Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130 Gene Set

Dataset GEO Signatures of Differentially Expressed Genes for Diseases
Category transcriptomics
Type disease perturbation
Description disease perturbation identified as [disease]_[tissue]_[GEO accession] (Gene Expression Omnibus)
External Link http://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE4130
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Genes

600 genes differentially expressed during Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130 disease perturbation from the GEO Signatures of Differentially Expressed Genes for Diseases dataset.

increased expression

Symbol Name Standardized Value
PRPF8 pre-mRNA processing factor 8 3.78457
NDUFB11 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 11, 17.3kDa 3.76208
BRK1 BRICK1, SCAR/WAVE actin-nucleating complex subunit 3.21097
VDAC2 voltage-dependent anion channel 2 3.17894
MSRB1 methionine sulfoxide reductase B1 3.16717
NHP2 NHP2 ribonucleoprotein 3.09647
APMAP adipocyte plasma membrane associated protein 3.04609
FNTA farnesyltransferase, CAAX box, alpha 3.04581
LSM4 LSM4 homolog, U6 small nuclear RNA associated (S. cerevisiae) 2.96919
NDUFB2 NADH dehydrogenase (ubiquinone) 1 beta subcomplex, 2, 8kDa 2.95716
CLTA clathrin, light chain A 2.9229
POMP proteasome maturation protein 2.91485
MRPL43 mitochondrial ribosomal protein L43 2.91336
PSMD6 proteasome (prosome, macropain) 26S subunit, non-ATPase, 6 2.90446
ZNHIT6 zinc finger, HIT-type containing 6 2.87292
SRP68 signal recognition particle 68kDa 2.87272
SAT1 spermidine/spermine N1-acetyltransferase 1 2.8714
ICT1 immature colon carcinoma transcript 1 2.87091
TM2D3 TM2 domain containing 3 2.85876
TIMM13 translocase of inner mitochondrial membrane 13 homolog (yeast) 2.85127
SUMO3 small ubiquitin-like modifier 3 2.85032
MRPS18A mitochondrial ribosomal protein S18A 2.84376
RAB28 RAB28, member RAS oncogene family 2.84031
TXN thioredoxin 2.83643
RALGAPB Ral GTPase activating protein, beta subunit (non-catalytic) 2.82687
PSMA6 proteasome (prosome, macropain) subunit, alpha type, 6 2.82426
LCMT1 leucine carboxyl methyltransferase 1 2.79754
PRNP prion protein 2.78903
TCP1 t-complex 1 2.78782
SLC25A5 solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 2.78549
UPP1 uridine phosphorylase 1 2.77616
HSPD1 heat shock 60kDa protein 1 (chaperonin) 2.76293
SLC7A6OS solute carrier family 7, member 6 opposite strand 2.73712
COPG1 coatomer protein complex, subunit gamma 1 2.73214
C12ORF57 chromosome 12 open reading frame 57 2.72984
NGRN neugrin, neurite outgrowth associated 2.72428
NKAP NFKB activating protein 2.72382
SCCPDH saccharopine dehydrogenase (putative) 2.71501
COX7A2 cytochrome c oxidase subunit VIIa polypeptide 2 (liver) 2.68247
MRPL19 mitochondrial ribosomal protein L19 2.63935
CTSS cathepsin S 2.60186
UBE2L3 ubiquitin-conjugating enzyme E2L 3 2.59407
NCKAP1 NCK-associated protein 1 2.57786
HERPUD2 HERPUD family member 2 2.54017
DHPS deoxyhypusine synthase 2.53547
VPS28 vacuolar protein sorting 28 homolog (S. cerevisiae) 2.53396
SDF2 stromal cell-derived factor 2 2.51388
SLC43A2 solute carrier family 43 (amino acid system L transporter), member 2 2.50887
STRAP serine/threonine kinase receptor associated protein 2.49257
PDE9A phosphodiesterase 9A 2.48083
MRPL41 mitochondrial ribosomal protein L41 2.47185
TOMM6 translocase of outer mitochondrial membrane 6 homolog (yeast) 2.47076
POMGNT1 protein O-linked mannose N-acetylglucosaminyltransferase 1 (beta 1,2-) 2.45578
ATG4B autophagy related 4B, cysteine peptidase 2.45397
PSMA7 proteasome (prosome, macropain) subunit, alpha type, 7 2.43476
SWI5 SWI5 recombination repair homolog (yeast) 2.42755
PHAX phosphorylated adaptor for RNA export 2.42057
PHF23 PHD finger protein 23 2.41453
SCAF4 SR-related CTD-associated factor 4 2.40861
AIMP1 aminoacyl tRNA synthetase complex-interacting multifunctional protein 1 2.39777
FIBP fibroblast growth factor (acidic) intracellular binding protein 2.38982
CLPP caseinolytic mitochondrial matrix peptidase proteolytic subunit 2.37588
ATP5D ATP synthase, H+ transporting, mitochondrial F1 complex, delta subunit 2.37425
