| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in MIA PaCa-2 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_MIA PaCa-2 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| EEF2 | eukaryotic translation elongation factor 2 | 0.222336 |
| TMSB4X | thymosin beta 4, X-linked | 0.213934 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.182483 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.11781 |
| EZR | ezrin | 0.0819425 |
| CAPRIN2 | caprin family member 2 | 0.0766477 |
| CALR | calreticulin | 0.0721818 |
| ACTG1 | actin gamma 1 | 0.0708889 |
| LOXL2 | lysyl oxidase-like 2 | 0.0702227 |
| APP | amyloid beta (A4) precursor protein | 0.0697346 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0667898 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0648576 |
| FMNL2 | formin-like 2 | 0.0646111 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0645978 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0583858 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0539064 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0527723 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.0516335 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0513454 |
| FLNB | filamin B, beta | 0.0513114 |
| JUN | jun proto-oncogene | 0.050189 |
| SPAG9 | sperm associated antigen 9 | 0.0499259 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.049404 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0473752 |
| PODXL | podocalyxin-like | 0.046274 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0457005 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.044692 |
| RPL3 | ribosomal protein L3 | 0.0426235 |
| HSPA8 | heat shock 70kDa protein 8 | 0.040818 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0405686 |
| RAI1 | retinoic acid induced 1 | 0.0387151 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0381383 |
| PTMA | prothymosin, alpha | 0.0380511 |
| SMAD3 | SMAD family member 3 | 0.0380219 |
| POTEF | POTE ankyrin domain family, member F | 0.0371889 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0365874 |
| MYOF | myoferlin | 0.0364523 |
| NAV2 | neuron navigator 2 | 0.0364348 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0363292 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0362797 |
| MCL1 | myeloid cell leukemia 1 | 0.0353657 |
| ASAP1 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 1 | 0.0353232 |
| CLIP2 | CAP-GLY domain containing linker protein 2 | 0.035298 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0350507 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.0350002 |
| YEATS2 | YEATS domain containing 2 | 0.0347788 |
| VEGFA | vascular endothelial growth factor A | 0.0336399 |
| RPN1 | ribophorin I | 0.0336301 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0331623 |
| TXNRD1 | thioredoxin reductase 1 | 0.0331077 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0328302 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0328125 |
| SLC4A7 | solute carrier family 4, sodium bicarbonate cotransporter, member 7 | 0.0322101 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0319726 |
| SDC4 | syndecan 4 | 0.0315773 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0315101 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0314692 |
| CEP250 | centrosomal protein 250kDa | 0.0298345 |
| IGFBP6 | insulin-like growth factor binding protein 6 | 0.0296302 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0295945 |
| MKI67 | marker of proliferation Ki-67 | 0.0295567 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0294575 |
| DOCK11 | dedicator of cytokinesis 11 | 0.0289999 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0288608 |
| TPM3 | tropomyosin 3 | 0.0288597 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0285006 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0283919 |
| BRD2 | bromodomain containing 2 | 0.0283741 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.028324 |
| HELZ | helicase with zinc finger | 0.0280748 |
| PLEC | plectin | 0.0280645 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0279834 |
| RPL7A | ribosomal protein L7a | 0.0279519 |
| SFTPA2 | surfactant protein A2 | 0.027865 |
| ADM | adrenomedullin | 0.0276605 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0275439 |
| SERPINA3 | serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 3 | 0.0274104 |
| SET | SET nuclear proto-oncogene | 0.0269938 |
| PCDH1 | protocadherin 1 | 0.0267826 |
| ZNF160 | zinc finger protein 160 | 0.0267203 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0261845 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0261795 |
| CNBP | CCHC-type zinc finger, nucleic acid binding protein | 0.0261322 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0259489 |
| UPP1 | uridine phosphorylase 1 | 0.0257726 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0257148 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0257075 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0255879 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.025523 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0252637 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0251687 |
| ANXA1 | annexin A1 | 0.0249737 |
| BNIP3L | BCL2/adenovirus E1B 19kDa interacting protein 3-like | 0.0249324 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0249127 |
| HSPG2 | heparan sulfate proteoglycan 2 | 0.0244535 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0244424 |
