Dehydration Gene Set

Dataset CTD Gene-Disease Associations
Category disease or phenotype associations
Type disease
External Link http://ctdbase.org/detail.go?type=disease&acc=MESH:D003681
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Genes

213 genes/proteins associated with the disease Dehydration from the curated CTD Gene-Disease Associations dataset.

Symbol Name Standardized Value
AVP arginine vasopressin 2.88009
TNFSF10 tumor necrosis factor (ligand) superfamily, member 10 1.8464
CASP8 caspase 8, apoptosis-related cysteine peptidase 1.72219
BIRC5 baculoviral IAP repeat containing 5 1.67654
BCL2L1 BCL2-like 1 1.66339
XIAP X-linked inhibitor of apoptosis, E3 ubiquitin protein ligase 1.64618
TYMP thymidine phosphorylase 1.63473
BCL2 B-cell CLL/lymphoma 2 1.62848
EGFR epidermal growth factor receptor 1.59638
CDK1 cyclin-dependent kinase 1 1.58607
CCND1 cyclin D1 1.58113
BAX BCL2-associated X protein 1.57114
CASP3 caspase 3, apoptosis-related cysteine peptidase 1.56632
FLT1 fms-related tyrosine kinase 1 1.54986
CCNB1 cyclin B1 1.54257
CASP9 caspase 9, apoptosis-related cysteine peptidase 1.54208
ABCC2 ATP-binding cassette, sub-family C (CFTR/MRP), member 2 1.53892
MCL1 myeloid cell leukemia 1 1.5284
CASP6 caspase 6, apoptosis-related cysteine peptidase 1.52086
MDM2 MDM2 proto-oncogene, E3 ubiquitin protein ligase 1.51784
CFLAR CASP8 and FADD-like apoptosis regulator 1.50223
NFKBIA nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha 1.50223
MAPK3 mitogen-activated protein kinase 3 1.492
CHEK2 checkpoint kinase 2 1.49174
VEGFA vascular endothelial growth factor A 1.47634
PMAIP1 phorbol-12-myristate-13-acetate-induced protein 1 1.46542
TYMS thymidylate synthetase 1.44219
AKT1 v-akt murine thymoma viral oncogene homolog 1 1.43837
BIRC3 baculoviral IAP repeat containing 3 1.43212
CDKN1B cyclin-dependent kinase inhibitor 1B (p27, Kip1) 1.43048
CDKN1A cyclin-dependent kinase inhibitor 1A (p21, Cip1) 1.4294
ABCB1 ATP-binding cassette, sub-family B (MDR/TAP), member 1 1.42183
RB1 retinoblastoma 1 1.41285
ARL6IP5 ADP-ribosylation factor-like 6 interacting protein 5 1.41202
H2AFX H2A histone family, member X 1.40925
BAD BCL2-associated agonist of cell death 1.40815
CASP4 caspase 4, apoptosis-related cysteine peptidase 1.4065
SERPINB5 serpin peptidase inhibitor, clade B (ovalbumin), member 5 1.40176
MMP9 matrix metallopeptidase 9 1.4012
FGF2 fibroblast growth factor 2 (basic) 1.40036
ALB albumin 1.39869
HIF1A hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) 1.39674
ALDH1A1 aldehyde dehydrogenase 1 family, member A1 1.38891
MAPK1 mitogen-activated protein kinase 1 1.37817
HSPB1 heat shock 27kDa protein 1 1.37761
IL6 interleukin 6 1.37504
BBC3 BCL2 binding component 3 1.37075
THBS1 thrombospondin 1 1.37075
DDIT3 DNA-damage-inducible transcript 3 1.3699
CCNE1 cyclin E1 1.36961
TP53 tumor protein p53 1.3682
BID BH3 interacting domain death agonist 1.36677
BIRC2 baculoviral IAP repeat containing 2 1.36133
BCL2L11 BCL2-like 11 (apoptosis facilitator) 1.36133
TXNIP thioredoxin interacting protein 1.35531
CDK2 cyclin-dependent kinase 2 1.35242
FN1 fibronectin 1 1.34869
INSIG1 insulin induced gene 1 1.34782
BRCA1 breast cancer 1, early onset 1.34635
BAK1 BCL2-antagonist/killer 1 1.34489
UGT1A1 UDP glucuronosyltransferase 1 family, polypeptide A1 1.3414
ABCC1 ATP-binding cassette, sub-family C (CFTR/MRP), member 1 1.33257
SP1 Sp1 transcription factor 1.32816
ID2 inhibitor of DNA binding 2, dominant negative helix-loop-helix protein 1.32518
ATM ATM serine/threonine kinase 1.32399
MYC v-myc avian myelocytomatosis viral oncogene homolog 1.31626
