| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.139882 |
| MKI67 | marker of proliferation Ki-67 | 0.117298 |
| COL3A1 | collagen, type III, alpha 1 | 0.104283 |
| H1-4 | H1.4 linker histone, cluster member | 0.0974154 |
| COL5A2 | collagen, type V, alpha 2 | 0.0963414 |
| TMSB4X | thymosin beta 4, X-linked | 0.0926414 |
| COL11A1 | collagen, type XI, alpha 1 | 0.0729295 |
| VIM | vimentin | 0.0700522 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0681684 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0651711 |
| LOC112694756 | uncharaterized LOC112694756 | 0.0641987 |
| NACA | nascent polypeptide-associated complex alpha subunit | 0.0606894 |
| AHNAK | AHNAK nucleoprotein | 0.0589853 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0562472 |
| RPL3 | ribosomal protein L3 | 0.0561225 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.049627 |
| RPL23 | ribosomal protein L23 | 0.0490673 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | 0.0473066 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0456105 |
| ACTG1 | actin gamma 1 | 0.0444681 |
| RPL4 | ribosomal protein L4 | 0.0433206 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0418319 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0411474 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0409822 |
| BAZ1A | bromodomain adjacent to zinc finger domain, 1A | 0.0406885 |
| COL1A2 | collagen, type I, alpha 2 | 0.0404501 |
| ENO1 | enolase 1, (alpha) | 0.0403286 |
| CENPF | centromere protein F, 350/400kDa | 0.0402948 |
| TPM3 | tropomyosin 3 | 0.0393325 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0392157 |
| MDK | midkine (neurite growth-promoting factor 2) | 0.0388797 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | 0.0388783 |
| STMN1 | stathmin 1 | 0.0388671 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0385165 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0377656 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0370559 |
| CADM2 | cell adhesion molecule 2 | 0.0369671 |
| CKAP2 | cytoskeleton associated protein 2 | 0.0366442 |
| H1-2 | H1.2 linker histone, cluster member | 0.0364909 |
| LRMDA | leucine rich melanocyte differentiation associated | 0.0364765 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0355096 |
| CALR | calreticulin | 0.0352245 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0351915 |
| ADGRL2 | adhesion G protein-coupled receptor L2 | 0.0351518 |
| H1-5 | H1.5 linker histone, cluster member | 0.0349074 |
| DST | dystonin | 0.034883 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0346144 |
| RPL11 | ribosomal protein L11 | 0.0343875 |
| CAVIN1 | caveolae associated protein 1 | 0.0342926 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0339857 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0339068 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0338393 |
| ASPM | asp (abnormal spindle) homolog, microcephaly associated (Drosophila) | 0.0327029 |
| SERPINH1 | serpin peptidase inhibitor, clade H (heat shock protein 47), member 1, (collagen binding protein 1) | 0.0326753 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0325599 |
| SET | SET nuclear proto-oncogene | 0.032022 |
| PPIA | peptidylprolyl isomerase A (cyclophilin A) | 0.0318795 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.0317278 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | 0.0316969 |
| SKIL | SKI-like proto-oncogene | 0.0314332 |
| RPS8 | ribosomal protein S8 | 0.0305171 |
| STIP1 | stress-induced phosphoprotein 1 | 0.0301532 |
| HNRNPH1 | heterogeneous nuclear ribonucleoprotein H1 (H) | 0.0296109 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0294688 |
| RIGI | RNA sensor RIG-I | 0.0294563 |
| EIF4G2 | eukaryotic translation initiation factor 4 gamma, 2 | 0.0294208 |
| ANXA1 | annexin A1 | 0.029368 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0292514 |
| BZW1 | basic leucine zipper and W2 domains 1 | 0.0291507 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0290958 |
| FLNA | filamin A, alpha | 0.0290749 |
| SSRP1 | structure specific recognition protein 1 | 0.0290103 |
| SRP72 | signal recognition particle 72kDa | 0.0289918 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0286665 |
| NTM | neurotrimin | 0.0286371 |
| ABCF1 | ATP-binding cassette, sub-family F (GCN20), member 1 | 0.0284696 |
| LMNA | lamin A/C | 0.0283289 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0280335 |
| SSR1 | signal sequence receptor, alpha | 0.0279428 |
| RPLP1 | ribosomal protein, large, P1 | 0.0279419 |
| ATP5F1B | ATP synthase F1 subunit beta | 0.0277885 |
| SSB | Sjogren syndrome antigen B (autoantigen La) | 0.0277045 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0274855 |
| H1-0 | H1.0 linker histone | 0.0273884 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0272081 |
| ACIN1 | apoptotic chromatin condensation inducer 1 | 0.0270533 |
| B2M | beta-2-microglobulin | 0.0268276 |
| FOXP2 | forkhead box P2 | 0.0268258 |
| PCDH9 | protocadherin 9 | 0.0266771 |
| RPS12 | ribosomal protein S12 | 0.0262622 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0262263 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0262055 |
| SQSTM1 | sequestosome 1 | 0.0261563 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0260978 |
| RPS6 | ribosomal protein S6 | 0.0260883 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0259367 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0258651 |
| CHD4 | chromodomain helicase DNA binding protein 4 | 0.0256359 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0253727 |
| SPIRE1 | spire-type actin nucleation factor 1 | 0.0253024 |
| Symbol | Name | Standardized Value |
|---|---|---|
| TSC22D2 | TSC22 domain family, member 2 | -0.183169 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0836765 |