| YWHAG | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, gamma | 0.0244371 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0243406 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0242541 |
| YBX1 | Y box binding protein 1 | 0.0242107 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.252574 |
| VIM | vimentin | -0.192651 |
| TP63 | tumor protein p63 | -0.0769152 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0757901 |
| RPL35A | ribosomal protein L35a | -0.0674934 |
| MT2A | metallothionein 2A | -0.064399 |
| RPS8 | ribosomal protein S8 | -0.0631483 |
| RPS6 | ribosomal protein S6 | -0.0603012 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0529603 |
| RPL34 | ribosomal protein L34 | -0.0513802 |
| CADM2 | cell adhesion molecule 2 | -0.0510515 |
| RPLP0 | ribosomal protein, large, P0 | -0.0504075 |
| RPLP2 | ribosomal protein, large, P2 | -0.0497053 |
| RPLP1 | ribosomal protein, large, P1 | -0.0487459 |
| RPS24 | ribosomal protein S24 | -0.0487369 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0475214 |
| TMSB10 | thymosin beta 10 | -0.0472619 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0458224 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0434094 |
| RPS19 | ribosomal protein S19 | -0.0415299 |
| RPS23 | ribosomal protein S23 | -0.0387965 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0382072 |
| RPS13 | ribosomal protein S13 | -0.0370018 |
| RPL31 | ribosomal protein L31 | -0.0350888 |
| MT1E | metallothionein 1E | -0.034726 |
| RPL37 | ribosomal protein L37 | -0.0345972 |
| RPL36A | ribosomal protein L36a | -0.0324586 |
| RPL26 | ribosomal protein L26 | -0.0324217 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0322975 |
| RPS12 | ribosomal protein S12 | -0.0322159 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0320162 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0318808 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.0308097 |
| CD44 | CD44 molecule (Indian blood group) | -0.029811 |
| S100A9 | S100 calcium binding protein A9 | -0.0293908 |
| RPS25 | ribosomal protein S25 | -0.0292485 |
| RPS27A | ribosomal protein S27a | -0.0285885 |
| GCLM | glutamate-cysteine ligase, modifier subunit | -0.0284834 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0284076 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.0279353 |
| RPL9 | ribosomal protein L9 | -0.0277387 |
| HMGB1 | high mobility group box 1 | -0.0276136 |
| RPL12 | ribosomal protein L12 | -0.0274129 |
| RPS21 | ribosomal protein S21 | -0.0273646 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0269034 |
| RPS27 | ribosomal protein S27 | -0.026762 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0266583 |
| RPS14 | ribosomal protein S14 | -0.026622 |
| RPS28 | ribosomal protein S28 | -0.0260522 |
| RPL27A | ribosomal protein L27a | -0.0258207 |
| MT1X | metallothionein 1X | -0.0257158 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0255899 |
| CANX | calnexin | -0.0255133 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0253382 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0251641 |
| RPL36 | ribosomal protein L36 | -0.0251613 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0249025 |
| RPL38 | ribosomal protein L38 | -0.0247448 |
| SRGN | serglycin | -0.0247063 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0246409 |
| RPS20 | ribosomal protein S20 | -0.0242975 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0241571 |
| RPS29 | ribosomal protein S29 | -0.0241221 |
| HMGA1 | high mobility group AT-hook 1 | -0.0239608 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0234407 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0234207 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0232233 |
| FTL | ferritin, light polypeptide | -0.0226995 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0222882 |
| RPS16 | ribosomal protein S16 | -0.0222599 |
| RPL10A | ribosomal protein L10a | -0.022245 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0222268 |
| DEK | DEK proto-oncogene | -0.0221936 |
| SP100 | SP100 nuclear antigen | -0.0220112 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0215593 |
| PLSCR1 | phospholipid scramblase 1 | -0.021507 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | -0.0210718 |
| CDK6 | cyclin-dependent kinase 6 | -0.0210263 |
| RPL35 | ribosomal protein L35 | -0.0209562 |
| S100A10 | S100 calcium binding protein A10 | -0.0209106 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0207401 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0205794 |
| PFN1 | profilin 1 | -0.0205764 |
| NOP58 | NOP58 ribonucleoprotein | -0.0205434 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0201141 |
| CFAP299 | cilia and flagella associated protein 299 | -0.0199158 |
| LRPPRC | leucine-rich pentatricopeptide repeat containing | -0.0198458 |
| RPL27 | ribosomal protein L27 | -0.0196701 |
| ZFR | zinc finger RNA binding protein | -0.0196598 |
| RPL32 | ribosomal protein L32 | -0.0195489 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0193681 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0192038 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0190937 |
| ZNF292 | zinc finger protein 292 | -0.0190013 |
| SEPTIN7 | septin 7 | -0.0188413 |
| FAF1 | Fas (TNFRSF6) associated factor 1 | -0.0187016 |
| DNAH14 | dynein, axonemal, heavy chain 14 | -0.0185022 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0184111 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0183946 |
| ZNF217 | zinc finger protein 217 | -0.0183733 |
