Decitabine_COLO 205 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Decitabine perturbation in COLO 205 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Decitabine_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.135315
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 0.0975635
NDRG1 N-myc downstream regulated 1 0.0765747
LOC112694756 uncharaterized LOC112694756 0.0728277
MYH9 myosin, heavy chain 9, non-muscle 0.0725993
SPTBN1 spectrin, beta, non-erythrocytic 1 0.0616545
RUNX1 runt-related transcription factor 1 0.0583927
DSCAM Down syndrome cell adhesion molecule 0.0574988
ARRDC3 arrestin domain containing 3 0.0568485
MBNL2 muscleblind-like splicing regulator 2 0.0561159
RNF149 ring finger protein 149 0.055059
P4HA1 prolyl 4-hydroxylase, alpha polypeptide I 0.0523709
UBR2 ubiquitin protein ligase E3 component n-recognin 2 0.0488096
CALR calreticulin 0.0468313
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0450397
H1-0 H1.0 linker histone 0.0447239
RNF43 ring finger protein 43 0.0442894
ZMYND8 zinc finger, MYND-type containing 8 0.0435975
IFNGR1 interferon gamma receptor 1 0.0431292
EHF ets homologous factor 0.0427571
HDLBP high density lipoprotein binding protein 0.0425022
UBC ubiquitin C 0.0412006
B4GALT5 UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 0.0411589
ELF3 E74-like factor 3 (ets domain transcription factor, epithelial-specific ) 0.0408571
STK24 serine/threonine kinase 24 0.0400625
TOP2A topoisomerase (DNA) II alpha 170kDa 0.0400113
ARGLU1 arginine and glutamate rich 1 0.0393835
TXNIP thioredoxin interacting protein 0.0392613
ST14 suppression of tumorigenicity 14 (colon carcinoma) 0.0385016
ERRFI1 ERBB receptor feedback inhibitor 1 0.0382516
SORBS1 sorbin and SH3 domain containing 1 0.0380986
FNDC3A fibronectin type III domain containing 3A 0.0363507
AFF1 AF4/FMR2 family, member 1 0.0353971
LRCH1 leucine-rich repeats and calponin homology (CH) domain containing 1 0.0347177
NRIP1 nuclear receptor interacting protein 1 0.0346496
TM9SF2 transmembrane 9 superfamily member 2 0.0340994
PDK3 pyruvate dehydrogenase kinase, isozyme 3 0.0335235
MGAT5 mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase 0.0329125
BHLHE40 basic helix-loop-helix family, member e40 0.0328794
SREBF2 sterol regulatory element binding transcription factor 2 0.032657
AHNAK AHNAK nucleoprotein 0.0324561
PKM pyruvate kinase, muscle 0.0323185
CPEB4 cytoplasmic polyadenylation element binding protein 4 0.0322627
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0319927
SLC2A1 solute carrier family 2 (facilitated glucose transporter), member 1 0.0316243
PCK1 phosphoenolpyruvate carboxykinase 1 (soluble) 0.0315881
DSPP dentin sialophosphoprotein 0.0314304
OGA O-GlcNAcase 0.0304865
ESYT2 extended synaptotagmin-like protein 2 0.0304265
ACTN4 actinin, alpha 4 0.0301869
RPL3 ribosomal protein L3 0.0299788
PTBP3 polypyrimidine tract binding protein 3 0.0294734
P4HB prolyl 4-hydroxylase, beta polypeptide 0.0290598
YEATS2 YEATS domain containing 2 0.0284138
PTEN phosphatase and tensin homolog 0.0283431
COG6 component of oligomeric golgi complex 6 0.0280336
CCNL1 cyclin L1 0.0279314
DDIT4 DNA-damage-inducible transcript 4 0.0279277
GBE1 glucan (1,4-alpha-), branching enzyme 1 0.0278965
KLF3 Kruppel-like factor 3 (basic) 0.0274113
CTNND1 catenin (cadherin-associated protein), delta 1 0.0269293
FNIP1 folliculin interacting protein 1 0.0269256
UBR5 ubiquitin protein ligase E3 component n-recognin 5 0.0264415
FOSL2 FOS-like antigen 2 0.0263452
ZKSCAN1 zinc finger with KRAB and SCAN domains 1 0.0262477
