| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Decitabine perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Decitabine_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FN1 | fibronectin 1 | 0.2209 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.209242 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | 0.107139 |
| VIM | vimentin | 0.102369 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0914561 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0866192 |
| LOC112694756 | uncharaterized LOC112694756 | 0.084881 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0805558 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0712229 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0705238 |
| MKI67 | marker of proliferation Ki-67 | 0.0645256 |
| CD44 | CD44 molecule (Indian blood group) | 0.0611827 |
| FRMD4A | FERM domain containing 4A | 0.0595824 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0591781 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0570592 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0570313 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0556119 |
| MSN | moesin | 0.0550605 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0545167 |
| FLNA | filamin A, alpha | 0.0541221 |
| RTN4 | reticulon 4 | 0.0530743 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0501368 |
| PGK1 | phosphoglycerate kinase 1 | 0.0494964 |
| COL6A3 | collagen, type VI, alpha 3 | 0.0492832 |
| CENPF | centromere protein F, 350/400kDa | 0.0489881 |
| RPL3 | ribosomal protein L3 | 0.0474982 |
| FLNB | filamin B, beta | 0.0471652 |
| NAV2 | neuron navigator 2 | 0.047018 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0456267 |
| AHNAK | AHNAK nucleoprotein | 0.0444277 |
| MYOF | myoferlin | 0.043819 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0429221 |
| COL1A2 | collagen, type I, alpha 2 | 0.0413426 |
| LDHA | lactate dehydrogenase A | 0.0410908 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0402231 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0401668 |
| SFTPA2 | surfactant protein A2 | 0.0396443 |
| TXNIP | thioredoxin interacting protein | 0.0389069 |
| VCAN | versican | 0.0381413 |
| ICAM1 | intercellular adhesion molecule 1 | 0.037067 |
| ARRDC3 | arrestin domain containing 3 | 0.0353455 |
| TMSB4X | thymosin beta 4, X-linked | 0.035278 |
| ANLN | anillin, actin binding protein | 0.0345634 |
| COL1A1 | collagen, type I, alpha 1 | 0.0342858 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0326138 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0325758 |
| B2M | beta-2-microglobulin | 0.032179 |
| APP | amyloid beta (A4) precursor protein | 0.0321172 |
| ENO1 | enolase 1, (alpha) | 0.0320963 |
| OGA | O-GlcNAcase | 0.0318957 |
| CADM1 | cell adhesion molecule 1 | 0.031713 |
| UBC | ubiquitin C | 0.0315775 |
| JUN | jun proto-oncogene | 0.031392 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0312846 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0310713 |
| ADM | adrenomedullin | 0.0305097 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0297793 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.029777 |
| NONO | non-POU domain containing, octamer-binding | 0.0296897 |
| ACTN1 | actinin, alpha 1 | 0.0296485 |
| SEPTIN9 | septin 9 | 0.0290016 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0289535 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0288359 |
| SMAD3 | SMAD family member 3 | 0.0288046 |
| TPX2 | TPX2, microtubule-associated | 0.028744 |
| TPM4 | tropomyosin 4 | 0.0286777 |
| UBE2E1 | ubiquitin-conjugating enzyme E2E 1 | 0.0282281 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0281728 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0281274 |
| ANXA2 | annexin A2 | 0.0281254 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | 0.0279843 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0276746 |
| KLF6 | Kruppel-like factor 6 | 0.0274563 |
| CALD1 | caldesmon 1 | 0.0274346 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0270486 |
| OPTN | optineurin | 0.0269368 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0264947 |
| SBF2 | SET binding factor 2 | 0.0261497 |
| CTSD | cathepsin D | 0.0260733 |
| EGR1 | early growth response 1 | 0.0258667 |
| KPNB1 | karyopherin (importin) beta 1 | 0.0256594 |
| ATP13A3 | ATPase type 13A3 | 0.0255255 |
| AFDN | afadin, adherens junction formation factor | 0.0252991 |
| H1-4 | H1.4 linker histone, cluster member | 0.0252258 |
| SDC4 | syndecan 4 | 0.0250479 |
| CTSB | cathepsin B | 0.0250289 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0247521 |
| CD59 | CD59 molecule, complement regulatory protein | 0.0246555 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | 0.0243328 |
| MCL1 | myeloid cell leukemia 1 | 0.0241988 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.024166 |
| TXNRD1 | thioredoxin reductase 1 | 0.0240355 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0238489 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0237131 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0236896 |
| CSDE1 | cold shock domain containing E1, RNA-binding | 0.0235115 |
| TAPBP | TAP binding protein (tapasin) | 0.0234796 |
