| Dataset | Tahoe Therapeutics Tahoe 100M Perturbation Atlas |
| Category | transcriptomics |
| Type | cell type |
| Description | Demeclocycline perturbation in KATO III cell line (Tahoe Therapeutics) |
| Similar Terms | |
| Downloads & Tools |
200 genes differentially expressed following the Demeclocycline_KATO III drug perturbation from the Tahoe Therapeutics Tahoe 100M Perturbation Atlas dataset.
| Symbol | Name | Standardized Value |
|---|---|---|
| LMO7 | LIM domain 7 | 0.153968 |
| AHNAK | AHNAK nucleoprotein | 0.0774329 |
| APLP2 | amyloid beta (A4) precursor-like protein 2 | 0.0648888 |
| SPTBN1 | spectrin, beta, non-erythrocytic 1 | 0.0632821 |
| HSP90AA1 | heat shock protein 90kDa alpha (cytosolic), class A member 1 | 0.0614801 |
| MBNL2 | muscleblind-like splicing regulator 2 | 0.0614586 |
| ANXA1 | annexin A1 | 0.0604413 |
| HNRNPA2B1 | heterogeneous nuclear ribonucleoprotein A2/B1 | 0.0580692 |
| DSPP | dentin sialophosphoprotein | 0.0560878 |
| ITGA6 | integrin, alpha 6 | 0.055985 |
| GPRC5A | G protein-coupled receptor, class C, group 5, member A | 0.0556566 |
| MYOF | myoferlin | 0.052017 |
| ASPH | aspartate beta-hydroxylase | 0.0512618 |
| MYH9 | myosin, heavy chain 9, non-muscle | 0.0508404 |
| FAT1 | FAT atypical cadherin 1 | 0.0480923 |
| FNDC3B | fibronectin type III domain containing 3B | 0.0469373 |
| EMP1 | epithelial membrane protein 1 | 0.0462203 |
| HSP90AB1 | heat shock protein 90kDa alpha (cytosolic), class B member 1 | 0.0449918 |
| EZR | ezrin | 0.0428338 |
| AKAP13 | A kinase (PRKA) anchor protein 13 | 0.0419946 |
| SMAD3 | SMAD family member 3 | 0.0406061 |
| SPTAN1 | spectrin, alpha, non-erythrocytic 1 | 0.0405345 |
| PPP1R15A | protein phosphatase 1, regulatory subunit 15A | 0.0383782 |
| PLEC | plectin | 0.0376429 |
| GDA | guanine deaminase | 0.037619 |
| AHR | aryl hydrocarbon receptor | 0.0355573 |
| ITGA2 | integrin, alpha 2 (CD49B, alpha 2 subunit of VLA-2 receptor) | 0.0354554 |
| GULP1 | GULP, engulfment adaptor PTB domain containing 1 | 0.0354347 |
| NCEH1 | neutral cholesterol ester hydrolase 1 | 0.0351783 |
| SEPTIN9 | septin 9 | 0.0349889 |
| ZSWIM6 | zinc finger, SWIM-type containing 6 | 0.0334271 |
| DST | dystonin | 0.033154 |
| ASAP2 | ArfGAP with SH3 domain, ankyrin repeat and PH domain 2 | 0.0328465 |
| CTNNA1 | catenin (cadherin-associated protein), alpha 1, 102kDa | 0.0323241 |
| NEDD4L | neural precursor cell expressed, developmentally down-regulated 4-like, E3 ubiquitin protein ligase | 0.030986 |
| INTS6 | integrator complex subunit 6 | 0.0307691 |
| CD55 | CD55 molecule, decay accelerating factor for complement (Cromer blood group) | 0.0303732 |
| NAB1 | NGFI-A binding protein 1 (EGR1 binding protein 1) | 0.0288482 |
| CYP3A5 | cytochrome P450, family 3, subfamily A, polypeptide 5 | 0.0287007 |
| UBASH3B | ubiquitin associated and SH3 domain containing B | 0.028583 |
| ATXN1 | ataxin 1 | 0.0271707 |
| CALM2 | calmodulin 2 (phosphorylase kinase, delta) | 0.0270442 |
| CTNNB1 | catenin (cadherin-associated protein), beta 1, 88kDa | 0.0266915 |
| CEMIP | cell migration inducing protein, hyaluronan binding | 0.026625 |
