Decitabine_SW 1271 Gene Set

Dataset Tahoe Therapeutics Tahoe 100M Perturbation Atlas
Category transcriptomics
Type cell type
Description Decitabine perturbation in SW 1271 cell line (Tahoe Therapeutics)
Similar Terms
Downloads & Tools

Genes

200 genes differentially expressed following the Decitabine_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.

increased expression

Symbol Name Standardized Value
LOC112694756 uncharaterized LOC112694756 0.108375
MYH9 myosin, heavy chain 9, non-muscle 0.0831488
EEF2 eukaryotic translation elongation factor 2 0.0796034
MSN moesin 0.0777321
CEP250 centrosomal protein 250kDa 0.0648175
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 0.0607074
HSP90B1 heat shock protein 90kDa beta (Grp94), member 1 0.0599713
AHNAK AHNAK nucleoprotein 0.0595838
ERO1A endoplasmic reticulum oxidoreductase 1 alpha 0.0586542
HSPA8 heat shock 70kDa protein 8 0.0556266
SPAG9 sperm associated antigen 9 0.0520672
RPL3 ribosomal protein L3 0.050138
PJA2 praja ring finger 2, E3 ubiquitin protein ligase 0.0468518
HILPDA hypoxia inducible lipid droplet-associated 0.0463031
PDE4D phosphodiesterase 4D, cAMP-specific 0.045955
TUBB tubulin, beta class I 0.045519
FLNB filamin B, beta 0.0444664
ENO1 enolase 1, (alpha) 0.0444025
FLNA filamin A, alpha 0.0438119
CALU calumenin 0.0418065
NSD2 nuclear receptor binding SET domain protein 2 0.0414491
SPTBN1 spectrin, beta, non-erythrocytic 1 0.040233
BBX bobby sox homolog (Drosophila) 0.0392748
SLC2A3 solute carrier family 2 (facilitated glucose transporter), member 3 0.0386026
MACF1 microtubule-actin crosslinking factor 1 0.0377613
ARRDC3 arrestin domain containing 3 0.0358007
ANLN anillin, actin binding protein 0.03557
MAP4K4 mitogen-activated protein kinase kinase kinase kinase 4 0.0354653
HSP90AA1 heat shock protein 90kDa alpha (cytosolic), class A member 1 0.0352515
EIF4A1 eukaryotic translation initiation factor 4A1 0.0351493
CKAP5 cytoskeleton associated protein 5 0.0348102
TPI1 triosephosphate isomerase 1 0.0342867
PLEC plectin 0.0338915
YWHAQ tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta 0.0336085
H1-4 H1.4 linker histone, cluster member 0.0328166
HDLBP high density lipoprotein binding protein 0.0319112
NUMA1 nuclear mitotic apparatus protein 1 0.030979
SEC24A SEC24 family member A 0.0308231
ITGA2 integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) 0.0306886
HNRNPU heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) 0.0306705
EIF4H eukaryotic translation initiation factor 4H 0.0302953
HIPK3 homeodomain interacting protein kinase 3 0.0300752
PICALM phosphatidylinositol binding clathrin assembly protein 0.0300631
TRA2A transformer 2 alpha homolog (Drosophila) 0.0298013
TNIP1 TNFAIP3 interacting protein 1 0.0287463
CTNNA1 catenin (cadherin-associated protein), alpha 1, 102kDa 0.0286122
