| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in CHP-212 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_CHP-212 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| VCL | vinculin | 0.200327 |
| FMN1 | formin 1 | 0.144685 |
| EXT1 | exostosin glycosyltransferase 1 | 0.106281 |
| AKAP12 | A kinase (PRKA) anchor protein 12 | 0.104075 |
| TLE4 | transducin-like enhancer of split 4 | 0.10314 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.10051 |
| THSD4 | thrombospondin, type I, domain containing 4 | 0.0839272 |
| NALF1 | NALCN channel auxiliary factor 1 | 0.0815779 |
| LSAMP | limbic system-associated membrane protein | 0.0710785 |
| PRKCA | protein kinase C, alpha | 0.0645125 |
| ANTXR1 | anthrax toxin receptor 1 | 0.0644016 |
| NPAS2 | neuronal PAS domain protein 2 | 0.0620343 |
| PDE3A | phosphodiesterase 3A, cGMP-inhibited | 0.0615586 |
| VMP1 | vacuole membrane protein 1 | 0.059445 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0576567 |
| NRG1 | neuregulin 1 | 0.0538216 |
| BCAS3 | breast carcinoma amplified sequence 3 | 0.053053 |
| BPTF | bromodomain PHD finger transcription factor | 0.0500106 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0496544 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.048987 |
| RNF213 | ring finger protein 213 | 0.0489226 |
| PITPNC1 | phosphatidylinositol transfer protein, cytoplasmic 1 | 0.048863 |
| PTPRD | protein tyrosine phosphatase, receptor type, D | 0.0470242 |
| DST | dystonin | 0.0464252 |
| PLAT | plasminogen activator, tissue | 0.0461806 |
| ATXN1 | ataxin 1 | 0.0458506 |
| GBE1 | glucan (1,4-alpha-), branching enzyme 1 | 0.0458294 |
| SLIT2 | slit homolog 2 (Drosophila) | 0.0444679 |
| ZNF638 | zinc finger protein 638 | 0.0439934 |
| THBS1 | thrombospondin 1 | 0.0437298 |
| INTS6 | integrator complex subunit 6 | 0.0411379 |
| ZBTB20 | zinc finger and BTB domain containing 20 | 0.0410225 |
| MYO1E | myosin IE | 0.0399716 |
| MSI2 | musashi RNA-binding protein 2 | 0.0386111 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | 0.0385957 |
| FAM13A | family with sequence similarity 13, member A | 0.0379481 |
| TRIO | trio Rho guanine nucleotide exchange factor | 0.0378219 |
| FLT1 | fms-related tyrosine kinase 1 | 0.0374327 |
| SDK1 | sidekick cell adhesion molecule 1 | 0.0373134 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0364583 |
| FERMT2 | fermitin family member 2 | 0.0363154 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0357522 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0347331 |
| ITPRID2 | ITPR interacting domain containing 2 | 0.0345633 |
| ASPH | aspartate beta-hydroxylase | 0.0340796 |
| SMYD3 | SET and MYND domain containing 3 | 0.0340576 |
| STK38L | serine/threonine kinase 38 like | 0.0339674 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0330589 |
| ACTN1 | actinin, alpha 1 | 0.0329162 |
| TPM1 | tropomyosin 1 (alpha) | 0.0328458 |
| MCL1 | myeloid cell leukemia 1 | 0.0327408 |
| SMURF2 | SMAD specific E3 ubiquitin protein ligase 2 | 0.0316777 |
| LRFN5 | leucine rich repeat and fibronectin type III domain containing 5 | 0.0316411 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0312309 |
| PCBP2 | poly(rC) binding protein 2 | 0.0310413 |
| PTPRE | protein tyrosine phosphatase, receptor type, E | 0.0307217 |
| PACS1 | phosphofurin acidic cluster sorting protein 1 | 0.0303958 |
| FNDC3A | fibronectin type III domain containing 3A | 0.0299618 |
| RIGI | RNA sensor RIG-I | 0.0299618 |
| MBD5 | methyl-CpG binding domain protein 5 | 0.0298326 |
| RAD51B | RAD51 paralog B | 0.0295358 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0294324 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0290273 |
| RBM20 | RNA binding motif protein 20 | 0.0289698 |
| GLCCI1 | glucocorticoid induced 1 | 0.0288685 |
