| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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189 genes differentially expressed following the Decitabine_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| RPS16 | ribosomal protein S16 | 0.165597 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0949284 |
| NF1 | neurofibromin 1 | 0.0940961 |
| APP | amyloid beta (A4) precursor protein | 0.0918718 |
| ANXA2 | annexin A2 | 0.091183 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0819788 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0729757 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0691561 |
| JMJD1C | jumonji domain containing 1C | 0.0628546 |
| CD44 | CD44 molecule (Indian blood group) | 0.0563758 |
| B2M | beta-2-microglobulin | 0.051861 |
| TM9SF3 | transmembrane 9 superfamily member 3 | 0.0506544 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0476081 |
| SETD5 | SET domain containing 5 | 0.0439412 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0400723 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0390062 |
| MYO1E | myosin IE | 0.0385474 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0379699 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0378464 |
| CDH13 | cadherin 13 | 0.0367857 |
| PLCB1 | phospholipase C, beta 1 (phosphoinositide-specific) | 0.0367463 |
| RPS24 | ribosomal protein S24 | 0.0364032 |
| RPL23 | ribosomal protein L23 | 0.0354515 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0347613 |
| PRKD3 | protein kinase D3 | 0.0339567 |
| SLC38A2 | solute carrier family 38, member 2 | 0.031695 |
| LDHA | lactate dehydrogenase A | 0.0314179 |
| RPS3 | ribosomal protein S3 | 0.0312982 |
| SET | SET nuclear proto-oncogene | 0.030524 |
| PTMA | prothymosin, alpha | 0.0303885 |
| IER3 | immediate early response 3 | 0.0301917 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0297438 |
| TPI1 | triosephosphate isomerase 1 | 0.029572 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0292582 |
| RTN4 | reticulon 4 | 0.0286026 |
| RPS6 | ribosomal protein S6 | 0.0276305 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0275453 |
| KIZ | kizuna centrosomal protein | 0.0270352 |
| VIM | vimentin | 0.0267827 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.025878 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0256112 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0253996 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0251983 |
| RPS12 | ribosomal protein S12 | 0.0227575 |
| MAML2 | mastermind-like 2 (Drosophila) | 0.0214181 |
| FBL | fibrillarin | 0.0204713 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0195026 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0190416 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0170279 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0169374 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0154256 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0147412 |
| KDM5B | lysine (K)-specific demethylase 5B | 0.0139742 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0138585 |
| CERS6 | ceramide synthase 6 | 0.0137262 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | 0.0132805 |
| SLTM | SAFB-like, transcription modulator | 0.0131512 |
| PARD3 | par-3 family cell polarity regulator | 0.0130638 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | 0.0129003 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0128247 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0116481 |
| SRPK2 | SRSF protein kinase 2 | 0.0116236 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | 0.011466 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0111402 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0111311 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0105005 |
| XRN2 | 5'-3' exoribonuclease 2 | 0.00990889 |
| SLC2A13 | solute carrier family 2 (facilitated glucose transporter), member 13 | 0.00987885 |
| ATP1A4 | ATPase, Na+/K+ transporting, alpha 4 polypeptide | 0.00939873 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.00854186 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.00800438 |
| ITGA6 | integrin, alpha 6 | 0.0076047 |
| PIBF1 | progesterone immunomodulatory binding factor 1 | 0.00751268 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.00663444 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.00635307 |
| RPL37 | ribosomal protein L37 | 0.00628765 |
| TCF7L2 | transcription factor 7-like 2 (T-cell specific, HMG-box) | 0.00587591 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.00580744 |
| RORA | RAR-related orphan receptor A | 0.00570466 |
| GOLGA4 | golgin A4 | 0.00565597 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.00503034 |
| FNDC3B | fibronectin type III domain containing 3B | 0.00449935 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.00349434 |
| AOPEP | aminopeptidase O (putative) | 0.00330845 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0032786 |
| UBE2D3 | ubiquitin-conjugating enzyme E2D 3 | 0.00218533 |
| MARCHF7 | membrane associated ring-CH-type finger 7 | 0.00159201 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | 0.0015822 |
| TOP1 | topoisomerase (DNA) I | 3.36176E-4 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.10916 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0916366 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0889787 |
