| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in NCI-H661 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_NCI-H661 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.212074 |
| THBS1 | thrombospondin 1 | 0.161025 |
| CALR | calreticulin | 0.143973 |
| COL11A1 | collagen, type XI, alpha 1 | 0.125705 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.122662 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.118028 |
| PTMA | prothymosin, alpha | 0.0904321 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0893294 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0849724 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0808644 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0640566 |
| ACTG1 | actin gamma 1 | 0.0626867 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0595944 |
| APP | amyloid beta (A4) precursor protein | 0.0554769 |
| COL3A1 | collagen, type III, alpha 1 | 0.0528025 |
| COL5A2 | collagen, type V, alpha 2 | 0.0519793 |
| PRPF8 | pre-mRNA processing factor 8 | 0.0515912 |
| CTNNA2 | catenin (cadherin-associated protein), alpha 2 | 0.0513075 |
| FLNA | filamin A, alpha | 0.0503841 |
| ZEB2 | zinc finger E-box binding homeobox 2 | 0.0500818 |
| GSE1 | Gse1 coiled-coil protein | 0.0470985 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0463656 |
| NTM | neurotrimin | 0.0451715 |
| CCN2 | cellular communication network factor 2 | 0.0447167 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0443491 |
| RFPL4B | ret finger protein-like 4B | 0.0442855 |
| SPAG9 | sperm associated antigen 9 | 0.0442649 |
| PCLO | piccolo presynaptic cytomatrix protein | 0.0434396 |
| ANXA2 | annexin A2 | 0.0431774 |
| GALNTL6 | polypeptide N-acetylgalactosaminyltransferase-like 6 | 0.0429887 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0421298 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0418193 |
| TPM3 | tropomyosin 3 | 0.0412564 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0409551 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0403578 |
| UPP1 | uridine phosphorylase 1 | 0.0400868 |
| HNRNPA3 | heterogeneous nuclear ribonucleoprotein A3 | 0.0383595 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0375764 |
| MAPRE1 | microtubule-associated protein, RP/EB family, member 1 | 0.0374828 |
| PCDH9 | protocadherin 9 | 0.0366697 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0363151 |
| B2M | beta-2-microglobulin | 0.0361753 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0346571 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | 0.0344418 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0343954 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0334663 |
| SFTPA2 | surfactant protein A2 | 0.0333706 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.0333576 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0330104 |
| HNRNPUL1 | heterogeneous nuclear ribonucleoprotein U-like 1 | 0.0325673 |
| RPL3 | ribosomal protein L3 | 0.0322092 |
| PRELID2 | PRELI domain containing 2 | 0.0319819 |
| PAK4 | p21 protein (Cdc42/Rac)-activated kinase 4 | 0.0317434 |
| HCN1 | hyperpolarization activated cyclic nucleotide gated potassium channel 1 | 0.0316625 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0312396 |
| TTC28 | tetratricopeptide repeat domain 28 | 0.03054 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0304407 |
| RPN1 | ribophorin I | 0.0301883 |
| SEMA3E | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3E | 0.0300859 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0298167 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0294413 |
| RALY | RALY heterogeneous nuclear ribonucleoprotein | 0.0290101 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0287805 |
| FN1 | fibronectin 1 | 0.0287462 |
| SSR1 | signal sequence receptor, alpha | 0.0286819 |
