| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in SNU-1 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_SNU-1 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TMSB4X | thymosin beta 4, X-linked | 0.333563 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.202464 |
| EIF4A2 | eukaryotic translation initiation factor 4A2 | 0.0749875 |
| FLNB | filamin B, beta | 0.0722443 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0722263 |
| RPL3 | ribosomal protein L3 | 0.0698596 |
| PTMA | prothymosin, alpha | 0.0691704 |
| PDE4B | phosphodiesterase 4B, cAMP-specific | 0.0581859 |
| ACTG1 | actin gamma 1 | 0.0575925 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0571899 |
| CAMTA1 | calmodulin binding transcription activator 1 | 0.0547183 |
| FBLN2 | fibulin 2 | 0.0535895 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0523145 |
| EZR | ezrin | 0.0503205 |
| PRELID2 | PRELI domain containing 2 | 0.0498986 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.049632 |
| HSPA9 | heat shock 70kDa protein 9 (mortalin) | 0.0495937 |
| ENO2 | enolase 2 (gamma, neuronal) | 0.0494203 |
| PLEKHA4 | pleckstrin homology domain containing, family A (phosphoinositide binding specific) member 4 | 0.0477977 |
| GNPDA1 | glucosamine-6-phosphate deaminase 1 | 0.0466816 |
| CALR | calreticulin | 0.0446009 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0438375 |
| APP | amyloid beta (A4) precursor protein | 0.0427311 |
| PLXNA1 | plexin A1 | 0.0424116 |
| HDAC9 | histone deacetylase 9 | 0.0416938 |
| TMEM65 | transmembrane protein 65 | 0.0395655 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0395009 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.0379231 |
| MYOF | myoferlin | 0.0376482 |
| TBC1D22A | TBC1 domain family, member 22A | 0.0370416 |
| ARHGEF10 | Rho guanine nucleotide exchange factor (GEF) 10 | 0.0369964 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0348291 |
| RPL7A | ribosomal protein L7a | 0.0344624 |
| PPP3CA | protein phosphatase 3, catalytic subunit, alpha isozyme | 0.0340812 |
| EEF1G | eukaryotic translation elongation factor 1 gamma | 0.033281 |
| CSF1 | colony stimulating factor 1 (macrophage) | 0.0332013 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0330665 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.03286 |
| DUSP4 | dual specificity phosphatase 4 | 0.0321947 |
| GLI2 | GLI family zinc finger 2 | 0.0316546 |
| SOX6 | SRY (sex determining region Y)-box 6 | 0.0312648 |
| LOXL3 | lysyl oxidase-like 3 | 0.0311624 |
| CEP250 | centrosomal protein 250kDa | 0.0308175 |
| NFKB2 | nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100) | 0.0300695 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.029675 |
| DENND1A | DENN/MADD domain containing 1A | 0.0295332 |
| DNAJC5 | DnaJ (Hsp40) homolog, subfamily C, member 5 | 0.0291372 |
| AHNAK | AHNAK nucleoprotein | 0.0287949 |
| YEATS2 | YEATS domain containing 2 | 0.0281868 |
| AMOTL2 | angiomotin like 2 | 0.0281555 |
| MKI67 | marker of proliferation Ki-67 | 0.0280913 |
| PRPF38B | pre-mRNA processing factor 38B | 0.0280173 |
| NFE2L1 | nuclear factor, erythroid 2-like 1 | 0.0275595 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | 0.0270535 |
| GSE1 | Gse1 coiled-coil protein | 0.026764 |
| ASPHD1 | aspartate beta-hydroxylase domain containing 1 | 0.0263651 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0263538 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0261679 |
| VEGFA | vascular endothelial growth factor A | 0.0258502 |
| PTTG1IP | pituitary tumor-transforming 1 interacting protein | 0.0257854 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0254811 |
| FAT1 | FAT atypical cadherin 1 | 0.0248171 |
| RPS4Y1 | ribosomal protein S4, Y-linked 1 | 0.0246223 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0245222 |
