| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in COLO 205 cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_COLO 205 drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.321936 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.115935 |
| MYO1E | myosin IE | 0.105031 |
| INTS6 | integrator complex subunit 6 | 0.104554 |
| ANXA2 | annexin A2 | 0.101655 |
| SMAD3 | SMAD family member 3 | 0.0962547 |
| DNAJC15 | DnaJ (Hsp40) homolog, subfamily C, member 15 | 0.095661 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0909869 |
| TPT1 | tumor protein, translationally-controlled 1 | 0.0904811 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0803308 |
| SQSTM1 | sequestosome 1 | 0.0743179 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0739323 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0732697 |
| EFNB2 | ephrin-B2 | 0.0713594 |
| MACC1 | metastasis associated in colon cancer 1 | 0.0663165 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0650414 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0603743 |
| ERN1 | endoplasmic reticulum to nucleus signaling 1 | 0.0597149 |
| VCL | vinculin | 0.0587581 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0587192 |
| SIPA1L2 | signal-induced proliferation-associated 1 like 2 | 0.0568531 |
| AREG | amphiregulin | 0.0551423 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0517881 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0511993 |
| LRCH1 | leucine-rich repeats and calponin homology (CH) domain containing 1 | 0.0507205 |
| EZR | ezrin | 0.0494487 |
| SPAG9 | sperm associated antigen 9 | 0.048782 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0464558 |
| ASPH | aspartate beta-hydroxylase | 0.0461962 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0450766 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0448231 |
| YAP1 | Yes-associated protein 1 | 0.0447956 |
| FZR1 | fizzy/cell division cycle 20 related 1 (Drosophila) | 0.0443345 |
| GOLGB1 | golgin B1 | 0.0440299 |
| PHF3 | PHD finger protein 3 | 0.0435453 |
| CANX | calnexin | 0.0433802 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0433291 |
| DUSP10 | dual specificity phosphatase 10 | 0.0423879 |
| ARIH1 | ariadne RBR E3 ubiquitin protein ligase 1 | 0.0415847 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0410908 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0410089 |
| CTBP2 | C-terminal binding protein 2 | 0.0406138 |
| AHI1 | Abelson helper integration site 1 | 0.0400582 |
| KYNU | kynureninase | 0.0397335 |
| CXCL8 | chemokine (C-X-C motif) ligand 8 | 0.0394968 |
| EREG | epiregulin | 0.0392516 |
| TRIM2 | tripartite motif containing 2 | 0.038145 |
| SHB | Src homology 2 domain containing adaptor protein B | 0.0378444 |
| ZNF292 | zinc finger protein 292 | 0.036758 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.036585 |
| ANKRD10 | ankyrin repeat domain 10 | 0.0363215 |
| LAMB3 | laminin, beta 3 | 0.0361392 |
| FOS | FBJ murine osteosarcoma viral oncogene homolog | 0.0357161 |
| TJP1 | tight junction protein 1 | 0.0352972 |
| RAB7A | RAB7A, member RAS oncogene family | 0.0344804 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | 0.0335519 |
| CATSPERB | catsper channel auxiliary subunit beta | 0.0333603 |
| VMP1 | vacuole membrane protein 1 | 0.032661 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0326458 |
| ELOF1 | elongation factor 1 homolog (S. cerevisiae) | 0.0320492 |
| PRAG1 | PEAK1 related, kinase-activating pseudokinase 1 | 0.0316243 |
| SIK3 | SIK family kinase 3 | 0.0311631 |
| ATF6 | activating transcription factor 6 | 0.0309478 |
| SLK | STE20-like kinase | 0.0302736 |
| DPP4 | dipeptidyl-peptidase 4 | 0.0301596 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0300885 |
| TM4SF1 | transmembrane 4 L six family member 1 | 0.030019 |
| AFF1 | AF4/FMR2 family, member 1 | 0.0299605 |
