| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in Hs 766T cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_Hs 766T drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| TPT1 | tumor protein, translationally-controlled 1 | 0.102204 |
| PALM2AKAP2 | PALM2 and AKAP2 fusion | 0.0941321 |
| MEF2A | myocyte enhancer factor 2A | 0.0832747 |
| LMO7 | LIM domain 7 | 0.0642137 |
| RAI14 | retinoic acid induced 14 | 0.0600232 |
| KCNK1 | potassium channel, two pore domain subfamily K, member 1 | 0.0598938 |
| JMJD1C | jumonji domain containing 1C | 0.0577369 |
| MTSS1 | metastasis suppressor 1 | 0.0556257 |
| IFIT2 | interferon-induced protein with tetratricopeptide repeats 2 | 0.0528863 |
| CLU | clusterin | 0.0519826 |
| BCAR3 | breast cancer anti-estrogen resistance 3 | 0.0495817 |
| VCL | vinculin | 0.0477902 |
| EXT1 | exostosin glycosyltransferase 1 | 0.0474976 |
| SLK | STE20-like kinase | 0.045844 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0450418 |
| RNF217 | ring finger protein 217 | 0.0436393 |
| LAMC1 | laminin, gamma 1 (formerly LAMB2) | 0.0432974 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0430734 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0429492 |
| SQSTM1 | sequestosome 1 | 0.0428507 |
| RICTOR | RPTOR independent companion of MTOR, complex 2 | 0.0419643 |
| DSPP | dentin sialophosphoprotein | 0.041876 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0410114 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0401585 |
| PDE4D | phosphodiesterase 4D, cAMP-specific | 0.0401006 |
| CD44 | CD44 molecule (Indian blood group) | 0.0395373 |
| RAB10 | RAB10, member RAS oncogene family | 0.0394657 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0390813 |
| CSNK1A1 | casein kinase 1, alpha 1 | 0.0388919 |
| KMT2C | lysine (K)-specific methyltransferase 2C | 0.0379944 |
| TXNIP | thioredoxin interacting protein | 0.0363746 |
| DYRK1A | dual-specificity tyrosine-(Y)-phosphorylation regulated kinase 1A | 0.0349558 |
| MT1E | metallothionein 1E | 0.0348465 |
| SEPTIN9 | septin 9 | 0.03474 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0339245 |
| APP | amyloid beta (A4) precursor protein | 0.0334886 |
| ESYT2 | extended synaptotagmin-like protein 2 | 0.0334112 |
| IFI44L | interferon-induced protein 44-like | 0.0325097 |
| FOXO1 | forkhead box O1 | 0.0314926 |
| SAMD9 | sterile alpha motif domain containing 9 | 0.0305724 |
| ANKRD12 | ankyrin repeat domain 12 | 0.0305617 |
| DIAPH1 | diaphanous-related formin 1 | 0.0305222 |
| PDIA3 | protein disulfide isomerase family A, member 3 | 0.0292119 |
| NFATC2 | nuclear factor of activated T-cells, cytoplasmic, calcineurin-dependent 2 | 0.0291221 |
| DDX5 | DEAD (Asp-Glu-Ala-Asp) box helicase 5 | 0.0287755 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0285784 |
| FRMD6 | FERM domain containing 6 | 0.0280127 |
| EPS8 | epidermal growth factor receptor pathway substrate 8 | 0.0278718 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0278237 |
| B4GALT5 | UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 5 | 0.0272444 |
| EFNA5 | ephrin-A5 | 0.0271903 |
| CALB1 | calbindin 1, 28kDa | 0.0268395 |
| MYOF | myoferlin | 0.0264184 |
| TBC1D8 | TBC1 domain family, member 8 (with GRAM domain) | 0.0258437 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0258359 |
| GRB10 | growth factor receptor-bound protein 10 | 0.0257767 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0252663 |
| PARP14 | poly (ADP-ribose) polymerase family, member 14 | 0.0250461 |
| TPM3 | tropomyosin 3 | 0.0250087 |
| ABCA1 | ATP-binding cassette, sub-family A (ABC1), member 1 | 0.0249265 |
| ZC3HAV1 | zinc finger CCCH-type, antiviral 1 | 0.0245111 |
| NAP1L1 | nucleosome assembly protein 1-like 1 | 0.024069 |
| IFI44 | interferon-induced protein 44 | 0.0239942 |
| PSD3 | pleckstrin and Sec7 domain containing 3 | 0.0236517 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0235749 |
