| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.287986 |
| LOC112694756 | uncharaterized LOC112694756 | 0.205808 |
| TXNRD1 | thioredoxin reductase 1 | 0.15836 |
| PLEC | plectin | 0.113191 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.111824 |
| LAMC2 | laminin, gamma 2 | 0.101916 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0801341 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0796783 |
| HDLBP | high density lipoprotein binding protein | 0.0760545 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0759623 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0732471 |
| SMAD3 | SMAD family member 3 | 0.0671419 |
| H1-0 | H1.0 linker histone | 0.0629172 |
| LAMB3 | laminin, beta 3 | 0.0584038 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0571921 |
| PGK1 | phosphoglycerate kinase 1 | 0.0553385 |
| FAM13A | family with sequence similarity 13, member A | 0.0532251 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0530691 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0521988 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0518315 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0490697 |
| AHNAK | AHNAK nucleoprotein | 0.0479042 |
| RPL3 | ribosomal protein L3 | 0.0465645 |
| ARRDC3 | arrestin domain containing 3 | 0.0458511 |
| TOP1 | topoisomerase (DNA) I | 0.0456202 |
| CES1 | carboxylesterase 1 | 0.0441706 |
| ASPH | aspartate beta-hydroxylase | 0.042021 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.041462 |
| OGA | O-GlcNAcase | 0.0406527 |
| UBC | ubiquitin C | 0.0402577 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0400297 |
| STC1 | stanniocalcin 1 | 0.0399407 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0394345 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0394305 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0394234 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0380954 |
| LANCL2 | LanC lantibiotic synthetase component C-like 2 (bacterial) | 0.0377867 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0373726 |
| WDR45B | WD repeat domain 45B | 0.0373045 |
| PPFIA1 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 | 0.0372285 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | 0.0368941 |
| NGLY1 | N-glycanase 1 | 0.0368539 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | 0.0359664 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.03566 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0348897 |
| MARK3 | MAP/microtubule affinity-regulating kinase 3 | 0.03486 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0347694 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.0343006 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0337904 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0336175 |
| ARFGEF2 | ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited) | 0.0335784 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.032672 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0325326 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0324746 |
| ANKRD11 | ankyrin repeat domain 11 | 0.032301 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0320664 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0312465 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0311104 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0309888 |
| LMO7 | LIM domain 7 | 0.0309503 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | 0.0308555 |
| TPD52 | tumor protein D52 | 0.0304769 |
| CANX | calnexin | 0.0302758 |
| MKI67 | marker of proliferation Ki-67 | 0.0301828 |
| ENO1 | enolase 1, (alpha) | 0.030061 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0298386 |
| APP | amyloid beta (A4) precursor protein | 0.029645 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0292009 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | 0.029198 |
| BIRC3 | baculoviral IAP repeat containing 3 | 0.0291599 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | 0.0286813 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0280581 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.0274616 |
| GRAMD1B | GRAM domain containing 1B | 0.0274135 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0268193 |
| ACTR2 | ARP2 actin-related protein 2 homolog (yeast) | 0.0266971 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0266738 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0266097 |
| DSPP | dentin sialophosphoprotein | 0.026585 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | 0.0265302 |
| CTTN | cortactin | 0.0264099 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0263686 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0263239 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0262833 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | 0.0262543 |
| NCKAP1 | NCK-associated protein 1 | 0.0262096 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0261868 |
| SLMAP | sarcolemma associated protein | 0.0260088 |
| HYOU1 | hypoxia up-regulated 1 | 0.0257073 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0256374 |
| CPE | carboxypeptidase E | 0.0255807 |
| CAB39 | calcium binding protein 39 | 0.0254075 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0253668 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0253275 |
| RNF149 | ring finger protein 149 | 0.0253168 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0250893 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0250871 |
| SDC4 | syndecan 4 | 0.0250753 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0249504 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0247109 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.161167 |
