0.0343368 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.034208 |
| CANX | calnexin | 0.0335623 |
| MKI67 | marker of proliferation Ki-67 | 0.0333377 |
| ANKRD28 | ankyrin repeat domain 28 | 0.0329539 |
| MTAP | methylthioadenosine phosphorylase | 0.0326464 |
| R3HDM2 | R3H domain containing 2 | 0.0324364 |
| CUX1 | cut-like homeobox 1 | 0.0321825 |
| TPM4 | tropomyosin 4 | 0.0318381 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.031323 |
| PDGFC | platelet derived growth factor C | 0.0312674 |
| SMYD3 | SET and MYND domain containing 3 | 0.0309701 |
| RAD51B | RAD51 paralog B | 0.0308259 |
| ATP9A | ATPase, class II, type 9A | 0.0306179 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0305372 |
| RPS3 | ribosomal protein S3 | 0.0304397 |
| VCAN | versican | 0.0301016 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0298549 |
| FNIP1 | folliculin interacting protein 1 | 0.029677 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0290982 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.028755 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | 0.0287544 |
| TMEM41B | transmembrane protein 41B | 0.0287172 |
| YAP1 | Yes-associated protein 1 | 0.0284747 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0283898 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.028339 |
| SPATS2 | spermatogenesis associated, serine-rich 2 | 0.0282132 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0279232 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | 0.027882 |
| XPOT | exportin, tRNA | 0.0278085 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0272791 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0271425 |
| ENO1 | enolase 1, (alpha) | 0.026972 |
| CCT7 | chaperonin containing TCP1, subunit 7 (eta) | 0.0268684 |
| KDM4C | lysine (K)-specific demethylase 4C | 0.0267204 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0266611 |
| MTCL1 | microtubule crosslinking factor 1 | 0.0266437 |
| RPL26 | ribosomal protein L26 | 0.026502 |
| TNRC18 | trinucleotide repeat containing 18 | 0.0262838 |
| RPL38 | ribosomal protein L38 | 0.0262487 |
| WDPCP | WD repeat containing planar cell polarity effector | 0.0262408 |
| SMC1A | structural maintenance of chromosomes 1A | 0.0261446 |
| WWOX | WW domain containing oxidoreductase | 0.026069 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0259203 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | 0.0258634 |
| EXOC4 | exocyst complex component 4 | 0.0255449 |
| PLEC | plectin | 0.0250826 |
| FDPS | farnesyl diphosphate synthase | 0.0249897 |
| H1-4 | H1.4 linker histone, cluster member | 0.0247619 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | 0.0247163 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247055 |
| PDS5A | PDS5 cohesin associated factor A | 0.0242323 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0895831 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0833902 |
| AREG | amphiregulin | -0.0707195 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0700299 |
| CELF2 | CUGBP, Elav-like family member 2 | -0.0629929 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0591294 |
| FTL | ferritin, light polypeptide | -0.0575375 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.054998 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0528208 |
| OXR1 | oxidation resistance 1 | -0.0527579 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0467893 |
| EDN1 | endothelin 1 | -0.0433009 |
| PCBP2 | poly(rC) binding protein 2 | -0.0426262 |
| PFN1 | profilin 1 | -0.0417434 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0411378 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0401585 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0383845 |
| NEK7 | NIMA-related kinase 7 | -0.0383697 |
| HMGA1 | high mobility group AT-hook 1 | -0.0373416 |
| PEG10 | paternally expressed 10 | -0.0371894 |
| CXADR | coxsackie virus and adenovirus receptor | -0.036179 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0355815 |
| DHX36 | DEAH (Asp-Glu-Ala-His) box polypeptide 36 | -0.0352693 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0341721 |
| MED13L | mediator complex subunit 13-like | -0.0339816 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | -0.0328395 |
| AXIN2 | axin 2 | -0.031962 |
| CBX3 | chromobox homolog 3 | -0.0315539 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0314425 |
| MPG | N-methylpurine-DNA glycosylase | -0.0313364 |
| CCNL1 | cyclin L1 | -0.0312818 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0310839 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0297829 |
| MEF2C | myocyte enhancer factor 2C | -0.029467 |
| YBX1 | Y box binding protein 1 | -0.0292973 |
| VIM | vimentin | -0.0291379 |
| POTEF | POTE ankyrin domain family, member F | -0.0290218 |
| CENPF | centromere protein F, 350/400kDa | -0.0289533 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0287279 |
| WDR43 | WD repeat domain 43 | -0.0283184 |
| QKI | QKI, KH domain containing, RNA binding | -0.0282506 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0279924 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0279688 |
| UBE2B | ubiquitin-conjugating enzyme E2B | -0.0278978 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0278236 |
| CCND1 | cyclin D1 | -0.0275782 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0273642 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.027238 |
| USP15 | ubiquitin specific peptidase 15 | -0.0271082 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0269602 |
| XPO1 | exportin 1 | -0.0264476 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0264034 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | -0.0261873 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0261766 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0259766 |
| KIF2A | kinesin heavy chain member 2A | -0.0255748 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0255625 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.025499 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0254282 |
| HSPB1 | heat shock 27kDa protein 1 | -0.0252929 |
| RAB3GAP1 | RAB3 GTPase activating protein subunit 1 (catalytic) | -0.0252139 |
| RPLP1 | ribosomal protein, large, P1 | -0.0251512 |
| CCDC88A | coiled-coil domain containing 88A | -0.0250571 |
| TXNRD1 | thioredoxin reductase 1 | -0.0248848 |
| ATP11A | ATPase, class VI, type 11A | -0.0247224 |
| PRRC2C | proline-rich coiled-coil 2C | -0.0245005 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0244185 |
| WBP11 | WW domain binding protein 11 | -0.0243498 |
| KIF5B | kinesin family member 5B | -0.0241881 |
| ADAM17 | ADAM metallopeptidase domain 17 | -0.0240601 |
| TFG | TRK-fused gene | -0.0240185 |
| PIK3CA | phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha | -0.0238023 |
| ERBIN | erbb2 interacting protein | -0.0237953 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0232919 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0232852 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.02316 |
| DUSP6 | dual specificity phosphatase 6 | -0.0231009 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0229618 |
| AHR | aryl hydrocarbon receptor | -0.0229323 |
| MON2 | MON2 homolog (S. cerevisiae) | -0.0228366 |
| APBB2 | amyloid beta (A4) precursor protein-binding, family B, member 2 | -0.0226842 |
| TMSB10 | thymosin beta 10 | -0.0226219 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0220837 |
| TMEM131 | transmembrane protein 131 | -0.0220504 |
| SEC62 | SEC62 homolog (S. cerevisiae) | -0.0215685 |
| RPL35A | ribosomal protein L35a | -0.0215363 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0215252 |
| AP3S1 | adaptor-related protein complex 3, sigma 1 subunit | -0.0215115 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0214452 |
| RLF | rearranged L-myc fusion | -0.0212802 |
| PLK2 | polo-like kinase 2 | -0.0210818 |
| COG5 | component of oligomeric golgi complex 5 | -0.0209848 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0207629 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | -0.0205274 |
| ZNF148 | zinc finger protein 148 | -0.0203967 |
| FBXO11 | F-box protein 11 | -0.0202986 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0202787 |
| AFTPH | aftiphilin | -0.0202042 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0201303 |
| SON | SON DNA binding protein | -0.0200668 |