| RIGI | RNA sensor RIG-I | 0.0234774 |
| GOLGB1 | golgin B1 | 0.0233876 |
| SFPQ | splicing factor proline/glutamine-rich | 0.0233474 |
| MSN | moesin | 0.0229234 |
| MATR3 | matrin 3 | 0.0228892 |
| CPEB2 | cytoplasmic polyadenylation element binding protein 2 | 0.022886 |
| ELF2 | E74-like factor 2 (ets domain transcription factor) | 0.0227027 |
| ABTB2 | ankyrin repeat and BTB (POZ) domain containing 2 | 0.022619 |
| CAMK1D | calcium/calmodulin-dependent protein kinase ID | 0.0225637 |
| HLA-E | major histocompatibility complex, class I, E | 0.0225409 |
| DSCAM | Down syndrome cell adhesion molecule | 0.0224756 |
| FHIP1A | FHF complex subunit HOOK interacting protein 1A | 0.0222546 |
| ITPRIPL2 | inositol 1,4,5-trisphosphate receptor interacting protein-like 2 | 0.021999 |
| LGR4 | leucine-rich repeat containing G protein-coupled receptor 4 | 0.021311 |
| PRRC2C | proline-rich coiled-coil 2C | 0.0212933 |
| UBE2H | ubiquitin-conjugating enzyme E2H | 0.0212766 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0210072 |
| KLF10 | Kruppel-like factor 10 | 0.020993 |
| INPP5F | inositol polyphosphate-5-phosphatase F | 0.0209117 |
| PMAIP1 | phorbol-12-myristate-13-acetate-induced protein 1 | 0.0208109 |
| GBP2 | guanylate binding protein 2, interferon-inducible | 0.0207423 |
| LPGAT1 | lysophosphatidylglycerol acyltransferase 1 | 0.0207311 |
| DHX34 | DEAH (Asp-Glu-Ala-His) box polypeptide 34 | 0.020697 |
| LUZP1 | leucine zipper protein 1 | 0.0205992 |
| SET | SET nuclear proto-oncogene | 0.0205801 |
| YTHDC1 | YTH domain containing 1 | 0.0205241 |
| ELL2 | elongation factor, RNA polymerase II, 2 | 0.0199982 |
| KMT2E | lysine (K)-specific methyltransferase 2E | 0.0199465 |
| SLC12A2 | solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 0.0196672 |
| MED13L | mediator complex subunit 13-like | 0.0195594 |
| MT1G | metallothionein 1G | 0.0195355 |
| ATP2B1 | ATPase, Ca++ transporting, plasma membrane 1 | 0.019528 |
| ADM | adrenomedullin | 0.0194993 |
| EHBP1L1 | EH domain binding protein 1-like 1 | 0.0194751 |
| TBL1XR1 | transducin (beta)-like 1 X-linked receptor 1 | 0.019403 |
| Symbol | Name | Standardized Value |
|---|---|---|
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.218875 |
| NDRG1 | N-myc downstream regulated 1 | -0.142271 |
| TMSB10 | thymosin beta 10 | -0.136888 |
| FLNB | filamin B, beta | -0.127532 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | -0.117054 |
| IGF2 | insulin-like growth factor 2 | -0.104171 |
| POTEF | POTE ankyrin domain family, member F | -0.101657 |
| SULF1 | sulfatase 1 | -0.100656 |
| TIMP3 | TIMP metallopeptidase inhibitor 3 | -0.0939431 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0911017 |
| S100A10 | S100 calcium binding protein A10 | -0.0892029 |
| TMSB4X | thymosin beta 4, X-linked | -0.0867867 |
| GNAS | GNAS complex locus | -0.0804308 |
| RPLP1 | ribosomal protein, large, P1 | -0.0759651 |
| PKM | pyruvate kinase, muscle | -0.0671424 |
| RPS6 | ribosomal protein S6 | -0.0669786 |
| ENO1 | enolase 1, (alpha) | -0.0658787 |
| HLA-B | major histocompatibility complex, class I, B | -0.0656099 |
| TRIO | trio Rho guanine nucleotide exchange factor | -0.0653638 |
| PTMA | prothymosin, alpha | -0.0645409 |
| RPS19 | ribosomal protein S19 | -0.0626063 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0624517 |
| HSPA5 | heat shock 70kDa protein 5 (glucose-regulated protein, 78kDa) | -0.0608136 |
| S100A2 | S100 calcium binding protein A2 | -0.0595213 |
| RPLP2 | ribosomal protein, large, P2 | -0.0565063 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | -0.0559853 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0554505 |
| LMNA | lamin A/C | -0.0554358 |
| SH3BGRL3 | SH3 domain binding glutamate-rich protein like 3 | -0.0541424 |
| RPL8 | ribosomal protein L8 | -0.0523029 |
| RPL35A | ribosomal protein L35a | -0.0514904 |