PECAM1 platelet/endothelial cell adhesion molecule 1 1.31566
IL10 interleukin 10 1.3085
CASP7 caspase 7, apoptosis-related cysteine peptidase 1.30727
GADD45A growth arrest and DNA-damage-inducible, alpha 1.29996
SAT1 spermidine/spermine N1-acetyltransferase 1 1.29966
CXCL8 chemokine (C-X-C motif) ligand 8 1.29564
MT1A metallothionein 1A 1.2944
IL1B interleukin 1, beta 1.29317
NFE2L2 nuclear factor, erythroid 2-like 2 1.2895
TNFRSF1A tumor necrosis factor receptor superfamily, member 1A 1.2821
SRPX sushi-repeat containing protein, X-linked 1.27905
MAP2K1 mitogen-activated protein kinase kinase 1 1.27533
HDAC1 histone deacetylase 1 1.27224
PLAT plasminogen activator, tissue 1.26514
IL18 interleukin 18 1.26514
TGFB1 transforming growth factor, beta 1 1.26113
FAS Fas cell surface death receptor 1.2596
DPYD dihydropyrimidine dehydrogenase 1.25929
FASLG Fas ligand (TNF superfamily, member 6) 1.25557
HDAC4 histone deacetylase 4 1.25525
CEBPB CCAAT/enhancer binding protein (C/EBP), beta 1.25121
CDK4 cyclin-dependent kinase 4 1.2368
SPARC secreted protein, acidic, cysteine-rich (osteonectin) 1.23424
CASP2 caspase 2, apoptosis-related cysteine peptidase 1.22758
SOD2 superoxide dismutase 2, mitochondrial 1.22664
PARP1 poly (ADP-ribose) polymerase 1 1.22242
BCL2L2 BCL2-like 2 1.2208
TNF tumor necrosis factor 1.21984
CCNA2 cyclin A2 1.21823
APAF1 apoptotic peptidase activating factor 1 1.21468
RAC1 ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) 1.20978
TGFA transforming growth factor, alpha 1.20816
ATF3 activating transcription factor 3 1.20526
MAPK14 mitogen-activated protein kinase 14 1.20427
IFNG interferon, gamma 1.2013
ERCC2 excision repair cross-complementation group 2 1.19933
CSF3 colony stimulating factor 3 (granulocyte) 1.1977
CCND3 cyclin D3 1.19607
NFKB1 nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 1.19542
GAMT guanidinoacetate N-methyltransferase 1.1908
TGFB2 transforming growth factor, beta 2 1.18882
MAP2K3 mitogen-activated protein kinase kinase 3 1.18489
FOS FBJ murine osteosarcoma viral oncogene homolog 1.18193
SGK1 serum/glucocorticoid regulated kinase 1 1.18059
GSK3B glycogen synthase kinase 3 beta 1.17662
GSTP1 glutathione S-transferase pi 1 1.1753
ERBB2 erb-b2 receptor tyrosine kinase 2 1.17497
ITGB4 integrin, beta 4 1.17134
MGMT O-6-methylguanine-DNA methyltransferase 1.17101
UGT1A6 UDP glucuronosyltransferase 1 family, polypeptide A6 1.167
CAV1 caveolin 1, caveolae protein, 22kDa 1.16567
TIMP2 TIMP metallopeptidase inhibitor 2 1.16035
RELA v-rel avian reticuloendotheliosis viral oncogene homolog A 1.15763
TNFRSF10B tumor necrosis factor receptor superfamily, member 10b 1.15256
GLRX glutaredoxin (thioltransferase) 1.15189
MYB v-myb avian myeloblastosis viral oncogene homolog 1.14954
CASP1 caspase 1, apoptosis-related cysteine peptidase 1.14885
HSPA5 heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) 1.14575
GSTA4 glutathione S-transferase alpha 4 1.14268
MAP2 microtubule-associated protein 2 1.14234
VCAM1 vascular cell adhesion molecule 1 1.14098
ADAMTS1 ADAM metallopeptidase with thrombospondin type 1 motif, 1 1.13827
AKT2 v-akt murine thymoma viral oncogene homolog 2 1.13518
SLC22A7 solute carrier family 22 (organic anion transporter), member 7 1.13381
MTOR mechanistic target of rapamycin (serine/threonine kinase) 1.13211
GSTM1 glutathione S-transferase mu 1 1.13177
EP300 E1A binding protein p300 1.13109
DKK1 dickkopf WNT signaling pathway inhibitor 1 1.12872
HMOX1 heme oxygenase 1 1.12634
SRC SRC proto-oncogene, non-receptor tyrosine kinase 1.1253
GSTT1 glutathione S-transferase theta 1 1.12391
MCM4 minichromosome maintenance complex component 4 1.12048