| CD47 | CD47 molecule | 0.0244746 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0244018 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0242662 |
| FAM13A | family with sequence similarity 13, member A | 0.024063 |
| BNIP3 | BCL2/adenovirus E1B 19kDa interacting protein 3 | 0.0239337 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.023904 |
| ANXA3 | annexin A3 | 0.0238602 |
| FLNA | filamin A, alpha | 0.0237321 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0234465 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0232742 |
| CTIF | CBP80/20-dependent translation initiation factor | 0.0232568 |
| UNC13A | unc-13 homolog A (C. elegans) | 0.0229873 |
| TRIM44 | tripartite motif containing 44 | 0.0228671 |
| BRD2 | bromodomain containing 2 | 0.0226287 |
| MAFF | v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog F | 0.0225741 |
| PDGFC | platelet derived growth factor C | 0.0225137 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0221376 |
| SFTPA2 | surfactant protein A2 | 0.0220712 |
| HDLBP | high density lipoprotein binding protein | 0.0218864 |
| TPM4 | tropomyosin 4 | 0.0214189 |
| SUPT5H | suppressor of Ty 5 homolog (S. cerevisiae) | 0.021417 |
| PMM2 | phosphomannomutase 2 | 0.0213625 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0213107 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0212389 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.020882 |
| ARFGAP1 | ADP-ribosylation factor GTPase activating protein 1 | 0.0206 |
| DYNC1H1 | dynein, cytoplasmic 1, heavy chain 1 | 0.0204831 |
| CASC3 | cancer susceptibility candidate 3 | 0.0201519 |
| CACNB4 | calcium channel, voltage-dependent, beta 4 subunit | 0.0200912 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0200024 |
| FNIP1 | folliculin interacting protein 1 | 0.0198611 |
| GOLGA3 | golgin A3 | 0.0198527 |
| MYL6 | myosin, light chain 6, alkali, smooth muscle and non-muscle | 0.0198031 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0195322 |
| RPL4 | ribosomal protein L4 | 0.0195309 |
| ADAM10 | ADAM metallopeptidase domain 10 | 0.01945 |
| Symbol | Name | Standardized Value |
|---|---|---|
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.208214 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.15183 |
| RPS6 | ribosomal protein S6 | -0.0930743 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.091432 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0861642 |
| S100A6 | S100 calcium binding protein A6 | -0.0790097 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0778193 |
| RPLP0 | ribosomal protein, large, P0 | -0.0776687 |
| RPL34 | ribosomal protein L34 | -0.0721809 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0717346 |
| RPLP1 | ribosomal protein, large, P1 | -0.0586091 |
| PFN1 | profilin 1 | -0.0582965 |
| RPLP2 | ribosomal protein, large, P2 | -0.0553405 |
| RPS8 | ribosomal protein S8 | -0.0504195 |
| RPS13 | ribosomal protein S13 | -0.0492957 |
| RPL31 | ribosomal protein L31 | -0.0478028 |
| PKM | pyruvate kinase, muscle | -0.0473769 |
| RPL35A | ribosomal protein L35a | -0.0463983 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | -0.0453123 |
| S100A4 | S100 calcium binding protein A4 | -0.0452733 |
| RPL27A | ribosomal protein L27a | -0.0447088 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0443851 |
| RPS24 | ribosomal protein S24 | -0.0437237 |
| RPS19 | ribosomal protein S19 | -0.0426462 |
| ZNF292 | zinc finger protein 292 | -0.0411186 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.039529 |
| RPS25 | ribosomal protein S25 | -0.0390396 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | -0.0378577 |
| RPS27A | ribosomal protein S27a | -0.0376464 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.0375176 |
| RPS21 | ribosomal protein S21 | -0.0375159 |
| RPS12 | ribosomal protein S12 | -0.0363975 |
| RBM39 | RNA binding motif protein 39 | -0.0362312 |
