| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in HepG2/C3A cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_HepG2/C3A drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | 0.373194 |
| APOB | apolipoprotein B | 0.27067 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.12627 |
| C3 | complement component 3 | 0.11364 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.1064 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0983712 |
| GPC3 | glypican 3 | 0.0921212 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0808972 |
| FN1 | fibronectin 1 | 0.0804225 |
| RPL3 | ribosomal protein L3 | 0.0767257 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0731187 |
| DSPP | dentin sialophosphoprotein | 0.0726265 |
| SDC4 | syndecan 4 | 0.0713464 |
| ENO1 | enolase 1, (alpha) | 0.070239 |
| FBF1 | Fas (TNFRSF6) binding factor 1 | 0.0610292 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0594345 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.056756 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | 0.0556823 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0534005 |
| ACSL4 | acyl-CoA synthetase long-chain family member 4 | 0.0502123 |
| A2M | alpha-2-macroglobulin | 0.0497734 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0497091 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.047812 |
| TF | transferrin | 0.0471243 |
| RPS6 | ribosomal protein S6 | 0.0447476 |
| SFTPA2 | surfactant protein A2 | 0.044023 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0438045 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0434297 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0434262 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0432268 |
| CPE | carboxypeptidase E | 0.0410848 |
| AFDN | afadin, adherens junction formation factor | 0.041073 |
| GPAM | glycerol-3-phosphate acyltransferase, mitochondrial | 0.0402488 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0396232 |
| LYZ | lysozyme | 0.0390955 |
| PLEC | plectin | 0.0387482 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0386936 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.037265 |
| MRTFA | myocardin related transcription factor A | 0.0370147 |
| TPM4 | tropomyosin 4 | 0.03589 |
| PEG3 | paternally expressed 3 | 0.0358875 |
| MATR3 | matrin 3 | 0.0357673 |
| ENAH | enabled homolog (Drosophila) | 0.0350937 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0346881 |
| BCL2L1 | BCL2-like 1 | 0.0339126 |
| RPLP0 | ribosomal protein, large, P0 | 0.0328246 |
| SNX9 | sorting nexin 9 | 0.032003 |
| RPL9 | ribosomal protein L9 | 0.0317794 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0316853 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0316233 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | 0.0315794 |
| DSTN | destrin (actin depolymerizing factor) | 0.0314044 |
| ARHGEF18 | Rho/Rac guanine nucleotide exchange factor (GEF) 18 | 0.0309551 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.0308213 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0301068 |
| ACTN4 | actinin, alpha 4 | 0.0300796 |
| SETD5 | SET domain containing 5 | 0.0299499 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0298024 |
| CCL20 | chemokine (C-C motif) ligand 20 | 0.029473 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0292056 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0289626 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0283109 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.028211 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0281198 |
| RTN4 | reticulon 4 | 0.0280905 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0280476 |
| KIF5B | kinesin family member 5B | 0.027977 |
| CFB | complement factor B | 0.0278773 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0277973 |
| WDR45B | WD repeat domain 45B | 0.0277711 |
| UBC | ubiquitin C | 0.0277604 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0275564 |
| PERP | PERP, TP53 apoptosis effector | 0.0273624 |
| ECE1 | endothelin converting enzyme 1 | 0.0273309 |
| TGFBR2 | transforming growth factor, beta receptor II (70/80kDa) | 0.0273168 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0272479 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0268392 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0264162 |
| SVIL | supervillin | 0.026203 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | 0.0260501 |
| LYPLA1 | lysophospholipase I | 0.025863 |
| YAP1 | Yes-associated protein 1 | 0.0258364 |
| RPL35A | ribosomal protein L35a | 0.0257668 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.0256888 |
| IFNGR1 | interferon gamma receptor 1 | 0.025631 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0256242 |
| UBE2B | ubiquitin-conjugating enzyme E2B | 0.0255501 |
| UBE2D2 | ubiquitin-conjugating enzyme E2D 2 | 0.0253467 |
| DEK | DEK proto-oncogene | 0.0252752 |
| PHIP | pleckstrin homology domain interacting protein | 0.0250509 |
| RPLP1 | ribosomal protein, large, P1 | 0.0248056 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.0247214 |
| NDUFV2 | NADH dehydrogenase (ubiquinone) flavoprotein 2, 24kDa | 0.0246721 |
| ADAR | adenosine deaminase, RNA-specific | 0.0245942 |
| ZFR | zinc finger RNA binding protein | 0.0245495 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0242421 |
| LSM14A | LSM14A, SCD6 homolog A (S. cerevisiae) | 0.0242204 |
| OSMR | oncostatin M receptor | 0.0241657 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0241402 |
| FAT1 | FAT atypical cadherin 1 | 0.0241324 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.22056 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.123909 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0942603 |