| EGR1 | early growth response 1 | -0.096271 |
| TMSB10 | thymosin beta 10 | -0.0870005 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0821084 |
| MT2A | metallothionein 2A | -0.0595492 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0556547 |
| NABP1 | nucleic acid binding protein 1 | -0.0549452 |
| RPS3 | ribosomal protein S3 | -0.0522894 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0508092 |
| INTS6 | integrator complex subunit 6 | -0.0504597 |
| EGFR | epidermal growth factor receptor | -0.0462145 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0415056 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.040119 |
| RPL37A | ribosomal protein L37a | -0.0393732 |
| RPS25 | ribosomal protein S25 | -0.0334923 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.032525 |
| NSUN6 | NOP2/Sun domain family, member 6 | -0.0308517 |
| RPS12 | ribosomal protein S12 | -0.029751 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0291916 |
| RPL31 | ribosomal protein L31 | -0.0277926 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | -0.0273521 |
| VMP1 | vacuole membrane protein 1 | -0.0273484 |
| MYO1E | myosin IE | -0.027169 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0268075 |
| FTL | ferritin, light polypeptide | -0.0267991 |
| HOMER1 | homer scaffolding protein 1 | -0.0267454 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0262176 |
| RPS23 | ribosomal protein S23 | -0.0257351 |
| RPLP2 | ribosomal protein, large, P2 | -0.0244585 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0244322 |
| SLTM | SAFB-like, transcription modulator | -0.0242969 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0242264 |
| VCL | vinculin | -0.0238404 |
| RPS19 | ribosomal protein S19 | -0.0237755 |
| RPS29 | ribosomal protein S29 | -0.0228097 |
| S100P | S100 calcium binding protein P | -0.02268 |
| CCNL1 | cyclin L1 | -0.0212864 |
| NR4A3 | nuclear receptor subfamily 4, group A, member 3 | -0.0212355 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | -0.0208182 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0207727 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0204796 |
| ENO2 | enolase 2 (gamma, neuronal) | -0.0203917 |
| TRAPPC9 | trafficking protein particle complex 9 | -0.0203212 |
| ADAM32 | ADAM metallopeptidase domain 32 | -0.0200923 |
| RPS17 | ribosomal protein S17 | -0.0196169 |
| TES | testin LIM domain protein | -0.0195354 |
| PIK3R3 | phosphoinositide-3-kinase, regulatory subunit 3 (gamma) | -0.0190129 |
| S100A10 | S100 calcium binding protein A10 | -0.0189264 |
| RPL19 | ribosomal protein L19 | -0.0189153 |
| NBEAL1 | neurobeachin-like 1 | -0.0188285 |
| MCTP1 | multiple C2 domains, transmembrane 1 | -0.0186688 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0183236 |
| RPS13 | ribosomal protein S13 | -0.0182989 |
| RPS11 | ribosomal protein S11 | -0.0181186 |
| ANKRD37 | ankyrin repeat domain 37 | -0.0173601 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0173234 |
| ARF4 | ADP-ribosylation factor 4 | -0.0172535 |
| OXSR1 | oxidative stress responsive 1 | -0.0166664 |
| SIK3 | SIK family kinase 3 | -0.016493 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0163211 |
| PFN1 | profilin 1 | -0.0162845 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | -0.0161107 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0160742 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0155278 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0154538 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0154538 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0154131 |
| RPL5 | ribosomal protein L5 | -0.0153755 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0151318 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0150973 |
| VEGFC | vascular endothelial growth factor C | -0.0149722 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0148018 |
| ANXA1 | annexin A1 | -0.0142255 |
| OCLN | occludin | -0.0140284 |
| HMGA1 | high mobility group AT-hook 1 | -0.0140163 |
| RPS15 | ribosomal protein S15 | -0.0140094 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0138392 |
| RPS14 | ribosomal protein S14 | -0.0138291 |
| EPAS1 | endothelial PAS domain protein 1 | -0.013727 |
| RPL30 | ribosomal protein L30 | -0.0135584 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.013516 |
| RPL36 | ribosomal protein L36 | -0.0132642 |
| PTEN | phosphatase and tensin homolog | -0.0132622 |
| MTHFD2L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2-like | -0.0132357 |
| ATF4 | activating transcription factor 4 | -0.0131951 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0130771 |
| RPS8 | ribosomal protein S8 | -0.0129573 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0127124 |
| KRT86 | keratin 86, type II | -0.0126337 |
| ARL5B | ADP-ribosylation factor-like 5B | -0.0125125 |
| MAP3K13 | mitogen-activated protein kinase kinase kinase 13 | -0.0122108 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.012137 |
| MIPOL1 | mirror-image polydactyly 1 | -0.0121363 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0121041 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.012009 |
| AHR | aryl hydrocarbon receptor | -0.0120039 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | -0.0119109 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0118944 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0118696 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.01185 |
