| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H1792 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Decitabine_NCI-H1792 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.105748 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0830926 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0730417 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.070719 |
| RPL3 | ribosomal protein L3 | 0.0702509 |
| OS9 | osteosarcoma amplified 9, endoplasmic reticulum lectin | 0.0680339 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.064145 |
| SMAD3 | SMAD family member 3 | 0.0631476 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0578695 |
| AHNAK | AHNAK nucleoprotein | 0.0575963 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0508629 |
| APP | amyloid beta (A4) precursor protein | 0.0503573 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0483859 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0466634 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0464944 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0449936 |
| SEPTIN9 | septin 9 | 0.0437716 |
| ENO1 | enolase 1, (alpha) | 0.0430343 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0419832 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.041773 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0393225 |
| HDLBP | high density lipoprotein binding protein | 0.0389842 |
| FLNB | filamin B, beta | 0.0378356 |
| TMSB4X | thymosin beta 4, X-linked | 0.0369112 |
| RPL4 | ribosomal protein L4 | 0.0368515 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0348471 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0341871 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0338827 |
| PRELID2 | PRELI domain containing 2 | 0.0334108 |
| OGA | O-GlcNAcase | 0.0331861 |
| USP34 | ubiquitin specific peptidase 34 | 0.0323779 |
| CEP250 | centrosomal protein 250kDa | 0.0322548 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0321201 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0307975 |
| MCL1 | myeloid cell leukemia 1 | 0.0301533 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0297549 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0296047 |
| NAV2 | neuron navigator 2 | 0.0294764 |
| PFKP | phosphofructokinase, platelet | 0.0291201 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0289827 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0289443 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0287155 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0280039 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0280002 |
| MARS1 | methionyl-tRNA synthetase 1 | 0.0279536 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0278739 |
| WDR45B | WD repeat domain 45B | 0.0276108 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0275991 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.027012 |
| ARRDC3 | arrestin domain containing 3 | 0.0270025 |
| SUN1 | Sad1 and UNC84 domain containing 1 | 0.0268418 |
| FLNA | filamin A, alpha | 0.0267102 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0266877 |
| PKM | pyruvate kinase, muscle | 0.0266093 |
| PGK1 | phosphoglycerate kinase 1 | 0.0265535 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0265241 |
| ACTN4 | actinin, alpha 4 | 0.0263124 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0258902 |
| PTP4A2 | protein tyrosine phosphatase type IVA, member 2 | 0.0252977 |
| RPS24 | ribosomal protein S24 | 0.0250978 |
| EIF3B | eukaryotic translation initiation factor 3, subunit B | 0.0249964 |
| FAM20C | family with sequence similarity 20, member C | 0.0249401 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0245866 |
| TPI1 | triosephosphate isomerase 1 | 0.0243449 |
| IFI6 | interferon, alpha-inducible protein 6 | 0.0241347 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0238397 |
| PLEC | plectin | 0.0238188 |
| MSN | moesin | 0.0236642 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0236207 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0234196 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0230933 |
| TXNRD1 | thioredoxin reductase 1 | 0.0228369 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0227982 |
| RPL14 | ribosomal protein L14 | 0.0225342 |
| ANGPTL4 | angiopoietin-like 4 | 0.022348 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0222779 |
| SERINC1 | serine incorporator 1 | 0.0222061 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0221253 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0221196 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.022102 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0219192 |
| SEMA4B | sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B | 0.0218046 |
| GPAT3 | glycerol-3-phosphate acyltransferase 3 | 0.0213527 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0212315 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0207047 |
| MLPH | melanophilin | 0.0206623 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | 0.0206291 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.020624 |
| HLA-B | major histocompatibility complex, class I, B | 0.0203914 |
| LAMB3 | laminin, beta 3 | 0.0203866 |
| RPS11 | ribosomal protein S11 | 0.0202616 |
| GYS1 | glycogen synthase 1 (muscle) | 0.0200878 |
| RHOA | ras homolog family member A | 0.0200792 |
| ECE1 | endothelin converting enzyme 1 | 0.0198584 |
| BIRC2 | baculoviral IAP repeat containing 2 | 0.0197908 |
| RAD51B | RAD51 paralog B | 0.0197213 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0194962 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.01947 |
