| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in SW 1088 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_SW 1088 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| COL6A3 | collagen, type VI, alpha 3 | 0.431324 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.180076 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.105962 |
| MT2A | metallothionein 2A | 0.0913388 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0904638 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0811407 |
| SDC4 | syndecan 4 | 0.0791162 |
| MT1X | metallothionein 1X | 0.0741734 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | 0.0734941 |
| NAMPT | nicotinamide phosphoribosyltransferase | 0.0702919 |
| CALR | calreticulin | 0.0690524 |
| ADM | adrenomedullin | 0.0674456 |
| FAM13A | family with sequence similarity 13, member A | 0.0590213 |
| ARRDC3 | arrestin domain containing 3 | 0.0576485 |
| HYCC1 | hyccin PI4KA lipid kinase complex subunit 1 | 0.0535282 |
| SERPINE1 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1 | 0.0531647 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0492902 |
| ATP13A3 | ATPase type 13A3 | 0.0492269 |
| SMAD3 | SMAD family member 3 | 0.0491475 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0484119 |
| COL6A2 | collagen, type VI, alpha 2 | 0.0467373 |
| ANLN | anillin, actin binding protein | 0.0445921 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.0439753 |
| TMSB4X | thymosin beta 4, X-linked | 0.0415829 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0413931 |
| ITGA3 | integrin, alpha 3 (antigen CD49C, alpha 3 subunit of VLA-3 receptor) | 0.0405423 |
| ITGA5 | integrin, alpha 5 (fibronectin receptor, alpha polypeptide) | 0.0396952 |
| DDIT4 | DNA-damage-inducible transcript 4 | 0.0382322 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.037039 |
| ZNF292 | zinc finger protein 292 | 0.0368611 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | 0.0368305 |
| UGCG | UDP-glucose ceramide glucosyltransferase | 0.0359018 |
| MARCHF6 | membrane associated ring-CH-type finger 6 | 0.0349016 |
| VEGFA | vascular endothelial growth factor A | 0.0338845 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0337616 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0335932 |
| ETS1 | v-ets avian erythroblastosis virus E26 oncogene homolog 1 | 0.0319843 |
| C1D | C1D nuclear receptor corepressor | 0.0315337 |
| HLA-C | major histocompatibility complex, class I, C | 0.0310738 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0302362 |
| APP | amyloid beta (A4) precursor protein | 0.0302315 |
| TMED9 | transmembrane emp24 protein transport domain containing 9 | 0.0301273 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | 0.0300553 |
| COG5 | component of oligomeric golgi complex 5 | 0.0296877 |
| B2M | beta-2-microglobulin | 0.0288991 |
| RAB8B | RAB8B, member RAS oncogene family | 0.0288822 |
| RNF145 | ring finger protein 145 | 0.0287727 |
| NDRG1 | N-myc downstream regulated 1 | 0.0284907 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0281343 |
| RSRC2 | arginine/serine-rich coiled-coil 2 | 0.0278267 |
| BACE2 | beta-site APP-cleaving enzyme 2 | 0.0274582 |
| L1CAM | L1 cell adhesion molecule | 0.027457 |
| YWHAQ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, theta | 0.027262 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0271658 |
| SUCO | SUN domain containing ossification factor | 0.026737 |
| FLNA | filamin A, alpha | 0.0259908 |
| SMTN | smoothelin | 0.0258079 |
| PLAUR | plasminogen activator, urokinase receptor | 0.0256327 |
| SRRM2 | serine/arginine repetitive matrix 2 | 0.0251413 |
| COPA | coatomer protein complex, subunit alpha | 0.0246992 |
| GARS1 | glycyl-tRNA synthetase 1 | 0.0246182 |
| RAD23B | RAD23 homolog B (S. cerevisiae) | 0.0244533 |