| FAM13A | family with sequence similarity 13, member A | -0.0860316 |
| ELL2 | elongation factor, RNA polymerase II, 2 | -0.0814289 |
| NDRG1 | N-myc downstream regulated 1 | -0.0788927 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0674808 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0516301 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0515165 |
| RPLP2 | ribosomal protein, large, P2 | -0.0509431 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0505047 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0503687 |
| CANX | calnexin | -0.0503507 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.04843 |
| ENO1 | enolase 1, (alpha) | -0.0466081 |
| RPL19 | ribosomal protein L19 | -0.0464985 |
| MT2A | metallothionein 2A | -0.0453765 |
| PKM | pyruvate kinase, muscle | -0.0446179 |
| EFNA5 | ephrin-A5 | -0.0424881 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0419927 |
| RPL28 | ribosomal protein L28 | -0.0414583 |
| ASPH | aspartate beta-hydroxylase | -0.0414185 |
| WASF2 | WAS protein family, member 2 | -0.0392684 |
| SMURF1 | SMAD specific E3 ubiquitin protein ligase 1 | -0.0387575 |
| RPL35A | ribosomal protein L35a | -0.0370881 |
| FTL | ferritin, light polypeptide | -0.0332108 |
| NAV2 | neuron navigator 2 | -0.0330323 |
| DST | dystonin | -0.032582 |
| FNDC3A | fibronectin type III domain containing 3A | -0.0324633 |
| RPS8 | ribosomal protein S8 | -0.0309346 |
| RBM25 | RNA binding motif protein 25 | -0.0293344 |
| MORF4L2 | mortality factor 4 like 2 | -0.0273588 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0266569 |
| CCNI | cyclin I | -0.0259881 |
| RPLP0 | ribosomal protein, large, P0 | -0.0259513 |
| RPLP1 | ribosomal protein, large, P1 | -0.0253072 |
| RPS25 | ribosomal protein S25 | -0.0243589 |
| CDC42BPA | CDC42 binding protein kinase alpha (DMPK-like) | -0.0232229 |
| SPATA13 | spermatogenesis associated 13 | -0.0223786 |
| RPS19 | ribosomal protein S19 | -0.0223726 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0222369 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0220397 |
| ARPC1B | actin related protein 2/3 complex, subunit 1B, 41kDa | -0.0202601 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0199456 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | -0.0198212 |
| MED13L | mediator complex subunit 13-like | -0.0194517 |
| LMO7 | LIM domain 7 | -0.0193596 |
| KDM2A | lysine (K)-specific demethylase 2A | -0.0186182 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | -0.0182573 |
| TAF15 | TAF15 RNA polymerase II, TATA box binding protein (TBP)-associated factor, 68kDa | -0.0181984 |
| RPS14 | ribosomal protein S14 | -0.0175201 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0166378 |
| RIGI | RNA sensor RIG-I | -0.016104 |
| CARD16 | caspase recruitment domain family, member 16 | -0.0151341 |
| RPL12 | ribosomal protein L12 | -0.0147619 |
| TSC22D2 | TSC22 domain family, member 2 | -0.014201 |
| LAMB3 | laminin, beta 3 | -0.0126374 |
| SNX9 | sorting nexin 9 | -0.0124829 |
| OGA | O-GlcNAcase | -0.0117665 |
| TXNRD1 | thioredoxin reductase 1 | -0.0114975 |
| MYOF | myoferlin | -0.011321 |
| KANSL1 | KAT8 regulatory NSL complex subunit 1 | -0.0113156 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0111358 |
| UBE2H | ubiquitin-conjugating enzyme E2H | -0.0108603 |
| TMSB10 | thymosin beta 10 | -0.0108065 |
| TCF12 | transcription factor 12 | -0.0103762 |
| NUFIP2 | nuclear fragile X mental retardation protein interacting protein 2 | -0.0101743 |
| NKD1 | naked cuticle homolog 1 (Drosophila) | -0.0101397 |
| RPL37A | ribosomal protein L37a | -0.0101322 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.00947477 |
| FN1 | fibronectin 1 | -0.0087303 |
| ARHGEF12 | Rho guanine nucleotide exchange factor (GEF) 12 | -0.00855002 |
| RPL26 | ribosomal protein L26 | -0.00757706 |
| LOC112694756 | uncharaterized LOC112694756 | -0.00712918 |
| HNRNPD | heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa) | -0.00698589 |
| SLC38A1 | solute carrier family 38, member 1 | -0.00626334 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.00567117 |
| RYBP | RING1 and YY1 binding protein | -0.00565092 |
| SMAD3 | SMAD family member 3 | -0.00539502 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00526697 |
| NBEAL1 | neurobeachin-like 1 | -0.00499687 |
| GRB10 | growth factor receptor-bound protein 10 | -0.00494878 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.00437274 |
| ELOVL5 | ELOVL fatty acid elongase 5 | -0.00408854 |
| SAMD4A | sterile alpha motif domain containing 4A | -0.00402023 |
| BBX | bobby sox homolog (Drosophila) | -0.00393803 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.00378983 |
| EZR | ezrin | -0.00362851 |
| STAG2 | stromal antigen 2 | -0.00357564 |
| KRT18 | keratin 18, type I | -0.00354685 |
| ARHGAP32 | Rho GTPase activating protein 32 | -0.00351747 |
| KPNB1 | karyopherin (importin) beta 1 | -0.00337838 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0029296 |
| PGK1 | phosphoglycerate kinase 1 | -0.00224219 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.00224137 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.00208753 |
| EGFR | epidermal growth factor receptor | -0.00197334 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.00176744 |
| PLEKHA5 | pleckstrin homology domain containing, family A member 5 | -0.00155237 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | -0.00154514 |