DCTN3 dynactin 3 (p22) 2.37236
CITED2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 2.36522
PPAN peter pan homolog (Drosophila) 2.36295
DDX1 DEAD (Asp-Glu-Ala-Asp) box helicase 1 2.35859
UBXN6 UBX domain protein 6 2.35547
PSMF1 proteasome (prosome, macropain) inhibitor subunit 1 (PI31) 2.35262
NDUFA7 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 7, 14.5kDa 2.34988
ACOT9 acyl-CoA thioesterase 9 2.32455
NEDD8 neural precursor cell expressed, developmentally down-regulated 8 2.293
NAA20 N(alpha)-acetyltransferase 20, NatB catalytic subunit 2.26749
HN1 hematological and neurological expressed 1 2.26591
RAN RAN, member RAS oncogene family 2.26059
UBA2 ubiquitin-like modifier activating enzyme 2 2.25525
ATP5G3 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit C3 (subunit 9) 2.24566
HMGCS2 3-hydroxy-3-methylglutaryl-CoA synthase 2 (mitochondrial) 2.24476
TNPO3 transportin 3 2.22853
CD81 CD81 molecule 2.2219
GRPEL1 GrpE-like 1, mitochondrial (E. coli) 2.22042
MALSU1 mitochondrial assembly of ribosomal large subunit 1 2.21614
ATP5J2 ATP synthase, H+ transporting, mitochondrial Fo complex, subunit F2 2.21529
PSMB3 proteasome (prosome, macropain) subunit, beta type, 3 2.20819
TXNDC16 thioredoxin domain containing 16 2.20516
UTP3 UTP3, small subunit (SSU) processome component, homolog (S. cerevisiae) 2.20421
FTH1 ferritin, heavy polypeptide 1 2.19541
SURF2 surfeit 2 2.19127
DDX47 DEAD (Asp-Glu-Ala-Asp) box polypeptide 47 2.18547
HEPH hephaestin 2.18327
ASNS asparagine synthetase (glutamine-hydrolyzing) 2.17825
ELOF1 elongation factor 1 homolog (S. cerevisiae) 2.17694
DNAJC8 DnaJ (Hsp40) homolog, subfamily C, member 8 2.17644
UQCRB ubiquinol-cytochrome c reductase binding protein 2.16908
PPIA peptidylprolyl isomerase A (cyclophilin A) 2.16717
DHX38 DEAH (Asp-Glu-Ala-His) box polypeptide 38 2.15504
STOML2 stomatin (EPB72)-like 2 2.14975
DHTKD1 dehydrogenase E1 and transketolase domain containing 1 2.14947
GABPB1 GA binding protein transcription factor, beta subunit 1 2.14442
ZGPAT zinc finger, CCCH-type with G patch domain 2.14145
HIGD1B HIG1 hypoxia inducible domain family, member 1B 2.13157
COX18 COX18 cytochrome c oxidase assembly factor 2.12853
HSPA8 heat shock 70kDa protein 8 2.11924
BAX BCL2-associated X protein 2.11219
HYPK huntingtin interacting protein K 2.11041
TCEB1 transcription elongation factor B (SIII), polypeptide 1 (15kDa, elongin C) 2.1101
MRPL28 mitochondrial ribosomal protein L28 2.10467
SPATS2L spermatogenesis associated, serine-rich 2-like 2.09936
VPS11 vacuolar protein sorting 11 homolog (S. cerevisiae) 2.09896
PIAS2 protein inhibitor of activated STAT, 2 2.09636
COMMD3 COMM domain containing 3 2.09594
INO80C INO80 complex subunit C 2.09582
VPS45 vacuolar protein sorting 45 homolog (S. cerevisiae) 2.09138
TBCE tubulin folding cofactor E 2.08684
DDX23 DEAD (Asp-Glu-Ala-Asp) box polypeptide 23 2.07619
PSMB6 proteasome (prosome, macropain) subunit, beta type, 6 2.07591
TMEM184C transmembrane protein 184C 2.07497
ND1 2.07446
GPANK1 G patch domain and ankyrin repeats 1 2.07277
CLPX caseinolytic mitochondrial matrix peptidase chaperone subunit 2.07014
FKBP3 FK506 binding protein 3, 25kDa 2.06975
GTF2F1 general transcription factor IIF, polypeptide 1, 74kDa 2.06865
SSX2IP synovial sarcoma, X breakpoint 2 interacting protein 2.05862
FAM104A family with sequence similarity 104, member A 2.05335
ABHD10 abhydrolase domain containing 10 2.05065
HSPE1 heat shock 10kDa protein 1 2.04885
ACSL5 acyl-CoA synthetase long-chain family member 5 2.04796
COX4I1 cytochrome c oxidase subunit IV isoform 1 2.03747
COX7B cytochrome c oxidase subunit VIIb 2.03459
ATP6V0D1 ATPase, H+ transporting, lysosomal 38kDa, V0 subunit d1 2.02309
PSMA4 proteasome (prosome, macropain) subunit, alpha type, 4 2.02064
RANBP3 RAN binding protein 3 2.01619
MRPS24 mitochondrial ribosomal protein S24 2.00974
GATAD2A GATA zinc finger domain containing 2A 2.00131
ATP5A1 ATP synthase, H+ transporting, mitochondrial F1 complex, alpha subunit 1, cardiac muscle 1.99791
ABCG1 ATP-binding cassette, sub-family G (WHITE), member 1 1.99619