| CAVIN1 | caveolae associated protein 1 | 0.0243816 |
| COL6A1 | collagen, type VI, alpha 1 | 0.0243539 |
| RNMT | RNA (guanine-7-) methyltransferase | 0.0240624 |
| TBC1D23 | TBC1 domain family, member 23 | 0.0240011 |
| FRMD6 | FERM domain containing 6 | 0.0239105 |
| LUC7L2 | LUC7-like 2 (S. cerevisiae) | 0.0233924 |
| PLEC | plectin | 0.0230712 |
| XPO6 | exportin 6 | 0.0229499 |
| TFG | TRK-fused gene | 0.0229052 |
| XPO1 | exportin 1 | 0.022772 |
| TPR | translocated promoter region, nuclear basket protein | 0.0227702 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0226003 |
| MSN | moesin | 0.0225466 |
| SETD5 | SET domain containing 5 | 0.0224599 |
| RPL3 | ribosomal protein L3 | 0.0223918 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0220547 |
| ITPR3 | inositol 1,4,5-trisphosphate receptor, type 3 | 0.022007 |
| ARHGAP35 | Rho GTPase activating protein 35 | 0.0218798 |
| MAP2K1 | mitogen-activated protein kinase kinase 1 | 0.0218302 |
| NFKBIA | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha | 0.0216037 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.021512 |
| ZNF160 | zinc finger protein 160 | 0.0215 |
| KLF7 | Kruppel-like factor 7 (ubiquitous) | 0.0214434 |
| UBA6 | ubiquitin-like modifier activating enzyme 6 | 0.0213306 |
| TENT2 | terminal nucleotidyltransferase 2 | 0.0211003 |
| TNIP1 | TNFAIP3 interacting protein 1 | 0.0210923 |
| MATR3 | matrin 3 | 0.0207374 |
| PPP1R18 | protein phosphatase 1, regulatory subunit 18 | 0.020696 |
| AHDC1 | AT hook, DNA binding motif, containing 1 | 0.0206142 |
| PRRC1 | proline-rich coiled-coil 1 | 0.0206101 |
| WDFY2 | WD repeat and FYVE domain containing 2 | 0.0205481 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0204119 |
| NAV2 | neuron navigator 2 | 0.0204039 |
| EMP1 | epithelial membrane protein 1 | 0.0203519 |
| APOL2 | apolipoprotein L, 2 | 0.0203335 |
| CCNL1 | cyclin L1 | 0.020333 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0202945 |
| ZMIZ1 | zinc finger, MIZ-type containing 1 | 0.0202889 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.198566 |
| VIM | vimentin | -0.161791 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.125872 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.11703 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.10604 |
| TGFBI | transforming growth factor, beta-induced, 68kDa | -0.103882 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0893707 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0755058 |
| FTL | ferritin, light polypeptide | -0.0646007 |
| FN1 | fibronectin 1 | -0.0614375 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.0583102 |
| VCL | vinculin | -0.0559623 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0556275 |
| ENO1 | enolase 1, (alpha) | -0.0555404 |
| SEMA5A | sema domain, seven thrombospondin repeats (type 1 and type 1-like), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 5A | -0.054904 |
| TMSB10 | thymosin beta 10 | -0.0547267 |
| RPL34 | ribosomal protein L34 | -0.0544921 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0531122 |
| TMEM158 | transmembrane protein 158 (gene/pseudogene) | -0.0521331 |
| RPL35A | ribosomal protein L35a | -0.0498247 |
| IL6 | interleukin 6 | -0.0476387 |
| POTEF | POTE ankyrin domain family, member F | -0.0463673 |
| TPM4 | tropomyosin 4 | -0.0455122 |
| TPT1 | tumor protein, translationally-controlled 1 | -0.044907 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | -0.0442993 |
| ACTG1 | actin gamma 1 | -0.0442175 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0441464 |
| RPLP1 | ribosomal protein, large, P1 | -0.0439393 |
| F3 | coagulation factor III (thromboplastin, tissue factor) | -0.0429612 |
| PRSS23 | protease, serine, 23 | -0.0422812 |
| KYNU | kynureninase | -0.0419091 |
| ERC2 | ELKS/RAB6-interacting/CAST family member 2 | -0.0416799 |