| CNRIP1 | cannabinoid receptor interacting protein 1 | -0.0474051 |
| ANXA2 | annexin A2 | -0.0466491 |
| HSPG2 | heparan sulfate proteoglycan 2 | -0.0455933 |
| LDHA | lactate dehydrogenase A | -0.0449962 |
| RPL7A | ribosomal protein L7a | -0.0448007 |
| RPL5 | ribosomal protein L5 | -0.0444366 |
| IL1RAPL1 | interleukin 1 receptor accessory protein-like 1 | -0.0438238 |
| MAML2 | mastermind-like 2 (Drosophila) | -0.0433535 |
| HIVEP3 | human immunodeficiency virus type I enhancer binding protein 3 | -0.0429533 |
| CYB5R3 | cytochrome b5 reductase 3 | -0.042904 |
| HM13 | histocompatibility (minor) 13 | -0.0427848 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0410519 |
| RPS29 | ribosomal protein S29 | -0.0409842 |
| RPL32 | ribosomal protein L32 | -0.0408713 |
| SLC25A37 | solute carrier family 25 (mitochondrial iron transporter), member 37 | -0.0408541 |
| MKI67 | marker of proliferation Ki-67 | -0.0398483 |
| ANLN | anillin, actin binding protein | -0.0394951 |
| RPL11 | ribosomal protein L11 | -0.0393835 |
| VDAC1 | voltage-dependent anion channel 1 | -0.038641 |
| RPS21 | ribosomal protein S21 | -0.0384697 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.0383057 |
| MORF4L2 | mortality factor 4 like 2 | -0.0374964 |
| FSCN1 | fascin actin-bundling protein 1 | -0.0372534 |
| ALDH3A1 | aldehyde dehydrogenase 3 family, member A1 | -0.0368881 |
| YBX1 | Y box binding protein 1 | -0.0366999 |
| S100A11 | S100 calcium binding protein A11 | -0.0365539 |
| CDK6 | cyclin-dependent kinase 6 | -0.0363282 |
| WASF2 | WAS protein family, member 2 | -0.0362217 |
| EEF1D | eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein) | -0.0355984 |
| ID1 | inhibitor of DNA binding 1, dominant negative helix-loop-helix protein | -0.0354674 |
| EIF2S2 | eukaryotic translation initiation factor 2, subunit 2 beta, 38kDa | -0.0354094 |
| HSP90B1 | heat shock protein 90kDa beta (Grp94), member 1 | -0.035205 |
| CAVIN1 | caveolae associated protein 1 | -0.0344671 |
| RPL27A | ribosomal protein L27a | -0.034379 |
| S100A4 | S100 calcium binding protein A4 | -0.034303 |
| ACTG1 | actin gamma 1 | -0.0341167 |
| SLCO4A1 | solute carrier organic anion transporter family, member 4A1 | -0.0335034 |
| KCNMA1 | potassium channel, calcium activated large conductance subfamily M alpha, member 1 | -0.0327784 |
| RPS16 | ribosomal protein S16 | -0.032747 |
| PGK1 | phosphoglycerate kinase 1 | -0.0327055 |
| RPS23 | ribosomal protein S23 | -0.0325868 |
| COX4I1 | cytochrome c oxidase subunit IV isoform 1 | -0.0324835 |
| IGFBP4 | insulin-like growth factor binding protein 4 | -0.0323511 |
| RPL34 | ribosomal protein L34 | -0.0323393 |
| PFN1 | profilin 1 | -0.0318908 |
| MT2A | metallothionein 2A | -0.0314317 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0311896 |
| RPL13A | ribosomal protein L13a | -0.0311813 |
| S100A6 | S100 calcium binding protein A6 | -0.0309004 |
| RPL30 | ribosomal protein L30 | -0.0306401 |
| EFHD2 | EF-hand domain family, member D2 | -0.0304326 |
| DPYD | dihydropyrimidine dehydrogenase | -0.0300462 |
| COPB1 | coatomer protein complex, subunit beta 1 | -0.0299607 |
| RPL19 | ribosomal protein L19 | -0.0295422 |
| MT1X | metallothionein 1X | -0.0293778 |
| FLNA | filamin A, alpha | -0.0292895 |
| RPS13 | ribosomal protein S13 | -0.0291498 |
| RPL37A | ribosomal protein L37a | -0.028988 |
| IRF2BP2 | interferon regulatory factor 2 binding protein 2 | -0.0289318 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0286775 |
| CST3 | cystatin C | -0.0283559 |
| BSG | basigin (Ok blood group) | -0.0283343 |
| KDM3A | lysine (K)-specific demethylase 3A | -0.0282758 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0282217 |
| EPHA2 | EPH receptor A2 | -0.028143 |
| LUC7L3 | LUC7-like 3 (S. cerevisiae) | -0.0273221 |
| RPS27 | ribosomal protein S27 | -0.0272675 |
| B2M | beta-2-microglobulin | -0.0268754 |
| IER3 | immediate early response 3 | -0.0267942 |