| IMMP2L | IMP2 inner mitochondrial membrane peptidase-like (S. cerevisiae) | 0.0288587 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.028229 |
| PCBP3 | poly(rC) binding protein 3 | 0.0278451 |
| VPS13B | vacuolar protein sorting 13 homolog B (yeast) | 0.0277339 |
| DGKH | diacylglycerol kinase, eta | 0.0277256 |
| RABGAP1L | RAB GTPase activating protein 1-like | 0.027711 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0274984 |
| SP100 | SP100 nuclear antigen | 0.0272575 |
| MED13 | mediator complex subunit 13 | 0.0272349 |
| AHR | aryl hydrocarbon receptor | 0.0272111 |
| LIMA1 | LIM domain and actin binding 1 | 0.0270051 |
| SETBP1 | SET binding protein 1 | 0.0269884 |
| CTNND1 | catenin (cadherin-associated protein), delta 1 | 0.0262284 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | 0.0261871 |
| PTPRM | protein tyrosine phosphatase, receptor type, M | 0.0261056 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0260223 |
| PLOD2 | procollagen-lysine, 2-oxoglutarate 5-dioxygenase 2 | 0.025764 |
| ADARB1 | adenosine deaminase, RNA-specific, B1 | 0.0254274 |
| ZEB1 | zinc finger E-box binding homeobox 1 | 0.0253994 |
| ZC3H11A | zinc finger CCCH-type containing 11A | 0.0252043 |
| PDE10A | phosphodiesterase 10A | 0.0250845 |
| ARHGAP9 | Rho GTPase activating protein 9 | 0.024967 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0247782 |
| ASH1L | ash1 (absent, small, or homeotic)-like (Drosophila) | 0.0246992 |
| PCNX2 | pecanex 2 | 0.0245904 |
| SMAD3 | SMAD family member 3 | 0.0245622 |
| HOMER1 | homer scaffolding protein 1 | 0.0245134 |
| TCF12 | transcription factor 12 | 0.0244263 |
| HMBOX1 | homeobox containing 1 | 0.0242874 |
| LRBA | LPS-responsive vesicle trafficking, beach and anchor containing | 0.0237745 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0237663 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0235351 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0234914 |
| JMJD1C | jumonji domain containing 1C | 0.0234055 |
| EGFR | epidermal growth factor receptor | 0.0233648 |
| Symbol | Name | Standardized Value |
|---|---|---|
| IGF2 | insulin-like growth factor 2 | -0.374916 |
| DDX1 | DEAD (Asp-Glu-Ala-Asp) box helicase 1 | -0.362226 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0863915 |
| VIM | vimentin | -0.0727116 |
| PTMA | prothymosin, alpha | -0.07167 |
| SYT1 | synaptotagmin I | -0.057172 |
| COL1A1 | collagen, type I, alpha 1 | -0.0525802 |
| LPIN1 | lipin 1 | -0.0449077 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0387682 |
| ACTG1 | actin gamma 1 | -0.0386063 |
| GOLGA4 | golgin A4 | -0.0357608 |
| RPL34 | ribosomal protein L34 | -0.0321361 |
| TRIB2 | tribbles pseudokinase 2 | -0.0295348 |
| MAP1B | microtubule-associated protein 1B | -0.0292347 |
| RPL35A | ribosomal protein L35a | -0.02757 |
| CADM2 | cell adhesion molecule 2 | -0.0272166 |
| TMSB10 | thymosin beta 10 | -0.0271095 |
| RPLP1 | ribosomal protein, large, P1 | -0.0262783 |
| RPS19 | ribosomal protein S19 | -0.0253996 |
| NME2 | NME/NM23 nucleoside diphosphate kinase 2 | -0.0250836 |
| NREP | neuronal regeneration related protein | -0.023968 |
| TBX2 | T-box 2 | -0.0237466 |
| LGR5 | leucine-rich repeat containing G protein-coupled receptor 5 | -0.0236683 |
| CDC27 | cell division cycle 27 | -0.0229537 |
| KIF21A | kinesin family member 21A | -0.0228507 |
| HMGB2 | high mobility group box 2 | -0.022672 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0225219 |
| FOXK2 | forkhead box K2 | -0.021975 |
| WDR45B | WD repeat domain 45B | -0.0207374 |
| RPLP0 | ribosomal protein, large, P0 | -0.0205927 |
| NUCKS1 | nuclear casein kinase and cyclin-dependent kinase substrate 1 | -0.020133 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0200923 |
