| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.150168 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.102226 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0945541 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.0901633 |
| RPL3 | ribosomal protein L3 | 0.0785311 |
| TPM3 | tropomyosin 3 | 0.0718261 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0645622 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0640736 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.0621225 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0553121 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0551259 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0529812 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.052075 |
| PTMA | prothymosin, alpha | 0.051831 |
| RPL4 | ribosomal protein L4 | 0.0482075 |
| UBC | ubiquitin C | 0.0481509 |
| RPL23 | ribosomal protein L23 | 0.0480205 |
| FGB | fibrinogen beta chain | 0.0474103 |
| CALR | calreticulin | 0.047144 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0454948 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0445423 |
| APP | amyloid beta (A4) precursor protein | 0.0441628 |
| RPL19 | ribosomal protein L19 | 0.0425651 |
| TXNRD1 | thioredoxin reductase 1 | 0.0422354 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0412347 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0409777 |
| PKM | pyruvate kinase, muscle | 0.0403935 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0392439 |
| FTL | ferritin, light polypeptide | 0.0388642 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0368944 |
| YBX1 | Y box binding protein 1 | 0.0367251 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0349926 |
| TFPI2 | tissue factor pathway inhibitor 2 | 0.0338548 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | 0.0335594 |
| TPI1 | triosephosphate isomerase 1 | 0.0333341 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0332129 |
| RHOA | ras homolog family member A | 0.0328726 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0325716 |
| RPS27A | ribosomal protein S27a | 0.0322323 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0321543 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0317177 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0316752 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0309218 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0306515 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0305694 |
| HDGF | hepatoma-derived growth factor | 0.0301628 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0298642 |
| RPS12 | ribosomal protein S12 | 0.0297907 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | 0.0296897 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0288689 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0280871 |
| PLEC | plectin | 0.0280692 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0278089 |
| AHNAK | AHNAK nucleoprotein | 0.0277649 |
| H1-4 | H1.4 linker histone, cluster member | 0.0277435 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0273909 |
| TPX2 | TPX2, microtubule-associated | 0.0273828 |
| MKI67 | marker of proliferation Ki-67 | 0.0273628 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.026898 |
| ENO1 | enolase 1, (alpha) | 0.0268257 |
| USP3 | ubiquitin specific peptidase 3 | 0.0267179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0266034 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0259665 |
| STMN1 | stathmin 1 | 0.0257327 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0256257 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0251956 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0251794 |
| CASC3 | cancer susceptibility candidate 3 | 0.0249756 |
| FLNA | filamin A, alpha | 0.0246902 |
| HYOU1 | hypoxia up-regulated 1 | 0.0242589 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0242075 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0240862 |
| KIF5B | kinesin family member 5B | 0.0240076 |
| TPD52 | tumor protein D52 | 0.023782 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0235676 |
| HDLBP | high density lipoprotein binding protein | 0.0234702 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0232295 |
| SET | SET nuclear proto-oncogene | 0.0228868 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0227734 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0227357 |
| RRM2 | ribonucleotide reductase M2 | 0.0226327 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0225897 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.022575 |
| SPAG5 | sperm associated antigen 5 | 0.022479 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0222796 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0222114 |
| RPL7 | ribosomal protein L7 | 0.0219079 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0217585 |
| ANLN | anillin, actin binding protein | 0.0209399 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.0208111 |
| RPS18 | ribosomal protein S18 | 0.0207951 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0204846 |
| VPS72 | vacuolar protein sorting 72 homolog (S. cerevisiae) | 0.020295 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0202149 |
| YWHAE | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon | 0.0202073 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0201436 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.019537 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0194216 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0193604 |
