| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.109188 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | 0.0866012 |
| LPIN1 | lipin 1 | 0.0865501 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0753475 |
| ACTG1 | actin gamma 1 | 0.0682708 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0636754 |
| FMN1 | formin 1 | 0.0575997 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0550698 |
| DSCAM | Down syndrome cell adhesion molecule | 0.05458 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0527735 |
| RNF213 | ring finger protein 213 | 0.0480764 |
| MYCN | v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog | 0.0475602 |
| RPL4 | ribosomal protein L4 | 0.047362 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0467716 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0461661 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0443936 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0443384 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0442774 |
| VEGFA | vascular endothelial growth factor A | 0.0441178 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0440642 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0439192 |
| TRIB2 | tribbles pseudokinase 2 | 0.0432843 |
| TANC1 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 1 | 0.0419022 |
| MMP2 | matrix metallopeptidase 2 | 0.0417033 |
| SMAD3 | SMAD family member 3 | 0.0411288 |
| TPST1 | tyrosylprotein sulfotransferase 1 | 0.0395695 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0394414 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0387901 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0376361 |
| APP | amyloid beta (A4) precursor protein | 0.0369348 |
| AHNAK | AHNAK nucleoprotein | 0.0355862 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.035516 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0343591 |
| TLE4 | transducin-like enhancer of split 4 | 0.0339191 |
| RPL7A | ribosomal protein L7a | 0.0338772 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0332948 |
| PTMA | prothymosin, alpha | 0.03271 |
| AOPEP | aminopeptidase O (putative) | 0.0326365 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0324552 |
| VGF | VGF nerve growth factor inducible | 0.0320447 |
| MEIS2 | Meis homeobox 2 | 0.0317478 |
| CALR | calreticulin | 0.0317407 |
| PRPF8 | pre-mRNA processing factor 8 | 0.030778 |
| CLTC | clathrin, heavy chain (Hc) | 0.0301868 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0300892 |
| GAB2 | GRB2-associated binding protein 2 | 0.0300716 |
| TENT5A | terminal nucleotidyltransferase 5A | 0.0295985 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0292349 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.029201 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0291406 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.028981 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0287483 |
| KLHL13 | kelch-like family member 13 | 0.0284125 |
| SPAG9 | sperm associated antigen 9 | 0.0283201 |
| SEPTIN9 | septin 9 | 0.0278139 |
| USP36 | ubiquitin specific peptidase 36 | 0.0275975 |
| TBX2 | T-box 2 | 0.0273885 |
| COL3A1 | collagen, type III, alpha 1 | 0.0271881 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0270585 |
| FDXR | ferredoxin reductase | 0.0265916 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0264971 |
| DDX42 | DEAD (Asp-Glu-Ala-Asp) box helicase 42 | 0.0262114 |
| RPL3 | ribosomal protein L3 | 0.0262108 |
| SIK2 | salt-inducible kinase 2 | 0.0258595 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0252257 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0249348 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0247845 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0242098 |
| ARID5B | AT rich interactive domain 5B (MRF1-like) | 0.024092 |
| RPL23 | ribosomal protein L23 | 0.0240459 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0235748 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0235171 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0232841 |
| PIP5K1A | phosphatidylinositol-4-phosphate 5-kinase, type I, alpha | 0.0231023 |
| SET | SET nuclear proto-oncogene | 0.0226886 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0223884 |
| GPCPD1 | glycerophosphocholine phosphodiesterase GDE1 homolog (S. cerevisiae) | 0.0222947 |
| B2M | beta-2-microglobulin | 0.0214682 |
| PCBP3 | poly(rC) binding protein 3 | 0.020881 |
| KHDC4 | KH domain containing 4, pre-mRNA splicing factor | 0.0207075 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.020587 |
| SSBP3 | single stranded DNA binding protein 3 | 0.0204737 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0204675 |
| CTSB | cathepsin B | 0.020015 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0198488 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | 0.0198361 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0197963 |
| PRRC2B | proline-rich coiled-coil 2B | 0.0197366 |
| AMOTL1 | angiomotin like 1 | 0.0196676 |
| GLCCI1 | glucocorticoid induced 1 | 0.0194311 |
| ADAMTS9 | ADAM metallopeptidase with thrombospondin type 1 motif, 9 | 0.0191042 |
| DLG5 | discs, large homolog 5 (Drosophila) | 0.0187562 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0186415 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0186267 |
| CASC3 | cancer susceptibility candidate 3 | 0.018583 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0185623 |
| TPR | translocated promoter region, nuclear basket protein | 0.0185364 |
| SH3PXD2B | SH3 and PX domains 2B | 0.0185116 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0184166 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0183294 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.22486 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.146553 |