PALM2AKAP2 PALM2 and AKAP2 fusion 0.0285035
SEPTIN9 septin 9 0.0278735
NONO non-POU domain containing, octamer-binding 0.0277136
MIS18BP1 MIS18 binding protein 1 0.0275854
ANKRD11 ankyrin repeat domain 11 0.0274456
NEDD4L neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase 0.0271267
PPP1R15A protein phosphatase 1, regulatory subunit 15A 0.0270944
ECPAS Ecm29 proteasome adaptor and scaffold 0.0269738
GPRC5A G protein-coupled receptor, class C, group 5, member A 0.0265974
CLIC4 chloride intracellular channel 4 0.0262331
NKTR natural killer cell triggering receptor 0.026135
RPL4 ribosomal protein L4 0.0259477
ACSL3 acyl-CoA synthetase long-chain family member 3 0.0259233
PTGES3 prostaglandin E synthase 3 (cytosolic) 0.0258803
HNRNPA2B1 heterogeneous nuclear ribonucleoprotein A2/B1 0.0257233
ATP2A2 ATPase, Ca++ transporting, cardiac muscle, slow twitch 2 0.0246861
IPO5 importin 5 0.0246166
CD55 CD55 molecule, decay accelerating factor for complement (Cromer blood group) 0.0246039
NSD1 nuclear receptor binding SET domain protein 1 0.0242585
SRP9 signal recognition particle 9kDa 0.024187
IGF2BP3 insulin-like growth factor 2 mRNA binding protein 3 0.0237893
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 0.0235054
LDHA lactate dehydrogenase A 0.0232262
PER1 period circadian clock 1 0.023226
ABL1 ABL proto-oncogene 1, non-receptor tyrosine kinase 0.023128
DYRK1A dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A 0.0226808
MMAB methylmalonic aciduria (cobalamin deficiency) cblB type 0.022433
RAB6A RAB6A, member RAS oncogene family 0.022423
PPIA peptidylprolyl isomerase A (cyclophilin A) 0.0224131
ALKBH5 AlkB family member 5, RNA demethylase 0.022367
YEATS2 YEATS domain containing 2 0.0222716
FXR1 fragile X mental retardation, autosomal homolog 1 0.0222695
COPG1 coatomer protein complex, subunit gamma 1 0.0221673
GLRX glutaredoxin (thioltransferase) 0.0221479
EEF1A1 eukaryotic translation elongation factor 1 alpha 1 0.0220946
EPB41L2 erythrocyte membrane protein band 4.1-like 2 0.0220705
SEC23A Sec23 homolog A (S. cerevisiae) 0.0219873
BIRC3 baculoviral IAP repeat containing 3 0.0219571
PARP8 poly (ADP-ribose) polymerase family, member 8 0.0219374
MORF4L1 mortality factor 4 like 1 0.0216625
FOXO3 forkhead box O3 0.0215016
ATL3 atlastin GTPase 3 0.0212716
MKI67 marker of proliferation Ki-67 0.0212506
NGLY1 N-glycanase 1 0.0212216
DIAPH3 diaphanous-related formin 3 0.0209611
RAD21 RAD21 homolog (S. pombe) 0.020869
CRYBG3 beta-gamma crystallin domain containing 3 0.0207864
APOLD1 apolipoprotein L domain containing 1 0.0207647
CD59 CD59 molecule, complement regulatory protein 0.0207586
KLF6 Kruppel-like factor 6 0.020715
UBC ubiquitin C 0.0206428
RAB8B RAB8B, member RAS oncogene family 0.0205348
CCDC88A coiled-coil domain containing 88A 0.0205048
RPS18 ribosomal protein S18 0.0204861