| SYNCRIP | synaptotagmin binding, cytoplasmic RNA interacting protein | 0.0192967 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.261344 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.205485 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.160893 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.137016 |
| DOCK4 | dedicator of cytokinesis 4 | -0.102543 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0787698 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0753259 |
| CMIP | c-Maf inducing protein | -0.0722639 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.0661611 |
| EGFR | epidermal growth factor receptor | -0.0610443 |
| MT2A | metallothionein 2A | -0.0606417 |
| BICC1 | BicC family RNA binding protein 1 | -0.0596078 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | -0.0594956 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0592396 |
| SMOC1 | SPARC related modular calcium binding 1 | -0.0569416 |
| GLIS3 | GLIS family zinc finger 3 | -0.0567653 |
| PARD3 | par-3 family cell polarity regulator | -0.0547894 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0545902 |
| TMSB10 | thymosin beta 10 | -0.0539073 |
| IGF2 | insulin-like growth factor 2 | -0.0531516 |
| PYGL | phosphorylase, glycogen, liver | -0.0531073 |
| SVIL | supervillin | -0.053071 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.052787 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0512635 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0508349 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0505104 |
| NEGR1 | neuronal growth regulator 1 | -0.0501653 |
| BASP1 | brain abundant, membrane attached signal protein 1 | -0.0494318 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0480887 |
| DST | dystonin | -0.048042 |
| KYNU | kynureninase | -0.0477064 |
| USP34 | ubiquitin specific peptidase 34 | -0.0459884 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.045768 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0453443 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0448089 |
| OSMR | oncostatin M receptor | -0.043904 |
| EFNA5 | ephrin-A5 | -0.0423127 |
| EHBP1 | EH domain binding protein 1 | -0.0421717 |
| MTHFD1L | methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like | -0.0400754 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0400465 |
| RAD51B | RAD51 paralog B | -0.039611 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0395432 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0391526 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0382207 |
| FMNL2 | formin-like 2 | -0.037648 |
| NAV3 | neuron navigator 3 | -0.0373603 |
| EGR1 | early growth response 1 | -0.0367225 |
| UTRN | utrophin | -0.0350511 |
| NRG1 | neuregulin 1 | -0.0342081 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0341123 |
| ATXN1 | ataxin 1 | -0.0337652 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0337165 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0335466 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0332388 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0330454 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0327348 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0320653 |
| BABAM2 | BRISC and BRCA1 A complex member 2 | -0.0320523 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0315992 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0314055 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0313509 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | -0.0312961 |
| EXOC6B | exocyst complex component 6B | -0.0312919 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0312865 |
| HDAC9 | histone deacetylase 9 | -0.0312158 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0301353 |
| FOXP1 | forkhead box P1 | -0.0301223 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | -0.0299286 |
| NEBL | nebulette | -0.0297415 |
| CSGALNACT1 | chondroitin sulfate N-acetylgalactosaminyltransferase 1 | -0.0297037 |
| ERBIN | erbb2 interacting protein | -0.0293659 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0293147 |
| GSK3B | glycogen synthase kinase 3 beta | -0.0292002 |
| TFPI | tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) | -0.0287904 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | -0.0275654 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.027469 |
| GRAMD1B | GRAM domain containing 1B | -0.0272896 |
| PCNX4 | pecanex 4 | -0.0272005 |
| WWOX | WW domain containing oxidoreductase | -0.0267422 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0266362 |
| MAP3K20 | mitogen-activated protein kinase kinase kinase 20 | -0.0265152 |
| NF1 | neurofibromin 1 | -0.0265125 |
| NHSL1 | NHS-like 1 | -0.0262803 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0261447 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0261223 |
| TBC1D5 | TBC1 domain family, member 5 | -0.0260536 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0260343 |
| CUX1 | cut-like homeobox 1 | -0.0260321 |
| ARHGEF28 | Rho guanine nucleotide exchange factor (GEF) 28 | -0.0258481 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0258371 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0254925 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0254845 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0253703 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0246884 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | -0.0245966 |
| AK1 | adenylate kinase 1 | -0.0245576 |
| IER3 | immediate early response 3 | -0.0242564 |
| SLC35F3 | solute carrier family 35, member F3 | -0.0241183 |
| RAB7A | RAB7A, member RAS oncogene family | -0.023907 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0237471 |