| USP53 | ubiquitin specific peptidase 53 | 0.0298489 |
| PDZD8 | PDZ domain containing 8 | 0.0297217 |
| SLC2A1 | solute carrier family 2 (facilitated glucose transporter), member 1 | 0.0296987 |
| DNAJC3 | DnaJ (Hsp40) homolog, subfamily C, member 3 | 0.028717 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0282441 |
| MCU | mitochondrial calcium uniporter | 0.0278824 |
| PMM2 | phosphomannomutase 2 | 0.0278711 |
| HKDC1 | hexokinase domain containing 1 | 0.0275732 |
| TNFRSF21 | tumor necrosis factor receptor superfamily, member 21 | 0.0274566 |
| SNTB1 | syntrophin, beta 1 (dystrophin-associated protein A1, 59kDa, basic component 1) | 0.0274154 |
| TNFAIP3 | tumor necrosis factor, alpha-induced protein 3 | 0.0271161 |
| TOX3 | TOX high mobility group box family member 3 | 0.0269567 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0269511 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0269026 |
| FNIP1 | folliculin interacting protein 1 | 0.0268556 |
| ADIPOR2 | adiponectin receptor 2 | 0.0260941 |
| DST | dystonin | 0.0257573 |
| LCN2 | lipocalin 2 | 0.0257373 |
| RAB10 | RAB10, member RAS oncogene family | 0.0252844 |
| RHPN2 | rhophilin, Rho GTPase binding protein 2 | 0.0252741 |
| HNRNPC | heterogeneous nuclear ribonucleoprotein C (C1/C2) | 0.0251209 |
| TUT7 | terminal uridylyl transferase 7 | 0.0247421 |
| RFFL | ring finger and FYVE-like domain containing E3 ubiquitin protein ligase | 0.0247293 |
| FNDC3A | fibronectin type III domain containing 3A | 0.02464 |
| LURAP1L | leucine rich adaptor protein 1-like | 0.0246245 |
| FNIP2 | folliculin interacting protein 2 | 0.024602 |
| CYSTM1 | cysteine-rich transmembrane module containing 1 | 0.0244353 |
| DCBLD2 | discoidin, CUB and LCCL domain containing 2 | 0.0244242 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0243127 |
| GOLGA2 | golgin A2 | 0.0242859 |
| YWHAZ | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, zeta | 0.0241858 |
| RND3 | Rho family GTPase 3 | 0.0240646 |
| Symbol | Name | Standardized Value |
|---|---|---|
| B2M | beta-2-microglobulin | -0.135705 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.110864 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0864731 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0788988 |
| LYZ | lysozyme | -0.070566 |
| HLA-B | major histocompatibility complex, class I, B | -0.0552376 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0512405 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0512131 |
| DDX60 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60 | -0.0455254 |
| MX1 | MX dynamin-like GTPase 1 | -0.0438818 |
| PLA2G2A | phospholipase A2, group IIA (platelets, synovial fluid) | -0.0412741 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0410305 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0409169 |
| NPSR1 | neuropeptide S receptor 1 | -0.0403453 |
| ERO1A | endoplasmic reticulum oxidoreductase 1 alpha | -0.0381039 |
| ELF3 | E74-like factor 3 (ets domain transcription factor, epithelial-specific ) | -0.0375736 |
| NDRG1 | N-myc downstream regulated 1 | -0.0375264 |
| TMSB10 | thymosin beta 10 | -0.0357348 |
| PKM | pyruvate kinase, muscle | -0.035621 |
| DDX60L | DEAD (Asp-Glu-Ala-Asp) box polypeptide 60-like | -0.0351114 |
| POTEF | POTE ankyrin domain family, member F | -0.0347576 |
| SORBS1 | sorbin and SH3 domain containing 1 | -0.0345854 |
| TXNIP | thioredoxin interacting protein | -0.0342492 |
| RPS6 | ribosomal protein S6 | -0.0339948 |
| RPLP1 | ribosomal protein, large, P1 | -0.0330761 |
| EGLN3 | egl-9 family hypoxia-inducible factor 3 | -0.0330456 |
| EGR1 | early growth response 1 | -0.0329646 |
| TSHZ2 | teashirt zinc finger homeobox 2 | -0.0326269 |
| PARP9 | poly (ADP-ribose) polymerase family, member 9 | -0.0321781 |
| CBFA2T2 | core-binding factor, runt domain, alpha subunit 2; translocated to, 2 | -0.0321539 |
| CST3 | cystatin C | -0.0314114 |