| ZNF292 | zinc finger protein 292 | -0.0818166 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0816445 |
| PPP1R12A | protein phosphatase 1, regulatory subunit 12A | -0.0799949 |
| PHIP | pleckstrin homology domain interacting protein | -0.0776763 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0750189 |
| MRPS30 | mitochondrial ribosomal protein S30 | -0.0720794 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0694553 |
| KMT2E | lysine (K)-specific methyltransferase 2E | -0.0634538 |
| FBXO11 | F-box protein 11 | -0.0612894 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | -0.061031 |
| ADAM9 | ADAM metallopeptidase domain 9 | -0.0608368 |
| BACH2 | BTB and CNC homology 1, basic leucine zipper transcription factor 2 | -0.058463 |
| PFN1 | profilin 1 | -0.0581046 |
| RBM39 | RNA binding motif protein 39 | -0.0562893 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0552041 |
| CDC73 | cell division cycle 73 | -0.0536832 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0528328 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | -0.0520817 |
| MTF2 | metal response element binding transcription factor 2 | -0.0498728 |
| PPP4R1 | protein phosphatase 4, regulatory subunit 1 | -0.0479688 |
| TBC1D12 | TBC1 domain family, member 12 | -0.0476642 |
| PRR16 | proline rich 16 | -0.0475508 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0468787 |
| RLF | rearranged L-myc fusion | -0.0451624 |
| URI1 | URI1, prefoldin-like chaperone | -0.0444373 |
| SETD5 | SET domain containing 5 | -0.0436598 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0436419 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | -0.0430751 |
| RAPGEF2 | Rap guanine nucleotide exchange factor (GEF) 2 | -0.0419566 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0417787 |
| HDAC9 | histone deacetylase 9 | -0.0417315 |
| WAC | WW domain containing adaptor with coiled-coil | -0.0414706 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | -0.041122 |
| WDR43 | WD repeat domain 43 | -0.040907 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0402024 |
| ITGAV | integrin, alpha V | -0.0394511 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0389489 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.0380147 |
| ADGRL3 | adhesion G protein-coupled receptor L3 | -0.0379314 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.0379112 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0374025 |
| MED13L | mediator complex subunit 13-like | -0.0365073 |
| RHEB | Ras homolog enriched in brain | -0.0359873 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | -0.0355124 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0354262 |
| CXADR | coxsackie virus and adenovirus receptor | -0.0353592 |
| QKI | QKI, KH domain containing, RNA binding | -0.0353588 |
| USP3 | ubiquitin specific peptidase 3 | -0.03531 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.035193 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0348051 |
| GPC3 | glypican 3 | -0.0346272 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0344253 |
| HELZ | helicase with zinc finger | -0.0339109 |
| SRP54 | signal recognition particle 54kDa | -0.0338605 |
| ENAH | enabled homolog (Drosophila) | -0.0338317 |
| NOP58 | NOP58 ribonucleoprotein | -0.0334262 |
| PDS5A | PDS5 cohesin associated factor A | -0.0334057 |
| FAM168A | family with sequence similarity 168, member A | -0.0332691 |
| DENND4C | DENN/MADD domain containing 4C | -0.0332036 |
| DNAJC1 | DnaJ (Hsp40) homolog, subfamily C, member 1 | -0.0324627 |
| SCAF11 | SR-related CTD-associated factor 11 | -0.0320026 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0319647 |
| RBM27 | RNA binding motif protein 27 | -0.0317723 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | -0.0317215 |
| CHD1 | chromodomain helicase DNA binding protein 1 | -0.0316142 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0316066 |
| PLPP1 | phospholipid phosphatase 1 | -0.0312887 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0310622 |
| VEZT | vezatin, adherens junctions transmembrane protein | -0.0308613 |
| HYCC2 | hyccin PI4KA lipid kinase complex subunit 2 | -0.030672 |
| ERBB4 | erb-b2 receptor tyrosine kinase 4 | -0.0305576 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.030465 |
| ARHGAP12 | Rho GTPase activating protein 12 | -0.0302456 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | -0.0301363 |
| CCNL1 | cyclin L1 | -0.0301137 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | -0.029602 |
| NPR2 | natriuretic peptide receptor 2 | -0.0294015 |
| TLK2 | tousled-like kinase 2 | -0.0293053 |
| SMAP1 | small ArfGAP 1 | -0.0292792 |
| EVI5 | ecotropic viral integration site 5 | -0.0291861 |
| NHSL1 | NHS-like 1 | -0.0289319 |
| CBL | Cbl proto-oncogene, E3 ubiquitin protein ligase | -0.0289169 |
| RBM33 | RNA binding motif protein 33 | -0.0286611 |
| CAPZA2 | capping protein (actin filament) muscle Z-line, alpha 2 | -0.0285937 |
| TRAM1 | translocation associated membrane protein 1 | -0.0283173 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0281347 |
| RNF13 | ring finger protein 13 | -0.0278784 |
| SRPK2 | SRSF protein kinase 2 | -0.0276765 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | -0.0276343 |
| TMOD3 | tropomodulin 3 (ubiquitous) | -0.0273102 |
| GRB2 | growth factor receptor-bound protein 2 | -0.0272696 |
| FAM171B | family with sequence similarity 171, member B | -0.0272088 |
| HS3ST5 | heparan sulfate (glucosamine) 3-O-sulfotransferase 5 | -0.0269317 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | -0.026925 |
| PRTG | protogenin | -0.0267091 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | -0.0266717 |
| ATXN2 | ataxin 2 | -0.0265733 |
| MAP4 | microtubule-associated protein 4 | -0.0264431 |
