| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Delamanid perturbation in SW 1271 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Delamanid_SW 1271 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| DSCAM | Down syndrome cell adhesion molecule | 0.108348 |
| FTH1 | ferritin, heavy polypeptide 1 | 0.10444 |
| EEF2 | eukaryotic translation elongation factor 2 | 0.101322 |
| IGFBP3 | insulin-like growth factor binding protein 3 | 0.0885301 |
| CALR | calreticulin | 0.0864465 |
| CEP250 | centrosomal protein 250kDa | 0.0815724 |
| ADM | adrenomedullin | 0.0806005 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0735346 |
| WAC | WW domain containing adaptor with coiled-coil | 0.0729315 |
| BHLHE40 | basic helix-loop-helix family, member e40 | 0.0711722 |
| SETD5 | SET domain containing 5 | 0.0699629 |
| CD44 | CD44 molecule (Indian blood group) | 0.0605349 |
| SDC4 | syndecan 4 | 0.0604814 |
| TAF1D | TATA box binding protein (TBP)-associated factor, RNA polymerase I, D, 41kDa | 0.0596224 |
| SREK1 | splicing regulatory glutamine/lysine-rich protein 1 | 0.0594677 |
| UBR5 | ubiquitin protein ligase E3 component n-recognin 5 | 0.0581211 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0565511 |
| SEC23A | Sec23 homolog A (S. cerevisiae) | 0.0563896 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | 0.0561555 |
| SF3B1 | splicing factor 3b, subunit 1, 155kDa | 0.0549428 |
| RAB6A | RAB6A, member RAS oncogene family | 0.0548753 |
| CLTC | clathrin, heavy chain (Hc) | 0.0540877 |
| SLC2A3 | solute carrier family 2 (facilitated glucose transporter), member 3 | 0.0540715 |
| CPNE1 | copine I | 0.0528076 |
| FMNL2 | formin-like 2 | 0.0517602 |
| RPL4 | ribosomal protein L4 | 0.0509412 |
| NPM1 | nucleophosmin (nucleolar phosphoprotein B23, numatrin) | 0.0498926 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0496804 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0486703 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0485867 |
| CLINT1 | clathrin interactor 1 | 0.0485281 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0484576 |
| NUP58 | nucleoporin 58 | 0.0481084 |
| PPP6R3 | protein phosphatase 6, regulatory subunit 3 | 0.0480175 |
| HOOK2 | hook microtubule-tethering protein 2 | 0.047186 |
| NIPBL | Nipped-B homolog (Drosophila) | 0.0465387 |
| KTN1 | kinectin 1 (kinesin receptor) | 0.04636 |
| FLNA | filamin A, alpha | 0.0463527 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0457447 |
| RACGAP1 | Rac GTPase activating protein 1 | 0.0457388 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0444994 |
| RBM39 | RNA binding motif protein 39 | 0.0431888 |
| NCAPD2 | non-SMC condensin I complex, subunit D2 | 0.0431242 |
| CCNL1 | cyclin L1 | 0.0425203 |
| FUS | FUS RNA binding protein | 0.0414541 |
| RPL7A | ribosomal protein L7a | 0.0413779 |
| ANXA2 | annexin A2 | 0.0413112 |
| ZC3H13 | zinc finger CCCH-type containing 13 | 0.040581 |
| YAP1 | Yes-associated protein 1 | 0.0405735 |
| LRRFIP1 | leucine rich repeat (in FLII) interacting protein 1 | 0.0402048 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.040062 |
| DLGAP4 | discs, large (Drosophila) homolog-associated protein 4 | 0.0397289 |
| SMAD3 | SMAD family member 3 | 0.0395635 |
| USP15 | ubiquitin specific peptidase 15 | 0.0394869 |
| ASXL1 | additional sex combs like transcriptional regulator 1 | 0.0387379 |
| FAM193A | family with sequence similarity 193, member A | 0.0386842 |
| CAPRIN2 | caprin family member 2 | 0.038361 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0373086 |
| AP2B1 | adaptor-related protein complex 2, beta 1 subunit | 0.0371717 |
| BIRC6 | baculoviral IAP repeat containing 6 | 0.0371493 |
| ECT2 | epithelial cell transforming 2 | 0.0370854 |
| PTMA | prothymosin, alpha | 0.0370642 |
| TRPC4AP | transient receptor potential cation channel, subfamily C, member 4 associated protein | 0.0367808 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0362149 |
