| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H2122 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Decitabine_NCI-H2122 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.209797 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.187803 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.139461 |
| NDRG1 | N-myc downstream regulated 1 | 0.125063 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.112735 |
| FN1 | fibronectin 1 | 0.1047 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.101354 |
| CDH13 | cadherin 13 | 0.0943128 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0919889 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0850116 |
| FAM13A | family with sequence similarity 13, member A | 0.0839109 |
| PDE10A | phosphodiesterase 10A | 0.0821243 |
| VIM | vimentin | 0.0780641 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0734549 |
| KYNU | kynureninase | 0.0734442 |
| SPAG9 | sperm associated antigen 9 | 0.0703211 |
| FNDC3B | fibronectin type III domain containing 3B | 0.068719 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0653922 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0651736 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0611345 |
| TMSB4X | thymosin beta 4, X-linked | 0.0610024 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0604324 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0604305 |
| HELZ | helicase with zinc finger | 0.0598132 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0590843 |
| DST | dystonin | 0.0589306 |
| PDPK1 | 3-phosphoinositide dependent protein kinase 1 | 0.0577957 |
| RUNX1 | runt-related transcription factor 1 | 0.0573962 |
| LAMB3 | laminin, beta 3 | 0.0554871 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0554863 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | 0.0546702 |
| STC1 | stanniocalcin 1 | 0.0546596 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0533953 |
| MYOF | myoferlin | 0.0530846 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0524199 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | 0.0514836 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0504346 |
| ARRDC3 | arrestin domain containing 3 | 0.0489072 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0477199 |
| VAPA | VAMP (vesicle-associated membrane protein)-associated protein A, 33kDa | 0.0475141 |
| AFF4 | AF4/FMR2 family, member 4 | 0.0475087 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0472744 |
| CANX | calnexin | 0.0469449 |
| ARHGAP5 | Rho GTPase activating protein 5 | 0.0465097 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0464647 |
| LOX | lysyl oxidase | 0.04531 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0444257 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0434969 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0427133 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.042545 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0421289 |
| ANO6 | anoctamin 6 | 0.0416636 |
| MT2A | metallothionein 2A | 0.0412329 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0409341 |
| GLS2 | glutaminase 2 (liver, mitochondrial) | 0.0408873 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.040837 |
| DTNA | dystrobrevin, alpha | 0.0407198 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0406469 |
| INHBA | inhibin, beta A | 0.0401006 |
| HILPDA | hypoxia inducible lipid droplet-associated | 0.0398374 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0391744 |
| NGLY1 | N-glycanase 1 | 0.0391562 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0385873 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.038406 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0382959 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0382693 |
| USP3 | ubiquitin specific peptidase 3 | 0.0373366 |
| ZNF292 | zinc finger protein 292 | 0.0367333 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0365547 |
| RORA | RAR-related orphan receptor A | 0.036448 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | 0.0360608 |
| MYO10 | myosin X | 0.0359925 |
| PIAS1 | protein inhibitor of activated STAT, 1 | 0.0357031 |
| RPL3 | ribosomal protein L3 | 0.0356836 |
| SDC4 | syndecan 4 | 0.0353481 |
| COL8A1 | collagen, type VIII, alpha 1 | 0.035336 |
| SMAD3 | SMAD family member 3 | 0.0353126 |
| ERBIN | erbb2 interacting protein | 0.0351585 |
| CCNY | cyclin Y | 0.0346446 |
| KRT17 | keratin 17, type I | 0.0339567 |
| COG5 | component of oligomeric golgi complex 5 | 0.0338442 |
| XPO1 | exportin 1 | 0.0336045 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0334926 |
| CELF1 | CUGBP, Elav-like family member 1 | 0.0328776 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0326544 |
| SMAP1 | small ArfGAP 1 | 0.0324437 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0323568 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0318075 |
| JMJD1C | jumonji domain containing 1C | 0.0312661 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0312391 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0310099 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0308571 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0305258 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | 0.0300346 |
| HDLBP | high density lipoprotein binding protein | 0.0299204 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0295797 |
| PTPRJ | protein tyrosine phosphatase, receptor type, J | 0.0295749 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0295429 |
| RTN4 | reticulon 4 | 0.0295391 |
