| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in A-172 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_A-172 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| CDH13 | cadherin 13 | 0.196472 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.124134 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.123012 |
| AHNAK | AHNAK nucleoprotein | 0.0989787 |
| ASPH | aspartate beta-hydroxylase | 0.0956466 |
| ABL2 | ABL proto-oncogene 2, non-receptor tyrosine kinase | 0.0955896 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.0921715 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0915051 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0886217 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0796889 |
| PBX3 | pre-B-cell leukemia homeobox 3 | 0.0783251 |
| DST | dystonin | 0.0743149 |
| HDAC9 | histone deacetylase 9 | 0.0709821 |
| PODXL | podocalyxin-like | 0.0709237 |
| MAP1B | microtubule-associated protein 1B | 0.0676371 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | 0.063795 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.0627026 |
| FSTL1 | follistatin-like 1 | 0.0622397 |
| PTPN14 | protein tyrosine phosphatase, non-receptor type 14 | 0.0618712 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0595014 |
| CACNA2D3 | calcium channel, voltage-dependent, alpha 2/delta subunit 3 | 0.0587407 |
| KCNQ5 | potassium channel, voltage gated KQT-like subfamily Q, member 5 | 0.0582525 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0579393 |
| ANKRD11 | ankyrin repeat domain 11 | 0.0557274 |
| EFNA5 | ephrin-A5 | 0.0555214 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.053768 |
| MAP4K4 | mitogen-activated protein kinase kinase kinase kinase 4 | 0.0531014 |
| EGFR | epidermal growth factor receptor | 0.0529609 |
| CANX | calnexin | 0.0510595 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0503382 |
| PLAT | plasminogen activator, tissue | 0.0502408 |
| CENPF | centromere protein F, 350/400kDa | 0.0484652 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0474015 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.047089 |
| SLC39A11 | solute carrier family 39, member 11 | 0.0468724 |
| IGFN1 | immunoglobulin-like and fibronectin type III domain containing 1 | 0.0467411 |
| TPM3 | tropomyosin 3 | 0.0464692 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0442891 |
| MSN | moesin | 0.04405 |
| INTS6 | integrator complex subunit 6 | 0.044024 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0438806 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0427803 |
| COL5A1 | collagen, type V, alpha 1 | 0.0410536 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | 0.0408517 |
| DGKG | diacylglycerol kinase, gamma 90kDa | 0.0406982 |
| DCLK2 | doublecortin-like kinase 2 | 0.0401696 |
| NAV2 | neuron navigator 2 | 0.0396313 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0391141 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | 0.0386162 |
| SMAD3 | SMAD family member 3 | 0.0371675 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0370718 |
| PRELID2 | PRELI domain containing 2 | 0.0370472 |
| PLXNA2 | plexin A2 | 0.036606 |
| DSPP | dentin sialophosphoprotein | 0.0365674 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0360254 |
| MYOF | myoferlin | 0.0358922 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0356525 |
| POTEF | POTE ankyrin domain family, member F | 0.0354374 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0352824 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0351357 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.034952 |
| DIAPH3 | diaphanous-related formin 3 | 0.0342182 |
| ERBIN | erbb2 interacting protein | 0.0342133 |
| FLNA | filamin A, alpha | 0.0339323 |
| RUNX1 | runt-related transcription factor 1 | 0.0332631 |