decreased expression

Symbol Name Standardized Value
VIM vimentin -0.157562
TMSB10 thymosin beta 10 -0.0703043
PTMA prothymosin, alpha -0.0647293
DSCAM Down syndrome cell adhesion molecule -0.0601639
GAPDH glyceraldehyde-3-phosphate dehydrogenase -0.0566882
ANXA2 annexin A2 -0.0546664
SETX senataxin -0.051693
PPFIA1 protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 1 -0.0499119
TPT1 tumor protein, translationally-controlled 1 -0.0493248
S100A10 S100 calcium binding protein A10 -0.047666
RPL35A ribosomal protein L35a -0.0471939
MBD5 methyl-CpG binding domain protein 5 -0.0455789
NEDD4 neural precursor cell expressed, developmentally down-regulated 4, E3 ubiquitin protein ligase -0.0435882
N4BP2L2 NEDD4 binding protein 2-like 2 -0.0414608
RAI14 retinoic acid induced 14 -0.0400136
IGFBP3 insulin-like growth factor binding protein 3 -0.0395197
RPLP1 ribosomal protein, large, P1 -0.0394483
RIGI RNA sensor RIG-I -0.0390783
RPS8 ribosomal protein S8 -0.0390744
LRRFIP1 leucine rich repeat (in FLII) interacting protein 1 -0.0390313
RAB1A RAB1A, member RAS oncogene family -0.0390014
NF1 neurofibromin 1 -0.0387792
SMYD3 SET and MYND domain containing 3 -0.0380224
HERC4 HECT and RLD domain containing E3 ubiquitin protein ligase 4 -0.0377657
HMGA2 high mobility group AT-hook 2 -0.0377373
SLC25A37 solute carrier family 25 (mitochondrial iron transporter), member 37 -0.0370071
RPL37A ribosomal protein L37a -0.0369029
NCEH1 neutral cholesterol ester hydrolase 1 -0.0365066
ASPH aspartate beta-hydroxylase -0.0364913
PNRC1 proline-rich nuclear receptor coactivator 1 -0.0364723
SERPINE2 serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 -0.0351105
RPL31 ribosomal protein L31 -0.0350122
IFIH1 interferon induced with helicase C domain 1 -0.0337762
TGFBR2 transforming growth factor, beta receptor II (70/80kDa) -0.0330259
RPLP0 ribosomal protein, large, P0 -0.0321936
RORA RAR-related orphan receptor A -0.0319215
S100A9 S100 calcium binding protein A9 -0.0308474
B2M beta-2-microglobulin -0.0307804
RPL12 ribosomal protein L12 -0.030673
LGALS1 lectin, galactoside-binding, soluble, 1 -0.0305713
ARID4B AT rich interactive domain 4B (RBP1-like) -0.0305223
BASP1 brain abundant, membrane attached signal protein 1 -0.0303283
RPL36 ribosomal protein L36 -0.0299703
ZC3HAV1 zinc finger CCCH-type, antiviral 1 -0.0294739
GNAS GNAS complex locus -0.0292717
HLA-C major histocompatibility complex, class I, C -0.0291332
RDX radixin -0.0290271
ACTG1 actin gamma 1 -0.0288043
IGF1R insulin-like growth factor 1 receptor -0.0285608
TAS2R14 taste receptor, type 2, member 14 -0.028412
RPL30 ribosomal protein L30 -0.0282712
ERC2 ELKS/RAB6-interacting/CAST family member 2 -0.0278501
ZSWIM6 zinc finger, SWIM-type containing 6 -0.0274841
KTN1 kinectin 1 (kinesin receptor) -0.02736
ANKRD12 ankyrin repeat domain 12 -0.0270665
MT2A metallothionein 2A -0.0269891
RPS23 ribosomal protein S23 -0.0268406
MTHFD1L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1-like -0.0268276
HM13 histocompatibility (minor) 13 -0.0265337
HMGB1 high mobility group box 1 -0.0264354
DHX34 DEAH (Asp-Glu-Ala-His) box polypeptide 34 -0.026304
RPL35 ribosomal protein L35 -0.0261845
BTG1 B-cell translocation gene 1, anti-proliferative -0.0261671
BDP1 B double prime 1, subunit of RNA polymerase III transcription initiation factor IIIB -0.0261665
TTC3 tetratricopeptide repeat domain 3 -0.0258081
NIPBL Nipped-B homolog (Drosophila) -0.0256987
CEP290 centrosomal protein 290kDa -0.0254984
DPYD dihydropyrimidine dehydrogenase -0.0252855
CALM2 calmodulin 2 (phosphorylase kinase, delta) -0.0251957
CEP350 centrosomal protein 350kDa -0.0250229
NFKBIZ nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta -0.0246451
POLR2A polymerase (RNA) II (DNA directed) polypeptide A, 220kDa -0.024481
CRIM1 cysteine rich transmembrane BMP regulator 1 (chordin-like) -0.024436
RPL23 ribosomal protein L23 -0.0242652
GOLGB1 golgin B1 -0.0241578
ITSN2 intersectin 2 -0.0240469
KRIT1 KRIT1, ankyrin repeat containing -0.0238192
HNRNPC heterogeneous nuclear ribonucleoprotein C (C1/C2) -0.0236048
CBL Cbl proto-oncogene, E3 ubiquitin protein ligase -0.0235776
EGR1 early growth response 1 -0.0235518
EGFR epidermal growth factor receptor -0.0233686
SEMA4B sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4B -0.0233337
RPS29 ribosomal protein S29 -0.0231736
ZFAND3 zinc finger, AN1-type domain 3 -0.023135
GPATCH2L G patch domain containing 2-like -0.0230064
SH3KBP1 SH3-domain kinase binding protein 1 -0.0228826
NALCN sodium leak channel, non selective -0.0227438
BCKDHB branched chain keto acid dehydrogenase E1, beta polypeptide -0.0226712
PRH1 proline-rich protein HaeIII subfamily 1 -0.0226545
KMT2A lysine (K)-specific methyltransferase 2A -0.0226202
VPS13A vacuolar protein sorting 13 homolog A (S. cerevisiae) -0.0222021
EIF2S2 eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa -0.0221802
EIF1 eukaryotic translation initiation factor 1 -0.0220749
PRSS23 protease, serine, 23 -0.0219908
NBEA neurobeachin -0.0219802
IFIT2 interferon-induced protein with tetratricopeptide repeats 2 -0.0219219
GCC2 GRIP and coiled-coil domain containing 2 -0.0218441
FER fer (fps/fes related) tyrosine kinase -0.0217313
BICD1 bicaudal D homolog 1 (Drosophila) -0.0216909
FAM3C family with sequence similarity 3, member C -0.0216456