| MB21D2 | Mab-21 domain containing 2 | 0.0286045 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0284227 |
| COTL1 | coactosin-like F-actin binding protein 1 | 0.0283703 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0283566 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0280887 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0278649 |
| MCL1 | myeloid cell leukemia 1 | 0.0277313 |
| TENM2 | teneurin transmembrane protein 2 | 0.0277053 |
| IGF1R | insulin-like growth factor 1 receptor | 0.0276591 |
| SEMA3C | sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C | 0.0275749 |
| HNRNPL | heterogeneous nuclear ribonucleoprotein L | 0.0275039 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0274979 |
| HMGCS1 | 3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble) | 0.0273013 |
| STMN1 | stathmin 1 | 0.0270497 |
| ADGRV1 | adhesion G protein-coupled receptor V1 | 0.0266407 |
| DNMBP | dynamin binding protein | 0.0263648 |
| SPAG5 | sperm associated antigen 5 | 0.0261075 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0261002 |
| AHNAK | AHNAK nucleoprotein | 0.0259569 |
| PCDH7 | protocadherin 7 | 0.0258645 |
| KIF5B | kinesin family member 5B | 0.02579 |
| RPL7A | ribosomal protein L7a | 0.0256855 |
| RPL4 | ribosomal protein L4 | 0.0254839 |
| ANXA1 | annexin A1 | 0.0253565 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.0252507 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0250736 |
| SGCE | sarcoglycan, epsilon | 0.0250681 |
| SNRNP200 | small nuclear ribonucleoprotein 200kDa (U5) | 0.024924 |
| TPM4 | tropomyosin 4 | 0.0248269 |
| CNN3 | calponin 3, acidic | 0.0246581 |
| CCNL1 | cyclin L1 | 0.0246141 |
| RAD21 | RAD21 homolog (S. pombe) | 0.0242879 |
| SMG1 | SMG1 phosphatidylinositol 3-kinase-related kinase | 0.0242848 |
| MAP7D1 | MAP7 domain containing 1 | 0.0242188 |
| IVNS1ABP | influenza virus NS1A binding protein | 0.0241745 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0916035 |
| TSC22D2 | TSC22 domain family, member 2 | -0.0905303 |
| PFN1 | profilin 1 | -0.0850166 |
| PHIP | pleckstrin homology domain interacting protein | -0.0808449 |
| G2E3 | G2/M-phase specific E3 ubiquitin protein ligase | -0.0707348 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0706541 |
| RPLP1 | ribosomal protein, large, P1 | -0.0696615 |
| STRN3 | striatin, calmodulin binding protein 3 | -0.0641724 |
| MED13L | mediator complex subunit 13-like | -0.0638442 |
| RPS6 | ribosomal protein S6 | -0.0615241 |
| PGAP1 | post-GPI attachment to proteins 1 | -0.0614471 |
| RPLP0 | ribosomal protein, large, P0 | -0.0597571 |
| SRP54 | signal recognition particle 54kDa | -0.0590256 |
| ZFAND3 | zinc finger, AN1-type domain 3 | -0.0571704 |
| PUM1 | pumilio RNA-binding family member 1 | -0.0568766 |
| BMPR2 | bone morphogenetic protein receptor, type II (serine/threonine kinase) | -0.0534887 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0528577 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0514356 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | -0.0512127 |
| FBXO11 | F-box protein 11 | -0.0511787 |
| RYBP | RING1 and YY1 binding protein | -0.0510888 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0507095 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0484415 |
| CENPF | centromere protein F, 350/400kDa | -0.0466119 |
| TUBA1B | tubulin, alpha 1b | -0.0459495 |
| ZNF292 | zinc finger protein 292 | -0.0452185 |
| DENND4C | DENN/MADD domain containing 4C | -0.0446524 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0442843 |
| MTF2 | metal response element binding transcription factor 2 | -0.043321 |
| AP3B1 | adaptor-related protein complex 3, beta 1 subunit | -0.0432157 |
| KDM5B | lysine (K)-specific demethylase 5B | -0.0423461 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0423286 |