| RND3 | Rho family GTPase 3 | 0.0330422 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0329974 |
| XKR6 | XK, Kell blood group complex subunit-related family, member 6 | 0.0327997 |
| IGF2BP2 | insulin-like growth factor 2 mRNA binding protein 2 | 0.0326729 |
| ENO1 | enolase 1, (alpha) | 0.0325219 |
| TPM4 | tropomyosin 4 | 0.0324706 |
| LDHA | lactate dehydrogenase A | 0.0324462 |
| ALCAM | activated leukocyte cell adhesion molecule | 0.0322392 |
| LHFPL2 | lipoma HMGIC fusion partner-like 2 | 0.0322296 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.031996 |
| VCL | vinculin | 0.0317113 |
| CD44 | CD44 molecule (Indian blood group) | 0.0315635 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0311156 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0309808 |
| ANXA1 | annexin A1 | 0.0307553 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0305009 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0303811 |
| KIAA1549L | KIAA1549-like | 0.0301726 |
| SMC4 | structural maintenance of chromosomes 4 | 0.0299636 |
| CYTH3 | cytohesin 3 | 0.0298736 |
| PCDH7 | protocadherin 7 | 0.0298212 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0292971 |
| ITGA6 | integrin, alpha 6 | 0.028358 |
| SEPTIN9 | septin 9 | 0.0276128 |
| LIMCH1 | LIM and calponin homology domains 1 | 0.0275079 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.0274146 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0273806 |
| SEPTIN7 | septin 7 | 0.0273387 |
| KPNA4 | karyopherin alpha 4 (importin alpha 3) | 0.027093 |
| CALR | calreticulin | 0.0270483 |
| ZFAND3 | zinc finger, AN1-type domain 3 | 0.0270483 |
| RRM2 | ribonucleotide reductase M2 | 0.0267029 |
| SDCCAG8 | serologically defined colon cancer antigen 8 | 0.026362 |
| DIP2C | DIP2 disco-interacting protein 2 homolog C (Drosophila) | 0.0262285 |
| FMN2 | formin 2 | 0.0259469 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGFBP3 | insulin-like growth factor binding protein 3 | -0.243569 |
| FBN1 | fibrillin 1 | -0.149099 |
| LOX | lysyl oxidase | -0.128074 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | -0.124168 |
| VIM | vimentin | -0.114427 |
| COL1A2 | collagen, type I, alpha 2 | -0.105392 |
| HLA-B | major histocompatibility complex, class I, B | -0.085676 |
| TMSB10 | thymosin beta 10 | -0.0779041 |
| LOXL2 | lysyl oxidase-like 2 | -0.0734953 |
| THBS2 | thrombospondin 2 | -0.06783 |
| COL3A1 | collagen, type III, alpha 1 | -0.0666712 |
| ZBTB20 | zinc finger and BTB domain containing 20 | -0.0648727 |
| MEIS2 | Meis homeobox 2 | -0.0593906 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0585508 |
| UBC | ubiquitin C | -0.0544035 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0539007 |
| SOD2 | superoxide dismutase 2, mitochondrial | -0.0491504 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | -0.0467492 |
| MX2 | MX dynamin-like GTPase 2 | -0.0461487 |
| COL8A1 | collagen, type VIII, alpha 1 | -0.0432721 |
| COL5A2 | collagen, type V, alpha 2 | -0.0430381 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0428314 |
| B2M | beta-2-microglobulin | -0.0427585 |
| DPYSL3 | dihydropyrimidinase-like 3 | -0.0427163 |
| STC1 | stanniocalcin 1 | -0.0405013 |
| HLA-E | major histocompatibility complex, class I, E | -0.0401825 |
| GPC6 | glypican 6 | -0.0397545 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0379383 |
| SLC5A3 | solute carrier family 5 (sodium/myo-inositol cotransporter), member 3 | -0.0364984 |
| HLA-C | major histocompatibility complex, class I, C | -0.0363851 |
| SERPINE2 | serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 2 | -0.0347894 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0329267 |
| S100A6 | S100 calcium binding protein A6 | -0.0325062 |
| ARL4C | ADP-ribosylation factor-like 4C | -0.0312622 |
| SUCNR1 | succinate receptor 1 | -0.0302182 |