PDIA4 protein disulfide isomerase family A, member 4 0.026123
FLNB filamin B, beta 0.0260561
SRRM2 serine/arginine repetitive matrix 2 0.0259185
ABHD2 abhydrolase domain containing 2 0.0258895
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 0.0250608
APLP2 amyloid beta (A4) precursor-like protein 2 0.0250123
MBOAT2 membrane bound O-acyltransferase domain containing 2 0.0248152
RRBP1 ribosome binding protein 1 0.0248086
NCOR1 nuclear receptor corepressor 1 0.024629
PTPRF protein tyrosine phosphatase, receptor type, F 0.0244621
PHC3 polyhomeotic homolog 3 (Drosophila) 0.0243861
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0242998
EIF4G2 eukaryotic translation initiation factor 4 gamma, 2 0.0239703
TMPRSS4 transmembrane protease, serine 4 0.0237386
SEC24D SEC24 family member D 0.023651
FAT1 FAT atypical cadherin 1 0.0234574
SNTB1 syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) 0.0234374
ATP11A ATPase, class VI, type 11A 0.0234178
GOLGA4 golgin A4 0.0233773
TSC22D2 TSC22 domain family, member 2 0.0233706
BCLAF1 BCL2-associated transcription factor 1 0.0233536
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa 0.0233324
TTC3 tetratricopeptide repeat domain 3 0.0233219
SBF2 SET binding factor 2 0.0227924
DNAJC3 DnaJ (Hsp40) homolog, subfamily C, member 3 0.022563
CANX calnexin 0.0224109
KDM3A lysine (K)-specific demethylase 3A 0.0223553
PTPRJ protein tyrosine phosphatase, receptor type, J 0.0223397
OGT O-linked N-acetylglucosamine (GlcNAc) transferase 0.0222247
PRELID2 PRELI domain containing 2 0.022108
SERINC3 serine incorporator 3 0.0219873
HIVEP3 human immunodeficiency virus type I enhancer binding protein 3 0.0218158
TSC22D1 TSC22 domain family, member 1 0.0217874
TPI1 triosephosphate isomerase 1 0.021771
NKD1 naked cuticle homolog 1 (Drosophila) 0.0216006

decreased expression

Symbol Name Standardized Value
EPSTI1 epithelial stromal interaction 1 (breast) -0.139397
STAT1 signal transducer and activator of transcription 1, 91kDa -0.102425
LYZ lysozyme -0.0887665
RIGI RNA sensor RIG-I -0.0822862
SP100 SP100 nuclear antigen -0.0786357
MX1 MX dynamin-like GTPase 1 -0.0738016
EIF2AK2 eukaryotic translation initiation factor 2-alpha kinase 2 -0.0700027
ANXA2 annexin A2 -0.068729
MX2 MX dynamin-like GTPase 2 -0.0684938
SYNE2 spectrin repeat containing, nuclear envelope 2 -0.0659712
STS steroid sulfatase (microsomal), isozyme S -0.0642738
PTMA prothymosin, alpha -0.0639344
PARP14 poly (ADP-ribose) polymerase family, member 14 -0.0603876
NPSR1 neuropeptide S receptor 1 -0.0592753
INTS6 integrator complex subunit 6 -0.059167
RAB7A RAB7A, member RAS oncogene family -0.0580015
RNF213 ring finger protein 213 -0.0576216
TMC5 transmembrane channel-like 5 -0.0576064
HCN1 hyperpolarization activated cyclic nucleotide gated potassium channel 1 -0.0573966
GCLC glutamate-cysteine ligase, catalytic subunit -0.0563912
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0550004
EXT1 exostosin glycosyltransferase 1 -0.0545937
XAF1 XIAP associated factor 1 -0.0544129
TPT1 tumor protein, translationally-controlled 1 -0.0525807
PERP PERP, TP53 apoptosis effector -0.050959
GMDS GDP-mannose 4,6-dehydratase -0.05077
PLSCR2 phospholipid scramblase 2 -0.0497058
PLSCR1 phospholipid scramblase 1 -0.0492167
AREG amphiregulin -0.0488247
PLA2G2A phospholipase A2, group IIA (platelets, synovial fluid) -0.0487868
LAMA4 laminin, alpha 4 -0.0478888
IFIT3 interferon-induced protein with tetratricopeptide repeats 3 -0.0471457
RSAD2 radical S-adenosyl methionine domain containing 2 -0.0467072
