| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H460 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_NCI-H460 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.154947 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.100434 |
| FN1 | fibronectin 1 | 0.0916687 |
| MCL1 | myeloid cell leukemia 1 | 0.087006 |
| RPL3 | ribosomal protein L3 | 0.0807601 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0796465 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.074548 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0678289 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0672163 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0651321 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.061559 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0589328 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0552881 |
| FLNB | filamin B, beta | 0.0551831 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0502133 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0475209 |
| OGA | O-GlcNAcase | 0.0463797 |
| SPAG9 | sperm associated antigen 9 | 0.0461105 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.045161 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0448723 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.0446877 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.044676 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0425257 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.0410252 |
| EZR | ezrin | 0.0405931 |
| TXNRD1 | thioredoxin reductase 1 | 0.0398522 |
| MSN | moesin | 0.0394731 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0392775 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0380266 |
| PGK1 | phosphoglycerate kinase 1 | 0.0378359 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0373793 |
| LDHA | lactate dehydrogenase A | 0.0369298 |
| UBC | ubiquitin C | 0.0357851 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0351885 |
| ARRDC3 | arrestin domain containing 3 | 0.0349657 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0344512 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0343971 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0343068 |
| NUP58 | nucleoporin 58 | 0.0342538 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0339226 |
| RTN4 | reticulon 4 | 0.0338224 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0330547 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0326309 |
| MKI67 | marker of proliferation Ki-67 | 0.0325118 |
| ATP13A3 | ATPase type 13A3 | 0.0316196 |
| CD109 | CD109 molecule | 0.0309296 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0300291 |
| PKM | pyruvate kinase, muscle | 0.0299881 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0298922 |
| WDR45B | WD repeat domain 45B | 0.0298434 |
| CTSL | cathepsin L | 0.0294461 |
| FLNA | filamin A, alpha | 0.028534 |
| PDGFA | platelet-derived growth factor alpha polypeptide | 0.0284893 |
| NEK7 | NIMA-related kinase 7 | 0.0279138 |
| TGFBR1 | transforming growth factor, beta receptor 1 | 0.0271332 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0268082 |
| MYOF | myoferlin | 0.0266474 |
| NCKAP1 | NCK-associated protein 1 | 0.0261863 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0260871 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0260721 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0260622 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0260483 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0259452 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0258635 |
| PCBP2 | poly(rC) binding protein 2 | 0.0256901 |
| RASSF8 | Ras association (RalGDS/AF-6) domain family (N-terminal) member 8 | 0.0252426 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0249957 |
| TPI1 | triosephosphate isomerase 1 | 0.024535 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0243902 |
| ECT2 | epithelial cell transforming 2 | 0.0242258 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0240696 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0238961 |
| NDRG1 | N-myc downstream regulated 1 | 0.0236506 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | 0.0236054 |
| CXCL5 | chemokine (C-X-C motif) ligand 5 | 0.0230954 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0230173 |
| FAM13A | family with sequence similarity 13, member A | 0.0229818 |
| TPM3 | tropomyosin 3 | 0.0229259 |
| HELZ | helicase with zinc finger | 0.022857 |
| KDM6A | lysine (K)-specific demethylase 6A | 0.0228059 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.022638 |
| RAI1 | retinoic acid induced 1 | 0.022635 |
| CDC73 | cell division cycle 73 | 0.0226099 |
| POTEF | POTE ankyrin domain family, member F | 0.0224907 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0224894 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0224432 |
| NONO | non-POU domain containing, octamer-binding | 0.0224417 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0224014 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.022296 |
| EPB41L3 | erythrocyte membrane protein band 4.1-like 3 | 0.0219771 |
| APP | amyloid beta (A4) precursor protein | 0.0217875 |
| H1-4 | H1.4 linker histone, cluster member | 0.0217367 |
| GRAMD1B | GRAM domain containing 1B | 0.0217016 |
| MYO10 | myosin X | 0.0215473 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0215464 |
| CNOT1 | CCR4-NOT transcription complex, subunit 1 | 0.0213982 |
| PDIA6 | protein disulfide isomerase family A, member 6 | 0.0213838 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | 0.021321 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0212717 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0212148 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.310767 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.235545 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.104616 |