| FRMD5 | FERM domain containing 5 | -0.0302017 |
| NHS | Nance-Horan syndrome (congenital cataracts and dental anomalies) | -0.0295399 |
| CD99 | CD99 molecule | -0.0290915 |
| P4HA2 | prolyl 4-hydroxylase, alpha polypeptide II | -0.029062 |
| DIRAS3 | DIRAS family, GTP-binding RAS-like 3 | -0.0286815 |
| TMOD1 | tropomodulin 1 | -0.0286732 |
| SBF2 | SET binding factor 2 | -0.0278245 |
| ANKRD10 | ankyrin repeat domain 10 | -0.0269233 |
| WDFY1 | WD repeat and FYVE domain containing 1 | -0.0250696 |
| NPR2 | natriuretic peptide receptor 2 | -0.0245064 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0241963 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0241697 |
| KIFAP3 | kinesin-associated protein 3 | -0.024022 |
| ARL15 | ADP-ribosylation factor-like 15 | -0.0239638 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0235368 |
| MT1X | metallothionein 1X | -0.0227762 |
| MARCKS | myristoylated alanine-rich protein kinase C substrate | -0.0218741 |
| DKK3 | dickkopf WNT signaling pathway inhibitor 3 | -0.0218464 |
| AKT3 | v-akt murine thymoma viral oncogene homolog 3 | -0.02163 |
| NFKBIZ | nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, zeta | -0.0215907 |
| PXDN | peroxidasin | -0.0215461 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0214668 |
| PHLDA1 | pleckstrin homology-like domain, family A, member 1 | -0.0213234 |
| MTSS1 | metastasis suppressor 1 | -0.0213234 |
| MAP3K2 | mitogen-activated protein kinase kinase kinase 2 | -0.0208752 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0206003 |
| NDRG1 | N-myc downstream regulated 1 | -0.0203841 |
| DKK1 | dickkopf WNT signaling pathway inhibitor 1 | -0.0201722 |
| POLR2A | polymerase (RNA) II (DNA directed) polypeptide A, 220kDa | -0.0200552 |
| SPARC | secreted protein, acidic, cysteine-rich (osteonectin) | -0.0199937 |
| SH3BP5 | SH3-domain binding protein 5 (BTK-associated) | -0.0199436 |
| PRRX1 | paired related homeobox 1 | -0.0199083 |
| EPAS1 | endothelial PAS domain protein 1 | -0.0193148 |
| MXRA5 | matrix-remodelling associated 5 | -0.0192591 |
| P4HA1 | prolyl 4-hydroxylase, alpha polypeptide I | -0.0181951 |
| LRRC49 | leucine rich repeat containing 49 | -0.0178296 |
| CTSB | cathepsin B | -0.0176715 |
| SLC6A6 | solute carrier family 6 (neurotransmitter transporter), member 6 | -0.0176123 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0175798 |
| FBXL2 | F-box and leucine-rich repeat protein 2 | -0.0175357 |
| ZEB2 | zinc finger E-box binding homeobox 2 | -0.0170361 |
| ABI3BP | ABI family, member 3 (NESH) binding protein | -0.0170296 |
| BSG | basigin (Ok blood group) | -0.0170019 |
| NF1 | neurofibromin 1 | -0.016482 |
| TRIM56 | tripartite motif containing 56 | -0.0164816 |
| NIPSNAP2 | nipsnap homolog 2 | -0.0164466 |
| C1D | C1D nuclear receptor corepressor | -0.0163464 |
| IL1RAP | interleukin 1 receptor accessory protein | -0.0163193 |
| ABCC1 | ATP-binding cassette, sub-family C (CFTR/MRP), member 1 | -0.0162677 |
| SYT12 | synaptotagmin XII | -0.0162109 |
| MYO9A | myosin IXA | -0.0162085 |
| TRPM7 | transient receptor potential cation channel, subfamily M, member 7 | -0.0161723 |
| EHBP1 | EH domain binding protein 1 | -0.0161619 |
| PTMA | prothymosin, alpha | -0.0160647 |
| OGA | O-GlcNAcase | -0.0160237 |
| NDFIP1 | Nedd4 family interacting protein 1 | -0.015948 |
| WTAP | Wilms tumor 1 associated protein | -0.0159001 |
| AUTS2 | autism susceptibility candidate 2 | -0.0158929 |
| ATP13A3 | ATPase type 13A3 | -0.015886 |
| CLU | clusterin | -0.0158719 |
| VPS54 | vacuolar protein sorting 54 homolog (S. cerevisiae) | -0.0158044 |
| MT2A | metallothionein 2A | -0.0157603 |
| LINGO2 | leucine rich repeat and Ig domain containing 2 | -0.0157198 |
| IGF2R | insulin-like growth factor 2 receptor | -0.0156439 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0156432 |
