| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Decitabine_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.209492 |
| LOC112694756 | uncharaterized LOC112694756 | 0.166363 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.162866 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.160577 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.134123 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.119958 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.10256 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.102485 |
| TMSB4X | thymosin beta 4, X-linked | 0.0934688 |
| AHNAK | AHNAK nucleoprotein | 0.0927925 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0898452 |
| TXNRD1 | thioredoxin reductase 1 | 0.0835683 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0806117 |
| RPL3 | ribosomal protein L3 | 0.0750668 |
| POTEF | POTE ankyrin domain family, member F | 0.070607 |
| PGK1 | phosphoglycerate kinase 1 | 0.067935 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0668603 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0658823 |
| RAI1 | retinoic acid induced 1 | 0.060891 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0603751 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0588542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0578238 |
| SPAG9 | sperm associated antigen 9 | 0.0576112 |
| LDHA | lactate dehydrogenase A | 0.0563918 |
| CANX | calnexin | 0.0558868 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0541838 |
| CENPF | centromere protein F, 350/400kDa | 0.0541645 |
| EZR | ezrin | 0.0540061 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0539421 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0519037 |
| APP | amyloid beta (A4) precursor protein | 0.0517059 |
| UBC | ubiquitin C | 0.04929 |
| MKI67 | marker of proliferation Ki-67 | 0.0484053 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0471709 |
| ARRDC3 | arrestin domain containing 3 | 0.04598 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0456646 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0450447 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0441152 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.044067 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0431353 |
| TRIP12 | thyroid hormone receptor interactor 12 | 0.0424641 |
| RTN4 | reticulon 4 | 0.0423688 |
| PKM | pyruvate kinase, muscle | 0.0419285 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0417843 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0414486 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0414167 |
| HDLBP | high density lipoprotein binding protein | 0.0413225 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0408735 |
| ENO1 | enolase 1, (alpha) | 0.0398155 |
| SET | SET nuclear proto-oncogene | 0.0397001 |
| NUP58 | nucleoporin 58 | 0.0396626 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0394109 |
| EREG | epiregulin | 0.0392823 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0388878 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0388066 |
| MATR3 | matrin 3 | 0.0386991 |
| TPI1 | triosephosphate isomerase 1 | 0.038219 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0380422 |
| OGA | O-GlcNAcase | 0.0379703 |
| WDR45B | WD repeat domain 45B | 0.0378937 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0366886 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0360932 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0357387 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0356881 |
| TOP1 | topoisomerase (DNA) I | 0.035565 |
| VIM | vimentin | 0.035388 |
| FLNB | filamin B, beta | 0.0351934 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0348925 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0347991 |
| XPO1 | exportin 1 | 0.0347128 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0345113 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0343781 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.033611 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0335866 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0331284 |
| PLK2 | polo-like kinase 2 | 0.0323227 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0321047 |
| UAP1 | UDP-N-acetylglucosamine pyrophosphorylase 1 | 0.0320562 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0318893 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0313499 |
| KLF6 | Kruppel-like factor 6 | 0.031143 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0310409 |
| PLEC | plectin | 0.0310176 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0308182 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.03014 |
| ANLN | anillin, actin binding protein | 0.02981 |
| EMP1 | epithelial membrane protein 1 | 0.0297791 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0297603 |
| GOLGA4 | golgin A4 | 0.0297358 |
| IGF2BP3 | insulin-like growth factor 2 mRNA binding protein 3 | 0.0296985 |
| SEPTIN7 | septin 7 | 0.0296917 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0296005 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0295759 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0295347 |
| ADAR | adenosine deaminase, RNA-specific | 0.0291612 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0290875 |
| ILF3 | interleukin enhancer binding factor 3, 90kDa | 0.0288373 |
| YBX1 | Y box binding protein 1 | 0.0286777 |
| TMEM123 | transmembrane protein 123 | 0.028013 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0278935 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TP63 | tumor protein p63 | -0.183531 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.122576 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.115086 |