RGS10 regulator of G-protein signaling 10 1.99522
PRMT1 protein arginine methyltransferase 1 1.99405
NDUFV3 NADH dehydrogenase (ubiquinone) flavoprotein 3, 10kDa 1.9918
PSMC2 proteasome (prosome, macropain) 26S subunit, ATPase, 2 1.98706
PRDX5 peroxiredoxin 5 1.9848
PSMA5 proteasome (prosome, macropain) subunit, alpha type, 5 1.98143
MYEOV2 myeloma overexpressed 2 1.98107
CTPS2 CTP synthase 2 1.98084
MLYCD malonyl-CoA decarboxylase 1.97019
SUMO1 small ubiquitin-like modifier 1 1.96815
OGFR opioid growth factor receptor 1.95617
AIMP2 aminoacyl tRNA synthetase complex-interacting multifunctional protein 2 1.9553
ACBD6 acyl-CoA binding domain containing 6 1.94223
ANKS1B ankyrin repeat and sterile alpha motif domain containing 1B 1.93737
WDR26 WD repeat domain 26 1.9372
GNL3 guanine nucleotide binding protein-like 3 (nucleolar) 1.93554
TMEM128 transmembrane protein 128 1.93277
SF3B1 splicing factor 3b, subunit 1, 155kDa 1.92119
TYW3 tRNA-yW synthesizing protein 3 homolog (S. cerevisiae) 1.91751
TBK1 TANK-binding kinase 1 1.91735
CISD1 CDGSH iron sulfur domain 1 1.90498
SCNM1 sodium channel modifier 1 1.89969
PIGS phosphatidylinositol glycan anchor biosynthesis, class S 1.89911
MCRS1 microspherule protein 1 1.89374
PSMC6 proteasome (prosome, macropain) 26S subunit, ATPase, 6 1.8896
PDCD5 programmed cell death 5 1.88881
FAHD2B fumarylacetoacetate hydrolase domain containing 2B 1.88211
TIMM9 translocase of inner mitochondrial membrane 9 homolog (yeast) 1.87794
COQ4 coenzyme Q4 1.87559
RRP15 ribosomal RNA processing 15 homolog (S. cerevisiae) 1.87276
TRAP1 TNF receptor-associated protein 1 1.87032
TMEM80 transmembrane protein 80 1.86988
PSMD2 proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 1.86122
IMPA2 inositol(myo)-1(or 4)-monophosphatase 2 1.84801
KLF11 Kruppel-like factor 11 1.84739
SLC25A3 solute carrier family 25 (mitochondrial carrier; phosphate carrier), member 3 1.84706
CIB2 calcium and integrin binding family member 2 1.84275
SPRYD7 SPRY domain containing 7 1.84123
NDUFS8 NADH dehydrogenase (ubiquinone) Fe-S protein 8, 23kDa (NADH-coenzyme Q reductase) 1.83877
RAB24 RAB24, member RAS oncogene family 1.83834
MAST4 microtubule associated serine/threonine kinase family member 4 1.83409
EIF6 eukaryotic translation initiation factor 6 1.8315
ARMCX2 armadillo repeat containing, X-linked 2 1.82938
HIGD2A HIG1 hypoxia inducible domain family, member 2A 1.82788
FIS1 fission 1 (mitochondrial outer membrane) homolog (S. cerevisiae) 1.82574
ARL6 ADP-ribosylation factor-like 6 1.82543
MRFAP1 Morf4 family associated protein 1 1.82281
JTB jumping translocation breakpoint 1.82066
AKR1A1 aldo-keto reductase family 1, member A1 (aldehyde reductase) 1.81532
SLCO1C1 solute carrier organic anion transporter family, member 1C1 1.81436
SCO1 SCO1 cytochrome c oxidase assembly protein 1.80982
ACD adrenocortical dysplasia homolog (mouse) 1.79872
UQCRQ ubiquinol-cytochrome c reductase, complex III subunit VII, 9.5kDa 1.79692
SUCLG1 succinate-CoA ligase, alpha subunit 1.7957
TRMT6 tRNA methyltransferase 6 1.79206
VWA8 von Willebrand factor A domain containing 8 1.78086
TMEM5 transmembrane protein 5 1.77977
PAFAH1B2 platelet-activating factor acetylhydrolase 1b, catalytic subunit 2 (30kDa) 1.77571
CASC4 cancer susceptibility candidate 4 1.77332
DDRGK1 DDRGK domain containing 1 1.77308
RNMT RNA (guanine-7-) methyltransferase 1.77137
LY6E lymphocyte antigen 6 complex, locus E 1.76791
YWHAE tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, epsilon 1.76757
LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 1.76288
MYBBP1A MYB binding protein (P160) 1a 1.7595
RARS arginyl-tRNA synthetase 1.75861
SLC35B4 solute carrier family 35 (UDP-xylose/UDP-N-acetylglucosamine transporter), member B4 1.75663
UBA6 ubiquitin-like modifier activating enzyme 6 1.75373
ATP5B ATP synthase, H+ transporting, mitochondrial F1 complex, beta polypeptide 1.75168
DLD dihydrolipoamide dehydrogenase 1.74571
ZDHHC7 zinc finger, DHHC-type containing 7 1.74454
SFSWAP splicing factor, suppressor of white-apricot family 1.74434
MRPS35 mitochondrial ribosomal protein S35 1.74347
PITRM1 pitrilysin metallopeptidase 1 1.7425