| MBNL1 | muscleblind-like splicing regulator 1 | 0.0261547 |
| LPP | LIM domain containing preferred translocation partner in lipoma | 0.0260789 |
| SNX9 | sorting nexin 9 | 0.0260742 |
| SLTM | SAFB-like, transcription modulator | 0.025688 |
| CRIM1 | cysteine rich transmembrane BMP regulator 1 (chordin-like) | 0.0255188 |
| MPRIP | myosin phosphatase Rho interacting protein | 0.0253051 |
| PTPRK | protein tyrosine phosphatase, receptor type, K | 0.0252487 |
| EEPD1 | endonuclease/exonuclease/phosphatase family domain containing 1 | 0.0248676 |
| CTBP2 | C-terminal binding protein 2 | 0.0248564 |
| PDLIM5 | PDZ and LIM domain 5 | 0.0244658 |
| HUWE1 | HECT, UBA and WWE domain containing 1, E3 ubiquitin protein ligase | 0.0242241 |
| SLC38A2 | solute carrier family 38, member 2 | 0.0241365 |
| GOLGB1 | golgin B1 | 0.023438 |
| TOM1L2 | target of myb1-like 2 (chicken) | 0.023371 |
| LAMB3 | laminin, beta 3 | 0.023212 |
| PTPRN2 | protein tyrosine phosphatase, receptor type, N polypeptide 2 | 0.0230433 |
| USP9X | ubiquitin specific peptidase 9, X-linked | 0.0226916 |
| TEAD1 | TEA domain family member 1 (SV40 transcriptional enhancer factor) | 0.0225145 |
| KLF5 | Kruppel-like factor 5 (intestinal) | 0.0220991 |
| NFAT5 | nuclear factor of activated T-cells 5, tonicity-responsive | 0.0219234 |
| AGAP1 | ArfGAP with GTPase domain, ankyrin repeat and PH domain 1 | 0.0218542 |
| DOCK5 | dedicator of cytokinesis 5 | 0.0216138 |
| HSPA8 | heat shock 70kDa protein 8 | 0.0213709 |
| EFNB2 | ephrin-B2 | 0.0208177 |
| CEMIP2 | cell migration inducing hyaluronidase 2 | 0.0207995 |
| ARHGAP26 | Rho GTPase activating protein 26 | 0.0207104 |
| EPB41L2 | erythrocyte membrane protein band 4.1-like 2 | 0.0206556 |
| HNRNPA1 | heterogeneous nuclear ribonucleoprotein A1 | 0.0206184 |
| DDX6 | DEAD (Asp-Glu-Ala-Asp) box helicase 6 | 0.0205329 |
| EHBP1 | EH domain binding protein 1 | 0.0202708 |
| MACF1 | microtubule-actin crosslinking factor 1 | 0.0200683 |
| HKDC1 | hexokinase domain containing 1 | 0.0199803 |
| OSBPL10 | oxysterol binding protein-like 10 | 0.0198179 |
| HNRNPU | heterogeneous nuclear ribonucleoprotein U (scaffold attachment factor A) | 0.0193431 |
| RASEF | RAS and EF-hand domain containing | 0.0193035 |
| ITGB1 | integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12) | 0.0192877 |
| DDX3X | DEAD (Asp-Glu-Ala-Asp) box helicase 3, X-linked | 0.0192864 |
| KIF16B | kinesin family member 16B | 0.0190519 |
| EFNA5 | ephrin-A5 | 0.0189199 |
| ADAM9 | ADAM metallopeptidase domain 9 | 0.018859 |
| HIVEP2 | human immunodeficiency virus type I enhancer binding protein 2 | 0.0188553 |
| ANXA2 | annexin A2 | 0.018691 |
| EGFR | epidermal growth factor receptor | 0.0186734 |
| TES | testin LIM domain protein | 0.0185729 |
| BAIAP2L1 | BAI1-associated protein 2-like 1 | 0.0184846 |
| CAPN8 | calpain 8 | 0.0183681 |
| KLHL29 | kelch-like family member 29 | 0.018241 |
| IQGAP1 | IQ motif containing GTPase activating protein 1 | 0.017776 |
| ATP11A | ATPase, class VI, type 11A | 0.0176861 |
| TSC22D2 | TSC22 domain family, member 2 | 0.0174435 |
| GCLC | glutamate-cysteine ligase, catalytic subunit | 0.0174306 |
