| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in NCI-H1573 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_NCI-H1573 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.363885 |
| MCL1 | myeloid cell leukemia 1 | 0.0993228 |
| LAMC2 | laminin, gamma 2 | 0.0928921 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.080406 |
| SMAD3 | SMAD family member 3 | 0.0659194 |
| CES1 | carboxylesterase 1 | 0.0655077 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0611585 |
| MKI67 | marker of proliferation Ki-67 | 0.0597274 |
| PLEC | plectin | 0.0588117 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0526798 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0503232 |
| EGR1 | early growth response 1 | 0.0470571 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0469223 |
| GSK3B | glycogen synthase kinase 3 beta | 0.0456998 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0454062 |
| CCNL1 | cyclin L1 | 0.0444782 |
| RNF213 | ring finger protein 213 | 0.0430499 |
| ACTG1 | actin gamma 1 | 0.0413011 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0402764 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0401885 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0397506 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | 0.039455 |
| SLC16A3 | solute carrier family 16 (monocarboxylate transporter), member 3 | 0.0380997 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0379556 |
| NR4A2 | nuclear receptor subfamily 4, group A, member 2 | 0.0356303 |
| SHANK2 | SH3 and multiple ankyrin repeat domains 2 | 0.0354083 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | 0.0347 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0344538 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | 0.0332034 |
| RPL3 | ribosomal protein L3 | 0.0330607 |
| FAM13A | family with sequence similarity 13, member A | 0.0324102 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.0312879 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0311498 |
| SLTM | SAFB-like, transcription modulator | 0.0307372 |
| CYP24A1 | cytochrome P450, family 24, subfamily A, polypeptide 1 | 0.0301967 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0300773 |
| AREG | amphiregulin | 0.0296319 |
| ANXA2 | annexin A2 | 0.0295985 |
| NR4A1 | nuclear receptor subfamily 4, group A, member 1 | 0.0295689 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.029208 |
| NPC1 | Niemann-Pick disease, type C1 | 0.0287855 |
| ARGLU1 | arginine and glutamate rich 1 | 0.0286796 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0286407 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0285824 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0279099 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0274215 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | 0.0273745 |
| CPE | carboxypeptidase E | 0.0257625 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.025717 |
| MSN | moesin | 0.0254953 |
| VEGFA | vascular endothelial growth factor A | 0.025428 |
| SDC4 | syndecan 4 | 0.025271 |
| MT2A | metallothionein 2A | 0.0251449 |
| EPAS1 | endothelial PAS domain protein 1 | 0.0246489 |
| LAMA4 | laminin, alpha 4 | 0.0246091 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0244415 |
| SMTN | smoothelin | 0.0243305 |
| CYTH1 | cytohesin 1 | 0.0242712 |
| OSMR | oncostatin M receptor | 0.0242273 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241155 |
| KIAA1217 | KIAA1217 | 0.0239416 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | 0.0235108 |
| SPAG9 | sperm associated antigen 9 | 0.023191 |
| RPL4 | ribosomal protein L4 | 0.0230911 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0230215 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.0230087 |
| EPHA2 | EPH receptor A2 | 0.0228172 |
| C1D | C1D nuclear receptor corepressor | 0.0225562 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0225239 |
| ADM | adrenomedullin | 0.0224765 |
| KRT18 | keratin 18, type I | 0.0223608 |
| LAMB3 | laminin, beta 3 | 0.0222017 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.0221349 |
| KMT2D | lysine (K)-specific methyltransferase 2D | 0.0220826 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0218805 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.021648 |
| PCBP2 | poly(rC) binding protein 2 | 0.0213108 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0211193 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0210557 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0209391 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | 0.0208547 |
| QSOX1 | quiescin Q6 sulfhydryl oxidase 1 | 0.0206334 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0205924 |
| TPM3 | tropomyosin 3 | 0.0203715 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0200825 |
| PLAU | plasminogen activator, urokinase | 0.0200324 |
| FBRS | fibrosin | 0.0200105 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0199325 |
| MAGEA4 | melanoma antigen family A4 | 0.0198318 |
| OGT | O-linked N-acetylglucosamine (GlcNAc) transferase | 0.0198318 |
| NGLY1 | N-glycanase 1 | 0.019777 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0197648 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0197425 |
| KRT8 | keratin 8, type II | 0.0192784 |
| NFKB1 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 1 | 0.0191759 |
| HLA-B | major histocompatibility complex, class I, B | 0.0190412 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | 0.0189852 |
| RPS17 | ribosomal protein S17 | 0.0189034 |
| MKNK2 | MAP kinase interacting serine/threonine kinase 2 | 0.0187074 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0185825 |
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.290868 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.143727 |