UGDH UDP-glucose 6-dehydrogenase 1.74172
TRMT112 tRNA methyltransferase 11-2 homolog (S. cerevisiae) 1.74121
UBE2V2 ubiquitin-conjugating enzyme E2 variant 2 1.74101
ABCF1 ATP-binding cassette, sub-family F (GCN20), member 1 1.73826
ZRSR2 zinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2 1.73678
ASCC1 activating signal cointegrator 1 complex subunit 1 1.73605
TMEM138 transmembrane protein 138 1.73379
FAM175B family with sequence similarity 175, member B 1.73108
LONP2 lon peptidase 2, peroxisomal 1.72337
PNPLA7 patatin-like phospholipase domain containing 7 1.72224
MCFD2 multiple coagulation factor deficiency 2 1.72182
BAG1 BCL2-associated athanogene 1.72142
MB21D2 Mab-21 domain containing 2 1.72112
R3HDM1 R3H domain containing 1 1.71757
SAP30L SAP30-like 1.71753
RABAC1 Rab acceptor 1 (prenylated) 1.71311
EXOSC5 exosome component 5 1.71259
MAD2L1BP MAD2L1 binding protein 1.71113
HADHB hydroxyacyl-CoA dehydrogenase/3-ketoacyl-CoA thiolase/enoyl-CoA hydratase (trifunctional protein), beta subunit 1.70846
PARK7 parkinson protein 7 1.70018
ANAPC7 anaphase promoting complex subunit 7 1.69951
NAA10 N(alpha)-acetyltransferase 10, NatA catalytic subunit 1.69317
JMJD6 jumonji domain containing 6 1.69295
GRWD1 glutamate-rich WD repeat containing 1 1.68903
IPO4 importin 4 1.68804
MRPL1 mitochondrial ribosomal protein L1 1.68773
MRPL35 mitochondrial ribosomal protein L35 1.68748
DOLK dolichol kinase 1.68631
FAM118A family with sequence similarity 118, member A 1.68579
NAPA N-ethylmaleimide-sensitive factor attachment protein, alpha 1.67952
ARID1B AT rich interactive domain 1B (SWI1-like) 1.67922
RPF2 ribosome production factor 2 homolog (S. cerevisiae) 1.67179
CPSF7 cleavage and polyadenylation specific factor 7, 59kDa 1.66829
GLRX2 glutaredoxin 2 1.6678
USPL1 ubiquitin specific peptidase like 1 1.66557
CNOT10 CCR4-NOT transcription complex, subunit 10 1.66206
GRIK4 glutamate receptor, ionotropic, kainate 4 1.65558
NDUFC1 NADH dehydrogenase (ubiquinone) 1, subcomplex unknown, 1, 6kDa 1.65253
TMEM65 transmembrane protein 65 1.65248
CHCHD10 coiled-coil-helix-coiled-coil-helix domain containing 10 1.65191
MRPL33 mitochondrial ribosomal protein L33 1.64561
WBSCR22 Williams Beuren syndrome chromosome region 22 1.64218
TBL3 transducin (beta)-like 3 1.64205
STK24 serine/threonine kinase 24 1.64009
TXNDC12 thioredoxin domain containing 12 (endoplasmic reticulum) 1.63577
NDUFA2 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 2, 8kDa 1.63532
STX7 syntaxin 7 1.63416
ANAPC5 anaphase promoting complex subunit 5 1.63387
PSMD13 proteasome (prosome, macropain) 26S subunit, non-ATPase, 13 1.63283
MRPL21 mitochondrial ribosomal protein L21 1.63282
FLII flightless I homolog (Drosophila) 1.63211
EEF1D eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) 1.62757
BBC3 BCL2 binding component 3 1.62265
SSNA1 Sjogren syndrome nuclear autoantigen 1 1.62033
GALK2 galactokinase 2 1.61153
BCAP31 B-cell receptor-associated protein 31 1.60774
BUD13 BUD13 homolog (S. cerevisiae) 1.60668
ST8SIA3 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 3 1.60668
EIF2B4 eukaryotic translation initiation factor 2B, subunit 4 delta, 67kDa 1.60655
PLEKHA3 pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 3 1.60427
PPCS phosphopantothenoylcysteine synthetase 1.59384
MRPS28 mitochondrial ribosomal protein S28 1.59358
DGAT1 diacylglycerol O-acyltransferase 1 1.59217
STMN1 stathmin 1 1.59203
PTRH1 peptidyl-tRNA hydrolase 1 homolog (S. cerevisiae) 1.59189
ICMT isoprenylcysteine carboxyl methyltransferase 1.59146
SLC30A4 solute carrier family 30 (zinc transporter), member 4 1.59132
SEPHS2 selenophosphate synthetase 2 1.59035
ACP1 acid phosphatase 1, soluble 1.59003
PSMD7 proteasome (prosome, macropain) 26S subunit, non-ATPase, 7 1.5893
MINPP1 multiple inositol-polyphosphate phosphatase 1 1.58847
MIF macrophage migration inhibitory factor (glycosylation-inhibiting factor) 1.57878
COG1 component of oligomeric golgi complex 1 1.57862
VPS51 vacuolar protein sorting 51 homolog (S. cerevisiae) 1.57855
SMPD1 sphingomyelin phosphodiesterase 1, acid lysosomal 1.57282