| RPS6 | ribosomal protein S6 | -0.0195986 |
| LMNA | lamin A/C | -0.0192616 |
| S100A6 | S100 calcium binding protein A6 | -0.0191 |
| CLTC | clathrin, heavy chain (Hc) | -0.0187823 |
| GNAS | GNAS complex locus | -0.0184495 |
| TCERG1 | transcription elongation regulator 1 | -0.0184478 |
| POTEF | POTE ankyrin domain family, member F | -0.0184446 |
| SOS1 | son of sevenless homolog 1 (Drosophila) | -0.0184065 |
| LMAN1 | lectin, mannose-binding, 1 | -0.0182522 |
| TUBB | tubulin, beta class I | -0.0181794 |
| VDAC1 | voltage-dependent anion channel 1 | -0.0180809 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0174925 |
| HNRNPK | heterogeneous nuclear ribonucleoprotein K | -0.0174788 |
| USP3 | ubiquitin specific peptidase 3 | -0.0174611 |
| PRPF8 | pre-mRNA processing factor 8 | -0.017302 |
| RPS11 | ribosomal protein S11 | -0.0169537 |
| RPL26 | ribosomal protein L26 | -0.0167913 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | -0.0165775 |
| RPL28 | ribosomal protein L28 | -0.0163668 |
| RACK1 | receptor for activated C kinase 1 | -0.0161423 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0160693 |
| WSB1 | WD repeat and SOCS box containing 1 | -0.0159608 |
| RPS24 | ribosomal protein S24 | -0.0159108 |
| CLINT1 | clathrin interactor 1 | -0.0158687 |
| ATF4 | activating transcription factor 4 | -0.0157612 |
| ETNK1 | ethanolamine kinase 1 | -0.015579 |
| SCN9A | sodium channel, voltage gated, type IX alpha subunit | -0.0154142 |
| FTL | ferritin, light polypeptide | -0.0153961 |
| VAT1 | vesicle amine transport 1 | -0.0153919 |
| LGALS1 | lectin, galactoside-binding, soluble, 1 | -0.0152707 |
| RPS21 | ribosomal protein S21 | -0.0149951 |
| CANX | calnexin | -0.0149101 |
| OGA | O-GlcNAcase | -0.0148721 |
| HMGA1 | high mobility group AT-hook 1 | -0.0148363 |
| ACBD3 | acyl-CoA binding domain containing 3 | -0.014809 |
| RPL19 | ribosomal protein L19 | -0.0147452 |
| SRP14 | signal recognition particle 14kDa (homologous Alu RNA binding protein) | -0.0146848 |
| MDM2 | MDM2 proto-oncogene, E3 ubiquitin protein ligase | -0.014477 |
| PRPF3 | pre-mRNA processing factor 3 | -0.0141307 |
| KPNB1 | karyopherin (importin) beta 1 | -0.0141302 |
| NPEPPS | aminopeptidase puromycin sensitive | -0.0140946 |
| TOB1 | transducer of ERBB2, 1 | -0.0140895 |
| FTH1 | ferritin, heavy polypeptide 1 | -0.0139863 |
| INSR | insulin receptor | -0.0139757 |
| P4HB | prolyl 4-hydroxylase, beta polypeptide | -0.0138957 |
| CCT8 | chaperonin containing TCP1, subunit 8 (theta) | -0.0138721 |
| RPL32 | ribosomal protein L32 | -0.0137883 |
| COL6A1 | collagen, type VI, alpha 1 | -0.0137548 |
| AFMID | arylformamidase | -0.0135944 |
| MYLK | myosin light chain kinase | -0.0135357 |
| GARS1 | glycyl-tRNA synthetase 1 | -0.013503 |
| RPL6 | ribosomal protein L6 | -0.0132461 |
| HIF1A | hypoxia inducible factor 1, alpha subunit (basic helix-loop-helix transcription factor) | -0.0131904 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0131662 |
| MORF4L1 | mortality factor 4 like 1 | -0.0131398 |
| ZFAND6 | zinc finger, AN1-type domain 6 | -0.0130842 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0130691 |
| TPST1 | tyrosylprotein sulfotransferase 1 | -0.0130356 |
| MMP2 | matrix metallopeptidase 2 | -0.0129777 |
| RPL4 | ribosomal protein L4 | -0.0129768 |
| SLC8A1 | solute carrier family 8 (sodium/calcium exchanger), member 1 | -0.0129766 |
| NUP160 | nucleoporin 160kDa | -0.0128352 |
| SETD5 | SET domain containing 5 | -0.0128194 |
| MAX | MYC associated factor X | -0.0127673 |
| TMEM123 | transmembrane protein 123 | -0.0127409 |
| COIL | coilin | -0.0127243 |
| BAZ2A | bromodomain adjacent to zinc finger domain, 2A | -0.0127221 |
| SMARCC1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily c, member 1 | -0.0126607 |
