| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.11842 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0863064 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0806095 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0666626 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0663923 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | 0.0661838 |
| TXNIP | thioredoxin interacting protein | 0.0656097 |
| B2M | beta-2-microglobulin | 0.0641014 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | 0.0629127 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0616127 |
| RNF149 | ring finger protein 149 | 0.0610279 |
| NDRG1 | N-myc downstream regulated 1 | 0.0566025 |
| CALR | calreticulin | 0.0560179 |
| TSC22D1 | TSC22 domain family, member 1 | 0.0552351 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0474458 |
| ATP2C2 | ATPase, Ca++ transporting, type 2C, member 2 | 0.0448284 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0444179 |
| RHOBTB3 | Rho-related BTB domain containing 3 | 0.0443523 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0443092 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0439223 |
| PTBP3 | polypyrimidine tract binding protein 3 | 0.0423589 |
| COPA | coatomer protein complex, subunit alpha | 0.0415795 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | 0.0392927 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | 0.0390387 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0389314 |
| ACBD3 | acyl-CoA binding domain containing 3 | 0.0372494 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0367832 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0363491 |
| PCK1 | phosphoenolpyruvate carboxykinase 1 (soluble) | 0.0360114 |
| ZMYND8 | zinc finger, MYND-type containing 8 | 0.0359325 |
| IFNGR1 | interferon gamma receptor 1 | 0.0356665 |
| STK24 | serine/threonine kinase 24 | 0.035415 |
| GOLGA2 | golgin A2 | 0.035309 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0349388 |
| TMPRSS4 | transmembrane protease, serine 4 | 0.0348176 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.034334 |
| HELZ | helicase with zinc finger | 0.0342125 |
| DHRS3 | dehydrogenase/reductase (SDR family) member 3 | 0.0341018 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0334368 |
| RNF43 | ring finger protein 43 | 0.0333584 |
| FNIP1 | folliculin interacting protein 1 | 0.0332628 |
| PTEN | phosphatase and tensin homolog | 0.0328728 |
| HLA-B | major histocompatibility complex, class I, B | 0.0328213 |
| CANX | calnexin | 0.0323953 |
| ZMYM2 | zinc finger, MYM-type 2 | 0.0319995 |
| UBC | ubiquitin C | 0.0316858 |
| WDR45B | WD repeat domain 45B | 0.0310404 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0290369 |
| VEGFA | vascular endothelial growth factor A | 0.0289767 |
| EHF | ets homologous factor | 0.0284807 |
| TMEM51 | transmembrane protein 51 | 0.0284603 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0282479 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | 0.0279048 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.0277809 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0274572 |
| SEC24D | SEC24 family member D | 0.0267046 |
| CPEB4 | cytoplasmic polyadenylation element binding protein 4 | 0.0265179 |
| TTC3 | tetratricopeptide repeat domain 3 | 0.0264221 |
| SCNN1A | sodium channel, non voltage gated 1 alpha subunit | 0.0262771 |
| PPP1CB | protein phosphatase 1, catalytic subunit, beta isozyme | 0.0262139 |
| OGA | O-GlcNAcase | 0.0260942 |
| SUCO | SUN domain containing ossification factor | 0.025944 |
| NRIP1 | nuclear receptor interacting protein 1 | 0.0257006 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0254763 |
| PACSIN2 | protein kinase C and casein kinase substrate in neurons 2 | 0.0253311 |
| CREB3L2 | cAMP responsive element binding protein 3-like 2 | 0.0250683 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0247512 |
| MLPH | melanophilin | 0.0246912 |
| DNM2 | dynamin 2 | 0.02469 |
| FNDC3A | fibronectin type III domain containing 3A | 0.02466 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0245116 |
| COPG1 | coatomer protein complex, subunit gamma 1 | 0.0244648 |
| SFTPA2 | surfactant protein A2 | 0.0243349 |
| COG6 | component of oligomeric golgi complex 6 | 0.0243306 |
| USP3 | ubiquitin specific peptidase 3 | 0.0243203 |
| TMED2 | transmembrane emp24 domain trafficking protein 2 | 0.0242625 |
| MKI67 | marker of proliferation Ki-67 | 0.0240044 |
| ABHD2 | abhydrolase domain containing 2 | 0.0240007 |
| NEDD9 | neural precursor cell expressed, developmentally down-regulated 9 | 0.0238331 |
| PDIA4 | protein disulfide isomerase family A, member 4 | 0.0238053 |
| GOLGA4 | golgin A4 | 0.0237937 |
| KLHL24 | kelch-like family member 24 | 0.0234834 |
| OARD1 | O-acyl-ADP-ribose deacylase 1 | 0.0232821 |
| ZNF148 | zinc finger protein 148 | 0.0232813 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0230956 |
| GOLGB1 | golgin B1 | 0.0230473 |
| PHF3 | PHD finger protein 3 | 0.0228411 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | 0.0227638 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0227589 |
| RAB1A | RAB1A, member RAS oncogene family | 0.0225402 |
| IL20RA | interleukin 20 receptor, alpha | 0.0224832 |
| CLTC | clathrin, heavy chain (Hc) | 0.0224321 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0223634 |
| TPR | translocated promoter region, nuclear basket protein | 0.0222699 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | 0.0222582 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0222055 |
| MON2 | MON2 homolog (S. cerevisiae) | 0.0219966 |
| NCOR2 | nuclear receptor corepressor 2 | 0.0219357 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | 0.021909 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0218418 |