| NRG1 | neuregulin 1 | -0.0940625 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0667698 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0608939 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0550316 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0527091 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.0472384 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0459493 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.042556 |
| NDRG1 | N-myc downstream regulated 1 | -0.0421252 |
| LIMCH1 | LIM and calponin homology domains 1 | -0.0420773 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0386879 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0385211 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.038057 |
| BCAT1 | branched chain amino-acid transaminase 1, cytosolic | -0.035434 |
| BPTF | bromodomain PHD finger transcription factor | -0.0348771 |
| GDF15 | growth differentiation factor 15 | -0.0341686 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0340572 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0331451 |
| CPED1 | cadherin-like and PC-esterase domain containing 1 | -0.0329685 |
| RBMS3 | RNA binding motif, single stranded interacting protein 3 | -0.0324622 |
| SLITRK6 | SLIT and NTRK-like family, member 6 | -0.0316832 |
| EXOC4 | exocyst complex component 4 | -0.031413 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0312051 |
| CADM2 | cell adhesion molecule 2 | -0.0309488 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0299484 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0277614 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0275866 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0275255 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | -0.0260644 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.025889 |
| CENPF | centromere protein F, 350/400kDa | -0.0251272 |
| B3GALT1 | UDP-Gal:betaGlcNAc beta 1,3-galactosyltransferase, polypeptide 1 | -0.0248866 |
| ZNF292 | zinc finger protein 292 | -0.0241532 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.02387 |
| DCAF7 | DDB1 and CUL4 associated factor 7 | -0.0234666 |
| CACNA2D1 | calcium channel, voltage-dependent, alpha 2/delta subunit 1 | -0.0233114 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.023081 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0229573 |
| STARD4 | StAR-related lipid transfer (START) domain containing 4 | -0.0229527 |
| SYT1 | synaptotagmin I | -0.0229284 |
| CDH13 | cadherin 13 | -0.0229093 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | -0.0228971 |
| RTN4 | reticulon 4 | -0.0228489 |
| VIM | vimentin | -0.0224339 |
| STXBP5 | syntaxin binding protein 5 (tomosyn) | -0.0221965 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0221304 |
| DLC1 | DLC1 Rho GTPase activating protein | -0.0214753 |
| DTNA | dystrobrevin, alpha | -0.021468 |
| DIAPH2 | diaphanous-related formin 2 | -0.0213374 |
| RPL34 | ribosomal protein L34 | -0.0211935 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0210949 |
| COL4A5 | collagen, type IV, alpha 5 | -0.0210107 |
| PCDH9 | protocadherin 9 | -0.0209521 |
| STC1 | stanniocalcin 1 | -0.0206351 |
| MEF2A | myocyte enhancer factor 2A | -0.0204661 |
| FAM162A | family with sequence similarity 162, member A | -0.020213 |
| C1ORF21 | chromosome 1 open reading frame 21 | -0.0199016 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | -0.0198329 |
| HMGA1 | high mobility group AT-hook 1 | -0.0198028 |
| SMC4 | structural maintenance of chromosomes 4 | -0.0197483 |
| BAZ2B | bromodomain adjacent to zinc finger domain, 2B | -0.0196211 |
| ZCCHC7 | zinc finger, CCHC domain containing 7 | -0.0192864 |
| DPH6 | diphthamine biosynthesis 6 | -0.0192707 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.0191056 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.019084 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0189259 |
| ENO1 | enolase 1, (alpha) | -0.0188833 |
| PFN1 | profilin 1 | -0.0187978 |
| ANKIB1 | ankyrin repeat and IBR domain containing 1 | -0.0187333 |
| KCNIP4 | Kv channel interacting protein 4 | -0.0186414 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0185869 |
| HMGA2 | high mobility group AT-hook 2 | -0.0184896 |
| USP34 | ubiquitin specific peptidase 34 | -0.0183967 |
| ZNF609 | zinc finger protein 609 | -0.0181946 |
| LRRC7 | leucine rich repeat containing 7 | -0.0178906 |
| SCFD1 | sec1 family domain containing 1 | -0.0176864 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0172411 |
| PRKCA | protein kinase C, alpha | -0.0171493 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | -0.0171313 |
| SEPTIN7 | septin 7 | -0.017057 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0168756 |
| SLIT2 | slit homolog 2 (Drosophila) | -0.0168408 |
| NFIX | nuclear factor I/X (CCAAT-binding transcription factor) | -0.0167863 |
| ATF4 | activating transcription factor 4 | -0.0167719 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0166988 |
| PCDH7 | protocadherin 7 | -0.0166785 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0166447 |
| MBTD1 | mbt domain containing 1 | -0.0165463 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0161632 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | -0.0161192 |
| SRP54 | signal recognition particle 54kDa | -0.01608 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0160243 |
| SKIC3 | SKI3 subunit of superkiller complex | -0.015922 |
| EPHA3 | EPH receptor A3 | -0.0159183 |
| TOX | thymocyte selection-associated high mobility group box | -0.0158927 |
| TXNRD1 | thioredoxin reductase 1 | -0.0158905 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0158503 |
| VCL | vinculin | -0.0157665 |