| EIF4B | eukaryotic translation initiation factor 4B | 0.0360432 |
| SPAG9 | sperm associated antigen 9 | 0.0358866 |
| PSME4 | proteasome (prosome, macropain) activator subunit 4 | 0.035738 |
| FXR1 | fragile X mental retardation, autosomal homolog 1 | 0.0356959 |
| YBX3 | Y box binding protein 3 | 0.0354772 |
| RANBP2 | RAN binding protein 2 | 0.0347691 |
| ADAM17 | ADAM metallopeptidase domain 17 | 0.0345421 |
| ITSN2 | intersectin 2 | 0.0344728 |
| ACTG1 | actin gamma 1 | 0.0344623 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0344555 |
| ERBIN | erbb2 interacting protein | 0.0340761 |
| TOP2B | topoisomerase (DNA) II beta 180kDa | 0.0340543 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0340415 |
| RAB5A | RAB5A, member RAS oncogene family | 0.0339318 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | 0.033778 |
| APP | amyloid beta (A4) precursor protein | 0.0337071 |
| YBX1 | Y box binding protein 1 | 0.0336911 |
| NUMA1 | nuclear mitotic apparatus protein 1 | 0.0336272 |
| DGKD | diacylglycerol kinase, delta 130kDa | 0.0336061 |
| UBR4 | ubiquitin protein ligase E3 component n-recognin 4 | 0.0333313 |
| EGFR | epidermal growth factor receptor | 0.0333135 |
| ERC1 | ELKS/RAB6-interacting/CAST family member 1 | 0.0331794 |
| BCLAF1 | BCL2-associated transcription factor 1 | 0.0330833 |
| HDLBP | high density lipoprotein binding protein | 0.0330474 |
| NGLY1 | N-glycanase 1 | 0.0328462 |
| ELP2 | elongator acetyltransferase complex subunit 2 | 0.0328442 |
| LRRFIP2 | leucine rich repeat (in FLII) interacting protein 2 | 0.0328133 |
| SAMD4A | sterile alpha motif domain containing 4A | 0.032368 |
| GOLGA4 | golgin A4 | 0.0321781 |
| EIF4H | eukaryotic translation initiation factor 4H | 0.0321548 |
| STAT3 | signal transducer and activator of transcription 3 (acute-phase response factor) | 0.0319507 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0318711 |
| CYTH1 | cytohesin 1 | 0.0315215 |
| DERA | deoxyribose-phosphate aldolase (putative) | 0.0311734 |
| CANX | calnexin | 0.0310447 |
| SOD2 | superoxide dismutase 2, mitochondrial | 0.0309802 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.156795 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | -0.0499858 |
| RPLP1 | ribosomal protein, large, P1 | -0.0487955 |
| ZNF292 | zinc finger protein 292 | -0.0479032 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | -0.0422226 |
| RPL30 | ribosomal protein L30 | -0.041559 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0412274 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | -0.0405472 |
| CALM1 | calmodulin 1 (phosphorylase kinase, delta) | -0.0394538 |
| EXOC4 | exocyst complex component 4 | -0.0379961 |
| NFE2L2 | nuclear factor, erythroid 2-like 2 | -0.0363745 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | -0.0340127 |
| TAS2R14 | taste receptor, type 2, member 14 | -0.0336857 |
| BCAS3 | breast carcinoma amplified sequence 3 | -0.0335827 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.03303 |
| RPL27A | ribosomal protein L27a | -0.0324511 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0322802 |
| RPL35A | ribosomal protein L35a | -0.0320891 |
| WNK1 | WNK lysine deficient protein kinase 1 | -0.0320469 |
| XRN1 | 5'-3' exoribonuclease 1 | -0.031364 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | -0.0311138 |
| ERCC6L2 | excision repair cross-complementation group 6-like 2 | -0.030776 |
| PRH1 | proline-rich protein HaeIII subfamily 1 | -0.0305341 |
| FBXL7 | F-box and leucine-rich repeat protein 7 | -0.0298284 |
| ATG10 | autophagy related 10 | -0.0297163 |
| SMYD3 | SET and MYND domain containing 3 | -0.0296328 |
| EFNA5 | ephrin-A5 | -0.0292265 |
| APOLD1 | apolipoprotein L domain containing 1 | -0.0290663 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | -0.0280544 |
| RIN2 | Ras and Rab interactor 2 | -0.028016 |
| RPS28 | ribosomal protein S28 | -0.0276343 |