ADCK5 aarF domain containing kinase 5 1.56815
PDSS2 prenyl (decaprenyl) diphosphate synthase, subunit 2 1.56577
RNF146 ring finger protein 146 1.56369
DDIT3 DNA-damage-inducible transcript 3 1.56316
OTUD7B OTU deubiquitinase 7B 1.56108
MRPL54 mitochondrial ribosomal protein L54 1.56002
ERCC3 excision repair cross-complementation group 3 1.55978
STUB1 STIP1 homology and U-box containing protein 1, E3 ubiquitin protein ligase 1.55975
CMSS1 cms1 ribosomal small subunit homolog (yeast) 1.55755
CSNK2B casein kinase 2, beta polypeptide 1.55678
VDAC3 voltage-dependent anion channel 3 1.55674
BRD9 bromodomain containing 9 1.55633
FANCE Fanconi anemia, complementation group E 1.55264
COX2 1.55083
TBRG4 transforming growth factor beta regulator 4 1.55006

decreased expression

Symbol Name Standardized Value
FADS1 fatty acid desaturase 1 -3.83595
EI24 etoposide induced 2.4 -2.98587
CIC capicua transcriptional repressor -2.80705
GNPDA1 glucosamine-6-phosphate deaminase 1 -2.62732
BBX bobby sox homolog (Drosophila) -2.61602
ZBTB4 zinc finger and BTB domain containing 4 -2.56181
SLC25A17 solute carrier family 25 (mitochondrial carrier; peroxisomal membrane protein, 34kDa), member 17 -2.5471
FKTN fukutin -2.46325
MED23 mediator complex subunit 23 -2.46253
SFPQ splicing factor proline/glutamine-rich -2.39085
SATB1 SATB homeobox 1 -2.37684
AGL amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase -2.37215
RDX radixin -2.35551
PABPN1 poly(A) binding protein, nuclear 1 -2.31624
ABCD3 ATP-binding cassette, sub-family D (ALD), member 3 -2.29671
FOXRED1 FAD-dependent oxidoreductase domain containing 1 -2.27357
TRIM24 tripartite motif containing 24 -2.27108
RB1CC1 RB1-inducible coiled-coil 1 -2.26375
TRIM41 tripartite motif containing 41 -2.25165
AMT aminomethyltransferase -2.23681
CDC42SE2 CDC42 small effector 2 -2.17083
ALG12 ALG12, alpha-1,6-mannosyltransferase -2.1436
PSAP prosaposin -2.14215
SAT2 spermidine/spermine N1-acetyltransferase family member 2 -2.1299
ZSWIM3 zinc finger, SWIM-type containing 3 -2.12161
FBXW4 F-box and WD repeat domain containing 4 -2.08852
RPL7L1 ribosomal protein L7-like 1 -2.08823
MMP15 matrix metallopeptidase 15 (membrane-inserted) -2.08817
CAT catalase -2.08102
SHARPIN SHANK-associated RH domain interactor -2.07813
SMARCB1 SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily b, member 1 -2.06801
SLC35E1 solute carrier family 35, member E1 -2.06715
DAB2IP DAB2 interacting protein -2.06467
PIGV phosphatidylinositol glycan anchor biosynthesis, class V -2.03989
LPCAT1 lysophosphatidylcholine acyltransferase 1 -2.03633
SCOC short coiled-coil protein -2.01422
STK40 serine/threonine kinase 40 -1.99204
FITM2 fat storage-inducing transmembrane protein 2 -1.95994
PLA2G6 phospholipase A2, group VI (cytosolic, calcium-independent) -1.95947
IPO9 importin 9 -1.95482
FBL fibrillarin -1.94483
TMEM47 transmembrane protein 47 -1.94294
PSMD14 proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 -1.94035
TRAK1 trafficking protein, kinesin binding 1 -1.93677
KLHDC1 kelch domain containing 1 -1.91961
DOCK1 dedicator of cytokinesis 1 -1.91603
RFK riboflavin kinase -1.91508
SMOC1 SPARC related modular calcium binding 1 -1.91456
CDC37L1 cell division cycle 37-like 1 -1.90662
GPC4 glypican 4 -1.90379
ZNF395 zinc finger protein 395 -1.90357
ZNF609 zinc finger protein 609 -1.89914
PYCR2 pyrroline-5-carboxylate reductase family, member 2 -1.89215
CDKN2AIPNL CDKN2A interacting protein N-terminal like -1.88801
TPRKB TP53RK binding protein -1.88787
GMPR2 guanosine monophosphate reductase 2 -1.88232
IPO7 importin 7 -1.86623
ZNF445 zinc finger protein 445 -1.84033
RGL1 ral guanine nucleotide dissociation stimulator-like 1 -1.8361
EIF4EBP2 eukaryotic translation initiation factor 4E binding protein 2 -1.8324
DPF2 D4, zinc and double PHD fingers family 2 -1.81496
SUCLG2 succinate-CoA ligase, GDP-forming, beta subunit -1.80346
AKAP7 A kinase (PRKA) anchor protein 7 -1.80178
VASN vasorin -1.79199
CCNT2 cyclin T2 -1.78045
HACD1 3-hydroxyacyl-CoA dehydratase 1 -1.77528
ZADH2 zinc binding alcohol dehydrogenase domain containing 2 -1.76886
LIMD2 LIM domain containing 2 -1.76694