| EEF1A1 | eukaryotic translation elongation factor 1 alpha 1 | 0.0173955 |
| APP | amyloid beta (A4) precursor protein | 0.0173784 |
| MGAT5 | mannosyl (alpha-1,6-)-glycoprotein beta-1,6-N-acetyl-glucosaminyltransferase | 0.0172223 |
| FNIP1 | folliculin interacting protein 1 | 0.017218 |
| POF1B | premature ovarian failure, 1B | 0.017137 |
| Symbol | Name | Standardized Value |
|---|---|---|
| NPSR1 | neuropeptide S receptor 1 | -0.136857 |
| CEACAM5 | carcinoembryonic antigen-related cell adhesion molecule 5 | -0.102557 |
| PTMA | prothymosin, alpha | -0.102189 |
| GAPDH | glyceraldehyde-3-phosphate dehydrogenase | -0.0785548 |
| TMSB10 | thymosin beta 10 | -0.0746669 |
| RPL35A | ribosomal protein L35a | -0.058493 |
| CEACAM6 | carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) | -0.0490938 |
| S100A6 | S100 calcium binding protein A6 | -0.0479135 |
| RPS6 | ribosomal protein S6 | -0.0470313 |
| FGFR2 | fibroblast growth factor receptor 2 | -0.0468718 |
| HSD17B12 | hydroxysteroid (17-beta) dehydrogenase 12 | -0.0464127 |
| B2M | beta-2-microglobulin | -0.0463419 |
| ACTG1 | actin gamma 1 | -0.0400118 |
| GMDS | GDP-mannose 4,6-dehydratase | -0.0355564 |
| S100A10 | S100 calcium binding protein A10 | -0.0345461 |
| RPS25 | ribosomal protein S25 | -0.033755 |
| POTEF | POTE ankyrin domain family, member F | -0.0328848 |
| SCD | stearoyl-CoA desaturase (delta-9-desaturase) | -0.0320423 |
| RPS24 | ribosomal protein S24 | -0.031692 |
| AGR2 | anterior gradient 2 | -0.0292009 |
| ACACA | acetyl-CoA carboxylase alpha | -0.0290013 |
| TMEM123 | transmembrane protein 123 | -0.0287957 |
| LOC112694756 | uncharaterized LOC112694756 | -0.0286562 |
| WDR45B | WD repeat domain 45B | -0.0274927 |
| WARS1 | tryptophanyl-tRNA synthetase 1 | -0.027468 |
| RAB7A | RAB7A, member RAS oncogene family | -0.0274563 |
| LLGL2 | lethal giant larvae homolog 2 (Drosophila) | -0.0273867 |
| IFI6 | interferon, alpha-inducible protein 6 | -0.0266496 |
| PPDPF | pancreatic progenitor cell differentiation and proliferation factor | -0.0265707 |
| TPM4 | tropomyosin 4 | -0.0263333 |
| HLA-B | major histocompatibility complex, class I, B | -0.0259317 |
| KLK10 | kallikrein-related peptidase 10 | -0.0256942 |
| MUC17 | mucin 17, cell surface associated | -0.0254765 |
| PLSCR1 | phospholipid scramblase 1 | -0.0254678 |
| RPS19 | ribosomal protein S19 | -0.0253502 |
| GPX2 | glutathione peroxidase 2 | -0.0249082 |
| RPS3 | ribosomal protein S3 | -0.0248259 |
| S100A11 | S100 calcium binding protein A11 | -0.024727 |
| RPLP1 | ribosomal protein, large, P1 | -0.0241097 |
| LYZ | lysozyme | -0.024004 |
| C6ORF132 | chromosome 6 open reading frame 132 | -0.0237777 |
| EPCAM | epithelial cell adhesion molecule | -0.0237134 |
| ZFP36L2 | ZFP36 ring finger protein-like 2 | -0.0230679 |
| RPL34 | ribosomal protein L34 | -0.0227173 |
| DLG1 | discs, large homolog 1 (Drosophila) | -0.0226471 |
| FDFT1 | farnesyl-diphosphate farnesyltransferase 1 | -0.0225512 |
| SLC6A14 | solute carrier family 6 (amino acid transporter), member 14 | -0.022415 |
| HLA-E | major histocompatibility complex, class I, E | -0.0222483 |