| TXNRD1 | thioredoxin reductase 1 | -0.12068 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.115502 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0951947 |
| CANX | calnexin | -0.0604231 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0531014 |
| H1-0 | H1.0 linker histone | -0.0463364 |
| CAV1 | caveolin 1, caveolae protein, 22kDa | -0.043717 |
| HDLBP | high density lipoprotein binding protein | -0.041431 |
| ASPH | aspartate beta-hydroxylase | -0.0386689 |
| LRP1B | low density lipoprotein receptor-related protein 1B | -0.0381586 |
| RPLP0 | ribosomal protein, large, P0 | -0.0380706 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0375782 |
| RPLP1 | ribosomal protein, large, P1 | -0.0369597 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0354974 |
| RPL34 | ribosomal protein L34 | -0.0352684 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0336829 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0336351 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0335518 |
| RPS24 | ribosomal protein S24 | -0.0335108 |
| FTL | ferritin, light polypeptide | -0.033302 |
| MXI1 | MAX interactor 1, dimerization protein | -0.0326121 |
| AKR1C1 | aldo-keto reductase family 1, member C1 | -0.0317773 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | -0.031739 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.031475 |
| RAB1A | RAB1A, member RAS oncogene family | -0.0308828 |
| HBP1 | HMG-box transcription factor 1 | -0.0306568 |
| PATJ | PATJ crumbs cell polarity complex component | -0.0303472 |
| RPS8 | ribosomal protein S8 | -0.0299621 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0285126 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0283175 |
| GM2A | GM2 ganglioside activator | -0.0282933 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.027786 |
| ARF1 | ADP-ribosylation factor 1 | -0.0277585 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0276575 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0270177 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | -0.02675 |
| KMT2A | lysine (K)-specific methyltransferase 2A | -0.0266136 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0265133 |
| PDIA6 | protein disulfide isomerase family A, member 6 | -0.0261846 |
| COPB2 | coatomer protein complex, subunit beta 2 (beta prime) | -0.0258672 |
| TPD52 | tumor protein D52 | -0.025692 |
| LDHA | lactate dehydrogenase A | -0.0256815 |
| RAB10 | RAB10, member RAS oncogene family | -0.0252091 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0251864 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0250765 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.024674 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0246207 |
| MYOF | myoferlin | -0.0245542 |
| BBX | bobby sox homolog (Drosophila) | -0.0245325 |
| UGDH | UDP-glucose 6-dehydrogenase | -0.0243448 |
| RPS25 | ribosomal protein S25 | -0.0240991 |
| TLK1 | tousled-like kinase 1 | -0.0234192 |
| NBEAL1 | neurobeachin-like 1 | -0.0230398 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0230369 |
| HILPDA | hypoxia inducible lipid droplet-associated | -0.0227984 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0226047 |
| ENO1 | enolase 1, (alpha) | -0.0224826 |
| RIMS2 | regulating synaptic membrane exocytosis 2 | -0.0222556 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.022193 |
| SPDYA | speedy/RINGO cell cycle regulator family member A | -0.0221563 |
| UVRAG | UV radiation resistance associated | -0.0221158 |
| PTMA | prothymosin, alpha | -0.0219469 |
| AHNAK | AHNAK nucleoprotein | -0.021941 |
| LRP12 | low density lipoprotein receptor-related protein 12 | -0.0219157 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.0218662 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0217118 |
| AGR2 | anterior gradient 2 | -0.0213031 |
| RLF | rearranged L-myc fusion | -0.0212437 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0212145 |
| CNOT2 | CCR4-NOT transcription complex, subunit 2 | -0.0208582 |
| MYL12A | myosin, light chain 12A, regulatory, non-sarcomeric | -0.020802 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0206329 |
| NF1 | neurofibromin 1 | -0.0205948 |
| PJA2 | praja ring finger 2, E3 ubiquitin protein ligase | -0.0205675 |
| TKT | transketolase | -0.0205285 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0205176 |
| TMTC2 | transmembrane and tetratricopeptide repeat containing 2 | -0.0204526 |
| BTG1 | B-cell translocation gene 1, anti-proliferative | -0.0204247 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0203547 |
| RPL31 | ribosomal protein L31 | -0.0202996 |
| HMGA1 | high mobility group AT-hook 1 | -0.0202813 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0202708 |
| SRP54 | signal recognition particle 54kDa | -0.0202486 |
| BZW1 | basic leucine zipper and W2 domains 1 | -0.0202266 |
| WASF2 | WAS protein family, member 2 | -0.0202175 |
| PNRC1 | proline-rich nuclear receptor coactivator 1 | -0.0201955 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0201941 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.0199192 |
| CEP350 | centrosomal protein 350kDa | -0.0197843 |
| RBM39 | RNA binding motif protein 39 | -0.019473 |
| PUM2 | pumilio RNA-binding family member 2 | -0.0194686 |
| ZNF292 | zinc finger protein 292 | -0.0193799 |
| NUMB | numb homolog (Drosophila) | -0.0193529 |
| SRP72 | signal recognition particle 72kDa | -0.0192504 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0190768 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0188487 |
| SEC24A | SEC24 family member A | -0.0187103 |
| LGALS12 | lectin, galactoside-binding, soluble, 12 | -0.0185054 |