| MATR3 | matrin 3 | -0.0360283 |
| HSPH1 | heat shock 105kDa/110kDa protein 1 | -0.0357516 |
| FOXP1 | forkhead box P1 | -0.0352198 |
| ARL6IP1 | ADP-ribosylation factor-like 6 interacting protein 1 | -0.0350554 |
| JMJD1C | jumonji domain containing 1C | -0.034899 |
| RPL12 | ribosomal protein L12 | -0.0347347 |
| TAX1BP1 | Tax1 (human T-cell leukemia virus type I) binding protein 1 | -0.0339798 |
| RPS2 | ribosomal protein S2 | -0.0338406 |
| S100A9 | S100 calcium binding protein A9 | -0.032807 |
| RPS23 | ribosomal protein S23 | -0.0321588 |
| RPL11 | ribosomal protein L11 | -0.032024 |
| RPS16 | ribosomal protein S16 | -0.0315624 |
| RPL5 | ribosomal protein L5 | -0.0312821 |
| FAM162A | family with sequence similarity 162, member A | -0.0308816 |
| RPL26 | ribosomal protein L26 | -0.0299252 |
| MKLN1 | muskelin 1, intracellular mediator containing kelch motifs | -0.0293338 |
| RPL36A | ribosomal protein L36a | -0.0292542 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0291593 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | -0.0284797 |
| LDHA | lactate dehydrogenase A | -0.0277408 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0275596 |
| S100A10 | S100 calcium binding protein A10 | -0.0272531 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0270925 |
| ARID4B | AT rich interactive domain 4B (RBP1-like) | -0.0269965 |
| NAMPT | nicotinamide phosphoribosyltransferase | -0.0268417 |
| RPS20 | ribosomal protein S20 | -0.0263024 |
| GNAS | GNAS complex locus | -0.0260452 |
| LCORL | ligand dependent nuclear receptor corepressor-like | -0.0251302 |
| NAA15 | N(alpha)-acetyltransferase 15, NatA auxiliary subunit | -0.0247377 |
| RACK1 | receptor for activated C kinase 1 | -0.0242249 |
| RPL30 | ribosomal protein L30 | -0.0240465 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0236788 |
| HMGA1 | high mobility group AT-hook 1 | -0.0227805 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | -0.022563 |
| NOP58 | NOP58 ribonucleoprotein | -0.0225546 |
| RTN3 | reticulon 3 | -0.0224267 |
| TCF12 | transcription factor 12 | -0.0223121 |
| ATP1B3 | ATPase, Na+/K+ transporting, beta 3 polypeptide | -0.0222904 |
| ZNF207 | zinc finger protein 207 | -0.0222452 |
| RPL28 | ribosomal protein L28 | -0.0219395 |
| RPS29 | ribosomal protein S29 | -0.0218425 |
| HP1BP3 | heterochromatin protein 1, binding protein 3 | -0.0217851 |
| DSTN | destrin (actin depolymerizing factor) | -0.0217245 |
| SERPINB1 | serpin peptidase inhibitor, clade B (ovalbumin), member 1 | -0.0214221 |
| ATF4 | activating transcription factor 4 | -0.0213392 |
| TXNRD1 | thioredoxin reductase 1 | -0.0212733 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0212074 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0211455 |
| RPL7 | ribosomal protein L7 | -0.0210674 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0209776 |
| RPL17-C18ORF32 | RPL17-C18orf32 readthrough | -0.0208032 |
| NT5C2 | 5'-nucleotidase, cytosolic II | -0.0207479 |
| EML4 | echinoderm microtubule associated protein like 4 | -0.0207219 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | -0.0206341 |
| TNRC6B | trinucleotide repeat containing 6B | -0.0203515 |
| RPS5 | ribosomal protein S5 | -0.0203497 |
| RSL1D1 | ribosomal L1 domain containing 1 | -0.0200848 |
| RPS28 | ribosomal protein S28 | -0.0199518 |
| USP34 | ubiquitin specific peptidase 34 | -0.0199168 |
| RLF | rearranged L-myc fusion | -0.0199052 |
| HMGB1 | high mobility group box 1 | -0.0198736 |
| FTL | ferritin, light polypeptide | -0.0196588 |
| RHOA | ras homolog family member A | -0.0196148 |
| TMSB10 | thymosin beta 10 | -0.0195076 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.019495 |
| GNL3 | guanine nucleotide binding protein-like 3 (nucleolar) | -0.0194608 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0193824 |