| KIF4A | kinesin family member 4A | 0.0234634 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0234392 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.022983 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0982705 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0904029 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0778047 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.0751129 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.070536 |
| INTS6 | integrator complex subunit 6 | -0.0660267 |
| RPS12 | ribosomal protein S12 | -0.061238 |
| HMGA2 | high mobility group AT-hook 2 | -0.0611915 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0574613 |
| RPS3 | ribosomal protein S3 | -0.0552827 |
| RPL37A | ribosomal protein L37a | -0.0535833 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0534226 |
| MT2A | metallothionein 2A | -0.0512205 |
| CDH13 | cadherin 13 | -0.0502858 |
| KYNU | kynureninase | -0.0498229 |
| AFF3 | AF4/FMR2 family, member 3 | -0.0440818 |
| GLIS3 | GLIS family zinc finger 3 | -0.043779 |
| RPLP2 | ribosomal protein, large, P2 | -0.0434102 |
| FRMPD4 | FERM and PDZ domain containing 4 | -0.039864 |
| EFNA5 | ephrin-A5 | -0.0371746 |
| PDE10A | phosphodiesterase 10A | -0.0365565 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0365146 |
| RPS8 | ribosomal protein S8 | -0.0354309 |
| RPS23 | ribosomal protein S23 | -0.0350936 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0350456 |
| HERC4 | HECT and RLD domain containing E3 ubiquitin protein ligase 4 | -0.0329354 |
| PAPPA | pregnancy-associated plasma protein A, pappalysin 1 | -0.0314422 |
| HDAC9 | histone deacetylase 9 | -0.0314179 |
| RPL7A | ribosomal protein L7a | -0.0314076 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0311023 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.031096 |
| FNIP1 | folliculin interacting protein 1 | -0.0303125 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0302916 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0298093 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0297662 |
| CANX | calnexin | -0.029751 |
| RPL31 | ribosomal protein L31 | -0.0296714 |
| RPL26 | ribosomal protein L26 | -0.0293467 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0286388 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0271548 |
| SQSTM1 | sequestosome 1 | -0.0268142 |
| BICC1 | BicC family RNA binding protein 1 | -0.0262405 |
| RPS29 | ribosomal protein S29 | -0.0261071 |
| RPL5 | ribosomal protein L5 | -0.0254957 |
| SMYD3 | SET and MYND domain containing 3 | -0.0254391 |
| RPS10 | ribosomal protein S10 | -0.0242585 |
| CDK13 | cyclin-dependent kinase 13 | -0.0241377 |
| RPS19 | ribosomal protein S19 | -0.0240427 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.023845 |
| NABP1 | nucleic acid binding protein 1 | -0.023824 |
| SUPT3H | suppressor of Ty 3 homolog (S. cerevisiae) | -0.0237317 |
| PCBP3 | poly(rC) binding protein 3 | -0.0236854 |
| RAI14 | retinoic acid induced 14 | -0.023422 |
| RBFOX1 | RNA binding protein, fox-1 homolog (C. elegans) 1 | -0.0233538 |
| ZHX2 | zinc fingers and homeoboxes 2 | -0.02314 |
| TMSB10 | thymosin beta 10 | -0.022482 |
| PHF3 | PHD finger protein 3 | -0.0221315 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0216948 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.021647 |
| KDM4C | lysine (K)-specific demethylase 4C | -0.0212584 |
| RTN3 | reticulon 3 | -0.0211525 |
| PRELID2 | PRELI domain containing 2 | -0.020799 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0207847 |
| RPS13 | ribosomal protein S13 | -0.0206668 |
| RPS24 | ribosomal protein S24 | -0.0204022 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0203607 |
| TMEM132D | transmembrane protein 132D | -0.0202638 |
| GOLGB1 | golgin B1 | -0.020184 |
| RND3 | Rho family GTPase 3 | -0.0200531 |
| USP53 | ubiquitin specific peptidase 53 | -0.0198599 |
| VAC14 | Vac14 homolog (S. cerevisiae) | -0.019807 |
| RPS27A | ribosomal protein S27a | -0.0195909 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0195703 |
| N4BP2L2 | NEDD4 binding protein 2-like 2 | -0.0195527 |
| PTH2R | parathyroid hormone 2 receptor | -0.0194424 |
| EGFR | epidermal growth factor receptor | -0.0193774 |
| SIPA1L1 | signal-induced proliferation-associated 1 like 1 | -0.0192612 |
| RPS16 | ribosomal protein S16 | -0.0192299 |
| RPS17 | ribosomal protein S17 | -0.0189325 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0188314 |
| SDCBP | syndecan binding protein (syntenin) | -0.018622 |
| DIAPH2 | diaphanous-related formin 2 | -0.0185292 |
| NR6A1 | nuclear receptor subfamily 6, group A, member 1 | -0.0185245 |
| PLSCR1 | phospholipid scramblase 1 | -0.0183287 |
| RPL23 | ribosomal protein L23 | -0.0181447 |
| RPL36A | ribosomal protein L36a | -0.0180648 |
| ASCC3 | activating signal cointegrator 1 complex subunit 3 | -0.0179753 |
| ASPH | aspartate beta-hydroxylase | -0.0177847 |
| GDF15 | growth differentiation factor 15 | -0.0175299 |
| MMP12 | matrix metallopeptidase 12 | -0.017395 |
| PALLD | palladin, cytoskeletal associated protein | -0.0170969 |
| KANSL1L | KAT8 regulatory NSL complex subunit 1-like | -0.0167087 |
| SAMD3 | sterile alpha motif domain containing 3 | -0.0166658 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0165868 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.016582 |
| RPS25 | ribosomal protein S25 | -0.0165416 |
| TLE4 | transducin-like enhancer of split 4 | -0.0163999 |
| DDIT3 | DNA-damage-inducible transcript 3 | -0.0161836 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | -0.0161718 |
| TBC1D22A | TBC1 domain family, member 22A | -0.0161522 |