| RBM39 | RNA binding motif protein 39 | 0.029507 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | -0.130799 |
| FTL | ferritin, light polypeptide | -0.110309 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0789286 |
| RPL19 | ribosomal protein L19 | -0.0672916 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | -0.0642053 |
| IGF2 | insulin-like growth factor 2 | -0.0639534 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0639509 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0617056 |
| RPS8 | ribosomal protein S8 | -0.0593248 |
| RPS21 | ribosomal protein S21 | -0.0588366 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0570171 |
| MUC13 | mucin 13, cell surface associated | -0.0549566 |
| MMP1 | matrix metallopeptidase 1 | -0.0546152 |
| RPL7A | ribosomal protein L7a | -0.0545872 |
| MED13L | mediator complex subunit 13-like | -0.0535017 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.053232 |
| IER3 | immediate early response 3 | -0.0515497 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0512857 |
| TMSB10 | thymosin beta 10 | -0.0499385 |
| RPL31 | ribosomal protein L31 | -0.0498784 |
| NUP98 | nucleoporin 98kDa | -0.0493047 |
| BBX | bobby sox homolog (Drosophila) | -0.0486198 |
| PTMA | prothymosin, alpha | -0.0480799 |
| FAT1 | FAT atypical cadherin 1 | -0.048033 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0475947 |
| RPL36 | ribosomal protein L36 | -0.0474807 |
| FHIT | fragile histidine triad | -0.0471589 |
| KRT8 | keratin 8, type II | -0.047052 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0466703 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0460218 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0453945 |
| MSI2 | musashi RNA-binding protein 2 | -0.0452078 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0450724 |
| TSC22D1 | TSC22 domain family, member 1 | -0.0448529 |
| FOXP1 | forkhead box P1 | -0.0448312 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.043669 |
| NAV2 | neuron navigator 2 | -0.0432512 |
| RPL15 | ribosomal protein L15 | -0.043146 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0428267 |
| DNM2 | dynamin 2 | -0.0428052 |
| SERPINA1 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 | -0.0425002 |
| RPLP1 | ribosomal protein, large, P1 | -0.0422499 |
| ZEB1 | zinc finger E-box binding homeobox 1 | -0.0422184 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0420612 |
| RPS15 | ribosomal protein S15 | -0.0417494 |
| DICER1 | dicer 1, ribonuclease type III | -0.0415558 |
| ZFP36L1 | ZFP36 ring finger protein-like 1 | -0.0407642 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0403487 |
| STK24 | serine/threonine kinase 24 | -0.0401888 |
| NSRP1 | nuclear speckle splicing regulatory protein 1 | -0.0400975 |
| B2M | beta-2-microglobulin | -0.0400868 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0392992 |
| RPL12 | ribosomal protein L12 | -0.0390639 |
| SLTM | SAFB-like, transcription modulator | -0.0383771 |
| LMO7 | LIM domain 7 | -0.0383218 |
| CRADD | CASP2 and RIPK1 domain containing adaptor with death domain | -0.0380257 |
| HIPK2 | homeodomain interacting protein kinase 2 | -0.0380203 |
| HMGB1 | high mobility group box 1 | -0.0380021 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0379411 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0377192 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0376558 |
| ATP8B1 | ATPase, aminophospholipid transporter, class I, type 8B, member 1 | -0.037607 |
| PGK1 | phosphoglycerate kinase 1 | -0.0372557 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0371768 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.0370949 |
| RPS19 | ribosomal protein S19 | -0.0369459 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0362102 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0359424 |
| PKP4 | plakophilin 4 | -0.0358036 |
| CAPZA1 | capping protein (actin filament) muscle Z-line, alpha 1 | -0.0355113 |
| ENO1 | enolase 1, (alpha) | -0.0354836 |
| FAM107B | family with sequence similarity 107, member B | -0.0354141 |
| RPS13 | ribosomal protein S13 | -0.035352 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0353402 |
| RPS11 | ribosomal protein S11 | -0.0353142 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0351243 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | -0.034978 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0347833 |
| RBM15 | RNA binding motif protein 15 | -0.034621 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0345062 |
| METTL15 | methyltransferase like 15 | -0.0344158 |
| RPL35A | ribosomal protein L35a | -0.0343493 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | -0.0343148 |
| H3-3B | H3.3 histone B | -0.0342523 |
| NCOA3 | nuclear receptor coactivator 3 | -0.034125 |
| SRPK2 | SRSF protein kinase 2 | -0.0340352 |
| CUX1 | cut-like homeobox 1 | -0.0338287 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.0333607 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0328159 |
| RIOK3 | RIO kinase 3 | -0.0327247 |
| TIMP1 | TIMP metallopeptidase inhibitor 1 | -0.0325651 |
| RSRC1 | arginine/serine-rich coiled-coil 1 | -0.0323757 |
| MAP7 | microtubule-associated protein 7 | -0.0322294 |
| RBM25 | RNA binding motif protein 25 | -0.0320871 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0320196 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | -0.0319295 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0318998 |
| ETNK1 | ethanolamine kinase 1 | -0.0313842 |
| VGF | VGF nerve growth factor inducible | -0.031294 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0312794 |