| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in SNU-423 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_SNU-423 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| FTH1 | ferritin, heavy polypeptide 1 | 0.266324 |
| FN1 | fibronectin 1 | 0.156453 |
| ADM | adrenomedullin | 0.140099 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.131754 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.117719 |
| COL6A3 | collagen, type VI, alpha 3 | 0.104072 |
| TMSB4X | thymosin beta 4, X-linked | 0.096858 |
| VEGFA | vascular endothelial growth factor A | 0.0929443 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0883008 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0825564 |
| SMAD3 | SMAD family member 3 | 0.0806838 |
| SDC4 | syndecan 4 | 0.0787226 |
| NAV2 | neuron navigator 2 | 0.0758812 |
| OGA | O-GlcNAcase | 0.0676607 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0651914 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0632692 |
| PPARD | peroxisome proliferator-activated receptor delta | 0.0512832 |
| FLNB | filamin B, beta | 0.0499758 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0496206 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0489594 |
| FLNA | filamin A, alpha | 0.0485593 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0470145 |
| RPL7A | ribosomal protein L7a | 0.0460647 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | 0.0445427 |
| SFTPA2 | surfactant protein A2 | 0.0445267 |
| HLA-C | major histocompatibility complex, class I, C | 0.0437243 |
| HLA-B | major histocompatibility complex, class I, B | 0.0436311 |
| MKI67 | marker of proliferation Ki-67 | 0.0428788 |
| CEP250 | centrosomal protein 250kDa | 0.042484 |
| APP | amyloid beta (A4) precursor protein | 0.0406753 |
| ARRDC3 | arrestin domain containing 3 | 0.0402205 |
| FMNL2 | formin-like 2 | 0.0392651 |
| MLPH | melanophilin | 0.0374193 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0366021 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.036471 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0363197 |
| LOXL2 | lysyl oxidase-like 2 | 0.0360411 |
| RB1CC1 | RB1-inducible coiled-coil 1 | 0.0358893 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0352723 |
| AHNAK | AHNAK nucleoprotein | 0.0342618 |
| WTAP | Wilms tumor 1 associated protein | 0.032687 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0324235 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0322972 |
| CTSB | cathepsin B | 0.0322051 |
| RPL4 | ribosomal protein L4 | 0.0319822 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0310226 |
| ANXA2 | annexin A2 | 0.0307635 |
| SPAG9 | sperm associated antigen 9 | 0.0306771 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0291732 |
| COL4A2 | collagen, type IV, alpha 2 | 0.0285973 |
| DENND5A | DENN/MADD domain containing 5A | 0.028216 |
| WSB1 | WD repeat and SOCS box containing 1 | 0.0280066 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0272069 |
| PHLDB2 | pleckstrin homology-like domain, family B, member 2 | 0.0271541 |
| PPFIA4 | protein tyrosine phosphatase, receptor type, f polypeptide (PTPRF), interacting protein (liprin), alpha 4 | 0.0269679 |
| FNIP1 | folliculin interacting protein 1 | 0.0261238 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0260432 |
| SETD5 | SET domain containing 5 | 0.0259547 |
| EIF3D | eukaryotic translation initiation factor 3, subunit D | 0.0259276 |
| AMPD3 | adenosine monophosphate deaminase 3 | 0.0257116 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.025237 |
| PTMA | prothymosin, alpha | 0.0250501 |
| KIRREL1 | kirre like nephrin family adhesion molecule 1 | 0.0247797 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.0246749 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0246619 |
| MICAL2 | microtubule associated monooxygenase, calponin and LIM domain containing 2 | 0.024525 |
| RAP1B | RAP1B, member of RAS oncogene family | 0.0244604 |
| SPSB1 | splA/ryanodine receptor domain and SOCS box containing 1 | 0.0244024 |
| THOC2 | THO complex 2 | 0.0241228 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.0239699 |
| DAB2 | Dab, mitogen-responsive phosphoprotein, homolog 2 (Drosophila) | 0.0239605 |
| ATP2B4 | ATPase, Ca++ transporting, plasma membrane 4 | 0.0238755 |
| KDM3A | lysine (K)-specific demethylase 3A | 0.0235573 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0235269 |
| ANLN | anillin, actin binding protein | 0.0235135 |
| EIF1 | eukaryotic translation initiation factor 1 | 0.0234614 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0234546 |
| CLTC | clathrin, heavy chain (Hc) | 0.0232335 |
| THRAP3 | thyroid hormone receptor associated protein 3 | 0.0230633 |
| ANKRD36B | ankyrin repeat domain 36B | 0.0230247 |
| KYNU | kynureninase | 0.0229278 |
| NT5C2 | 5'-nucleotidase, cytosolic II | 0.0228259 |
| PRELID2 | PRELI domain containing 2 | 0.0227623 |
| WWTR1 | WW domain containing transcription regulator 1 | 0.0225646 |
| IGF2R | insulin-like growth factor 2 receptor | 0.022526 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0223939 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.022387 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0222447 |
| BASP1 | brain abundant, membrane attached signal protein 1 | 0.0221474 |
| EIF2S3 | eukaryotic translation initiation factor 2, subunit 3 gamma, 52kDa | 0.0220828 |
| ACTG1 | actin gamma 1 | 0.022015 |
| SF3A1 | splicing factor 3a, subunit 1, 120kDa | 0.0218506 |
| ATP13A3 | ATPase type 13A3 | 0.0218395 |
| NGLY1 | N-glycanase 1 | 0.0217711 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0216877 |
| SFXN3 | sideroflexin 3 | 0.0214071 |
| ANKRD36 | ankyrin repeat domain 36 | 0.0213745 |