| DIAPH3 | diaphanous-related formin 3 | -0.030451 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0302987 |
| NCKAP5 | NCK-associated protein 5 | -0.0289092 |
| PARP4 | poly (ADP-ribose) polymerase family, member 4 | -0.0288432 |
| RHOBTB3 | Rho-related BTB domain containing 3 | -0.0282035 |
| EFHD2 | EF-hand domain family, member D2 | -0.0278339 |
| ARHGAP26 | Rho GTPase activating protein 26 | -0.0272355 |
| PTGR1 | prostaglandin reductase 1 | -0.0268801 |
| RPS19 | ribosomal protein S19 | -0.0264513 |
| TOP2A | topoisomerase (DNA) II alpha 170kDa | -0.0264382 |
| MUC13 | mucin 13, cell surface associated | -0.0262098 |
| SPATS2L | spermatogenesis associated, serine-rich 2-like | -0.026116 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0259156 |
| EIF2AK2 | eukaryotic translation initiation factor 2-alpha kinase 2 | -0.0258146 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | -0.0257976 |
| PTMA | prothymosin, alpha | -0.0249566 |
| OASL | 2'-5'-oligoadenylate synthetase-like | -0.0247869 |
| HLA-C | major histocompatibility complex, class I, C | -0.0247055 |
| SSH2 | slingshot protein phosphatase 2 | -0.0246231 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0245727 |
| CSTB | cystatin B (stefin B) | -0.0245699 |
| RPL35A | ribosomal protein L35a | -0.0242324 |
| MKI67 | marker of proliferation Ki-67 | -0.0241887 |
| PTBP3 | polypyrimidine tract binding protein 3 | -0.0241391 |
| GNAS | GNAS complex locus | -0.0236978 |
| MPHOSPH8 | M-phase phosphoprotein 8 | -0.0236238 |
| ITGB4 | integrin, beta 4 | -0.0229186 |
| APOL1 | apolipoprotein L, 1 | -0.0227023 |
| ANXA4 | annexin A4 | -0.0224603 |
| PRKCA | protein kinase C, alpha | -0.0224197 |
| WDR45B | WD repeat domain 45B | -0.022386 |
| ZNFX1 | zinc finger, NFX1-type containing 1 | -0.0221947 |
| PTEN | phosphatase and tensin homolog | -0.0220543 |
| TMEM165 | transmembrane protein 165 | -0.0215827 |
| IFIT3 | interferon-induced protein with tetratricopeptide repeats 3 | -0.0209736 |
| MT2A | metallothionein 2A | -0.0209613 |
| DSCAML1 | Down syndrome cell adhesion molecule like 1 | -0.0207257 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0206311 |
| RBCK1 | RanBP-type and C3HC4-type zinc finger containing 1 | -0.0205869 |
| STS | steroid sulfatase (microsomal), isozyme S | -0.020378 |
| ACSL3 | acyl-CoA synthetase long-chain family member 3 | -0.0203189 |
| SCARB1 | scavenger receptor class B, member 1 | -0.0201865 |
| ZMYM2 | zinc finger, MYM-type 2 | -0.0200772 |
| UBR2 | ubiquitin protein ligase E3 component n-recognin 2 | -0.0200023 |
| GCC2 | GRIP and coiled-coil domain containing 2 | -0.0199428 |
| DDX17 | DEAD (Asp-Glu-Ala-Asp) box helicase 17 | -0.0199424 |
| PAN3 | PAN3 poly(A) specific ribonuclease subunit | -0.0195398 |
| RAD54B | RAD54 homolog B (S. cerevisiae) | -0.0195168 |
| VEGFA | vascular endothelial growth factor A | -0.019454 |
| VDAC1 | voltage-dependent anion channel 1 | -0.019323 |
| HMGB1 | high mobility group box 1 | -0.0192932 |
| S100A6 | S100 calcium binding protein A6 | -0.019277 |
| TPM4 | tropomyosin 4 | -0.0192685 |
| CCNL1 | cyclin L1 | -0.0190827 |
| CLDN7 | claudin 7 | -0.0189543 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0189057 |
| TPI1 | triosephosphate isomerase 1 | -0.018646 |
| APOL6 | apolipoprotein L, 6 | -0.0183293 |
| RNF43 | ring finger protein 43 | -0.0183023 |
| CTSD | cathepsin D | -0.0181404 |
| PLCH1 | phospholipase C, eta 1 | -0.018073 |
| BRCA2 | breast cancer 2, early onset | -0.0180608 |
| ZKSCAN1 | zinc finger with KRAB and SCAN domains 1 | -0.0180167 |
| CLDN4 | claudin 4 | -0.0179004 |
| NCOR1 | nuclear receptor corepressor 1 | -0.0178021 |
| MUC1 | mucin 1, cell surface associated | -0.0177768 |
| GFPT1 | glutamine--fructose-6-phosphate transaminase 1 | -0.017741 |
| DGKH | diacylglycerol kinase, eta | -0.0176548 |
| RPS28 | ribosomal protein S28 | -0.0175197 |