EGR1 early growth response 1 1.11877
PXDN peroxidasin 1.11877
MAP2K6 mitogen-activated protein kinase kinase 6 1.11843
PSAT1 phosphoserine aminotransferase 1 1.11843
STAT3 signal transducer and activator of transcription 3 (acute-phase response factor) 1.11809
CDKN2A cyclin-dependent kinase inhibitor 2A 1.11639
CTGF connective tissue growth factor 1.11536
NOS2 nitric oxide synthase 2, inducible 1.11501
IL1A interleukin 1, alpha 1.11466
GDF15 growth differentiation factor 15 1.10977
CCNG2 cyclin G2 1.10631
GJA1 gap junction protein, alpha 1, 43kDa 1.10424
JUN jun proto-oncogene 1.10353
MPO myeloperoxidase 1.10246
DIABLO diablo, IAP-binding mitochondrial protein 1.10246
G0S2 G0/G1 switch 2 1.09506
ERCC1 excision repair cross-complementation group 1 1.09506
AARS alanyl-tRNA synthetase 1.09506
AURKA aurora kinase A 1.08372
ABCG2 ATP-binding cassette, sub-family G (WHITE), member 2 (Junior blood group) 1.08372
NOTCH1 notch 1 1.08266
IL4 interleukin 4 1.08196
MMP2 matrix metallopeptidase 2 1.08196
HSPA1A heat shock 70kDa protein 1A 1.07983
TPMT thiopurine S-methyltransferase 1.07553
KCTD12 potassium channel tetramerization domain containing 12 1.07482
SLC22A8 solute carrier family 22 (organic anion transporter), member 8 1.0734
CYLD cylindromatosis (turban tumor syndrome) 1.07057
PTGS1 prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase) 1.06771
CD274 CD274 molecule 1.06734
RRAS related RAS viral (r-ras) oncogene homolog 1.06698
CCL3 chemokine (C-C motif) ligand 3 1.06479
HIST1H4C histone cluster 1, H4c 1.06333
PDCD5 programmed cell death 5 1.06297
PTGS2 prostaglandin-endoperoxide synthase 2 (prostaglandin G/H synthase and cyclooxygenase) 1.06225
CREBBP CREB binding protein 1.05972
XRCC6 X-ray repair complementing defective repair in Chinese hamster cells 6 1.05936
CES2 carboxylesterase 2 1.05828
RPS6 ribosomal protein S6 1.05685
LGALS3 lectin, galactoside-binding, soluble, 3 1.05648
TCF7L2 transcription factor 7-like 2 (T-cell specific, HMG-box) 1.05573
TRAP1 TNF receptor-associated protein 1 1.05573
LGALS8 lectin, galactoside-binding, soluble, 8 1.05274
CYP3A4 cytochrome P450, family 3, subfamily A, polypeptide 4 1.052
BNIP3 BCL2/adenovirus E1B 19kDa interacting protein 3 1.05015
RGS2 regulator of G-protein signaling 2 1.04868
PLA2G4A phospholipase A2, group IVA (cytosolic, calcium-dependent) 1.04831
THBS2 thrombospondin 2 1.04611
PRKCB protein kinase C, beta 1.04538
CCL2 chemokine (C-C motif) ligand 2 1.04501
ERBB4 erb-b2 receptor tyrosine kinase 4 1.04501
PTK2 protein tyrosine kinase 2 1.04088
ANXA2 annexin A2 1.04088
COL4A2 collagen, type IV, alpha 2 1.03827
KAT2B K(lysine) acetyltransferase 2B 1.03827
CYBB cytochrome b-245, beta polypeptide 1.03752
GPX1 glutathione peroxidase 1 1.03493
DUSP6 dual specificity phosphatase 6 1.03456
CHI3L1 chitinase 3-like 1 (cartilage glycoprotein-39) 1.03456
TERT telomerase reverse transcriptase 1.03456
CCNG1 cyclin G1 1.03308
TP53INP1 tumor protein p53 inducible nuclear protein 1 1.02896
IRS1 insulin receptor substrate 1 1.02708
GFRA1 GDNF family receptor alpha 1 1.02522
CTNNB1 catenin (cadherin-associated protein), beta 1, 88kDa 1.02188
CXCL1 chemokine (C-X-C motif) ligand 1 (melanoma growth stimulating activity, alpha) 1.02114
COL3A1 collagen, type III, alpha 1 1.0204
CD24 CD24 molecule 1.02003
IL1RN interleukin 1 receptor antagonist 1.01852
SPP1 secreted phosphoprotein 1 1.01625
ANKRD1 ankyrin repeat domain 1 (cardiac muscle) 1.01625
XRCC3 X-ray repair complementing defective repair in Chinese hamster cells 3 1.01587
TIMP1 TIMP metallopeptidase inhibitor 1 1.01549
TOB1 transducer of ERBB2, 1 1.01062
TLR3 toll-like receptor 3 1.01025