| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in HS-578T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_HS-578T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.210568 |
| FN1 | fibronectin 1 | 0.199467 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.195132 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.140876 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.126034 |
| NDRG1 | N-myc downstream regulated 1 | 0.121919 |
| PLEC | plectin | 0.120599 |
| CADM1 | cell adhesion molecule 1 | 0.0951155 |
| LOC112694756 | uncharaterized LOC112694756 | 0.078949 |
| AHNAK | AHNAK nucleoprotein | 0.0630513 |
| COL5A1 | collagen, type V, alpha 1 | 0.0614432 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0600738 |
| CD44 | CD44 molecule (Indian blood group) | 0.0578811 |
| JARID2 | jumonji, AT rich interactive domain 2 | 0.0540851 |
| MTSS1 | metastasis suppressor 1 | 0.0534689 |
| RPL3 | ribosomal protein L3 | 0.0527719 |
| FLNA | filamin A, alpha | 0.0520229 |
| MYO10 | myosin X | 0.0517269 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0514357 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0508656 |
| VEGFA | vascular endothelial growth factor A | 0.05032 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0495004 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0480944 |
| CDH13 | cadherin 13 | 0.0479652 |
| NAV2 | neuron navigator 2 | 0.0477821 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0471801 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0467779 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0462214 |
| EGFR | epidermal growth factor receptor | 0.0423224 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0408862 |
| ARRDC3 | arrestin domain containing 3 | 0.0400664 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0395283 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.039474 |
| COL7A1 | collagen, type VII, alpha 1 | 0.0392333 |
| ECE1 | endothelin converting enzyme 1 | 0.0389047 |
| IER3 | immediate early response 3 | 0.0385911 |
| RUNX1 | runt-related transcription factor 1 | 0.0367887 |
| APP | amyloid beta (A4) precursor protein | 0.0364291 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0357413 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0354293 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0352954 |
| LOXL2 | lysyl oxidase-like 2 | 0.0331426 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0326403 |
| FAT1 | FAT atypical cadherin 1 | 0.0316712 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0314561 |
| MSN | moesin | 0.0312821 |
| H1-4 | H1.4 linker histone, cluster member | 0.0311939 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0307983 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0303015 |
| ENO1 | enolase 1, (alpha) | 0.0299811 |
| SEPTIN9 | septin 9 | 0.0296228 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0295473 |
| SMAD3 | SMAD family member 3 | 0.0292063 |
| JUN | jun proto-oncogene | 0.0288547 |
| TNS1 | tensin 1 | 0.0274183 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | 0.0272364 |
| SDC2 | syndecan 2 | 0.0269912 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0267975 |
| CLIC4 | chloride intracellular channel 4 | 0.0261064 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0257255 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0256584 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0252836 |
| HDAC9 | histone deacetylase 9 | 0.0248292 |
| SLC39A14 | solute carrier family 39 (zinc transporter), member 14 | 0.0245309 |
| ST3GAL1 | ST3 beta-galactoside alpha-2,3-sialyltransferase 1 | 0.0244674 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0242625 |
| FGFR1 | fibroblast growth factor receptor 1 | 0.0240333 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0240212 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0239407 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0238156 |
| STC2 | stanniocalcin 2 | 0.0234266 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0229103 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0228497 |
| PAG1 | phosphoprotein membrane anchor with glycosphingolipid microdomains 1 | 0.0223546 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0217186 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0212333 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0211494 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0209998 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0207965 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0207553 |
| ATXN1 | ataxin 1 | 0.0206434 |
| HDLBP | high density lipoprotein binding protein | 0.0206007 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0203587 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0198661 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.0197004 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0196043 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0195064 |
| IRF1 | interferon regulatory factor 1 | 0.0193705 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0192924 |
| MRTFA | myocardin related transcription factor A | 0.0191345 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0186996 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0186982 |
| RIPK4 | receptor-interacting serine-threonine kinase 4 | 0.018385 |
| KLF10 | Kruppel-like factor 10 | 0.0182835 |
| YEATS2 | YEATS domain containing 2 | 0.0179046 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0178597 |
| UBC | ubiquitin C | 0.0177483 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0177129 |
| TPI1 | triosephosphate isomerase 1 | 0.0173353 |