| MT2A | metallothionein 2A | -0.0818354 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0776326 |
| EHBP1 | EH domain binding protein 1 | -0.0765891 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0742835 |
| ASPH | aspartate beta-hydroxylase | -0.0669145 |
| ATXN1 | ataxin 1 | -0.0667164 |
| RPL37A | ribosomal protein L37a | -0.0665128 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0658369 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0643219 |
| INTS6 | integrator complex subunit 6 | -0.0617325 |
| GPC6 | glypican 6 | -0.0606092 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0605422 |
| DTNA | dystrobrevin, alpha | -0.0604567 |
| RPS3 | ribosomal protein S3 | -0.0582653 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0580218 |
| APOA2 | apolipoprotein A-II | -0.056835 |
| RPL31 | ribosomal protein L31 | -0.0491761 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0456389 |
| VEGFA | vascular endothelial growth factor A | -0.0415439 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0412171 |
| GK | glycerol kinase | -0.0409787 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0408898 |
| APOC1 | apolipoprotein C-I | -0.0372607 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0370732 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0348932 |
| HDAC4 | histone deacetylase 4 | -0.0339359 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.0335645 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0331483 |
| DST | dystonin | -0.0324259 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0312361 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0309895 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0307933 |
| CHST15 | carbohydrate (N-acetylgalactosamine 4-sulfate 6-O) sulfotransferase 15 | -0.0307545 |
| RPS12 | ribosomal protein S12 | -0.0305093 |
| MALRD1 | MAM and LDL receptor class A domain containing 1 | -0.0304393 |
| RPS17 | ribosomal protein S17 | -0.0302485 |
| NABP1 | nucleic acid binding protein 1 | -0.0302271 |
| RUNX1 | runt-related transcription factor 1 | -0.0298381 |
| CP | ceruloplasmin (ferroxidase) | -0.0293838 |
| TNS1 | tensin 1 | -0.0277661 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0276542 |
| NPAS2 | neuronal PAS domain protein 2 | -0.027654 |
| MBNL2 | muscleblind-like splicing regulator 2 | -0.0269673 |
| SPIRE1 | spire-type actin nucleation factor 1 | -0.0267633 |
| RIGI | RNA sensor RIG-I | -0.0263444 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | -0.0262187 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0259861 |
| NDRG1 | N-myc downstream regulated 1 | -0.0257398 |
| FAM13A | family with sequence similarity 13, member A | -0.0253341 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | -0.0253158 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0249986 |
| RPL13A | ribosomal protein L13a | -0.0244315 |
| RPS13 | ribosomal protein S13 | -0.0242502 |
| RBM39 | RNA binding motif protein 39 | -0.0238179 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | -0.023813 |
| ZRANB1 | zinc finger, RAN-binding domain containing 1 | -0.0235827 |
| GOLGB1 | golgin B1 | -0.023362 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0233141 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.023049 |
| FKTN | fukutin | -0.0229218 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0227008 |
| RPS19 | ribosomal protein S19 | -0.0226665 |
| ATP10A | ATPase, class V, type 10A | -0.0221795 |
| RPL7A | ribosomal protein L7a | -0.0221118 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.0220564 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | -0.0218408 |
| LRMDA | leucine rich melanocyte differentiation associated | -0.0218324 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0216095 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0215185 |
| FAM53C | family with sequence similarity 53, member C | -0.0214835 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0214047 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0214035 |
| ETFB | electron-transfer-flavoprotein, beta polypeptide | -0.0212765 |
| WWC2 | WW and C2 domain containing 2 | -0.0212279 |
| PEAK1 | pseudopodium-enriched atypical kinase 1 | -0.0210762 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0206379 |
| STK17A | serine/threonine kinase 17a | -0.0198574 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | -0.0197407 |
| PRDM2 | PR domain containing 2, with ZNF domain | -0.0196841 |
| ARHGAP21 | Rho GTPase activating protein 21 | -0.0196349 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0194858 |
| STC2 | stanniocalcin 2 | -0.0194112 |
| RPS10 | ribosomal protein S10 | -0.019345 |
| PCCA | propionyl CoA carboxylase, alpha polypeptide | -0.0192127 |
| SLC9A1 | solute carrier family 9, subfamily A (NHE1, cation proton antiporter 1), member 1 | -0.019181 |
| RPS6KA3 | ribosomal protein S6 kinase, 90kDa, polypeptide 3 | -0.0189006 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0187969 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | -0.0186555 |
| SERINC5 | serine incorporator 5 | -0.0185272 |
| RPLP2 | ribosomal protein, large, P2 | -0.0184703 |
| PTPRG | protein tyrosine phosphatase, receptor type, G | -0.018452 |
| BBX | bobby sox homolog (Drosophila) | -0.0183048 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0182689 |
| UBE2D1 | ubiquitin-conjugating enzyme E2D 1 | -0.0182161 |
| ABHD3 | abhydrolase domain containing 3 | -0.0182141 |
| MYO6 | myosin VI | -0.0181129 |
| ANO6 | anoctamin 6 | -0.0179352 |