| TUBB | tubulin, beta class I | 0.0212308 |
| GFPT2 | glutamine-fructose-6-phosphate transaminase 2 | 0.0210747 |
| NPEPPS | aminopeptidase puromycin sensitive | 0.0209353 |
| Symbol | Name | Standardized Value |
|---|---|---|
| VIM | vimentin | -0.126535 |
| IQCJ-SCHIP1 | IQCJ-SCHIP1 readthrough | -0.114938 |
| GLIS3 | GLIS family zinc finger 3 | -0.0815741 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | -0.0765564 |
| VCAN | versican | -0.0729195 |
| ENO1 | enolase 1, (alpha) | -0.0688314 |
| VCL | vinculin | -0.068557 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0678756 |
| LDHA | lactate dehydrogenase A | -0.0647234 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0632229 |
| BICC1 | BicC family RNA binding protein 1 | -0.0628703 |
| EGR1 | early growth response 1 | -0.0594136 |
| DST | dystonin | -0.0565245 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0560229 |
| TPM1 | tropomyosin 1 (alpha) | -0.0559968 |
| CTSD | cathepsin D | -0.0558415 |
| HMGA2 | high mobility group AT-hook 2 | -0.0557748 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0537016 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.053484 |
| FRMD4A | FERM domain containing 4A | -0.052978 |
| FTL | ferritin, light polypeptide | -0.0527972 |
| MAGI2 | membrane associated guanylate kinase, WW and PDZ domain containing 2 | -0.0522885 |
| PLIN2 | perilipin 2 | -0.0513568 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0498788 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0492908 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0473409 |
| IER3 | immediate early response 3 | -0.0469512 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0459036 |
| LAMP2 | lysosomal-associated membrane protein 2 | -0.0449642 |
| TAPBP | TAP binding protein (tapasin) | -0.0448861 |
| GPC6 | glypican 6 | -0.0436871 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0436761 |
| RAI14 | retinoic acid induced 14 | -0.0436023 |
| ASPH | aspartate beta-hydroxylase | -0.0432481 |
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.0418878 |
| HMGA1 | high mobility group AT-hook 1 | -0.0416552 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | -0.040145 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0391617 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0390911 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | -0.0384193 |
| DIAPH2 | diaphanous-related formin 2 | -0.0383499 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0383391 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | -0.038334 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0372081 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.037005 |
| SFRP1 | secreted frizzled-related protein 1 | -0.0369503 |
| EDIL3 | EGF-like repeats and discoidin I-like domains 3 | -0.0368473 |
| PKM | pyruvate kinase, muscle | -0.0360224 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0358554 |
| NDRG1 | N-myc downstream regulated 1 | -0.0349539 |
| POTEF | POTE ankyrin domain family, member F | -0.0346862 |
| RAD51B | RAD51 paralog B | -0.0343452 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.033773 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0337627 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0334321 |
| CDH13 | cadherin 13 | -0.0332298 |
| UBE2E2 | ubiquitin-conjugating enzyme E2E 2 | -0.032768 |
| ARF4 | ADP-ribosylation factor 4 | -0.0322993 |
| CITED2 | Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 | -0.0320821 |
| CALD1 | caldesmon 1 | -0.0318828 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0318418 |
| C6ORF62 | chromosome 6 open reading frame 62 | -0.0317961 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.031507 |
| CADM1 | cell adhesion molecule 1 | -0.0313708 |
| SQSTM1 | sequestosome 1 | -0.030841 |
| ZNF292 | zinc finger protein 292 | -0.0304424 |
| QKI | QKI, KH domain containing, RNA binding | -0.0298437 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0294202 |
| RPS6 | ribosomal protein S6 | -0.029165 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0288863 |
| SOX5 | SRY (sex determining region Y)-box 5 | -0.0287645 |
| TPM4 | tropomyosin 4 | -0.02829 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0282804 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.02818 |
| TXNRD1 | thioredoxin reductase 1 | -0.0281732 |
| ANKS1B | ankyrin repeat and sterile alpha motif domain containing 1B | -0.0281115 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0280967 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.02789 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.027825 |
| GLIPR1 | GLI pathogenesis-related 1 | -0.027823 |
| AUTS2 | autism susceptibility candidate 2 | -0.0278176 |
| MX1 | MX dynamin-like GTPase 1 | -0.027022 |
| DSTN | destrin (actin depolymerizing factor) | -0.0268901 |
| RIGI | RNA sensor RIG-I | -0.0268079 |
| LPP | LIM domain containing preferred translocation partner in lipoma | -0.0267281 |
| HLA-E | major histocompatibility complex, class I, E | -0.0265495 |
| ARID1B | AT rich interactive domain 1B (SWI1-like) | -0.0265428 |
| EXOC4 | exocyst complex component 4 | -0.0263931 |
| SLC35F3 | solute carrier family 35, member F3 | -0.025866 |
| CANX | calnexin | -0.0247562 |
| UTRN | utrophin | -0.0246519 |
| PFN1 | profilin 1 | -0.0245803 |
| TENM2 | teneurin transmembrane protein 2 | -0.0245635 |
| IARS1 | isoleucyl-tRNA synthetase 1 | -0.0245366 |
| SDK1 | sidekick cell adhesion molecule 1 | -0.0242346 |
| TMSB10 | thymosin beta 10 | -0.0241406 |
| PRR16 | proline rich 16 | -0.0241014 |
| COL1A2 | collagen, type I, alpha 2 | -0.0240144 |
| HSPD1 | heat shock 60kDa protein 1 (chaperonin) | -0.02391 |
| TMEM132D | transmembrane protein 132D | -0.0236892 |