| PGK1 | phosphoglycerate kinase 1 | -0.0275835 |
| ZBTB38 | zinc finger and BTB domain containing 38 | -0.0275614 |
| ZC3H12B | zinc finger CCCH-type containing 12B | -0.0275381 |
| USP34 | ubiquitin specific peptidase 34 | -0.027258 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0270907 |
| HMGA2 | high mobility group AT-hook 2 | -0.0269741 |
| THSD4 | thrombospondin, type I, domain containing 4 | -0.0269026 |
| BRIP1 | BRCA1 interacting protein C-terminal helicase 1 | -0.0268532 |
| HMGB1 | high mobility group box 1 | -0.0266587 |
| WDR70 | WD repeat domain 70 | -0.0266176 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0266136 |
| ENO1 | enolase 1, (alpha) | -0.0265019 |
| VIM | vimentin | -0.0262201 |
| DSTN | destrin (actin depolymerizing factor) | -0.0258881 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0257683 |
| BCKDHB | branched chain keto acid dehydrogenase E1, beta polypeptide | -0.0257371 |
| NALCN | sodium leak channel, non selective | -0.0251444 |
| DEK | DEK proto-oncogene | -0.0251116 |
| TRA2B | transformer 2 beta homolog (Drosophila) | -0.0247732 |
| EGR1 | early growth response 1 | -0.0247709 |
| AKAP9 | A kinase (PRKA) anchor protein 9 | -0.0245423 |
| TUBA1B | tubulin, alpha 1b | -0.0245053 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0242761 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | -0.0241683 |
| FBXL17 | F-box and leucine-rich repeat protein 17 | -0.0241642 |
| SNX14 | sorting nexin 14 | -0.024161 |
| RPS13 | ribosomal protein S13 | -0.0239967 |
| VCL | vinculin | -0.0239631 |
| CCNH | cyclin H | -0.0237753 |
| RPL15 | ribosomal protein L15 | -0.023322 |
| MT2A | metallothionein 2A | -0.0233034 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.0232421 |
| BPTF | bromodomain PHD finger transcription factor | -0.0231021 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0229412 |
| BICD1 | bicaudal D homolog 1 (Drosophila) | -0.0228882 |
| RPL37 | ribosomal protein L37 | -0.0228366 |
| MBD5 | methyl-CpG binding domain protein 5 | -0.0228181 |
| CKAP2 | cytoskeleton associated protein 2 | -0.0226439 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0226416 |
| CKAP2L | cytoskeleton associated protein 2-like | -0.0224131 |
| KLHL5 | kelch-like family member 5 | -0.0221672 |
| MPP2 | membrane protein, palmitoylated 2 (MAGUK p55 subfamily member 2) | -0.0221671 |
| NBEA | neurobeachin | -0.0221193 |
| SLC30A7 | solute carrier family 30 (zinc transporter), member 7 | -0.0216474 |
| NBEAL1 | neurobeachin-like 1 | -0.0213986 |
| WDPCP | WD repeat containing planar cell polarity effector | -0.021247 |
| RPL35 | ribosomal protein L35 | -0.0212468 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | -0.0211574 |
| INVS | inversin | -0.0211478 |
| PRKDC | protein kinase, DNA-activated, catalytic polypeptide | -0.0211469 |
| ATP11A | ATPase, class VI, type 11A | -0.0211025 |
| PBX3 | pre-B-cell leukemia homeobox 3 | -0.0210877 |
| HMMR | hyaluronan-mediated motility receptor (RHAMM) | -0.0210823 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | -0.0210777 |
| PKM | pyruvate kinase, muscle | -0.0210404 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | -0.0209925 |
| RPL36A | ribosomal protein L36a | -0.0209532 |
| LOC112694756 | uncharaterized LOC112694756 | -0.020882 |
| FRS2 | fibroblast growth factor receptor substrate 2 | -0.0207276 |
| CCND1 | cyclin D1 | -0.0206299 |
| WWOX | WW domain containing oxidoreductase | -0.0205877 |
| RACK1 | receptor for activated C kinase 1 | -0.020042 |
| EXOC6B | exocyst complex component 6B | -0.0199166 |
| IFIH1 | interferon induced with helicase C domain 1 | -0.0198878 |
| RNF111 | ring finger protein 111 | -0.0198092 |
| MYADM | myeloid-associated differentiation marker | -0.0197786 |
| PFN1 | profilin 1 | -0.0197063 |
| PRELID2 | PRELI domain containing 2 | -0.0197027 |
| PAIP2 | poly(A) binding protein interacting protein 2 | -0.0196851 |