RUNX1T1 runt-related transcription factor 1; translocated to, 1 (cyclin D-related) -1.76532
PACSIN2 protein kinase C and casein kinase substrate in neurons 2 -1.75793
SLC26A6 solute carrier family 26 (anion exchanger), member 6 -1.75749
SLU7 SLU7 splicing factor homolog (S. cerevisiae) -1.7476
FGD1 FYVE, RhoGEF and PH domain containing 1 -1.74453
AP3S2 adaptor-related protein complex 3, sigma 2 subunit -1.74197
NTAN1 N-terminal asparagine amidase -1.73335
HSP90AB1 heat shock protein 90kDa alpha (cytosolic), class B member 1 -1.73277
SETD8 SET domain containing (lysine methyltransferase) 8 -1.73049
FAM222B family with sequence similarity 222, member B -1.72709
WRNIP1 Werner helicase interacting protein 1 -1.72312
DPH3 diphthamide biosynthesis 3 -1.70467
USP48 ubiquitin specific peptidase 48 -1.70466
PSMD4 proteasome (prosome, macropain) 26S subunit, non-ATPase, 4 -1.7046
MTMR14 myotubularin related protein 14 -1.70017
BRD3 bromodomain containing 3 -1.69848
NOTCH1 notch 1 -1.69695
DPP8 dipeptidyl-peptidase 8 -1.69438
PHKB phosphorylase kinase, beta -1.69156
SEPT7 septin 7 -1.68624
RAB18 RAB18, member RAS oncogene family -1.67948
ZBTB44 zinc finger and BTB domain containing 44 -1.67935
SORD sorbitol dehydrogenase -1.67782
DARS2 aspartyl-tRNA synthetase 2, mitochondrial -1.67521
TOMM22 translocase of outer mitochondrial membrane 22 homolog (yeast) -1.67421
HIBADH 3-hydroxyisobutyrate dehydrogenase -1.66683
SEZ6 seizure related 6 homolog (mouse) -1.65185
RBMX RNA binding motif protein, X-linked -1.65071
MLLT10 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 -1.64807
MTMR6 myotubularin related protein 6 -1.63279
TBC1D14 TBC1 domain family, member 14 -1.6307
ARHGAP5 Rho GTPase activating protein 5 -1.62675
FAM71E1 family with sequence similarity 71, member E1 -1.62435
CCDC127 coiled-coil domain containing 127 -1.62211
USP36 ubiquitin specific peptidase 36 -1.61012
FASTK Fas-activated serine/threonine kinase -1.6045
PGM2 phosphoglucomutase 2 -1.60353
GGA1 golgi-associated, gamma adaptin ear containing, ARF binding protein 1 -1.60194
SNX19 sorting nexin 19 -1.60146
EHD1 EH-domain containing 1 -1.60084
EPS15 epidermal growth factor receptor pathway substrate 15 -1.58574
TFR2 transferrin receptor 2 -1.58035
SYT17 synaptotagmin XVII -1.57775
GORASP1 golgi reassembly stacking protein 1, 65kDa -1.57736
ZNF710 zinc finger protein 710 -1.566
SORL1 sortilin-related receptor, L(DLR class) A repeats containing -1.55862
ANKRD24 ankyrin repeat domain 24 -1.55671
ZBTB7C zinc finger and BTB domain containing 7C -1.55549
UBE3A ubiquitin protein ligase E3A -1.55452
CD302 CD302 molecule -1.55296
VTA1 vesicle (multivesicular body) trafficking 1 -1.55229
OXCT1 3-oxoacid CoA transferase 1 -1.55092
UAP1 UDP-N-acetylglucosamine pyrophosphorylase 1 -1.54913
MPHOSPH8 M-phase phosphoprotein 8 -1.54912
ELAVL1 ELAV like RNA binding protein 1 -1.54862
RPS6KA5 ribosomal protein S6 kinase, 90kDa, polypeptide 5 -1.54379
GDPD2 glycerophosphodiester phosphodiesterase domain containing 2 -1.54111
MAVS mitochondrial antiviral signaling protein -1.53472
CSNK1G2 casein kinase 1, gamma 2 -1.53311
ATP5J2-PTCD1 ATP5J2-PTCD1 readthrough -1.52642
NDUFV1 NADH dehydrogenase (ubiquinone) flavoprotein 1, 51kDa -1.52558
GADD45G growth arrest and DNA-damage-inducible, gamma -1.52487
IKZF4 IKAROS family zinc finger 4 (Eos) -1.52477
ACSS2 acyl-CoA synthetase short-chain family member 2 -1.5209
DSTYK dual serine/threonine and tyrosine protein kinase -1.51243
PPP1CB protein phosphatase 1, catalytic subunit, beta isozyme -1.51156
SDHC succinate dehydrogenase complex, subunit C, integral membrane protein, 15kDa -1.50926
MLLT3 myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 3 -1.50816
CHM choroideremia (Rab escort protein 1) -1.50343
CPM carboxypeptidase M -1.49716
ABHD4 abhydrolase domain containing 4 -1.49711
RFX4 regulatory factor X, 4 (influences HLA class II expression) -1.49476
ERCC2 excision repair cross-complementation group 2 -1.4859
GRB2 growth factor receptor-bound protein 2 -1.48444
STARD4 StAR-related lipid transfer (START) domain containing 4 -1.48207
RECQL RecQ helicase-like -1.4808
