Degeneration Of Lumbar Intervertebral Disc Gene Set

Dataset DisGeNET Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link https://www.disgenet.org/browser/0/1/0/C0263874
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Genes

47 genes associated with the disease Degeneration Of Lumbar Intervertebral Disc in GWAS and other genetic association datasets from the DisGeNET Gene-Disease Associations dataset.

Symbol Name
ACAN aggrecan
ADAMTS3 ADAM metallopeptidase with thrombospondin type 1 motif, 3
ADAMTS4 ADAM metallopeptidase with thrombospondin type 1 motif, 4
ADAMTS5 ADAM metallopeptidase with thrombospondin type 1 motif, 5
AKT1 v-akt murine thymoma viral oncogene homolog 1
AKT2 v-akt murine thymoma viral oncogene homolog 2
ASPN asporin
CCN2 cellular communication network factor 2
CDKN2A cyclin-dependent kinase inhibitor 2A
CHST3 carbohydrate (chondroitin 6) sulfotransferase 3
CILP cartilage intermediate layer protein, nucleotide pyrophosphohydrolase
COL11A1 collagen, type XI, alpha 1
COL1A1 collagen, type I, alpha 1
COL9A2 collagen, type IX, alpha 2
COL9A3 collagen, type IX, alpha 3
CSF2 colony stimulating factor 2 (granulocyte-macrophage)
FAS Fas cell surface death receptor
FGFR1 fibroblast growth factor receptor 1
FGFR3 fibroblast growth factor receptor 3
GDF5 growth differentiation factor 5
GSR glutathione reductase
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor)
IL10 interleukin 10
IL18RAP interleukin 18 receptor accessory protein
IL1A interleukin 1, alpha
IL1B interleukin 1, beta
IL4 interleukin 4
IL6 interleukin 6
LAMC2 laminin, gamma 2
LEP leptin
MMP1 matrix metallopeptidase 1
MMP13 matrix metallopeptidase 13
MMP2 matrix metallopeptidase 2
MMP3 matrix metallopeptidase 3
NOS3 nitric oxide synthase 3 (endothelial cell)
PPM1D protein phosphatase, Mg2+/Mn2+ dependent, 1D
PTK2B protein tyrosine kinase 2 beta
SIRT1 sirtuin 1
TGFB1 transforming growth factor, beta 1
TNF tumor necrosis factor
TNFRSF10A tumor necrosis factor receptor superfamily, member 10a
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10
TP53 tumor protein p53
TRPC3 transient receptor potential cation channel, subfamily C, member 3
TSLP thymic stromal lymphopoietin
VDR vitamin D (1,25- dihydroxyvitamin D3) receptor
VEGFA vascular endothelial growth factor A