| VIM | vimentin | -0.0946248 |
| CDH13 | cadherin 13 | -0.0913849 |
| PDE10A | phosphodiesterase 10A | -0.0877006 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.0863414 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0828593 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0698333 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0678323 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | -0.0673976 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0668568 |
| COL5A2 | collagen, type V, alpha 2 | -0.066568 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0629376 |
| PRKN | parkin RBR E3 ubiquitin protein ligase | -0.0624598 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0568309 |
| SMYD3 | SET and MYND domain containing 3 | -0.0532732 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.049693 |
| RPLP1 | ribosomal protein, large, P1 | -0.0486055 |
| P3H2 | prolyl 3-hydroxylase 2 | -0.0485828 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0471513 |
| RPS6 | ribosomal protein S6 | -0.0470317 |
| RPL35A | ribosomal protein L35a | -0.0438677 |
| LSAMP | limbic system-associated membrane protein | -0.0438249 |
| PTMA | prothymosin, alpha | -0.0437155 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0433787 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0423693 |
| RPS8 | ribosomal protein S8 | -0.041608 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0406476 |
| ADARB2 | adenosine deaminase, RNA-specific, B2 (non-functional) | -0.0367969 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.0358487 |
| PDLIM5 | PDZ and LIM domain 5 | -0.0342489 |
| CADM2 | cell adhesion molecule 2 | -0.0316284 |
| CTNND2 | catenin (cadherin-associated protein), delta 2 | -0.031085 |
| ANTXR1 | anthrax toxin receptor 1 | -0.030652 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0303322 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0298664 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0296993 |
| KIAA0825 | KIAA0825 | -0.0296742 |
| RPL31 | ribosomal protein L31 | -0.0289265 |
| NCKAP5 | NCK-associated protein 5 | -0.0286106 |
| TTC28 | tetratricopeptide repeat domain 28 | -0.0285776 |
| RAD51B | RAD51 paralog B | -0.0282915 |
| DST | dystonin | -0.0282631 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0281288 |
| PCBP3 | poly(rC) binding protein 3 | -0.0280919 |
| RPL34 | ribosomal protein L34 | -0.0279912 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0278569 |
| RPL9 | ribosomal protein L9 | -0.0278313 |
| DHRSX | dehydrogenase/reductase (SDR family) X-linked | -0.0277166 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.027044 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0265744 |
| SLC7A11 | solute carrier family 7 (anionic amino acid transporter light chain, xc- system), member 11 | -0.0264788 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0255028 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0253485 |
| RPLP0 | ribosomal protein, large, P0 | -0.0251631 |
| RPS24 | ribosomal protein S24 | -0.0250136 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0242556 |
| MAP7 | microtubule-associated protein 7 | -0.0238223 |
| SPOCK1 | sparc/osteonectin, cwcv and kazal-like domains proteoglycan (testican) 1 | -0.0236225 |
| CUX1 | cut-like homeobox 1 | -0.023174 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0226273 |
| PDE7B | phosphodiesterase 7B | -0.0224215 |
| PCDH15 | protocadherin-related 15 | -0.0221627 |
| AUTS2 | autism susceptibility candidate 2 | -0.021899 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0218306 |
| RPL26 | ribosomal protein L26 | -0.0215265 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0209261 |
| SOX4 | SRY (sex determining region Y)-box 4 | -0.0201537 |
| TENM3 | teneurin transmembrane protein 3 | -0.0200679 |
| XYLT1 | xylosyltransferase I | -0.0200351 |
| RPS14 | ribosomal protein S14 | -0.0199173 |
| BPTF | bromodomain PHD finger transcription factor | -0.0197216 |
| RPS27 | ribosomal protein S27 | -0.0191554 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0190787 |
| SH3KBP1 | SH3-domain kinase binding protein 1 | -0.0190071 |
| STEAP1B | STEAP family member 1B | -0.0189058 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0189046 |
| ADGRD1 | adhesion G protein-coupled receptor D1 | -0.018848 |
| INTS6 | integrator complex subunit 6 | -0.0187729 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0187501 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0184281 |
| S100A6 | S100 calcium binding protein A6 | -0.0184205 |
| VCL | vinculin | -0.0183527 |
| DOCK5 | dedicator of cytokinesis 5 | -0.0182555 |
| RTN1 | reticulon 1 | -0.0182332 |
| R3HDM2 | R3H domain containing 2 | -0.0181719 |
| RANBP17 | RAN binding protein 17 | -0.018147 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0177095 |
| EXOC4 | exocyst complex component 4 | -0.0176612 |
| AEBP2 | AE binding protein 2 | -0.0172813 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0172351 |
| SLC7A2 | solute carrier family 7 (cationic amino acid transporter, y+ system), member 2 | -0.0169788 |
| PRELID2 | PRELI domain containing 2 | -0.016881 |
| PDE1A | phosphodiesterase 1A, calmodulin-dependent | -0.0168414 |
| RAB31 | RAB31, member RAS oncogene family | -0.0167666 |
| TPM4 | tropomyosin 4 | -0.0165573 |
| RIGI | RNA sensor RIG-I | -0.0164698 |
| RPL12 | ribosomal protein L12 | -0.0164282 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.016217 |
