| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in NCI-H596 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_NCI-H596 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | 0.193367 |
| NDRG1 | N-myc downstream regulated 1 | 0.168651 |
| DTNA | dystrobrevin, alpha | 0.135151 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.114905 |
| EIF4A1 | eukaryotic translation initiation factor 4A1 | 0.11194 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.109022 |
| SIPA1L3 | signal-induced proliferation-associated 1 like 3 | 0.108911 |
| PPP2R2A | protein phosphatase 2, regulatory subunit B, alpha | 0.10778 |
| HELZ | helicase with zinc finger | 0.10313 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0997382 |
| S100A6 | S100 calcium binding protein A6 | 0.0974966 |
| GNAS | GNAS complex locus | 0.0972038 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0971949 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | 0.0946118 |
| B2M | beta-2-microglobulin | 0.0930582 |
| SPAG9 | sperm associated antigen 9 | 0.0925155 |
| PGK1 | phosphoglycerate kinase 1 | 0.0891082 |
| CALR | calreticulin | 0.088253 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | 0.08715 |
| CLTC | clathrin, heavy chain (Hc) | 0.0869628 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0863212 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | 0.0798394 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | 0.0796498 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0795956 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0789124 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0735537 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0711429 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0653915 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.060788 |
| ACTG1 | actin gamma 1 | 0.0592019 |
| RBM39 | RNA binding motif protein 39 | 0.0577098 |
| FAM13A | family with sequence similarity 13, member A | 0.0574496 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.056705 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | 0.0561181 |
| MYO1E | myosin IE | 0.0557468 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | 0.0548014 |
| SLC38A1 | solute carrier family 38, member 1 | 0.0541173 |
| OGA | O-GlcNAcase | 0.053945 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0537877 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0537171 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0527804 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0522666 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0490974 |
| MORF4L2 | mortality factor 4 like 2 | 0.0488949 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0481376 |
| PARD3 | par-3 family cell polarity regulator | 0.0468677 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0465661 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.044765 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0439512 |
| PTK2 | protein tyrosine kinase 2 | 0.043674 |
| NCOA3 | nuclear receptor coactivator 3 | 0.0424386 |
| PFKFB4 | 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 | 0.0414974 |
| MT2A | metallothionein 2A | 0.0411051 |
| SLTM | SAFB-like, transcription modulator | 0.0390563 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0379684 |
| CDH13 | cadherin 13 | 0.0376299 |
| TMSB10 | thymosin beta 10 | 0.0374893 |
| ANXA2 | annexin A2 | 0.0359796 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.0354475 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0349654 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0303836 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0301196 |
| TMEM165 | transmembrane protein 165 | 0.0300373 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0289718 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0279202 |
| USP34 | ubiquitin specific peptidase 34 | 0.0274707 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0266268 |
| ZNF292 | zinc finger protein 292 | 0.024664 |
| MRPS6 | mitochondrial ribosomal protein S6 | 0.0236155 |
| PKM | pyruvate kinase, muscle | 0.0235596 |
| DLG1 | discs, large homolog 1 (Drosophila) | 0.0222685 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0221485 |
| UBC | ubiquitin C | 0.0215852 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0214743 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0208697 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0196356 |
| RPLP1 | ribosomal protein, large, P1 | 0.0193044 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0181903 |
| CANX | calnexin | 0.0180236 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0178922 |
| GOLGA4 | golgin A4 | 0.0175506 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0164276 |
| WDFY3 | WD repeat and FYVE domain containing 3 | 0.0159112 |
| PICALM | phosphatidylinositol binding clathrin assembly protein | 0.0145599 |
| RPL19 | ribosomal protein L19 | 0.0126436 |
| ERRFI1 | ERBB receptor feedback inhibitor 1 | 0.012474 |
| GLIS3 | GLIS family zinc finger 3 | 0.0108249 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.00991138 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | 0.00918262 |
| MED13L | mediator complex subunit 13-like | 0.00900556 |
| MYOF | myoferlin | 0.00769205 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.00671934 |
| PTPN12 | protein tyrosine phosphatase, non-receptor type 12 | 0.00591718 |
| ANKRD11 | ankyrin repeat domain 11 | 0.00583977 |
| ASPH | aspartate beta-hydroxylase | 0.00542856 |
| COL6A1 | collagen, type VI, alpha 1 | 0.00465115 |
| RABGEF1 | RAB guanine nucleotide exchange factor (GEF) 1 | 0.00410419 |
| AHNAK | AHNAK nucleoprotein | 0.00404661 |
| RUNX1 | runt-related transcription factor 1 | 0.00353956 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.00320881 |
