| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in NCI-H2030 cell line (Tahoe Therapeutics) |
| Similar Terms | |
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200 genes differentially expressed following the Delamanid_NCI-H2030 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.462159 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.117341 |
| ACTG1 | actin gamma 1 | 0.11392 |
| CALR | calreticulin | 0.0847112 |
| TPM3 | tropomyosin 3 | 0.0599753 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.059031 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | 0.056877 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0526009 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0519795 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0517702 |
| FGB | fibrinogen beta chain | 0.0513351 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.051219 |
| FLNB | filamin B, beta | 0.0509081 |
| APP | amyloid beta (A4) precursor protein | 0.0499994 |
| ADM | adrenomedullin | 0.049525 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0485458 |
| FLNA | filamin A, alpha | 0.0480222 |
| RPL3 | ribosomal protein L3 | 0.0469049 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.046227 |
| CCNL1 | cyclin L1 | 0.0451952 |
| COPA | coatomer protein complex, subunit alpha | 0.0435194 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0416862 |
| MCL1 | myeloid cell leukemia 1 | 0.0396349 |
| FMNL2 | formin-like 2 | 0.03847 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0357839 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0349863 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.0338041 |
| BRD2 | bromodomain containing 2 | 0.0331295 |
| CMIP | c-Maf inducing protein | 0.0328102 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0306642 |
| PYGL | phosphorylase, glycogen, liver | 0.0306535 |
| RPL4 | ribosomal protein L4 | 0.0302972 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.0299599 |
| ACTN1 | actinin, alpha 1 | 0.0297728 |
| SPAG5 | sperm associated antigen 5 | 0.029507 |
| SMOC1 | SPARC related modular calcium binding 1 | 0.0286664 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0285118 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0284996 |
| THBS1 | thrombospondin 1 | 0.0284129 |
| PRPF8 | pre-mRNA processing factor 8 | 0.028155 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.0268365 |
| POTEF | POTE ankyrin domain family, member F | 0.0267671 |
| TMSB4X | thymosin beta 4, X-linked | 0.0267449 |
| HDGF | hepatoma-derived growth factor | 0.0266572 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.0264318 |
| DDX39B | DEAD (Asp-Glu-Ala-Asp) box polypeptide 39B | 0.0264225 |
| PRRC2A | proline-rich coiled-coil 2A | 0.0256615 |
| RBM8A | RNA binding motif protein 8A | 0.0255561 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0255446 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0250935 |
| HLA-B | major histocompatibility complex, class I, B | 0.0249074 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0242863 |
| SFTPA2 | surfactant protein A2 | 0.0238261 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0234663 |
| SDC4 | syndecan 4 | 0.022706 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0220121 |
| SMAD3 | SMAD family member 3 | 0.0218664 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.0217297 |
| TPM4 | tropomyosin 4 | 0.0213035 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0210877 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.021048 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0206355 |
| JUN | jun proto-oncogene | 0.0205172 |
| RPL7A | ribosomal protein L7a | 0.0203011 |
| CASC3 | cancer susceptibility candidate 3 | 0.0202515 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0201251 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0200499 |
| MSN | moesin | 0.0198977 |
| EGFR | epidermal growth factor receptor | 0.0198584 |
| HLA-C | major histocompatibility complex, class I, C | 0.0196236 |
| MEF2D | myocyte enhancer factor 2D | 0.0190077 |
| PLEC | plectin | 0.018977 |
| PTMA | prothymosin, alpha | 0.0189525 |
| LAMC2 | laminin, gamma 2 | 0.0185171 |
| FOSB | FBJ murine osteosarcoma viral oncogene homolog B | 0.0184894 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0182742 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0182357 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0181288 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0179578 |
| HLA-A | major histocompatibility complex, class I, A | 0.0178741 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0178592 |
| DCTN1 | dynactin 1 | 0.0177593 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0177505 |
| PNN | pinin, desmosome associated protein | 0.0176493 |
| NDRG1 | N-myc downstream regulated 1 | 0.0175085 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0174763 |
| USP36 | ubiquitin specific peptidase 36 | 0.0173217 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0169931 |
| YBX1 | Y box binding protein 1 | 0.0169718 |
| VEGFA | vascular endothelial growth factor A | 0.0166952 |
| CCNY | cyclin Y | 0.0165376 |
| HYOU1 | hypoxia up-regulated 1 | 0.0163236 |
| EIF3A | eukaryotic translation initiation factor 3, subunit A | 0.0162729 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0160954 |
| ANGPTL4 | angiopoietin-like 4 | 0.0160475 |
| HNRNPH3 | heterogeneous nuclear ribonucleoprotein H3 (2H9) | 0.0159782 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0159613 |
| EGR1 | early growth response 1 | 0.0159189 |