| EGFR | epidermal growth factor receptor | -0.0412943 |
| KTN1 | kinectin 1 (kinesin receptor) | -0.0409292 |
| RPS8 | ribosomal protein S8 | -0.0409003 |
| CANX | calnexin | -0.0407563 |
| COL1A1 | collagen, type I, alpha 1 | -0.0402854 |
| RPS6 | ribosomal protein S6 | -0.0397878 |
| ASPH | aspartate beta-hydroxylase | -0.0395525 |
| SEPTIN7 | septin 7 | -0.0394387 |
| TNS3 | tensin 3 | -0.0391278 |
| HM13 | histocompatibility (minor) 13 | -0.0383835 |
| RAD51B | RAD51 paralog B | -0.0379544 |
| CALD1 | caldesmon 1 | -0.0370716 |
| CHD9 | chromodomain helicase DNA binding protein 9 | -0.0362425 |
| EXT1 | exostosin glycosyltransferase 1 | -0.0361581 |
| ROBO1 | roundabout, axon guidance receptor, homolog 1 (Drosophila) | -0.0356629 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0355259 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0354583 |
| NAV1 | neuron navigator 1 | -0.0353733 |
| KMT2C | lysine (K)-specific methyltransferase 2C | -0.0349783 |
| NR3C1 | nuclear receptor subfamily 3, group C, member 1 (glucocorticoid receptor) | -0.034556 |
| INTS6 | integrator complex subunit 6 | -0.0336044 |
| PKM | pyruvate kinase, muscle | -0.0334748 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0333373 |
| ATXN1 | ataxin 1 | -0.0330859 |
| CDH13 | cadherin 13 | -0.0327296 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | -0.0325817 |
| HMGA2 | high mobility group AT-hook 2 | -0.0317202 |
| IGFBP5 | insulin-like growth factor binding protein 5 | -0.031563 |
| RPL38 | ribosomal protein L38 | -0.0314261 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | -0.0313357 |
| PRELID2 | PRELI domain containing 2 | -0.0307278 |
| RPS3 | ribosomal protein S3 | -0.0306814 |
| RPL31 | ribosomal protein L31 | -0.0305437 |
| FBXO11 | F-box protein 11 | -0.0301173 |
| DNAH11 | dynein, axonemal, heavy chain 11 | -0.0300926 |
| LOX | lysyl oxidase | -0.0299954 |
| PTMA | prothymosin, alpha | -0.0297549 |
| BPTF | bromodomain PHD finger transcription factor | -0.029415 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.028949 |
| ATRX | alpha thalassemia/mental retardation syndrome X-linked | -0.0287942 |
| TFPI2 | tissue factor pathway inhibitor 2 | -0.028749 |
| TANC2 | tetratricopeptide repeat, ankyrin repeat and coiled-coil containing 2 | -0.0286252 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0284145 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | -0.0279072 |
| RPS12 | ribosomal protein S12 | -0.0277357 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275355 |
| DSTN | destrin (actin depolymerizing factor) | -0.0274456 |
| EIF1 | eukaryotic translation initiation factor 1 | -0.0273785 |
| PDIA3 | protein disulfide isomerase family A, member 3 | -0.0267276 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0265417 |
| RPS27A | ribosomal protein S27a | -0.0263602 |
| GNB1 | guanine nucleotide binding protein (G protein), beta polypeptide 1 | -0.0262835 |
| PRKCA | protein kinase C, alpha | -0.0255988 |
| ANKRD28 | ankyrin repeat domain 28 | -0.0255273 |
| GRB10 | growth factor receptor-bound protein 10 | -0.0255152 |
| CADM1 | cell adhesion molecule 1 | -0.0255125 |
| FNDC3B | fibronectin type III domain containing 3B | -0.0255092 |
| RPS11 | ribosomal protein S11 | -0.025504 |
| SEC24D | SEC24 family member D | -0.025403 |
| ITGAV | integrin, alpha V | -0.0252477 |
| MXI1 | MAX interactor 1, dimerization protein | -0.02515 |
| SEC31A | SEC31 homolog A (S. cerevisiae) | -0.0251313 |
| RPS14 | ribosomal protein S14 | -0.0249107 |
| NRP1 | neuropilin 1 | -0.0247565 |
| HDAC8 | histone deacetylase 8 | -0.0246098 |
| CYP1B1 | cytochrome P450, family 1, subfamily B, polypeptide 1 | -0.0243631 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | -0.0243309 |
| TPM1 | tropomyosin 1 (alpha) | -0.024165 |