TNRC6A trinucleotide repeat containing 6A -1.47892
PCID2 PCI domain containing 2 -1.47839
SPAST spastin -1.47413
COG3 component of oligomeric golgi complex 3 -1.47138
TMEM97 transmembrane protein 97 -1.46649
WDR41 WD repeat domain 41 -1.46484
LRRC59 leucine rich repeat containing 59 -1.46313
SCN9A sodium channel, voltage gated, type IX alpha subunit -1.46292
PTDSS2 phosphatidylserine synthase 2 -1.46252
MRPL4 mitochondrial ribosomal protein L4 -1.45302
AFF4 AF4/FMR2 family, member 4 -1.44866
NUDT5 nudix (nucleoside diphosphate linked moiety X)-type motif 5 -1.44857
HS2ST1 heparan sulfate 2-O-sulfotransferase 1 -1.44835
HIVEP2 human immunodeficiency virus type I enhancer binding protein 2 -1.43892
NCOA1 nuclear receptor coactivator 1 -1.43643
ENSA endosulfine alpha -1.43454
CALCOCO1 calcium binding and coiled-coil domain 1 -1.43336
RBL2 retinoblastoma-like 2 -1.43065
TRPS1 trichorhinophalangeal syndrome I -1.42832
SMURF2 SMAD specific E3 ubiquitin protein ligase 2 -1.42811
CYHR1 cysteine/histidine-rich 1 -1.42067
TIMM22 translocase of inner mitochondrial membrane 22 homolog (yeast) -1.41943
ZSCAN21 zinc finger and SCAN domain containing 21 -1.41842
SH2B1 SH2B adaptor protein 1 -1.41549
ACACA acetyl-CoA carboxylase alpha -1.4096
ARAF A-Raf proto-oncogene, serine/threonine kinase -1.40848
NEO1 neogenin 1 -1.4078
TTC14 tetratricopeptide repeat domain 14 -1.40694
AP4B1 adaptor-related protein complex 4, beta 1 subunit -1.40014
SIDT2 SID1 transmembrane family, member 2 -1.39
CDH11 cadherin 11, type 2, OB-cadherin (osteoblast) -1.38503
ZFC3H1 zinc finger, C3H1-type containing -1.38367
ATP13A1 ATPase type 13A1 -1.38037
OXSR1 oxidative stress responsive 1 -1.37842
SPON1 spondin 1, extracellular matrix protein -1.37496
PANK1 pantothenate kinase 1 -1.37115
ZNF821 zinc finger protein 821 -1.37016
RNGTT RNA guanylyltransferase and 5'-phosphatase -1.3647
STT3A STT3A, subunit of the oligosaccharyltransferase complex (catalytic) -1.36313
PLCD4 phospholipase C, delta 4 -1.36172
ETFDH electron-transferring-flavoprotein dehydrogenase -1.36153
GMIP GEM interacting protein -1.36019
EIF4G3 eukaryotic translation initiation factor 4 gamma, 3 -1.36005
SVIP small VCP/p97-interacting protein -1.35794
UIMC1 ubiquitin interaction motif containing 1 -1.35675
CLK3 CDC-like kinase 3 -1.35589
ZDHHC3 zinc finger, DHHC-type containing 3 -1.35452
MYD88 myeloid differentiation primary response 88 -1.35347
RDH14 retinol dehydrogenase 14 (all-trans/9-cis/11-cis) -1.35294
TMEM14A transmembrane protein 14A -1.34794
RCC2 regulator of chromosome condensation 2 -1.34695
NACC2 NACC family member 2, BEN and BTB (POZ) domain containing -1.34682
PITPNB phosphatidylinositol transfer protein, beta -1.34058
PON2 paraoxonase 2 -1.33938
RBM4B RNA binding motif protein 4B -1.33828
RAB4A RAB4A, member RAS oncogene family -1.3378
YEATS2 YEATS domain containing 2 -1.33431
HK2 hexokinase 2 -1.33428
PARP1 poly (ADP-ribose) polymerase 1 -1.33194
HMGCR 3-hydroxy-3-methylglutaryl-CoA reductase -1.33063
MAP4K2 mitogen-activated protein kinase kinase kinase kinase 2 -1.33011
ACO1 aconitase 1, soluble -1.3282
FZD2 frizzled class receptor 2 -1.32807
ABCC5 ATP-binding cassette, sub-family C (CFTR/MRP), member 5 -1.32751
TRPC1 transient receptor potential cation channel, subfamily C, member 1 -1.32571
SLC37A4 solute carrier family 37 (glucose-6-phosphate transporter), member 4 -1.32225
HAUS1 HAUS augmin-like complex, subunit 1 -1.3193
NEURL2 neuralized E3 ubiquitin protein ligase 2 -1.31908
LACTB2 lactamase, beta 2 -1.31567
RAF1 Raf-1 proto-oncogene, serine/threonine kinase -1.31277
HACD3 3-hydroxyacyl-CoA dehydratase 3 -1.30905
AP5M1 adaptor-related protein complex 5, mu 1 subunit -1.30892
RAB2B RAB2B, member RAS oncogene family -1.30674
MTMR10 myotubularin related protein 10 -1.30661
HOPX HOP homeobox -1.30655
SLC48A1 solute carrier family 48 (heme transporter), member 1 -1.30596
SERINC5 serine incorporator 5 -1.29996
RABGAP1 RAB GTPase activating protein 1 -1.29872
ACBD5 acyl-CoA binding domain containing 5 -1.29574
NAT10 N-acetyltransferase 10 (GCN5-related) -1.29554
DEXI Dexi homolog (mouse) -1.29496