| CADM2 | cell adhesion molecule 2 | -0.105506 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0914168 |
| ZDHHC14 | zinc finger, DHHC-type containing 14 | -0.0735189 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0710745 |
| MT2A | metallothionein 2A | -0.0653661 |
| TNS3 | tensin 3 | -0.0632667 |
| DST | dystonin | -0.0615542 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.060158 |
| EHBP1 | EH domain binding protein 1 | -0.0585586 |
| TMSB10 | thymosin beta 10 | -0.0569897 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0560646 |
| CSMD3 | CUB and Sushi multiple domains 3 | -0.0558374 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0535731 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0515417 |
| PDE10A | phosphodiesterase 10A | -0.0476549 |
| EPHA4 | EPH receptor A4 | -0.0473794 |
| EFNA5 | ephrin-A5 | -0.0450116 |
| RPS19 | ribosomal protein S19 | -0.0447921 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0428146 |
| SP100 | SP100 nuclear antigen | -0.0427885 |
| RPL37A | ribosomal protein L37a | -0.0426569 |
| PRELID2 | PRELI domain containing 2 | -0.0424804 |
| EXOC4 | exocyst complex component 4 | -0.042028 |
| HDAC9 | histone deacetylase 9 | -0.0409843 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | -0.0399066 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.03961 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0388308 |
| HLA-B | major histocompatibility complex, class I, B | -0.0386887 |
| RPS8 | ribosomal protein S8 | -0.0374687 |
| NPAS2 | neuronal PAS domain protein 2 | -0.0363559 |
| RIGI | RNA sensor RIG-I | -0.0361128 |
| RAD51B | RAD51 paralog B | -0.0346475 |
| FTL | ferritin, light polypeptide | -0.0342127 |
| RPL36 | ribosomal protein L36 | -0.0340933 |
| RPL31 | ribosomal protein L31 | -0.0339536 |
| PLSCR1 | phospholipid scramblase 1 | -0.0324142 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0322964 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0307851 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0300918 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0294223 |
| RPLP2 | ribosomal protein, large, P2 | -0.0290788 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0289105 |
| EGFR | epidermal growth factor receptor | -0.0288318 |
| CD44 | CD44 molecule (Indian blood group) | -0.0286972 |
| INTS6 | integrator complex subunit 6 | -0.0276643 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0272867 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0271996 |
| RPS29 | ribosomal protein S29 | -0.0270467 |
| DPH6 | diphthamine biosynthesis 6 | -0.0268542 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0268174 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0265059 |
| WDR27 | WD repeat domain 27 | -0.0252143 |
| RPL26 | ribosomal protein L26 | -0.0251623 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0247578 |
| RPS12 | ribosomal protein S12 | -0.0246215 |
| PTMA | prothymosin, alpha | -0.0241771 |
| RNF213 | ring finger protein 213 | -0.0239156 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0237754 |
| RPS3 | ribosomal protein S3 | -0.0236022 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0233287 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0232152 |
| SMYD3 | SET and MYND domain containing 3 | -0.0230145 |
| RPL35A | ribosomal protein L35a | -0.0226817 |
| AEBP2 | AE binding protein 2 | -0.0225127 |
| NEK10 | NIMA-related kinase 10 | -0.0223965 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0220895 |
| SLCO1B3-SLCO1B7 | SLCO1B3-SLCO1B7 readthrough | -0.0220567 |
| DENND1A | DENN/MADD domain containing 1A | -0.0218072 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0216383 |
| DNER | delta/notch-like EGF repeat containing | -0.0213208 |
| OGDH | oxoglutarate (alpha-ketoglutarate) dehydrogenase (lipoamide) | -0.0211922 |
| RPS23 | ribosomal protein S23 | -0.0211001 |
| GNGT1 | guanine nucleotide binding protein (G protein), gamma transducing activity polypeptide 1 | -0.0208627 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0206788 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0203367 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0203217 |
| TPRG1 | tumor protein p63 regulated 1 | -0.020277 |
| RUNX1 | runt-related transcription factor 1 | -0.0202692 |
| PMP22 | peripheral myelin protein 22 | -0.0202473 |
| CMIP | c-Maf inducing protein | -0.0202427 |
| MYO9A | myosin IXA | -0.0202366 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0201832 |
| PRG2 | proteoglycan 2, bone marrow (natural killer cell activator, eosinophil granule major basic protein) | -0.0192909 |
| CUX1 | cut-like homeobox 1 | -0.0192731 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0190179 |
| RPL28 | ribosomal protein L28 | -0.0183408 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0183277 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0183266 |
| VEGFC | vascular endothelial growth factor C | -0.0182995 |
| SLCO1B3 | solute carrier organic anion transporter family, member 1B3 | -0.018036 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.01793 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0178489 |
| SLC39A10 | solute carrier family 39 (zinc transporter), member 10 | -0.0177111 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.017627 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0175693 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0172774 |
| TGM2 | transglutaminase 2 | -0.0171478 |