| PEG10 | paternally expressed 10 | -0.0417687 |
| NOP58 | NOP58 ribonucleoprotein | -0.0415996 |
| NIPBL | Nipped-B homolog (Drosophila) | -0.0414892 |
| RALGAPA1 | Ral GTPase activating protein, alpha subunit 1 (catalytic) | -0.0414314 |
| HMGB1 | high mobility group box 1 | -0.0414232 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0413442 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | -0.041186 |
| RPS8 | ribosomal protein S8 | -0.0409411 |
| CSE1L | CSE1 chromosome segregation 1-like (yeast) | -0.0407974 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0407161 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0407029 |
| GOLGA4 | golgin A4 | -0.0406675 |
| PRTG | protogenin | -0.0404876 |
| ZFPM2 | zinc finger protein, FOG family member 2 | -0.0399693 |
| RERE | arginine-glutamic acid dipeptide (RE) repeats | -0.0399593 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0393916 |
| TMBIM6 | transmembrane BAX inhibitor motif containing 6 | -0.0383614 |
| NFIA | nuclear factor I/A | -0.0382725 |
| RPS2 | ribosomal protein S2 | -0.0381952 |
| XPO1 | exportin 1 | -0.037981 |
| PRKD1 | protein kinase D1 | -0.0375321 |
| PSMD14 | proteasome (prosome, macropain) 26S subunit, non-ATPase, 14 | -0.0375024 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0374364 |
| RBM39 | RNA binding motif protein 39 | -0.0370067 |
| CCDC88A | coiled-coil domain containing 88A | -0.0367785 |
| GPBP1 | GC-rich promoter binding protein 1 | -0.0364156 |
| JMJD1C | jumonji domain containing 1C | -0.0359241 |
| STAG2 | stromal antigen 2 | -0.0355765 |
| SEPTIN7 | septin 7 | -0.0350755 |
| NBEAL1 | neurobeachin-like 1 | -0.0349647 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0348019 |
| POTEF | POTE ankyrin domain family, member F | -0.0346201 |
| ARHGAP15 | Rho GTPase activating protein 15 | -0.0342403 |
| PARD3B | par-3 family cell polarity regulator beta | -0.0341625 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.0334724 |
| RTN3 | reticulon 3 | -0.0328891 |
| UACA | uveal autoantigen with coiled-coil domains and ankyrin repeats | -0.0327913 |
| RPL23 | ribosomal protein L23 | -0.0324831 |
| TOR1AIP2 | torsin A interacting protein 2 | -0.0324248 |
| BRWD1 | bromodomain and WD repeat domain containing 1 | -0.0321863 |
| RPL34 | ribosomal protein L34 | -0.0319582 |
| ZC3H15 | zinc finger CCCH-type containing 15 | -0.0319476 |
| RDX | radixin | -0.0315536 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0315381 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.031393 |
| HMGB2 | high mobility group box 2 | -0.0310228 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0309182 |
| MEIS2 | Meis homeobox 2 | -0.0308653 |
| VCL | vinculin | -0.0307997 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | -0.0307728 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.030757 |
| RPS20 | ribosomal protein S20 | -0.0302588 |
| MAP1LC3B | microtubule-associated protein 1 light chain 3 beta | -0.0299089 |
| USP14 | ubiquitin specific peptidase 14 (tRNA-guanine transglycosylase) | -0.0298838 |
| UBB | ubiquitin B | -0.0296599 |
| ASTN2 | astrotactin 2 | -0.0294365 |
| ERBIN | erbb2 interacting protein | -0.0292762 |
| RPS14 | ribosomal protein S14 | -0.0290585 |
| FOXP2 | forkhead box P2 | -0.0290302 |
| PGK1 | phosphoglycerate kinase 1 | -0.0288585 |
| UBE2K | ubiquitin-conjugating enzyme E2K | -0.0283676 |
| SHROOM3 | shroom family member 3 | -0.0283361 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0282574 |
| LDHA | lactate dehydrogenase A | -0.0279895 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0279866 |
| NUP155 | nucleoporin 155kDa | -0.0279495 |
| SNX6 | sorting nexin 6 | -0.027903 |
| OSBPL8 | oxysterol binding protein-like 8 | -0.0278951 |