| AP2M1 | adaptor-related protein complex 2, mu 1 subunit | 0.0171891 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.192605 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.119505 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.114681 |
| MT2A | metallothionein 2A | -0.0938109 |
| TMSB10 | thymosin beta 10 | -0.0651694 |
| COL1A1 | collagen, type I, alpha 1 | -0.0629723 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0616603 |
| PTMA | prothymosin, alpha | -0.0611099 |
| STC1 | stanniocalcin 1 | -0.0598851 |
| COL1A2 | collagen, type I, alpha 2 | -0.0570883 |
| HMGA2 | high mobility group AT-hook 2 | -0.0546512 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0545824 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0506682 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0466488 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0448696 |
| ATP13A3 | ATPase type 13A3 | -0.0432286 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0404074 |
| WASF2 | WAS protein family, member 2 | -0.0397286 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0376792 |
| POSTN | periostin, osteoblast specific factor | -0.0367169 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0363389 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0359394 |
| RPS8 | ribosomal protein S8 | -0.035871 |
| ARFGAP3 | ADP-ribosylation factor GTPase activating protein 3 | -0.0349949 |
| FTL | ferritin, light polypeptide | -0.0347463 |
| GOLGA4 | golgin A4 | -0.0326625 |
| PFN1 | profilin 1 | -0.0326232 |
| CANX | calnexin | -0.0317005 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.030928 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.0301195 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0299746 |
| TRAM1 | translocation associated membrane protein 1 | -0.0299415 |
| RPS19 | ribosomal protein S19 | -0.0296795 |
| SMYD3 | SET and MYND domain containing 3 | -0.0294043 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0293834 |
| SRGN | serglycin | -0.0285035 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0274648 |
| TRPS1 | trichorhinophalangeal syndrome I | -0.0270364 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0264457 |
| AHI1 | Abelson helper integration site 1 | -0.0259373 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.025885 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0256447 |
| RPS3 | ribosomal protein S3 | -0.0255862 |
| RPL8 | ribosomal protein L8 | -0.0254439 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0250621 |
| TFG | TRK-fused gene | -0.0247668 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0247256 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0245405 |
| MYADM | myeloid-associated differentiation marker | -0.0244381 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0240973 |
| COG5 | component of oligomeric golgi complex 5 | -0.0240601 |
| SRP54 | signal recognition particle 54kDa | -0.0238928 |
| ITCH | itchy E3 ubiquitin protein ligase | -0.0237317 |
| MAP1B | microtubule-associated protein 1B | -0.0235037 |
| RPL32 | ribosomal protein L32 | -0.0230028 |
| SBF2 | SET binding factor 2 | -0.0225794 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0220655 |
| NF1 | neurofibromin 1 | -0.0220493 |
| EVI5 | ecotropic viral integration site 5 | -0.0220018 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0217412 |
| RPL35A | ribosomal protein L35a | -0.0215809 |
| TMEM263 | transmembrane protein 263 | -0.0213693 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.0210212 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0207561 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0207064 |
| PALLD | palladin, cytoskeletal associated protein | -0.0206161 |
| RPS13 | ribosomal protein S13 | -0.0206154 |
| B2M | beta-2-microglobulin | -0.0205559 |
| S100A6 | S100 calcium binding protein A6 | -0.0201129 |
| TMEM41B | transmembrane protein 41B | -0.0197654 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.019383 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0193471 |
| JMJD1C | jumonji domain containing 1C | -0.0193405 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.0191919 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0191393 |
| MTDH | metadherin | -0.0188853 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.0186746 |
| NKAIN3 | Na+/K+ transporting ATPase interacting 3 | -0.0186624 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.018649 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0185675 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0185353 |
| RYK | receptor-like tyrosine kinase | -0.0183405 |
| RPL26 | ribosomal protein L26 | -0.0183045 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | -0.0181707 |
| ATM | ATM serine/threonine kinase | -0.0179635 |
| RASA2 | RAS p21 protein activator 2 | -0.0179301 |
| PRRC1 | proline-rich coiled-coil 1 | -0.0177887 |
| PERP | PERP, TP53 apoptosis effector | -0.0177622 |
| RRBP1 | ribosome binding protein 1 | -0.0177348 |
| HMCN1 | hemicentin 1 | -0.0176257 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.0175632 |
| RBM39 | RNA binding motif protein 39 | -0.0175172 |
| GOLGB1 | golgin B1 | -0.017511 |
| SEPTIN7 | septin 7 | -0.017283 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0171216 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0170478 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0169779 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.0169401 |
| PCBP2 | poly(rC) binding protein 2 | -0.0166652 |
| KCTD9 | potassium channel tetramerization domain containing 9 | -0.0165072 |
