| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in A-427 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_A-427 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.11435 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0735807 |
| AREG | amphiregulin | 0.0701598 |
| CCNL1 | cyclin L1 | 0.051665 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0512799 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.048454 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0436542 |
| CCN2 | cellular communication network factor 2 | 0.0421259 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0418189 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.040932 |
| PCBP2 | poly(rC) binding protein 2 | 0.0408026 |
| CPOX | coproporphyrinogen oxidase | 0.0362399 |
| KIF5B | kinesin family member 5B | 0.0344375 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0339546 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0336126 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0335009 |
| ECT2 | epithelial cell transforming 2 | 0.0334714 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0327943 |
| YBX1 | Y box binding protein 1 | 0.0311793 |
| PNN | pinin, desmosome associated protein | 0.0310822 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0299057 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.0297511 |
| ANXA1 | annexin A1 | 0.0297319 |
| PSMD2 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 2 | 0.0295253 |
| CEP192 | centrosomal protein 192kDa | 0.0292929 |
| MED13L | mediator complex subunit 13-like | 0.0282276 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0281849 |
| RPL3 | ribosomal protein L3 | 0.0275599 |
| YBX3 | Y box binding protein 3 | 0.0269563 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0267007 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0266399 |
| CKAP5 | cytoskeleton associated protein 5 | 0.0265343 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0251593 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0247139 |
| TPR | translocated promoter region, nuclear basket protein | 0.0246532 |
| ZNF292 | zinc finger protein 292 | 0.0243675 |
| MLLT10 | myeloid/lymphoid or mixed-lineage leukemia (trithorax homolog, Drosophila); translocated to, 10 | 0.0241425 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0241136 |
| EDN1 | endothelin 1 | 0.0241073 |
| CALR | calreticulin | 0.0241012 |
| MGAT4C | MGAT4 family, member C | 0.0237623 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0229472 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.022325 |
| THOC1 | THO complex 1 | 0.0215943 |
| EPHA6 | EPH receptor A6 | 0.0214444 |
| SF3B2 | splicing factor 3b, subunit 2, 145kDa | 0.0213902 |
| SBNO1 | strawberry notch homolog 1 (Drosophila) | 0.021024 |
| KLHL24 | kelch-like family member 24 | 0.0207729 |
| HNRNPUL2 | heterogeneous nuclear ribonucleoprotein U-like 2 | 0.0205166 |
| GASK1B | golgi associated kinase 1B | 0.0202822 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0201346 |
| CRISPLD1 | cysteine-rich secretory protein LCCL domain containing 1 | 0.0201225 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0201094 |
| RNF145 | ring finger protein 145 | 0.0200547 |
| PCM1 | pericentriolar material 1 | 0.019979 |
| CHD1 | chromodomain helicase DNA binding protein 1 | 0.0199404 |
| RBM25 | RNA binding motif protein 25 | 0.019695 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0196897 |
| NCOR1 | nuclear receptor corepressor 1 | 0.0196832 |
| POLR2B | polymerase (RNA) II (DNA directed) polypeptide B, 140kDa | 0.0190003 |
| CASC3 | cancer susceptibility candidate 3 | 0.0189335 |
| SPAG5 | sperm associated antigen 5 | 0.0188468 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0187679 |
| NOLC1 | nucleolar and coiled-body phosphoprotein 1 | 0.0186096 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0183996 |
| CEP250 | centrosomal protein 250kDa | 0.0179859 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0178823 |
| CEP70 | centrosomal protein 70kDa | 0.0175647 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.017537 |
| ARHGAP12 | Rho GTPase activating protein 12 | 0.0175041 |
| MATR3 | matrin 3 | 0.017405 |
| RBM27 | RNA binding motif protein 27 | 0.0172102 |
| AGPAT1 | 1-acylglycerol-3-phosphate O-acyltransferase 1 | 0.0172042 |
| BRWD3 | bromodomain and WD repeat domain containing 3 | 0.0171553 |
| ARRDC3 | arrestin domain containing 3 | 0.017133 |
| FUS | FUS RNA binding protein | 0.0169757 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0169007 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0168941 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0166537 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0166372 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0165819 |
| WDR43 | WD repeat domain 43 | 0.0165376 |
| GABARAPL1 | GABA(A) receptor-associated protein like 1 | 0.0165025 |
| CLDND1 | claudin domain containing 1 | 0.0164022 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0164019 |
| EGLN1 | egl-9 family hypoxia-inducible factor 1 | 0.0163845 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0162684 |
| ENAH | enabled homolog (Drosophila) | 0.0161614 |
| PER1 | period circadian clock 1 | 0.0161539 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0161304 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0160729 |
| NEK7 | NIMA-related kinase 7 | 0.0160253 |
| QKI | QKI, KH domain containing, RNA binding | 0.0159615 |
| AXIN2 | axin 2 | 0.0158943 |
| DDB1 | damage-specific DNA binding protein 1, 127kDa | 0.0157938 |
| MKI67 | marker of proliferation Ki-67 | 0.0157241 |
| RPN1 | ribophorin I | 0.0156353 |