BTK Bruton agammaglobulinemia tyrosine kinase -1.29441
CPSF3 cleavage and polyadenylation specific factor 3, 73kDa -1.29439
FOXJ2 forkhead box J2 -1.29369
SARNP SAP domain containing ribonucleoprotein -1.29076
ZNF281 zinc finger protein 281 -1.28953
TADA3 transcriptional adaptor 3 -1.28882
VPS16 vacuolar protein sorting 16 homolog (S. cerevisiae) -1.28806
MTHFD1 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 1, methenyltetrahydrofolate cyclohydrolase, formyltetrahydrofolate synthetase -1.28777
NFIX nuclear factor I/X (CCAAT-binding transcription factor) -1.28662
PIK3CA phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit alpha -1.28632
CD9 CD9 molecule -1.28549
FARP2 FERM, RhoGEF and pleckstrin domain protein 2 -1.27982
ACBD3 acyl-CoA binding domain containing 3 -1.27924
NUDT18 nudix (nucleoside diphosphate linked moiety X)-type motif 18 -1.27867
UGP2 UDP-glucose pyrophosphorylase 2 -1.27805
SPICE1 spindle and centriole associated protein 1 -1.27799
CLYBL citrate lyase beta like -1.27609
RSF1 remodeling and spacing factor 1 -1.276
TRUB2 TruB pseudouridine (psi) synthase family member 2 -1.27546
FUOM fucose mutarotase -1.27442
SHOC2 soc-2 suppressor of clear homolog (C. elegans) -1.27175
KRIT1 KRIT1, ankyrin repeat containing -1.27123
TAPT1 transmembrane anterior posterior transformation 1 -1.2709
LSS lanosterol synthase (2,3-oxidosqualene-lanosterol cyclase) -1.26996
FOXN2 forkhead box N2 -1.26829
YBEY ybeY metallopeptidase (putative) -1.26376
CCDC174 coiled-coil domain containing 174 -1.26191
TMBIM1 transmembrane BAX inhibitor motif containing 1 -1.26108
SERTAD2 SERTA domain containing 2 -1.25869
CSNK1A1 casein kinase 1, alpha 1 -1.25843
NDUFA9 NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 9, 39kDa -1.2581
ENDOG endonuclease G -1.25762
MLH1 mutL homolog 1 -1.25666
LRRC8B leucine rich repeat containing 8 family, member B -1.25539
OLFML1 olfactomedin-like 1 -1.25467
GOLPH3L golgi phosphoprotein 3-like -1.24996
GLTP glycolipid transfer protein -1.24754
TXNL1 thioredoxin-like 1 -1.24419
RAB14 RAB14, member RAS oncogene family -1.24347
CCDC77 coiled-coil domain containing 77 -1.23934
LLGL1 lethal giant larvae homolog 1 (Drosophila) -1.23519
BCS1L BC1 (ubiquinol-cytochrome c reductase) synthesis-like -1.23182
FEM1A fem-1 homolog a (C. elegans) -1.23136
UTP6 UTP6, small subunit (SSU) processome component, homolog (yeast) -1.23023
ARL2BP ADP-ribosylation factor-like 2 binding protein -1.22986
RFWD2 ring finger and WD repeat domain 2, E3 ubiquitin protein ligase -1.22607
PSME4 proteasome (prosome, macropain) activator subunit 4 -1.22479
PDP2 pyruvate dehyrogenase phosphatase catalytic subunit 2 -1.22372
ALDH4A1 aldehyde dehydrogenase 4 family, member A1 -1.21932
THOP1 thimet oligopeptidase 1 -1.21823
GEMIN6 gem (nuclear organelle) associated protein 6 -1.21597
PGRMC2 progesterone receptor membrane component 2 -1.21388
PIP5K1A phosphatidylinositol-4-phosphate 5-kinase, type I, alpha -1.21378
KIAA0430 KIAA0430 -1.21349
SRSF4 serine/arginine-rich splicing factor 4 -1.21245
METRN meteorin, glial cell differentiation regulator -1.20807
VHL von Hippel-Lindau tumor suppressor, E3 ubiquitin protein ligase -1.20766
RB1 retinoblastoma 1 -1.2067
CDK2 cyclin-dependent kinase 2 -1.20613
RDH11 retinol dehydrogenase 11 (all-trans/9-cis/11-cis) -1.20484
ZBED3 zinc finger, BED-type containing 3 -1.20343
ZNF692 zinc finger protein 692 -1.20326
PDHA1 pyruvate dehydrogenase (lipoamide) alpha 1 -1.20065
DHX9 DEAH (Asp-Glu-Ala-His) box helicase 9 -1.19914
RNF180 ring finger protein 180 -1.19726
ILF2 interleukin enhancer binding factor 2 -1.19672
PGBD5 piggyBac transposable element derived 5 -1.1964
PMEL premelanosome protein -1.19633
TCIRG1 T-cell, immune regulator 1, ATPase, H+ transporting, lysosomal V0 subunit A3 -1.19614
SUV420H2 suppressor of variegation 4-20 homolog 2 (Drosophila) -1.19464
PPP1R7 protein phosphatase 1, regulatory subunit 7 -1.19109
ZBTB43 zinc finger and BTB domain containing 43 -1.18309
ALG8 ALG8, alpha-1,3-glucosyltransferase -1.182
MYRIP myosin VIIA and Rab interacting protein -1.18151
MRPS27 mitochondrial ribosomal protein S27 -1.17846
Funding