| LOC102724023 | ES1 protein homolog, mitochondrial | -0.0222 |
| EGR1 | early growth response 1 | -0.021642 |
| TNFRSF10B | tumor necrosis factor receptor superfamily, member 10b | -0.0215262 |
| IFI27 | interferon, alpha-inducible protein 27 | -0.0212712 |
| S100A9 | S100 calcium binding protein A9 | -0.0208145 |
| RPS16 | ribosomal protein S16 | -0.0206855 |
| HMGB1 | high mobility group box 1 | -0.0206341 |
| KRT8 | keratin 8, type II | -0.0205432 |
| IFITM3 | interferon induced transmembrane protein 3 | -0.0204998 |
| PABPC1 | poly(A) binding protein, cytoplasmic 1 | -0.0203046 |
| RPL19 | ribosomal protein L19 | -0.020301 |
| ATP1B1 | ATPase, Na+/K+ transporting, beta 1 polypeptide | -0.0202462 |
| CHCHD2 | coiled-coil-helix-coiled-coil-helix domain containing 2 | -0.0200623 |
| RPL36A | ribosomal protein L36a | -0.0200414 |
| INSIG1 | insulin induced gene 1 | -0.0199767 |
| RPL30 | ribosomal protein L30 | -0.0199196 |
| PRSS3 | protease, serine, 3 | -0.0198392 |
| RRBP1 | ribosome binding protein 1 | -0.0198386 |
| ITFG1 | integrin alpha FG-GAP repeat containing 1 | -0.0197978 |
| MUC1 | mucin 1, cell surface associated | -0.0196158 |
| ATP5F1B | ATP synthase F1 subunit beta | -0.0195382 |
| SULF2 | sulfatase 2 | -0.019392 |
| STAT1 | signal transducer and activator of transcription 1, 91kDa | -0.0193482 |
| RPS8 | ribosomal protein S8 | -0.019143 |
| ITGB4 | integrin, beta 4 | -0.0190969 |
| ZMYND8 | zinc finger, MYND-type containing 8 | -0.0188367 |
| CAMKMT | calmodulin-lysine N-methyltransferase | -0.018624 |
| CD46 | CD46 molecule, complement regulatory protein | -0.0185945 |
| CELF1 | CUGBP, Elav-like family member 1 | -0.0184164 |
| RPS27A | ribosomal protein S27a | -0.018351 |
| XAF1 | XIAP associated factor 1 | -0.0180336 |
| PIAS1 | protein inhibitor of activated STAT, 1 | -0.0178287 |
| COX5A | cytochrome c oxidase subunit Va | -0.0177471 |
| IRF1 | interferon regulatory factor 1 | -0.017664 |
| EPSTI1 | epithelial stromal interaction 1 (breast) | -0.0176507 |
| CEACAM1 | carcinoembryonic antigen-related cell adhesion molecule 1 (biliary glycoprotein) | -0.0176313 |
| RPL37A | ribosomal protein L37a | -0.017517 |
| UGGT2 | UDP-glucose glycoprotein glucosyltransferase 2 | -0.0175078 |
| SLC25A5 | solute carrier family 25 (mitochondrial carrier; adenine nucleotide translocator), member 5 | -0.0174158 |
| YWHAB | tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta | -0.01729 |
| IFITM1 | interferon induced transmembrane protein 1 | -0.0172198 |
| RPL23 | ribosomal protein L23 | -0.0171019 |
| NECTIN2 | nectin cell adhesion molecule 2 | -0.0170905 |
| TMEM45B | transmembrane protein 45B | -0.0169912 |
| SREBF2 | sterol regulatory element binding transcription factor 2 | -0.0167822 |
| CD2AP | CD2-associated protein | -0.016523 |
| RPS21 | ribosomal protein S21 | -0.0162544 |
| RPL9 | ribosomal protein L9 | -0.0160994 |
| SLC38A1 | solute carrier family 38, member 1 | -0.0158994 |
| H3-3B | H3.3 histone B | -0.015812 |
| FASN | fatty acid synthase | -0.0157771 |
| ARPC2 | actin related protein 2/3 complex, subunit 2, 34kDa | -0.0156022 |