| OXR1 | oxidation resistance 1 | 0.0156256 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0155869 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0154353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.272936 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.244862 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.224129 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.168248 |
| HMGA2 | high mobility group AT-hook 2 | -0.159238 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.122771 |
| MMP12 | matrix metallopeptidase 12 | -0.0964731 |
| EHBP1 | EH domain binding protein 1 | -0.0847274 |
| SERPINB2 | serpin peptidase inhibitor, clade B (ovalbumin), member 2 | -0.0760819 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.066608 |
| BCHE | butyrylcholinesterase | -0.0645021 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0632572 |
| JMJD1C | jumonji domain containing 1C | -0.0587654 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0583223 |
| ZNF804A | zinc finger protein 804A | -0.0578438 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0566412 |
| CANX | calnexin | -0.0565052 |
| RPS8 | ribosomal protein S8 | -0.0562078 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0562002 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0551535 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0541181 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0532418 |
| RPS6 | ribosomal protein S6 | -0.0508535 |
| PCDH7 | protocadherin 7 | -0.0505553 |
| TMSB10 | thymosin beta 10 | -0.0505229 |
| YAP1 | Yes-associated protein 1 | -0.0501252 |
| ASPH | aspartate beta-hydroxylase | -0.0490239 |
| NHSL1 | NHS-like 1 | -0.0473638 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0457296 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | -0.0453348 |
| INTS6 | integrator complex subunit 6 | -0.0447801 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0440645 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0440554 |
| RASAL2 | RAS protein activator like 2 | -0.0437897 |
| RPS23 | ribosomal protein S23 | -0.0436678 |
| RPS13 | ribosomal protein S13 | -0.0427175 |
| CUX1 | cut-like homeobox 1 | -0.0423287 |
| MSRB3 | methionine sulfoxide reductase B3 | -0.0417235 |
| TUBA1B | tubulin, alpha 1b | -0.0416975 |
| RPS27A | ribosomal protein S27a | -0.0410684 |
| NLGN1 | neuroligin 1 | -0.0398928 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0396114 |
| LRRTM4 | leucine rich repeat transmembrane neuronal 4 | -0.0395929 |
| MTAP | methylthioadenosine phosphorylase | -0.0388567 |
| ADIPOR2 | adiponectin receptor 2 | -0.0378785 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0377664 |
| RPL34 | ribosomal protein L34 | -0.0377437 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0376186 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0373631 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0369381 |
| MAP1B | microtubule-associated protein 1B | -0.0361656 |
| BIRC3 | baculoviral IAP repeat containing 3 | -0.0361603 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0360395 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0357866 |
| EGR1 | early growth response 1 | -0.0351996 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.0351871 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0348014 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0340546 |
| ALDH1A1 | aldehyde dehydrogenase 1 family, member A1 | -0.0337158 |
| RPLP1 | ribosomal protein, large, P1 | -0.0333292 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.033183 |
| ENO1 | enolase 1, (alpha) | -0.0331617 |
| TMEM123 | transmembrane protein 123 | -0.0329253 |
| RAB10 | RAB10, member RAS oncogene family | -0.0324064 |
| RPLP0 | ribosomal protein, large, P0 | -0.0323994 |
| S100A6 | S100 calcium binding protein A6 | -0.032355 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.0320178 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0316501 |
| S100A10 | S100 calcium binding protein A10 | -0.0315447 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0315135 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0314488 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0307526 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0304349 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0303069 |
| RPL37A | ribosomal protein L37a | -0.0302741 |
| CLDN1 | claudin 1 | -0.0301827 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0299585 |
| LRRC23 | leucine rich repeat containing 23 | -0.0297362 |
| RPS12 | ribosomal protein S12 | -0.029256 |
| RPL37 | ribosomal protein L37 | -0.0290967 |
| VMP1 | vacuole membrane protein 1 | -0.0289052 |
| CUBN | cubilin (intrinsic factor-cobalamin receptor) | -0.0283205 |
| HMGA1 | high mobility group AT-hook 1 | -0.0282773 |
| EIF4G3 | eukaryotic translation initiation factor 4 gamma, 3 | -0.02825 |
| RPLP2 | ribosomal protein, large, P2 | -0.0282427 |
| RPL35A | ribosomal protein L35a | -0.0279611 |
| RPS29 | ribosomal protein S29 | -0.0273212 |
| ACTG1 | actin gamma 1 | -0.0272538 |
| TPM4 | tropomyosin 4 | -0.0271785 |
| VTI1A | vesicle transport through interaction with t-SNAREs 1A | -0.0270767 |
| RPL10A | ribosomal protein L10a | -0.0270568 |
| BPTF | bromodomain PHD finger transcription factor | -0.0269029 |
| RPS27 | ribosomal protein S27 | -0.0264779 |
| FGFR1 | fibroblast growth factor receptor 1 | -0.0260137 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0257349 |
| RPS24 | ribosomal protein S24 | -0.0256975 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0254223 |
| RPS14 | ribosomal protein S14 | -0.0253609 |
| GCG | glucagon | -0.0251638 |
| CLIP1 | CAP-GLY domain containing linker protein 1 | -0.0250552 |