| Symbol | Name | Standardized Value |
|---|---|---|
| INTS6 | integrator complex subunit 6 | -0.180851 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.143596 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.139635 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | -0.13457 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.131187 |
| RNF213 | ring finger protein 213 | -0.124782 |
| SP100 | SP100 nuclear antigen | -0.123126 |
| RIGI | RNA sensor RIG-I | -0.121657 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | -0.117036 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.110513 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | -0.103982 |
| PLSCR2 | phospholipid scramblase 2 | -0.0955241 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0919385 |
| NPSR1 | neuropeptide S receptor 1 | -0.0900334 |
| ANXA2 | annexin A2 | -0.0875044 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0850914 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0829776 |
| MX2 | MX dynamin-like GTPase 2 | -0.0810035 |
| MX1 | MX dynamin-like GTPase 1 | -0.0804867 |
| VCL | vinculin | -0.0788616 |
| XAF1 | XIAP associated factor 1 | -0.0779561 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | -0.0768077 |
| CHST11 | carbohydrate (chondroitin 4) sulfotransferase 11 | -0.0736553 |
| RSAD2 | radical S-adenosyl methionine domain containing 2 | -0.0708638 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0665218 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0657193 |
| PLSCR1 | phospholipid scramblase 1 | -0.0639474 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0625608 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0622551 |
| CATSPERB | catsper channel auxiliary subunit beta | -0.0593962 |
| LMO7 | LIM domain 7 | -0.058553 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0561196 |
| EXT1 | exostosin glycosyltransferase 1 | -0.055132 |
| SQSTM1 | sequestosome 1 | -0.05508 |
| EFNB2 | ephrin-B2 | -0.0534465 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0534155 |
| AREG | amphiregulin | -0.0533 |
| LYZ | lysozyme | -0.0530281 |
| SYNE2 | spectrin repeat containing, nuclear envelope 2 | -0.0519069 |
| OAS2 | 2'-5'-oligoadenylate synthetase 2, 69/71kDa | -0.0516677 |
| RABGAP1L | RAB GTPase activating protein 1-like | -0.0510824 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0505209 |
| PERP | PERP, TP53 apoptosis effector | -0.0504718 |
| PRKCA | protein kinase C, alpha | -0.0497128 |
| LAMA4 | laminin, alpha 4 | -0.0483422 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | -0.0480497 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0480055 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0472413 |
| LCN2 | lipocalin 2 | -0.0467744 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0461274 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0456649 |
| EGR1 | early growth response 1 | -0.0453301 |
| NABP1 | nucleic acid binding protein 1 | -0.0449021 |
| POF1B | premature ovarian failure, 1B | -0.0433041 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0432567 |
| ASPH | aspartate beta-hydroxylase | -0.0431777 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0426098 |
| ARHGEF38 | Rho guanine nucleotide exchange factor (GEF) 38 | -0.0425524 |
| NAALADL2 | N-acetylated alpha-linked acidic dipeptidase-like 2 | -0.0417226 |
| TM4SF19 | transmembrane 4 L six family member 19 | -0.0412666 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0401366 |
| SAMD9 | sterile alpha motif domain containing 9 | -0.039322 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0382035 |
| RAD51B | RAD51 paralog B | -0.0377718 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0373915 |
| FHIT | fragile histidine triad | -0.0369469 |
| FBXO39 | F-box protein 39 | -0.0362833 |
| ACTG1 | actin gamma 1 | -0.0353089 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0352797 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0352175 |
| CEMIP | cell migration inducing protein, hyaluronan binding | -0.0349294 |
| ATP11A | ATPase, class VI, type 11A | -0.034925 |
| TJP1 | tight junction protein 1 | -0.0341177 |
| PMP22 | peripheral myelin protein 22 | -0.0334762 |
| MSI2 | musashi RNA-binding protein 2 | -0.03339 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0333321 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0330709 |
| CUX1 | cut-like homeobox 1 | -0.0329975 |
| EPHB2 | EPH receptor B2 | -0.0323218 |
| CSTPP1 | centriolar satellite-associated tubulin polyglutamylase complex regulator 1 | -0.0322818 |
| UBAP2 | ubiquitin associated protein 2 | -0.0321786 |
| VMP1 | vacuole membrane protein 1 | -0.0319444 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0314097 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0311447 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0306414 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0305958 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0301268 |
| SSH2 | slingshot protein phosphatase 2 | -0.0299758 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | -0.0298425 |
| INPP4B | inositol polyphosphate-4-phosphatase, type II, 105kDa | -0.0294918 |
| PARD3 | par-3 family cell polarity regulator | -0.0293384 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | -0.0285231 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | -0.0280362 |
| SAMD12 | sterile alpha motif domain containing 12 | -0.0276896 |
| IGF1R | insulin-like growth factor 1 receptor | -0.027611 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0273684 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | -0.0273194 |
| ETV6 | ets variant 6 | -0.0272864 |
| ALCAM | activated leukocyte cell adhesion molecule | -0.0270701 |
| EPB41L1 | erythrocyte membrane protein band 4.1-like 1 | -0.0270351 |