| CTBP2 | C-terminal binding protein 2 | 0.0158743 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0157665 |
| Symbol | Name | Standardized Value |
|---|---|---|
| FTL | ferritin, light polypeptide | -0.191123 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.181838 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.153602 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.131098 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.118173 |
| TXNRD1 | thioredoxin reductase 1 | -0.114697 |
| VIM | vimentin | -0.0865142 |
| TMSB10 | thymosin beta 10 | -0.0806659 |
| PM20D1 | peptidase M20 domain containing 1 | -0.0783316 |
| RPLP1 | ribosomal protein, large, P1 | -0.0781309 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.072076 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0696631 |
| RPLP0 | ribosomal protein, large, P0 | -0.0613008 |
| RPS21 | ribosomal protein S21 | -0.058852 |
| S100A6 | S100 calcium binding protein A6 | -0.0544656 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.0443429 |
| GRAMD1B | GRAM domain containing 1B | -0.0443396 |
| RPS27A | ribosomal protein S27a | -0.0426525 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0415681 |
| RPS5 | ribosomal protein S5 | -0.0406133 |
| NQO1 | NAD(P)H dehydrogenase, quinone 1 | -0.0401507 |
| RPS25 | ribosomal protein S25 | -0.0400906 |
| PFN1 | profilin 1 | -0.0396367 |
| IER3 | immediate early response 3 | -0.039125 |
| RPS12 | ribosomal protein S12 | -0.0386841 |
| RPS24 | ribosomal protein S24 | -0.0385844 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0382136 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0377042 |
| RPS8 | ribosomal protein S8 | -0.0376735 |
| LANCL1 | LanC lantibiotic synthetase component C-like 1 (bacterial) | -0.0371838 |
| TM4SF1 | transmembrane 4 L six family member 1 | -0.0369853 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | -0.0362225 |
| ROBO2 | roundabout, axon guidance receptor, homolog 2 (Drosophila) | -0.0357628 |
| RAD21 | RAD21 homolog (S. pombe) | -0.0338218 |
| WWOX | WW domain containing oxidoreductase | -0.0338014 |
| RPL34 | ribosomal protein L34 | -0.0337375 |
| RPS2 | ribosomal protein S2 | -0.0336731 |
| RPL7 | ribosomal protein L7 | -0.0323064 |
| MT2A | metallothionein 2A | -0.0320955 |
| RPL30 | ribosomal protein L30 | -0.0312746 |
| RPS16 | ribosomal protein S16 | -0.0306724 |
| RPS20 | ribosomal protein S20 | -0.0305214 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0302843 |
| BICC1 | BicC family RNA binding protein 1 | -0.0299589 |
| RPL35A | ribosomal protein L35a | -0.0299022 |
| RPL26 | ribosomal protein L26 | -0.0296674 |
| AHR | aryl hydrocarbon receptor | -0.0296028 |
| C15ORF48 | chromosome 15 open reading frame 48 | -0.029504 |
| NOP58 | NOP58 ribonucleoprotein | -0.0292091 |
| S100A9 | S100 calcium binding protein A9 | -0.0289404 |
| RPL23 | ribosomal protein L23 | -0.0286668 |
| RPL37 | ribosomal protein L37 | -0.0284698 |
| SEMA3A | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3A | -0.0284563 |
| RBM39 | RNA binding motif protein 39 | -0.0283222 |
| MYL12B | myosin, light chain 12B, regulatory | -0.0282509 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0276834 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0274794 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0274246 |
| HMGB1 | high mobility group box 1 | -0.0272638 |
| RPS23 | ribosomal protein S23 | -0.027111 |
| RACK1 | receptor for activated C kinase 1 | -0.0270102 |
| RPS15 | ribosomal protein S15 | -0.0267716 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0264796 |
| ZNF292 | zinc finger protein 292 | -0.0264603 |
| RPL11 | ribosomal protein L11 | -0.0264415 |
| TRA2A | transformer 2 alpha homolog (Drosophila) | -0.0257147 |
| RPL23A | ribosomal protein L23a | -0.025643 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0251857 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0241526 |
| NNMT | nicotinamide N-methyltransferase | -0.0241071 |
| ASPH | aspartate beta-hydroxylase | -0.0240368 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0240246 |
| NRG1 | neuregulin 1 | -0.0238393 |
| SEPTIN7 | septin 7 | -0.0235393 |
| RPLP2 | ribosomal protein, large, P2 | -0.0231764 |
| SRGN | serglycin | -0.0230946 |
| S100A10 | S100 calcium binding protein A10 | -0.0230868 |
| EFNA5 | ephrin-A5 | -0.0229748 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0229366 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0226288 |
| RAN | RAN, member RAS oncogene family | -0.0226009 |
| ADGRG6 | adhesion G protein-coupled receptor G6 | -0.0223832 |
| TMEM123 | transmembrane protein 123 | -0.0223288 |
| TUBA1B | tubulin, alpha 1b | -0.0222418 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0219076 |
| QKI | QKI, KH domain containing, RNA binding | -0.0216813 |
| SLC38A2 | solute carrier family 38, member 2 | -0.0216048 |
| RPL19 | ribosomal protein L19 | -0.0215598 |
| CAVIN1 | caveolae associated protein 1 | -0.021387 |
| RPL31 | ribosomal protein L31 | -0.0213548 |
| NCOA7 | nuclear receptor coactivator 7 | -0.0210081 |
| DENND4A | DENN/MADD domain containing 4A | -0.0209964 |
| RPL5 | ribosomal protein L5 | -0.0208383 |
| RPL32 | ribosomal protein L32 | -0.0205436 |
| BIRC2 | baculoviral IAP repeat containing 2 | -0.0205097 |
| NEGR1 | neuronal growth regulator 1 | -0.0204007 |
| ENO1 | enolase 1, (alpha) | -0.0202677 |
| SRGAP1 | SLIT-ROBO Rho GTPase activating protein 1 | -0.0202287 |
| CENPF | centromere protein F, 350/400kDa | -0.0201304 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0200904 |