| OPTN | optineurin | 0.0194656 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0194352 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.125569 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.103035 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0857764 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0825834 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0819987 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0804118 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0711184 |
| TMSB10 | thymosin beta 10 | -0.0684325 |
| FTL | ferritin, light polypeptide | -0.0602869 |
| MT2A | metallothionein 2A | -0.0545722 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.0529944 |
| NRG1 | neuregulin 1 | -0.0513786 |
| MEF2A | myocyte enhancer factor 2A | -0.0509407 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0506167 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0483497 |
| PCBP2 | poly(rC) binding protein 2 | -0.047542 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0467498 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0443504 |
| EGR1 | early growth response 1 | -0.0433159 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0428617 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0413782 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.040202 |
| PFN1 | profilin 1 | -0.0399527 |
| LOX | lysyl oxidase | -0.0393639 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0387479 |
| NDRG1 | N-myc downstream regulated 1 | -0.0372379 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.036896 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0367094 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.036516 |
| RBM39 | RNA binding motif protein 39 | -0.0361898 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0360443 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0346717 |
| MRPS6 | mitochondrial ribosomal protein S6 | -0.034501 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0333456 |
| GPC6 | glypican 6 | -0.0325584 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0309236 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | -0.0308073 |
| BLZF1 | basic leucine zipper nuclear factor 1 | -0.0303113 |
| HMGA1 | high mobility group AT-hook 1 | -0.0302029 |
| PTGS2 | prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) | -0.0301668 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0294947 |
| SRP54 | signal recognition particle 54kDa | -0.0293788 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0291524 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0289374 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0288071 |
| GLCCI1 | glucocorticoid induced 1 | -0.0283102 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | -0.0276315 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0265143 |
| MBNL1 | muscleblind-like splicing regulator 1 | -0.0264461 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0264108 |
| RPS19 | ribosomal protein S19 | -0.0261469 |
| STC1 | stanniocalcin 1 | -0.0259454 |
| ARF4 | ADP-ribosylation factor 4 | -0.0255469 |
| AADAC | arylacetamide deacetylase | -0.0247255 |
| NF1 | neurofibromin 1 | -0.0244594 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0239815 |
| TENT5A | terminal nucleotidyltransferase 5A | -0.0238073 |
| NTN4 | netrin 4 | -0.0235697 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0235131 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.023241 |
| VEGFC | vascular endothelial growth factor C | -0.0230274 |
| MYADM | myeloid-associated differentiation marker | -0.02292 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0225583 |
| RPL32 | ribosomal protein L32 | -0.0221185 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0220646 |
| MORF4L2 | mortality factor 4 like 2 | -0.0219414 |
| RPL18 | ribosomal protein L18 | -0.0216375 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.0216304 |
| VMP1 | vacuole membrane protein 1 | -0.0215031 |
| SEC24A | SEC24 family member A | -0.0213655 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0213145 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0211714 |
| MYC | v-myc avian myelocytomatosis viral oncogene homolog | -0.0209613 |
| GREB1L | growth regulation by estrogen in breast cancer-like | -0.0207242 |
| SSBP2 | single-stranded DNA binding protein 2 | -0.0206016 |
| SYAP1 | synapse associated protein 1 | -0.0205891 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.020544 |
| GLIS3 | GLIS family zinc finger 3 | -0.0203814 |
| TGFB1 | transforming growth factor, beta 1 | -0.0200889 |
| HMGA2 | high mobility group AT-hook 2 | -0.0200755 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0198026 |
| VIM | vimentin | -0.0197257 |
| PHF21A | PHD finger protein 21A | -0.0195682 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0195619 |
| GOLGA4 | golgin A4 | -0.0195536 |
| CDK2AP2 | cyclin-dependent kinase 2 associated protein 2 | -0.0194929 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0193807 |
| NLK | nemo-like kinase | -0.019234 |
| PRR16 | proline rich 16 | -0.0191756 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0190574 |
| RAB5A | RAB5A, member RAS oncogene family | -0.019003 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0188551 |
| DNER | delta/notch-like EGF repeat containing | -0.0185579 |
| CCDC88A | coiled-coil domain containing 88A | -0.0185004 |
| RND3 | Rho family GTPase 3 | -0.018494 |
| VRK2 | vaccinia related kinase 2 | -0.018408 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0183827 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | -0.0182819 |
| EXOC6B | exocyst complex component 6B | -0.0180415 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0179752 |