| Symbol | Name | Standardized Value |
|---|---|---|
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.187283 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | -0.146282 |
| VIM | vimentin | -0.143163 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.117153 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.115978 |
| MCL1 | myeloid cell leukemia 1 | -0.113115 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0965843 |
| JMJD1C | jumonji domain containing 1C | -0.0925498 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.0912328 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0891019 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | -0.0857785 |
| PRKCA | protein kinase C, alpha | -0.0839772 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | -0.0828996 |
| H3-3B | H3.3 histone B | -0.0794813 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0791961 |
| ENO1 | enolase 1, (alpha) | -0.0777314 |
| ARB2A | ARB2 cotranscriptional regulator A | -0.0744646 |
| RPS6 | ribosomal protein S6 | -0.0734985 |
| ITGA6 | integrin, alpha 6 | -0.0720755 |
| PDE10A | phosphodiesterase 10A | -0.0716982 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | -0.0706794 |
| MACF1 | microtubule-actin crosslinking factor 1 | -0.0676016 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0660007 |
| INHBA | inhibin, beta A | -0.0651102 |
| MYO10 | myosin X | -0.062642 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.0620584 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0577406 |
| VCL | vinculin | -0.0577055 |
| RPL35A | ribosomal protein L35a | -0.0572662 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0572057 |
| PTMA | prothymosin, alpha | -0.0551101 |
| CD44 | CD44 molecule (Indian blood group) | -0.0541623 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | -0.0536306 |
| DST | dystonin | -0.0527281 |
| DOCK4 | dedicator of cytokinesis 4 | -0.0525652 |
| BIRC6 | baculoviral IAP repeat containing 6 | -0.0521012 |
| RPS8 | ribosomal protein S8 | -0.0511924 |
| EFNA5 | ephrin-A5 | -0.0510502 |
| COL6A3 | collagen, type VI, alpha 3 | -0.0509968 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0456409 |
| NALF1 | NALCN channel auxiliary factor 1 | -0.045627 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.0451517 |
| DPP10 | dipeptidyl-peptidase 10 (non-functional) | -0.0438878 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0426514 |
| LIMS1 | LIM and senescent cell antigen-like domains 1 | -0.0415314 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | -0.041002 |
| ZNF609 | zinc finger protein 609 | -0.0399749 |
| OXR1 | oxidation resistance 1 | -0.0394507 |
| ARID2 | AT rich interactive domain 2 (ARID, RFX-like) | -0.0387365 |
| SMYD3 | SET and MYND domain containing 3 | -0.0372846 |
| HMGA2 | high mobility group AT-hook 2 | -0.0358734 |
| ADAMTS6 | ADAM metallopeptidase with thrombospondin type 1 motif, 6 | -0.0317715 |
| MYCBP2 | MYC binding protein 2, E3 ubiquitin protein ligase | -0.0312963 |
| ANKHD1 | ankyrin repeat and KH domain containing 1 | -0.0308361 |
| GLG1 | golgi glycoprotein 1 | -0.0304411 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | -0.0299147 |
| FTL | ferritin, light polypeptide | -0.0289608 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | -0.027918 |
| FN1 | fibronectin 1 | -0.0275807 |
| ANKRD12 | ankyrin repeat domain 12 | -0.0267552 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0259591 |
| CEP170 | centrosomal protein 170kDa | -0.0255605 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | -0.0250643 |
| VMP1 | vacuole membrane protein 1 | -0.0247078 |
| SPIDR | scaffolding protein involved in DNA repair | -0.0237073 |
| RPL37A | ribosomal protein L37a | -0.0228055 |
| RPS12 | ribosomal protein S12 | -0.0226602 |
| GPC6 | glypican 6 | -0.020873 |
| SQSTM1 | sequestosome 1 | -0.0204163 |
| RBPJ | recombination signal binding protein for immunoglobulin kappa J region | -0.0201222 |
| TNKS | tankyrase, TRF1-interacting ankyrin-related ADP-ribose polymerase | -0.0193877 |
| CUX1 | cut-like homeobox 1 | -0.0170992 |
| EGFR | epidermal growth factor receptor | -0.0169291 |
| OSMR | oncostatin M receptor | -0.016512 |
| LMO7 | LIM domain 7 | -0.0162236 |
| MAML3 | mastermind-like 3 (Drosophila) | -0.0155991 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0150705 |
| BACE2 | beta-site APP-cleaving enzyme 2 | -0.0148981 |
| MMAB | methylmalonic aciduria (cobalamin deficiency) cblB type | -0.0144092 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0128282 |
| POTEF | POTE ankyrin domain family, member F | -0.0117448 |
| TTC3 | tetratricopeptide repeat domain 3 | -0.0112012 |
| STC1 | stanniocalcin 1 | -0.00978006 |
| SETD5 | SET domain containing 5 | -0.0096164 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.00837046 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.00823838 |
| REV3L | REV3-like, polymerase (DNA directed), zeta, catalytic subunit | -0.00801553 |
| ZFHX3 | zinc finger homeobox 3 | -0.00771198 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.00758771 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.00531401 |
| ESYT2 | extended synaptotagmin-like protein 2 | -0.0052066 |
| SND1 | staphylococcal nuclease and tudor domain containing 1 | -0.00487492 |
| PPFIBP1 | PTPRF interacting protein, binding protein 1 (liprin beta 1) | -0.0045036 |
| GPHN | gephyrin | -0.00447143 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.00414326 |
| RPL11 | ribosomal protein L11 | -0.00346342 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.00316107 |
| TXNRD1 | thioredoxin reductase 1 | -0.0017183 |
| EEF2 | eukaryotic translation elongation factor 2 | -0.00170993 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -2.53597E-4 |