TSHZ2 teashirt zinc finger homeobox 2 -0.0461818
RABGAP1L RAB GTPase activating protein 1-like -0.0456275
LMO7 LIM domain 7 -0.044905
EGR1 early growth response 1 -0.0424428
LCN2 lipocalin 2 -0.0423497
TM4SF19 transmembrane 4 L six family member 19 -0.0423267
DDX60L DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like -0.0422525
MAML2 mastermind-like 2 (Drosophila) -0.0417777
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 -0.0416744
IGFBP3 insulin-like growth factor binding protein 3 -0.0415151
PMP22 peripheral myelin protein 22 -0.0396757
NT5C3A 5'-nucleotidase, cytosolic IIIA -0.0375739
ERBIN erbb2 interacting protein -0.0371464
CATSPERB catsper channel auxiliary subunit beta -0.0367376
ARHGAP26 Rho GTPase activating protein 26 -0.0353725
RPL35A ribosomal protein L35a -0.0340095
DDX60 DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 -0.0336927
NAALADL2 N-acetylated alpha-linked acidic dipeptidase-like 2 -0.0334991
ERN1 endoplasmic reticulum to nucleus signaling 1 -0.0325565
KPNB1 karyopherin (importin) beta 1 -0.0316196
FTH1 ferritin, heavy polypeptide 1 -0.0312
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.030982
ACTG1 actin gamma 1 -0.0309195
MAP7 microtubule-associated protein 7 -0.0301538
PITPNC1 phosphatidylinositol transfer protein, cytoplasmic 1 -0.02969
VMP1 vacuole membrane protein 1 -0.0296374
MUC20 mucin 20, cell surface associated -0.0294993
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0293232
POF1B premature ovarian failure, 1B -0.0293075
CYP3A5 cytochrome P450, family 3, subfamily A, polypeptide 5 -0.0288495
CUX1 cut-like homeobox 1 -0.028338
PARP9 poly (ADP-ribose) polymerase family, member 9 -0.0280017
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 -0.0279132
GULP1 GULP, engulfment adaptor PTB domain containing 1 -0.02789
FHIT fragile histidine triad -0.0277688
NFAT5 nuclear factor of activated T-cells 5, tonicity-responsive -0.0275165
SQSTM1 sequestosome 1 -0.0272304
GK glycerol kinase -0.0266665
RPS6 ribosomal protein S6 -0.0264304
SLC38A1 solute carrier family 38, member 1 -0.0262984
NABP1 nucleic acid binding protein 1 -0.0256303
MAP3K5 mitogen-activated protein kinase kinase kinase 5 -0.0250995
HMGB1 high mobility group box 1 -0.024859
ALCAM activated leukocyte cell adhesion molecule -0.0247969
POU2F2 POU class 2 homeobox 2 -0.0247871
LPP LIM domain containing preferred translocation partner in lipoma -0.0245552
YWHAB tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta -0.0244142
IFIH1 interferon induced with helicase C domain 1 -0.024122
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) -0.0240981
FRMD5 FERM domain containing 5 -0.0239858
BAIAP2L1 BAI1-associated protein 2-like 1 -0.0239218
B2M beta-2-microglobulin -0.0237638
ITGA6 integrin, alpha 6 -0.0236671
MCL1 myeloid cell leukemia 1 -0.0235716
SAMHD1 SAM domain and HD domain 1 -0.0234012
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0232266
IFI27 interferon, alpha-inducible protein 27 -0.0232027
LAP3 leucine aminopeptidase 3 -0.0231843
ZBTB20 zinc finger and BTB domain containing 20 -0.0231623
ZNFX1 zinc finger, NFX1-type containing 1 -0.0229781
DNAJC15 DnaJ (Hsp40) homolog, subfamily C, member 15 -0.0229777
SLC12A2 solute carrier family 12 (sodium/potassium/chloride transporter), member 2 -0.0226533
ETV6 ets variant 6 -0.0223859
RPL7L1 ribosomal protein L7-like 1 -0.0223129
UBAP2 ubiquitin associated protein 2 -0.0222587
EFNA5 ephrin-A5 -0.0220321
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) -0.0217385